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same October 31, 2017 By Jessica Kennedy, MHA Chief of Staff It s Halloween again. That means candy (good). Too much candy (bad). Funny costumes (good). Offensive costumes (bad). Every year we get calls about stigmatizing straightjacket costumes and haunted asylums. Which is a shame, because there are some people who might think that individuals living with mental health conditions are scary . But what s really scary isn t someone with depression, anxiety, bipolar, or psychosis it s the experiences we have every day with people who judge and hurt us. Here are six costumes that are scarier than mental patient. 1. The Unsupportive S.O. I just don t understand why you have to pay someone to talk about your problems. Can t you just solve them on your own? Why it s scary: Hey partner, aren t you supposed to be supportive, loving, and caring? I just opened up about what s going on with me (which is scary, by the way), and you re now actively trying to convince me not to get help. True story: My doctor asked me to tell my live-in partner that I was on a certain medication because some people experienced suicidal thoughts while using it. So I talked to my partner, just to get a long lecture about how I didn t need to be on meds. He demanded that I talk to other people and get more opinions before he d let me take my medication. And he made sure I knew that he was disappointed in me for taking meds every time I took a dose. You know what goes well with intense anxiety? Shame and disappointment. (Don t worry, he s an ex.) How to actually help : Support the people you love and care about. If they re doing something dangerous (like self-medicating with alcohol), there are other ways to approach the subject . Otherwise, just root for someone to succeed. Would you rather be right or happy? 2. The Infantilizing Parents Did you pay your rent this month? Did you make sure you schedule a doctor s appointment? How are you getting to work tomorrow? You know that breathing goes inhale, exhale, inhale, exhale, right? Why it s scary: To my well-meaning family: there are some things I need you to help me remember, like grandparents birthdays and my blood type, but I don t want to be treated like an unruly teenager when I m well into my adult years. And I know this comes from a place of love. I know that it is hard for you to watch me if I m struggling and that you have this instinct to swoop in and rescue me, but constantly questioning everything I do makes me feel like I m not a fully formed human. And that s demeaning. If you re my parents, and you don t believe in me, who can? How to actually help : Ask me how you can be supportive . Let me mess up a little bit and pick myself up off the ground. I m not asking you to watch me destroy myself, but I am asking you to trust me. 3. The Non-Accommodating Boss I know you have depression , but you missed too many days last month, and your projects are all behind schedule, so I m going to put you on a performance plan. Why it s scary: I know there are laws that are supposed to prevent discrimination against people with mental illness, but it s still happening all over the place . If I miss work because I have the flu, everyone wants me to get better and stay away from work. If I miss work because I am getting chemotherapy, everyone is rallying with love and support. But if I take time off work because I can t get out of bed (or my own head), I m still getting judged for it . Nobody believes us when we say we have an invisible illness like mental illness, headaches, or chronic fatigue until they experience it themselves. How to actually help : Believe me when I tell you I have a problem. Do you think I want to spend the day totally immobilized, curled up on my couch while wishing I could disappear, so no one could ever look at me or even know that I existed? Trust me, I d rather be at work than experiencing this! 4. The Only Way Is My Way BFF I don t know why you re doing all those things. I cured my depression through yogastrology. It s literally the only way. *sips organic apple kale smoothie* Why it s scary: Look, Ashleigh, everyone is happy that you re doing so well according to the 90,000 BuzzFeed articles on mental illness you ve shared on Facebook in the past year. And we really are supportive of your personal recovery journey. The thing that we want you to understand is that recovery looks different for everyone . It s one thing to talk up something that worked for you, recommend a specific therapist you liked, or publicly share your story to encourage others to get help. It s another to tell everyone else they have to get healthy your way and put down other methods of recovery. When you do that, you re not helping. You re making things worse. How to actually help : Be open minded. Respect our differences. Share your story and your experiences in a way that breaks down stigma and actively encourages other people to speak out. And when it s my turn to talk, please listen. 5. The Doctor Who Doesn t Ask I m going to listen to your lungs 20 times, but I m not going to ask about your emotional health, because then I d actually have to listen to you. Why it s scary: Doc, I get that you have a lot of patients to see, you re not paid enough, and asking about mental health issues makes visits longer. You re relying on me to bring up these issues because you re only going to see me for a few minutes, and I have been in my head all year. But you also must understand that bringing up mental health issues is scary and hard. I think I need help is getting caught in my throat. I wish you could help me bring it out. How to actually help: Ask me how I m doing and listen to me. I know that it s hard. Make yourself familiar with other local resources or support groups in the area. Get involved in advocacy to change the system. 6. The Ignorant Facebook Poster Back in my day, we didn t call it ADHD. We called it BEING A BOY. Repost this 12 times by copying and pasting it and not just hitting the share button so I know that you re really my friend. Why it s scary: I know you re trying to be funny or provocative for attention. That s the point of social media. And it s not fun to be the PC police jumping down your throat for a joke or a rant. But the thing is, when you belong to a group of people that gets put down a lot (whether it s because of your race, gender, or disability), it s really demoralizing to see people rant about you publicly all the time. To hear about having to lock crazies up. To be demeaned. How to actually help : Just think about what you re posting. Imagine what it would be like to be someone that had that feeling, and try to be just a little nicer. If you want to discuss over-diagnosis or population health, there are great forums and arenas for that. But doing it on my personal page when I m opening up about something sensitive to me doesn t help. To our loved ones who mean well, take some time this year to read more about how to support someone with a mental illness . Get informed about difference types of mental health conditions . Use person-centered language to avoid demeaning language . So sure, before you put on that straightjacket costume, think about how that makes people with mental illnesses feel. But Halloween is one day a year. There are 364 other opportunities (365 on leap years, obviously) to be a ghoul. And that s what s scary. Tags: halloween stigma holiday Awareness mental health awareness Mental Health America Blog premier


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for instance Ethinyl Estradiol and Levonorgestrel with Folate Generic Name: Ethinyl Estradiol and Levonorgestrel with Folate (ETH in il es tra DYE ole & LEE voe nor jes trel with FOE late) Brand Name: FaLessa Kit Overview Side Effects Interactions Reviews Q & A More Warning Do not smoke while taking ethinyl estradiol and levonorgestrel with folate. Cigarette smoking raises the chance of very bad heart problems. This chance is higher with age (older than 35 years of age) and with heavy smoking (15 or more cigarettes per day). Uses of Ethinyl Estradiol and Levonorgestrel with Folate: It is used to prevent pregnancy. It may be given to you for other reasons. Talk with the doctor. Slideshow Emergency Contraception Laid Bare - The 10 Biggest Myths Revealed What do I need to tell my doctor BEFORE I take Ethinyl Estradiol and Levonorgestrel with Folate? If you have an allergy to ethinyl estradiol, levonorgestrel, or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any of these health problems: Blood clots, blood clotting problem, breast cancer, diseased arteries in the brain, disease of a heart valve with problems, heart disease, chest pain caused by angina, heart attack, stroke, high blood pressure, high cholesterol, a pancreas problem (pancreatitis) due to high blood triglycerides, liver disease, liver tumor, very bad headache or migraine, diabetes that affects blood flow, or tumor where estrogen makes it grow. If you have had any of these health problems: Endometrial cancer, cancer of the cervix or vagina, or vaginal bleeding where the cause is not known. If you have surgery and need bedrest. If you are a heavy smoker (more than 15 cigarettes per day) and older than 35 years of age. If you turned yellow during pregnancy or with estrogen-based or hormone contraceptive use. If you are pregnant or may be pregnant. Do not take ethinyl estradiol and levonorgestrel with folate if you are pregnant. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take ethinyl estradiol and levonorgestrel with folate with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Ethinyl Estradiol and Levonorgestrel with Folate? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. This medicine may raise the chance of blood clots, a stroke, or a heart attack. Talk with the doctor. If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. Have your blood pressure checked often. Talk with your doctor. Have your blood work checked. Talk with your doctor. Be sure to have regular breast exams and gynecology check-ups. Your doctor will tell you how often to have these. You will also need to do breast self-exams as your doctor has told you. Talk with your doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take ethinyl estradiol and levonorgestrel with folate. Certain drugs, herbal products, or health problems could cause this medicine to not work as well. Be sure your doctor knows about all of your drugs and health problems. This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor. Do not use in children who have not had their first menstrual period. If you have any signs of pregnancy or if you have a positive pregnancy test, call your doctor right away. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Ethinyl Estradiol and Levonorgestrel with Folate) best taken? Use ethinyl estradiol and levonorgestrel with folate as ordered by your doctor. Read all information given to you. Follow all instructions closely. Follow how to use as you have been told by the doctor or read the package insert. Take this medicine at the same time of day. Take with or without food. Take with food if it causes an upset stomach. Do not skip doses, even if you do not have sex very often. If you throw up or have diarrhea, ethinyl estradiol and levonorgestrel with folate may not work as well to prevent pregnancy. Use an extra form of birth control, like condoms, until you check with your doctor. If you miss 2 periods in a row, take a pregnancy test before starting a new cycle. What do I do if I miss a dose? Take a missed dose as soon as you think about it and go back to your normal time. If a dose is missed, check the package insert or call the doctor to find out what to do. If using this medicine to prevent pregnancy, another form of birth control may need to be used for some time to prevent pregnancy. What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Coughing up blood. Shortness of breath. Chest pain or pressure. Very bad dizziness or passing out. Very upset stomach or throwing up. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Swelling, warmth, numbness, change of color, or pain in a leg or arm. Very bad headache. Low mood (depression). Feeling very tired or weak. 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Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Ethinyl Estradiol and Levonorgestrel with Folate? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about ethinyl estradiol and levonorgestrel with folate, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ethinyl estradiol and levonorgestrel with folate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using ethinyl estradiol and levonorgestrel with folate. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about ethinyl estradiol/folic acid/levonorgestrel Side Effects Drug Interactions Support Group En Español 5 Reviews Add your own review/rating Drug class: contraceptives Consumer resources Ethinyl estradiol, folic acid, and levonorgestrel Other brands: FaLessa Kit Related treatment guides Birth Control} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Ethinyl estradiol / folic acid / levonorgestrel Rating 5 User Reviews 6.0 /10 5 User Reviews 6.0 Rate it! Drug Class Contraceptives Related Drugs Birth Control medroxyprogesterone , Provera , Depo-Provera , norethindrone , Mirena , Nexplanon , Sprintec , levonorgestrel , NuvaRing , Ortho Tri-Cyclen , Yasmin , Yaz , TriNessa , Aviane , Lo Loestrin Fe , Apri , Alesse , Mononessa , Microgestin Fe 1 / 20 , Camila , Xulane , Seasonique , Lutera , Ortho Evra , Levora , More...} } could be


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each time Could New 'Brain Training' Program Help Prevent Dementia? really fizzling out

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the appropriate (*this news item will not be available after 02/15/2018) Friday, November 17, 2017 FRIDAY, Nov. 17, 2017 (HealthDay News) -- In what is being billed as a first, researchers report that healthy seniors who tried a new brain-training program were less likely to develop dementia down the road. "Everyone with a brain is at risk of dementia," noted study author Jerri Edwards. But "this is the first treatment ever shown in a clinical trial to make a difference." Edwards is a professor in the department of psychiatry and behavioral neurosciences at the University of South Florida. In essence, the program, called BrainHQ, tries to speed thinking by giving seniors the task of distinguishing between a series of ever-changing objects on a computer screen -- both in the center and periphery of their vision. Over time, the objects appear more quickly, and look more similar to one another. This makes the task increasingly difficult, with the aim being to boost the individual's ability to rapidly and accurately identify the objects at hand. Based on tracking more than 2,800 seniors, the team found that it appears to do just that. Over a 10-year period, the speed-of-thought-processing program lowered dementia risk by nearly 30 percent, the study team said, when compared with seniors who didn't have such training. In the study, funded by the U.S. National Institutes of Health, dementia-free seniors (all aged 65 and up) were divided into four groups. One group received no brain training of any kind. Over a six-week period, three other groups underwent at least 10 sessions of different types of brain training that lasted 60 to 75 minutes each. Some participants received additional training sessions beyond the initial six weeks. One group was offered strategic advice on how to improve their verbal memory skills, while a second group was offered strategies on improving their capacity to reason and problem-solve. The third group, however, underwent the computerized speed-of-thought-processing program. In the end, investigators determined that neither memory training nor reason training appeared to lower long-term dementia risk. But speed-of-thought-processing training appeared to cause dementia risk to fall by 29 percent over a decade. What's more, the more speed training sessions a senior got under his or her belt, the lower their dementia risk was going forward. In fact, among those seniors who completed 15 or more such sessions, the 10-year risk for dementia was pegged at just 5.9 percent. This compared with a roughly 10 percent risk seen among those who underwent either memory or reason training. Those who underwent no training of any kind had a nearly 11 percent risk. The program was developed by Karlene Ball of the University of Alabama, Birmingham, and Dan Roenker, of Western Kentucky University. The study was published Nov. 16 in the journal Alzheimer's & Dementia: Translational Research & Clinical Interventions . "It is important to understand that this intervention is not a game, that it's not just doing something on the computer," stressed Edwards. "It's a very specific training program that shows these benefits." Heather Snyder, senior director of medical and scientific operations with the Alzheimer's Association, said the organization believes that "this is the first time a cognitive training intervention has been shown to protect against cognitive impairment or dementia in a large, randomized, controlled trial." But Snyder added that, "these results need replication and confirmation in other populations with the same and similar tools." Adam Woods, assistant director of the Center for Cognitive Aging and Memory at the University of Florida, suggested the findings are "extremely exciting," while also noting that "not all cognitive trainings are created equal. "Some may interpret this as meaning that all cognitive training has the potential to slow the onset of dementia," he noted. "However, this study makes a clear case that a specific type of training demonstrated this effect. "Regardless," said Woods, "the fact that a computerized cognitive training program for speed of processing has the potential to impact dementia onset is an incredibly important finding that may provide hope to those concerned about developing dementia in the later years of life." SOURCES: Jerri Edwards, Ph.D., professor, department of psychiatry and behavioral neurosciences, University of South Florida, Tampa; Heather Snyder, Ph.D., senior director, medical and scientific operations, Alzheimer's Association; Adam Woods, Ph.D., assistant professor and assistant director, Center for Cognitive Aging and Memory, University of Florida, Gainesville; Nov. 16, 2017, Alzheimer's & Dementia: Translational Research & Clinical Interventions HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Dementia Seniors' Health Recent Health News that each one


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abruptly Capzasin-HP Generic Name: Capsaicin Cream, Gel, Liquid, and Lotion (kap SAY sin) Brand Name: Capsagel, Capsagel Extra Strength, Capsagel Maximum Strength, Capzasin, Capzasin-HP, ...show all 15 brand names. Capzasin-P, Castiva Warming, Theragen HP, Trixaicin HP, Zostrix, Zostrix Arthritis Pain Relief, Zostrix Diabetic Foot Pain, Zostrix Foot Pain Relief, Zostrix HP, Zostrix Sports Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A Uses of Capzasin-HP: It is used to ease muscle and joint aches and pain. It is used to help diabetic nerve pain. It may be given to you for other reasons. Talk with the doctor. Slideshow Top 11 Truths About Narcotic Painkiller Meds What do I need to tell my doctor BEFORE I take Capzasin-HP? If you have an allergy to Capzasin-HP (capsaicin cream, gel, liquid, and lotion) or any part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are using another drug like this one. This is not a list of all drugs or health problems that interact with Capzasin-HP. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Capzasin-HP? Tell all of your health care providers that you take Capzasin-HP. This includes your doctors, nurses, pharmacists, and dentists. Do not use coverings (bandages, dressings) unless told to do so by the doctor. This medicine may cause harm if swallowed. If this medicine is swallowed, call a doctor or poison control center right away. Avoid use of heat sources (such as sunlamps, tanning beds, heating pads, electric blankets, heat lamps, saunas, hot tubs, heated waterbeds). Avoid long, hot baths or sunbathing. Your temperature may rise and cause too much drug to pass into your body. Take Capzasin-HP off of the skin if very bad burning or itching happens. Use care when using on a large part of the skin. Talk with the doctor. Do not breathe in this medicine after it has dried. May cause nose or throat irritation. Some of these drugs may catch on fire. Do not use near an open flame or while smoking. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Capzasin-HP while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Capzasin-HP) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Do not take Capzasin-HP by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn). Clean affected part before use. Make sure to dry well. You may wear gloves when putting on. Do not put on irritated skin. Do not put on cuts, scrapes, or damaged skin. Do not bathe, shower, or swim right after putting on. Do not put on right after a shower or bath. If this medicine gets in the eyes, rinse with cool water. Wash your hands before and after use. Do not wash your hands after use if putting this on your hand. Put a thin layer on the affected skin and rub in gently. If hands are treated, do not wash your hands for 30 minutes after you put on Capzasin-HP. Do not touch your eyes, nose, mouth, genitals, irritated skin, or contact lenses until you wash your hands. What do I do if I miss a dose? If you use this medicine on a regular basis, put on a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not put on 2 doses or extra doses. Many times Capzasin-HP (capsaicin cream, gel, liquid, and lotion) is used on an as needed basis. Do not use more often than told by the doctor. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Very bad skin irritation. Very bad burning or burning that does not go away. What are some other side effects of Capzasin-HP? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Burning or stinging feeling. Most of the time, this will go away after a few days. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Capzasin-HP? Store at room temperature. Protect from heat or open flame. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take Capzasin-HP or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Capzasin-HP. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: December 6, 2017 Next Side Effects Print this page Add to My Med List More about Capzasin-HP (capsaicin topical) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 4 Reviews Add your own review/rating Drug class: miscellaneous topical agents Consumer resources Capzasin-HP Other brands: Zostrix , Trixaicin , Capsicum Oleoresin , Theragen HP , ... +14 more Professional resources Other Formulations Capzasin-P Capzasin Capzasin Back and Body Related treatment guides Diabetic Peripheral Neuropathy Osteoarthritis Pain Postherpetic Neuralgia} Drug Status Rx OTC Availability Rx and/or OTC B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Capzasin-HP Rating 4 User Reviews 5.8 /10 4 User Reviews 5.8 Rate it! Manufacturer Chattem, Inc. 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Photo :Aliskiren, Amlodipine, and Hydrochlorothiazide
employer Aliskiren, Amlodipine, and Hydrochlorothiazide Generic Name: Aliskiren, Amlodipine, and Hydrochlorothiazide (a lis KYE ren, am LOE di peen, & hye droe klor oh THYE a zide) Brand Name: Amturnide Overview Side Effects Professional Interactions Pregnancy More User Reviews Support Group Q & A Warning Do not take if you are pregnant. Use during pregnancy may cause birth defects or loss of the unborn baby. If you get pregnant or plan on getting pregnant while taking aliskiren, amlodipine, and hydrochlorothiazide, call your doctor right away. Uses of Aliskiren, Amlodipine, and Hydrochlorothiazide: It is used to treat high blood pressure. It may be given to you for other reasons. Talk with the doctor. Slideshow Ladies A Moment: 10 Health Screenings That All Women Need What do I need to tell my doctor BEFORE I take Aliskiren, Amlodipine, and Hydrochlorothiazide? If you have an allergy to aliskiren, amlodipine, hydrochlorothiazide, or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are taking any of these drugs: Cyclosporine, dofetilide, or itraconazole. If you are not able to pass urine. If you have kidney disease. If you have high blood sugar (diabetes) or kidney disease and are taking certain drugs for high blood pressure or your heart. Talk with your doctor. If you are breast-feeding. Do not breast-feed while you take aliskiren, amlodipine, and hydrochlorothiazide. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take aliskiren, amlodipine, and hydrochlorothiazide with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Aliskiren, Amlodipine, and Hydrochlorothiazide? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Avoid driving and doing other tasks or actions that call for you to be alert until you see how aliskiren, amlodipine, and hydrochlorothiazide affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs. If you have high blood sugar (diabetes), this medicine may sometimes raise blood sugar. Talk with your doctor about how to keep your blood sugar under control. Have your blood pressure checked often. Talk with your doctor. Have blood work checked as you have been told by the doctor. Talk with the doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take aliskiren, amlodipine, and hydrochlorothiazide. If you are taking a salt substitute that has potassium, potassium-sparing diuretics, or potassium, talk with your doctor. If you are on a low-salt or salt-free diet, talk with your doctor. It is rare, but worse chest pain and heart attack can happen after this medicine is first started or after the dose is raised. The risk may be greater in people who have very bad heart blood vessel disease. Talk with the doctor. This medicine can cause certain eye problems. If left untreated, this can lead to lasting eyesight loss. If eye problems happen, signs like change in eyesight or eye pain most often happen within hours to weeks of starting aliskiren, amlodipine, and hydrochlorothiazide. Call your doctor right away if you have these signs. Talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids. Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions. If you take cholestyramine or colestipol, talk with your pharmacist about how to take them with this medicine. Watch for gout attacks. If you have lupus, aliskiren, amlodipine, and hydrochlorothiazide can make your lupus active or get worse. Tell your doctor right away if you get any new or worse signs. Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss. Tell your doctor if you have too much sweat, fluid loss, throwing up, or loose stools. This may lead to low blood pressure. If you are taking lithium, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with this medicine. If you are 65 or older, use aliskiren, amlodipine, and hydrochlorothiazide with care. You could have more side effects. How is this medicine (Aliskiren, Amlodipine, and Hydrochlorothiazide) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Keep taking aliskiren, amlodipine, and hydrochlorothiazide as you have been told by your doctor or other health care provider, even if you feel well. This medicine may cause you to pass urine more often. To keep from having sleep problems, try to take before 6 pm. Take this medicine at the same time of day. To gain the most benefit, do not miss doses. Take with or without food. Always take with food or always take on an empty stomach. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor. What do I do if I miss a dose? Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit. Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up. Chest pain that is new or worse. Trouble swallowing. Swelling in the arms or legs. Stiff muscles, shakiness, or muscle movements that are not normal. A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. What are some other side effects of Aliskiren, Amlodipine, and Hydrochlorothiazide? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dizziness. Cough. Loose stools (diarrhea). Headache. Sore throat. Stuffy nose. Runny nose. Feeling tired or weak. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Aliskiren, Amlodipine, and Hydrochlorothiazide? Store in the original container at room temperature. Protect from heat. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about aliskiren, amlodipine, and hydrochlorothiazide, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about aliskiren, amlodipine, and hydrochlorothiazide. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using aliskiren, amlodipine, and hydrochlorothiazide. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about aliskiren/amlodipine/hydrochlorothiazide Side Effects During Pregnancy Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: miscellaneous antihypertensive combinations Consumer resources Aliskiren, amlodipine, and hydrochlorothiazide (Advanced Reading) Other brands: Amturnide Professional resources Aliskiren, Amlodipine, and Hydrochlorothiazide (Wolters Kluwer) Related treatment guides High Blood Pressure} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA WADA Class Anti-Doping Classification Aliskiren / amlodipine / hydrochlorothiazide Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Drug Class Miscellaneous antihypertensive combinations Related Drugs High Blood Pressure amlodipine , lisinopril , hydrochlorothiazide , furosemide , losartan , metoprolol , atenolol , Lasix , Norvasc , valsartan , enalapril , Diovan , Cozaar , Benicar , Toprol-XL , Bystolic , irbesartan , Lopressor , hydrochlorothiazide / lisinopril , hydrochlorothiazide / triamterene , Maxzide , Zestril , Dyazide , More... Related: High Blood Pressure (Hypertension)} } fits


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doing some DHS Tar Shampoo you haven't any

for this reason DHS Tar Shampoo a number of
 
Photo :DHS Tar Shampoo
what will DHS Tar Shampoo Generic Name: coal tar topical (KOL TAR TOP ik al) Brand Name: Balnetar, Denorex Extra Strength, DHS Tar Shampoo, Elta Tar, Ionil T, MG217 Medicated Tar, Neutrogena T/Gel, Oxipor VHC, Psoriasin, Scytera, Tarsum, Tegrin Medicated, Theraplex T Overview Side Effects Interactions Breastfeeding Reviews More Support Group Q & A Pricing & Coupons What is coal tar? Coal tar is a by-product of coal processing. Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms. Coal tar may also be used for purposes not listed in this medication guide. Slideshow Psoriasis: Treatment Options to Manage Your Symptoms and Skin What is the most important information I should know about coal tar? Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. What should I discuss with my health care provider before using coal tar? You should not use this medicine if you are allergic to coal tar. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially: if you are allergic to any drugs; or if you are receiving ultraviolet radiation treatment for your psoriasis. Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients. Ask a doctor before using this medicine if you are pregnant or breast-feeding. Do not allow a young child to use this medicine without adult supervision. How should I use coal tar? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Apply coal tar cream, lotion, ointment, or solution according to the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day. To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall. Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Coal tar shampoo may discolor blond or colored hair. This effect is usually temporary. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice. Some forms of coal tar can stain fabric or other surfaces. Call your doctor if your symptoms do not improve, or if they get worse while using coal tar topical. Store at room temperature away from moisture and heat. Keep the medicine tightly closed when not in use. What happens if I miss a dose? Since coal tar topical is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? An overdose of coal tar topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. What should I avoid while using coal tar? Do not use coal tar together with other psoriasis medications unless your doctor tells you to. Avoid getting coal tar topical in your eyes. If this does occur, rinse with water. Do not use coal tar to treat the skin of your groin or rectal area. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Coal tar side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: severe stinging, burning, swelling, or other irritation of the treated skin. Common side effects may include mild skin irritation or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect coal tar? It is not likely that other drugs you take orally or inject will have an effect on topically applied coal tar. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Next Side Effects Print this page Add to My Med List More about DHS Tar Shampoo (coal tar topical) Side Effects Breastfeeding Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: miscellaneous topical agents Consumer resources DHS Tar Topical (Advanced Reading) Other brands: Psoriasin , Estar , Medotar , Scytera , ... +17 more Professional resources Related treatment guides Dermatitis Psoriasis Seborrheic Dermatitis Where can I get more information? Your pharmacist can provide more information about coal tar topical. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 1.07. Date modified: December 03, 2017 Last reviewed: March 15, 2017 Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Miscellaneous topical agents Related Drugs Seborrheic Dermatitis prednisone , hydrocortisone topical , ketoconazole topical , dexamethasone , Decadron , Deltasone , ciclopirox topical , More... Psoriasis Humira , methotrexate , cyclosporine , Remicade , adalimumab , infliximab , Stelara , More... Dermatitis fluticasone topical , triamcinolone , hydrocortisone topical , prednisolone , clobetasol topical , betamethasone topical , doxepin topical , More... DHS Tar Shampoo Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the DHS Tar Shampoo support group to connect with others who have similar interests. tense


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coming back from dextromethorphan and promethazine family member

a terribly dextromethorphan and promethazine exercise session
 
Photo :dextromethorphan and promethazine
fill up dextromethorphan and promethazine Generic Name: dextromethorphan and promethazine (dex troe me THOR fan and pro METH a zeen) Brand Name: Promethazine with Dextromethorphan, Promethazine with DM, Phenergan with Dextromethorphan, Promethazine DM Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons What is dextromethorphan and promethazine? Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex. Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. The combination of dextromethorphan and promethazine used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema. Dextromethorphan and promethazine may also be used for purposes other than those listed in this medication guide. Slideshow Over the Counter Cold Remedies - Which One is Right For You? What is the most important information I should know about dextromethorphan? Call your doctor immediately if you experience uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use dextromethorphan and promethazine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan and promethazine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema. What should I discuss with my healthcare provider before taking dextromethorphan and promethazine? Do not use dextromethorphan and promethazine if you have asthma or other lung disease. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough or cold medicine before the MAO inhibitor has cleared from your body. Before taking dextromethorphan and promethazine, tell your doctor if you are allergic to any drugs, or if you have emphysema or chronic bronchitis. You may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment. Before taking dextromethorphan and promethazine, tell your doctor if you have: epilepsy or another seizure disorder; emphysema or chronic bronchitis; sleep apnea (breathing stops during sleep); glaucoma; a stomach ulcer or digestive obstruction; bone marrow disorder; problems with urination; high blood pressure or heart disease; or liver disease. If you have any of these conditions, you may not be able to use dextromethorphan and promethazine, or you may need a dosage adjustment or special tests during treatment. FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medication passes into breast milk or if it could harm an unborn baby. Do not use dextromethorphan and promethazine without telling your doctor if you are breast-feeding a baby. How should I take dextromethorphan and promethazine? Take this medication exactly as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Follow the directions on your prescription label. Cough or cold medicine is usually taken only for a short time until your symptoms clear up. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cough medicine within the past few days. Store dextromethorphan and promethazine at room temperature, away from heat, light, and moisture. What happens if I miss a dose? Since cough and cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a dextromethorphan and promethazine overdose may include feeling restless or nervous, severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting. What should I avoid while taking dextromethorphan and promethazine? This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of dextromethorphan and promethazine. Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with cough medicine can increase your risk of unpleasant side effects. Avoid using other drugs that make you sleepy (such as cold medicine, sleeping pills, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. Dextromethorphan is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of this medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan. Dextromethorphan and promethazine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using dextromethorphan and promethazine and call your doctor at once if you have any of these serious side effects: uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; tremors, twitching, or uncontrolled muscle movements in your face, arms, or legs. severe dizziness, anxiety, restless feeling, or nervousness; hallucinations (seeing or hearing things); confusion, hallucinations; or slow, shallow breathing, weak pulse; nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or fever, muscle stiffness, confusion, fast or uneven heartbeat, sweating, fainting. Keep taking dextromethorphan and promethazine and talk with your doctor if you have any of these less serious side effects: dizziness, drowsiness, sleepiness, or confusion; blurred vision, dry mouth; ringing in your ears; nausea or vomiting; or increased sensitivity to sunlight. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Dextromethorphan and promethazine dosing information Usual Adult Dose for Allergic Rhinitis: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Usual Adult Dose for Cold Symptoms: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Usual Adult Dose for Cough: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Usual Pediatric Dose for Allergic Rhinitis: Less than 2 years: Contraindicated 2 years to less than 6 years: 1.25 to 2.5 mL orally every 4 to 6 hours Maximum dose: 10 mL in 24 hours (promethazine 12.5 mg; dextromethorphan 30 mg) 6 years to less than 12 years: 2.5 to 5 mL orally every 4 to 6 hours Maximum dose: 20 mL in 24 hours (promethazine 25 mg; dextromethorphan 60 mg) 12 years to 18 years: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. -Extra caution is advised with use of promethazine in children as respiratory depression is strongly associated with use; however, its occurrence is not directly related to individualized weight base dosing. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Usual Pediatric Dose for Cold Symptoms: Less than 2 years: Contraindicated 2 years to less than 6 years: 1.25 to 2.5 mL orally every 4 to 6 hours Maximum dose: 10 mL in 24 hours (promethazine 12.5 mg; dextromethorphan 30 mg) 6 years to less than 12 years: 2.5 to 5 mL orally every 4 to 6 hours Maximum dose: 20 mL in 24 hours (promethazine 25 mg; dextromethorphan 60 mg) 12 years to 18 years: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. -Extra caution is advised with use of promethazine in children as respiratory depression is strongly associated with use; however, its occurrence is not directly related to individualized weight base dosing. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Usual Pediatric Dose for Cough: Less than 2 years: Contraindicated 2 years to less than 6 years: 1.25 to 2.5 mL orally every 4 to 6 hours Maximum dose: 10 mL in 24 hours (promethazine 12.5 mg; dextromethorphan 30 mg) 6 years to less than 12 years: 2.5 to 5 mL orally every 4 to 6 hours Maximum dose: 20 mL in 24 hours (promethazine 25 mg; dextromethorphan 60 mg) 12 years to 18 years: 5 mL orally every 4 to 6 hours Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: -Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg. -Extra caution is advised with use of promethazine in children as respiratory depression is strongly associated with use; however, its occurrence is not directly related to individualized weight base dosing. Use: For the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. What other drugs will affect dextromethorphan and promethazine? Before taking dextromethorphan and promethazine, tell your doctor if you are using any of the following drugs: celecoxib (Celebrex); cinacalcet (Sensipar); darifenacin (Enablex); imatinib (Gleevec); quinidine (Quinaglute, Quinidex); ranolazine (Ranexa) ritonavir (Norvir); sibutramine (Meridia); terbinafine (Lamisil); medicines to treat high blood pressure; antidepressant medications such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others. sedatives or anxiety medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion); phenobarbital (Luminal), amobarbital (Amytal) and secobarbital (Seconal); or atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), methscopolamine (Pamine), and scopolamine (Transderm-Scop). If you are using any of these drugs, you may not be able to use dextromethorphan and promethazine, or you may need dosage adjustments or special tests during treatment. There may be other drugs not listed that can affect dextromethorphan and promethazine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Next Side Effects Print this page Add to My Med List More about dextromethorphan/promethazine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 8 Reviews Add your own review/rating Drug class: upper respiratory combinations Consumer resources Promethazine and Dextromethorphan Other brands: Promethazine with Dextromethorphan , Promethazine with DM Professional resources Dextromethorphan and Promethazine Syrup (FDA) Promethazine and Dextromethorphan (FDA) Promethazine and Dextromethorphan (Wolters Kluwer) Related treatment guides Allergic Rhinitis Cold Symptoms Cough Where can I get more information? Your pharmacist has information about dextromethorphan and promethazine written for health professionals that you may read. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 2.07. Date modified: December 03, 2017 Last reviewed: December 15, 2010} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Upper respiratory combinations Related Drugs Cough benzonatate , acetaminophen / hydrocodone , diphenhydramine , Benadryl , Mucinex , guaifenesin , Dilaudid , Promethazine DM , More... Cold Symptoms diphenhydramine , Benadryl , Promethazine DM , chlorpheniramine , echinacea , Tussionex Pennkinetic , Banophen , Benadryl Allergy , More... Allergic Rhinitis prednisone , Zyrtec , promethazine , fluticasone nasal , loratadine , cetirizine , Flonase , triamcinolone , More... Dextromethorphan / promethazine Rating 8 User Reviews 7.1 /10 8 User Reviews 7.1 Rate it! Help and Support Looking for answers? Ask a question or go join the dextromethorphan / promethazine support group to connect with others who have similar interests.} } a really


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one hundred and fortieth Dextromethorphan and Promethazine Syrup Generic Name: promethazine hydrochloride and dextromethorphan hydrobromide Dosage Form: syrup Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Dextromethorphan and Promethazine Syrup Description Each 5 mL (one teaspoonful), for oral administration contains: dextromethorphan hydrobromide 15 mg; promethazine hydrochloride 6.25 mg. Alcohol 8%(v/v). Inactive Ingredients: anhydrous citric acid, ascorbic acid, edetate disodium, FD&C yellow No. 6, methylparaben, natural and artificial lemon mint flavor, propylene glycol, propylparaben, purified water, sodium benzoate, sodium citrate anhydrous, saccharin sodium, and sucrose. Dextromethorphan hydrobromide is a salt of the methyl ether of the dextrorotatory isomer of levorphanol, a narcotic analgesic. It is chemically designated as 3-methoxy-17-methyl-9α, 13α, 14α-morphinan hydrobromide monohydrate. Dextromethorphan hydrobromide occurs as white crystals sparingly soluble in water and freely soluble in alcohol. It has a molecular weight of 370.32, a molecular formula of C 18 H 25 NO HBr H 2 O, and the following structural formula: Promethazine is a racemic compound. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as 10 H -Phenothiazine-10-ethanamine, N,N, α-trimethyl-, monohydrochloride. Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol. It has a molecular weight of 320.88, a molecular formula of C 17 H 20 N 2 S HCl, and the following structural formula: Slideshow COPD: Could You Be At Risk? Dextromethorphan and Promethazine Syrup - Clinical Pharmacology Dextromethorphan: Dextromethorphan is an antitussive agent and, unlike the isomeric levorphanol, it has no analgesic or addictive properties. The drug acts centrally and elevates the threshold for coughing. It is about equal to codeine in depressing the cough reflex. In therapeutic dosage dextromethorphan does not inhibit ciliary activity. Dextromethorphan is rapidly absorbed from the gastrointestinal tract and exerts its effect in 15 to 30 minutes. The duration of action after oral administration is approximately three to six hours. Dextromethorphan is metabolized primarily by liver enzymes undergoing O-demethylation, N-demethylation, and partial conjugation with glucuronic acid and sulfate. In humans, (+)-3-hydroxy-N-methyl-morphinan, (+)-3-hydroxymorphinan, and traces of unmetabolized drug were found in urine after oral administration. Promethazine: Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. It is thought that this configuration is responsible for its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. Promethazine is an H 1 receptor blocking agent. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects. Promethazine is well absorbed from the gastrointestinal tract. Clinical effects are apparent within 20 minutes after oral administration and generally last four to six hours, although they may persist as long as 12 hours. Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of promethazine and N-demethylpromethazine are the predominant metabolites appearing in the urine. Indications and Usage for Dextromethorphan and Promethazine Syrup Promethazine hydrochloride and dextromethorphan hydrobromide syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. Contraindications Dextromethorphan should not be used in patients receiving a monoamine oxidase inhibitor (MAOI) (see PRECAUTIONS, Drug Interactions ). Promethazine is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms, including asthma. BOXED WARNING WARNINGS PROMETHAZINE HYDROCHLORIDE SHOULD NOT BE USED IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. POSTMARKETING CASES OF RESPIRATORY DEPRESSION, INCLUDING FATALITIES, HAVE BEEN REPORTED WITH USE OF PROMETHAZINE HYDROCHLORIDE IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE. A WIDE RANGE OF WEIGHT-BASED DOSES OF PROMETHAZINE HYDROCHLORIDE HAVE RESULTED IN RESPIRATORY DEPRESSION IN THESE PATIENTS. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER. IT IS RECOMMENDED THAT THE LOWEST EFFECTIVE DOSE OF PROMETHAZINE HYDROCHLORIDE BE USED IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER AND CONCOMITANT ADMINISTRATION OF OTHER DRUGS WITH RESPIRATORY DEPRESSANT EFFECTS BE AVOIDED. Dextromethorphan: Administration of dextromethorphan may be accompanied by histamine release and should be used with caution in atopic children. Promethazine: CNS Depression Promethazine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. The impairment may be amplified by concomitant use of other central-nervous-system depressants such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore such agents should either be eliminated or given in reduced dosage in the presence of promethazine HCl (see PRECAUTIONS-Information for Patients and Drug Interactions ). Respiratory Depression Promethazine may lead to potentially fatal respiratory depression. Use of promethazine in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine may lower seizure threshold. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. Bone-Marrow Depression Promethazine should be used with caution in patients with bone-marrow depression. Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow-toxic agents. Neuroleptic Malignant Syndrome A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with promethazine HCl alone or in combination with antipsychotic drugs. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias). The diagnostic evaluation of patients with this syndrome is complicated. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g. pneumonia, systemic infection, etc.) and untreated or inadequately treated extrapyramidal signs and symptoms (EPS). Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever and primary central nervous system (CNS) pathology. The management of NMS should include 1) immediate discontinuation of promethazine HCl, antipsychotic drugs, if any, and other drugs not essential to concurrent therapy, 2) intensive symptomatic treatment and medical monitoring, and 3) treatment of any concomitant serious medical problems for which specific treatments are available. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. Since recurrences of NMS have been reported with phenothiazines, the reintroduction of promethazine HCl should be carefully considered. Use In Pediatric Patients PROMETHAZINE PRODUCTS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE PRODUCTS TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. RESPIRATORY DEPRESSION AND APNEA, SOMETIMES ASSOCIATED WITH DEATH, ARE STRONGLY ASSOCIATED WITH PROMETHAZINE PRODUCTS AND ARE NOT DIRECTLY RELATED TO INDIVIDUALIZED WEIGHT-BASED DOSING, WHICH MIGHT OTHERWISE PERMIT SAFE ADMINISTRATION. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. THE EXTRAPYRAMIDAL SYMPTOMS WHICH CAN OCCUR SECONDARY TO PROMETHAZINE HYDROCHLORIDE ADMINISTRATION MAY BE CONFUSED WITH THE CNS SIGNS OF UNDIAGNOSED PRIMARY DISEASE, e.g., ENCEPHALOPATHY OR REYE S SYNDROME. THE USE OF PROMETHAZINE PRODUCTS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE S SYNDROME OR OTHER HEPATIC DISEASES. Excessively large dosages of antihistamines, including promethazine hydrochloride, in pediatric patients may cause sudden death (see OVERDOSAGE ). Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. In pediatric patients who are acutely ill associated with dehydration, there is an increased susceptibility to dystonias with the use of promethazine HCl. Other Consideration: Administration of promethazine has been associated with reported cholestatic jaundice. Precautions Animal reproduction studies have not been conducted with the drug combination promethazine and dextromethorphan. It is not known whether this drug combination can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Promethazine and dextromethorphan should be given to a pregnant woman only if clearly needed. General Dextromethorphan should be used with caution in sedated patients, in the debilitated, and in patients confined to the supine position. Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. Promethazine should be used cautiously in persons with cardiovascular disease or with impairment of liver function. Information for Patients Promethazine and dextromethorphan may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Ambulatory patients should be told to avoid engaging in such activities until it is known that they do not become drowsy or dizzy from promethazine and dextromethorphan therapy. Children should be supervised to avoid potential harm in bike riding or in other hazardous activities. The concomitant use of alcohol or other central nervous system depressants, including narcotic analgesics, sedatives, hypnotics, and tranquilizers, may have an additive effect and should be avoided or their dosage reduced. Patients should be advised to report any involuntary muscle movements. Avoid prolonged exposure to the sun. Drug Interactions Dextromethorphan: Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of monoamine oxidase (MAO) inhibitors and products containing dextromethorphan. Thus, concomitant administration of promethazine with dextromethorphan and MAO inhibitors should be avoided (see CONTRAINDICATIONS ). Promethazine: CNS Depressants - Promethazine may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. When given concomitantly with promethazine, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Dosage must be individualized. Excessive amounts of promethazine HCl relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain. Epinephrine - Because of the potential for promethazine to reverse epinephrine s vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethezine overdose. Anticholinergics - Concomitant use of other agents with anticholinergic properties should be undertaken with caution. Monoamine oxidase inhibitors (MAOI) - Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. Drug/Or Laboratory Test Interactions The following laboratory tests may be affected in patients who are receiving therapy with promethazine hydrochloride: Pregnancy Tests: Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. Glucose Tolerance Test: An increase in blood glucose has been reported in patients receiving promethazine. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine or of dextromethorphan. There are no animal or human data concerning the carcinogenicity, mutagenicity, or impairment of fertility with these drugs. Promethazine was nonmutagenic in the Salmonella test system of Ames. Pregnancy Teratogenic Effects Pregnancy category C : Teratogenic effects have not been demonstrated in rat-feeding studies at doses of 6.25 and 12.5 mg/kg of promethazine HCl. These doses are from approximately 2.1 to 4.2 times the maximum recommended total daily dose of promethazine for a 50-kg subject, depending upon the indication for which the drug is prescribed. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. There are no adequate and well-controlled studies of promethazine in pregnant women. Promethazine and dextromethorphan should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Nonteratogenic Effects Promethazine administered to a pregnant woman within two weeks of delivery may inhibit platelet aggregation in the newborn. Labor and Delivery Limited data suggest that use of promethazine HCl during labor and delivery does not have an appreciable effect on the duration of labor or delivery and does not increase the risk of need for intervention in the newborn. The effect on later growth and development of the newborn is unknown. See also Nonteratogenic Effects . Nursing Mothers It is not known whether promethazine or dextromethorphan is excreted in human milk. Caution should be exercised when promethazine and dextromethorphan is administered to a nursing woman. Pediatric Use PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE SYRUP IS CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (see WARNINGS Black Box Warning and Use in Pediatric Patients ). Promethazine hydrochloride and dextromethorphan hydrobromide syrup should be used with caution in pediatric patients 2 years of age and older (see WARNINGS Use in Pediatric Patients ). Geriatric Use Clinical studies of promethazine hydrochloride and dextromethorphan hydrobromide syrup did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of promethazine hydrochloride and dextromethorphan hydrobromide syrup and observed closely. Adverse Reactions Dextromethorphan: Dextromethorphan hydrobromide occasionally causes slight drowsiness, dizziness, and gastrointestinal disturbances. Promethazine:Central Nervous System - Drowsiness is the most prominent CNS effect of this drug. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Hallucinations have also been reported. Cardiovascular - Increased or decreased blood pressure, tachycardia, bradycardia, faintness. Dermatologic - Dermatitis, photosensitivity, urticaria. Hematologic - Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. Gastrointestinal - Dry mouth, nausea, vomiting, jaundice. Respiratory - Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal) (see WARNINGS-Promethazine; Respiratory Depression ). Other - Angioneurotic edema. Neuroleptic malignant syndrome (potentially fatal) has also been reported (see WARNINGS-Promethazine; Neuroleptic Malignant Syndrome ). Paradoxical Reactions - Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HCl. Consideration should be given to the discontinuation of promethazine HCl and to the use of other drugs if these reactions occur. Respiratory depression, nightmares, delirium, and agitated behavior have also been reported in some of these patients. Drug Abuse and Dependence According to the WHO Expert Committee on Drug Dependence, dextromethorphan could produce very slight psychic dependence but no physical dependence. Overdosage Dextromethorphan: Dextromethorphan may produce central excitement and mental confusion. Very high doses may produce respiratory depression. One case of toxic psychosis (hyperactivity, marked visual and auditory hallucinations) after ingestion of a single dose of 20 tablets (300 mg) of dextromethorphan has been reported. Promethazine: Signs and symptoms of overdosage with promethazine HCl range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). Stimulation may be evident, especially in children and geriatric patients. Convulsions may rarely occur. A paradoxical reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Atropine-like signs and symptoms dry mouth, fixed dilated pupils, flushing, as well as gastrointestinal symptoms, may occur. Treatment: The treatment of overdosage with promethazine and dextromethorphan is essentially symptomatic and supportive. Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG need to be monitored. Activated charcoal orally or by lavage may be given, or sodium or magnesium sulfate orally as a cathartic. Attention should be given to the reestablishment of adequate respiratory exchange through provision of a patient airway and institution of assisted or controlled ventilation. Diazepam may be used to control convulsions. Acidosis and electrolyte losses should be corrected. The antidotal efficacy of narcotic antagonists to dextromethorphan has not been established; note that any of the depressant effects of promethazine are not reversed by naloxone. Avoid analeptics, which may cause convulsions. Severe hypotension usually responds to the administration of norepinephrine or phenylephrine. EPINEPHRINE SHOULD NOT BE USED, since its use in a patient with partial adrenergic blockage may further lower the blood pressure. Limited experience with dialysis indicates that it is not helpful. Dextromethorphan and Promethazine Syrup Dosage and Administration Promethazine hydrochloride and dextromethorphan hydrobromide syrup is contraindicated for children under 2 years of age (see WARNINGS Black Box Warning and Use in Pediatric Patients ). The average effective dose is given in the following table: Adults 1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 30 mL in 24 hours. Children 6 years to under 12 years to 1 teaspoonful (2.5 to 5 mL) every 4 to 6 hours, not to exceed 20 mL in 24 hours. Children 2 years to under 6 years to teaspoonful (1.25 to 2.5 mL) every 4 to 6 hours, not to exceed 10 mL in 24 hours. How is Dextromethorphan and Promethazine Syrup Supplied This preparation is a yellow to amber colored lemon-mint flavored syrup, containing promethazine hydrochloride 6.25 mg/5 mL, dextromethorphan hydrobromide 15 mg/5 mL and alcohol 7 percent, and is available in 16 fl. oz. (473 mL) bottles, (NDC 27808-057-01) Keep tightly closed. Protect from light. Store at 25 C (77 F); excursions permitted from 15 to 30 C (59 to 86 F). [see USP Controlled Room Temperature]. Dispense in a tight, light-resistant container as defined in the USP. PACKAGE LABEL.PRINCIPAL DISPLAY PANEL 6.25 mg and 15 mg per 5 mL Manufactured By: Tris Pharma Inc. Monmouth Junction, NJ 08852 www.trispharma.com LB8077 Rev 00 03/12 PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE promethazine hydrochloride and dextromethorphan hydrobromide syrup Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:27808-057 Route of Administration ORAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength PROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) PROMETHAZINE HYDROCHLORIDE 6.25 mg in 5 mL DEXTROMETHORPHAN HYDROBROMIDE (DEXTROMETHORPHAN) DEXTROMETHORPHAN HYDROBROMIDE 15 mg in 5 mL Inactive Ingredients Ingredient Name Strength ALCOHOL ANHYDROUS CITRIC ACID ASCORBIC ACID EDETATE DISODIUM FD&C YELLOW NO. 6 METHYLPARABEN PROPYLENE GLYCOL PROPYLPARABEN SODIUM BENZOATE SODIUM CITRATE SACCHARIN SODIUM SUCROSE WATER Product Characteristics Color YELLOW (amber) Score Shape Size Flavor LEMON (mint) Imprint Code Contains Packaging # Item Code Package Description 1 NDC:27808-057-01 473 mL in 1 BOTTLE, PLASTIC Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date ANDA ANDA091687 01/31/2014 Labeler - Tris Pharma Inc (947472119) Revised: 08/2016 Tris Pharma Inc Next Interactions Print this page Add to My Med List More about dextromethorphan/promethazine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 8 Reviews Add your own review/rating Drug class: upper respiratory combinations Consumer resources Dextromethorphan and promethazine Promethazine and Dextromethorphan Professional resources Promethazine and Dextromethorphan (FDA) Promethazine and Dextromethorphan (Wolters Kluwer) Other brands: Promethazine DM Related treatment guides Allergic Rhinitis Cold Symptoms Cough} FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Upper respiratory combinations Related Drugs upper respiratory combinations Promethazine DM , Cheratussin AC , Mucinex DM Cough benzonatate , acetaminophen / hydrocodone , diphenhydramine , Benadryl , Mucinex , guaifenesin , Dilaudid , Promethazine DM , More... Cold Symptoms diphenhydramine , Benadryl , Promethazine DM , chlorpheniramine , echinacea , Tussionex Pennkinetic , Banophen , Benadryl Allergy , More... Allergic Rhinitis prednisone , Zyrtec , promethazine , fluticasone nasal , loratadine , cetirizine , Flonase , triamcinolone , More... Dextromethorphan / promethazine Rating 8 User Reviews 7.1 /10 8 User Reviews 7.1 Rate it!} } considered necessary


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