reduction dexrazoxane (Intravenous route) dex-ray-ZOX-ane Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Totect Zinecard Available Dosage Forms: Powder for Solution Therapeutic Class: Cardioprotective Agent Slideshow Diabetic Nerve Pain: Symptoms And Treatment Uses For dexrazoxane Dexrazoxane is used to help prevent or lessen a toxic effect to your heart that is caused by certain medicines that are used to treat cancer. Dexrazoxane is also used to treat tissue damage caused by the leakage of certain medicines that are used to treat cancer . dexrazoxane is available only with your doctor's prescription. Before Using dexrazoxane In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dexrazoxane, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to dexrazoxane or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of dexrazoxane in the pediatric population. Safety and efficacy have not been established . Geriatric Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of dexrazoxane in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment of dosage in patients receiving dexrazoxane . Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking dexrazoxane, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using dexrazoxane with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Doxorubicin Doxorubicin Hydrochloride Liposome Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of dexrazoxane. Make sure you tell your doctor if you have any other medical problems, especially: Blood disorder or bleeding problem (e.g., leukopenia, neutropenia, or thrombocytopenia) May make this condition worse . Kidney disease The effects may be increased because of slower removal of the medicine from the body . Proper Use of dexrazoxane A nurse or other trained health professional will give you dexrazoxane. dexrazoxane is given through a needle placed into one of your veins . Dosing The dose of dexrazoxane will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dexrazoxane. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Precautions While Using dexrazoxane Using dexrazoxane while you are pregnant can harm your unborn baby. If you think you have become pregnant while using dexrazoxane, tell your doctor right away . Dexrazoxane can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding: If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin. Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters. Avoid situations where bruising or injury could occur . dexrazoxane Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Bluish color changes in skin color chest pain cold hands and feet cough or hoarseness difficult or labored breathing fever or chills lower back or side pain pain, redness, or swelling in arm or leg painful or difficult urination pale skin shortness of breath sneezing sore throat swelling of hands, ankles, feet, or lower legs tenderness tightness in chest troubled breathing unusual bleeding or bruising unusual tiredness or weakness wheezing Less common Black, tarry stools chest discomfort fast, irregular, or pounding heartbeat pain at place of injection ulcers, sores, or white spots in mouth Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Diarrhea difficulty having a bowel movement (stool) discouragement dizziness feeling sad or empty hair loss, thinning of hair headache irritability lack or loss of appetite loss of interest or pleasure muscle pain, spasms, cramps, or stiffness nausea stomach pain trouble concentrating trouble sleeping vomiting weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about dexrazoxane Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: miscellaneous uncategorized agents Consumer resources Dexrazoxane Other brands: Totect , Zinecard Professional resources Dexrazoxane Hydrochloride (AHFS Monograph) Dexrazoxane (FDA) Dexrazoxane (Wolters Kluwer) Related treatment guides Cardiomyopathy Prophylaxis Extravasation} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer Mylan Pharmaceuticals Inc. Drug Class Miscellaneous uncategorized agents Related Drugs Cardiomyopathy Prophylaxis dexrazoxane , Zinecard , More... Extravasation hyaluronidase , dexrazoxane , Amphadase , Hylenex , Totect , Vitrase , More... Dexrazoxane Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the dexrazoxane support group to connect with others who have similar interests.} } habit
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