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that you can think of [2:<12 years old). One PK study was conducted in 9 full-term neonates (mean age: 7 days and mean gestational age: 38.8 weeks). The study results show that neonates had comparable plasma lidocaine and prilocaine concentrations and blood methemoglobin concentrations as those found in previous pediatric PK studies and clinical trials. There was a tendency towards an increase in methemoglobin formation. However, due to assay limitations and very little amount of blood that could be collected from neonates, large variations in the above reported concentrations were found. Special Populations: No specific PK studies were conducted. The half-life may be increased in cardiac or hepatic dysfunction. Prilocaine's half-life also may be increased in hepatic or renal dysfunction since both of these organs are involved in prilocaine metabolism. Clinical Studies Lidocaine and prilocaine cream application in adults prior to IV cannulation or venipuncture was studied in 200 patients in four clinical studies in Europe. Application for at least 1 hour provided significantly more dermal analgesia than placebo cream or ethyl chloride. Lidocaine and prilocaine cream was comparable to subcutaneous lidocaine, but was less efficacious than intradermal lidocaine. Most patients found lidocaine and prilocaine cream treatment preferable to lidocaine infiltration or ethyl chloride spray. Lidocaine and prilocaine cream was compared with 0.5% lidocaine infiltration prior to skin graft harvesting in one open label study in 80 adult patients in England. Application of lidocaine and prilocaine cream for 2 to 5 hours provided dermal analgesia comparable to lidocaine infiltration. Lidocaine and prilocaine cream application in children was studied in seven non-US studies (320 patients) and one US study (100 patients). In controlled studies, application of lidocaine and prilocaine cream for at least 1 hour with or without presurgical medication prior to needle insertion provided significantly more pain reduction than placebo. In children under the age of seven years, lidocaine and prilocaine cream was less effective than in older children or adults. Lidocaine and prilocaine cream was compared with placebo in the laser treatment of facial port-wine stains in 72 pediatric patients (ages 5 to 16). Lidocaine and prilocaine cream was effective in providing pain relief during laser treatment. Lidocaine and prilocaine cream alone was compared with lidocaine and prilocaine cream followed by lidocaine infiltration and lidocaine infiltration alone prior to cryotherapy for the removal of male genital warts. The data from 121 patients demonstrated that lidocaine and prilocaine cream was not effective as a sole anesthetic agent in managing the pain from the surgical procedure. The administration of lidocaine and prilocaine cream prior to lidocaine infiltration provided significant relief of discomfort associated with local anesthetic infiltration and thus was effective in the overall reduction of pain from the procedure only when used in conjunction with local anesthetic infiltration of lidocaine. Lidocaine and prilocaine cream was studied in 105 full term neonates (gestational age: 37 weeks) for blood drawing and circumcision procedures. When considering the use of lidocaine and prilocaine cream in neonates, the primary concerns are the systemic absorption of the active ingredients and the subsequent formation of methemoglobin. In clinical studies performed in neonates, the plasma levels of lidocaine, prilocaine, and methemoglobin were not reported in a range expected to cause clinical symptoms. Local dermal effects associated with lidocaine and prilocaine cream application in these studies on intact skin included paleness, redness and edema and were transient in nature (see ADVERSE REACTIONS ). The application of lidocaine and prilocaine cream on genital mucous membranes for minor, superficial surgical procedures (eg, removal of condylomata acuminata) was studied in 80 patients in a placebo-controlled clinical trial (60 patients received lidocaine and prilocaine cream and 20 patients received placebo). Lidocaine and prilocaine cream (5 to 10 g) applied between 1 and 75 minutes before surgery, with a median time of 15 minutes, provided effective local anesthesia for minor superficial surgical procedures. The greatest extent of analgesia, as measured by VAS scores, was attained after 5 to 15 minutes' application. The application of lidocaine and prilocaine cream to genital mucous membranes as pretreatment for local anesthetic infiltration was studied in a double-blind, placebo-controlled study in 44 female patients (21 patients received lidocaine and prilocaine cream and 23 patients received placebo) scheduled for infiltration prior to a surgical procedure of the external vulva or genital mucosa. Lidocaine and prilocaine cream applied to the genital mucous membranes for 5 to 10 minutes resulted in adequate topical anesthesia for local anesthetic injection. Individualization of Dose: The dose of lidocaine and prilocaine cream that provides effective analgesia depends on the duration of the application over the treated area. All pharmacokinetic and clinical studies employed a thick layer of lidocaine and prilocaine cream (1 to 2 g/10 cm 2 ). The duration of application prior to venipuncture was 1 hour. The duration of application prior to taking split thickness skin grafts was 2 hours. A thinner application has not been studied and may result in less complete analgesia or a shorter duration of adequate analgesia. The systemic absorption of lidocaine and prilocaine is a side effect of the desired local effect. The amount of drug absorbed depends on surface area and duration of application. The systemic blood levels depend on the amount absorbed and patient size (weight) and the rate of systemic drug elimination. Long duration of application, large treatment area, small patients, or impaired elimination may result in high blood levels. The systemic blood levels are typically a small fraction (1/20 to 1/36) of the blood levels that produce toxicity. Table 2 below gives maximum recommended doses, application areas and application times for infants and children. TABLE 2 LIDOCAINE AND PRILOCAINE CREAM MAXIMUM RECOMMENDED DOSE, APPLICATION AREA, AND APPLICATION TIME BY AGE AND WEIGHT* For Infants and Children Based on Application to Intact Skin Please note: If a patient greater than 3 months old does not meet the minimum weight requirement, the maximum total dose of lidocaine and prilocaine cream should be restricted to that which corresponds to the patient's weight. * These are broad guidelines for avoiding systemic toxicity in applying lidocaine and prilocaine cream to patients with normal intact skin and with normal renal and hepatic function. ** For more individualized calculation of how much lidocaine and prilocaine may be absorbed, physicians can use the following estimates of lidocaine and prilocaine absorption for children and adults: The estimated mean ( SD) absorption of lidocaine is 0.045 ( 0.016) mg/cm 2 /hr. The estimated mean ( SD) absorption of prilocaine is 0.077 ( 0.036) mg/cm 2 /hr. Age and Body Weight Requirements Maximum Total Dose of Lidocaine and Prilocaine cream Maximum Application Area** Maximum Application Time 0 up to 3 months or> <5 kg 1 g 10 cm 2 1 hour 3 up to 12 months and> 5 kg 2 g 20 cm 2 4 hours 1 to 6 years and > 10 kg 10 g 100 cm 2 4 hours 7 to 12 years and > 20 kg 20 g 200 cm 2 4 hours An I.V. antiarrhythmic dose of lidocaine is 1 mg/kg (70 mg/70 kg) and gives a blood level of about 1 μg/mL. Toxicity would be expected at blood levels above 5 μg/mL. Smaller areas of treatment are recommended in a debilitated patient, a small child or a patient with impaired elimination. Decreasing the duration of application is likely to decrease the analgesic effect. Indications and Usage for DermacinRx Prizopak Lidocaine and prilocaine cream (a eutectic mixture of lidocaine 2.5% and prilocaine 2.5%) is indicated as a topical anesthetic for use on: - normal intact skin for local analgesia. - genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anesthesia. Lidocaine and prilocaine cream is not recommended in any clinical situation when penetration or migration beyond the tympanic membrane into the middle ear is possible because of the ototoxic effects observed in animal studies (see WARNINGS ). CONTRAINDICATIONS Lidocaine and prilocaine cream (lidocaine 2.5% and prilocaine 2.5%) is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type or to any other component of the product. Warnings Application of lidocaine and prilocaine cream to larger areas or for longer times than those recommended could result in sufficient absorption of lidocaine and prilocaine resulting in serious adverse effects (see Individualization of Dose ). Patients treated with class III anti-arrhythmic drugs (e.g., amiodarone, bretylium, sotalol, dofetilide) should be under close surveillance and ECG monitoring considered, because cardiac effects may be additive. Studies in laboratory animals (guinea pigs) have shown that lidocaine and prilocaine cream has an ototoxic effect when instilled into the middle ear. In these same studies, animals exposed to lidocaine and prilocaine cream only in the external auditory canal, showed no abnormality. Lidocaine and prilocaine cream should not be used in any clinical situation when its penetration or migration beyond the tympanic membrane into the middle ear is possible. Methemoglobinemia: Lidocaine and prilocaine cream should not be used in those rare patients with congenital or idiopathic methemoglobinemia and in infants under the age of twelve months who are receiving treatment with methemoglobin-inducing agents. Very young patients or patients with glucose-6-phosphate dehydrogenase deficiencies are more susceptible to methemoglobinemia. Patients taking drugs associated with drug-induced methemoglobinemia such as sulfonamides, acetaminophen, acetanilid, aniline dyes, benzocaine, chloroquine, dapsone, naphthalene, nitrates and nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine, are also at greater risk for developing methemoglobinemia. There have been reports of significant methemoglobinemia (20 to 30%) in infants and children following excessive applications of lidocaine and prilocaine cream. These cases involved the use of large doses, larger than recommended areas of application, or infants under the age of 3 months who did not have fully mature enzyme systems. In addition, a few of these cases involved the concomitant administration of methemoglobin-inducing agents. Most patients recovered spontaneously after removal of the cream. Treatment with IV methylene blue may be effective if required. Physicians are cautioned to make sure that parents orother caregivers understand the need for careful application of lidocaine and prilocaine cream, to ensure that the doses and areas of application recommended in Table 2 are not exceeded (especially in children under the age of 3 months) and to limit the period of application to the minimum required to achieve the desired anesthesia. Neonates and infants up to 3 months of age should be monitored for Met-Hb levels before, during, and after the application of lidocaine and prilocaine cream, provided the test results can be obtained quickly. PRECAUTIONS General: Repeated doses of lidocaine and prilocaine cream may increase blood levels of lidocaine and prilocaine. Lidocaine and prilocaine cream should be used with caution in patients who may be more sensitive to the systemic effects of lidocaine and prilocaine including acutely ill, debilitated, or elderly patients. Lidocaine and prilocaine cream should not be applied to open wounds. Care should be taken not to allow lidocaine and prilocaine cream to come in contact with the eye because animal studies have demonstrated severe eye irritation. Also the loss of protective reflexes can permit corneal irritation and potential abrasion. Absorption of lidocaine and prilocaine cream in conjunctival tissues has not been determined. If eye contact occurs, immediately wash out the eye with water or saline and protect the eye until sensation returns. Patients allergic to paraaminobenzoic acid derivatives (procaine, tetracaine, benzocaine, etc.) have not shown cross sensitivity to lidocaine and/or prilocaine, however, lidocaine and prilocaine cream should be used with caution in patients with a history of drug sensitivities, especially if the etiologic agent is uncertain. Patients with severe hepatic disease, because of their inability to metabolize local anesthetics normally, are at greater risk of developing toxic plasma concentrations of lidocaine and prilocaine. Lidocaine and prilocaine have been shown to inhibit viral and bacterial growth. The effect of lidocaine and prilocaine cream on intradermal injections of live vaccines has not been determined. Information for Patients: When lidocaine and prilocaine cream is used, the patient should be aware that the production of dermal analgesia may be accompanied by the block of all sensations in the treated skin. For this reason, the patient should avoid inadvertent trauma to the treated area by scratching, rubbing, or exposure to extreme hot or cold temperatures until complete sensation has returned. Lidocaine and prilocaine cream should not be applied near the eyes or on open wounds. Drug Interactions: Lidocaine and prilocaine cream should be used with caution in patients receiving Class I antiarrhythmic drugs (such as tocainide and mexiletine) since the toxic effects are additive and potentially synergistic. Prilocaine may contribute to the formation of methemoglobin in patients treated with other drugs known to cause this condition (see Methemoglobinemia subsection of WARNINGS ). Specific interaction studies with lidocaine/prilocaine and class III anti-arrhythmic drugs (e.g., amiodarone, bretylium, sotalol, doetilide) have not been performed, but caution is advised (see WARNINGS ). Should lidocaine and prilocaine cream be used concomitantly with other products containing lidocaine and/or prilocaine, cumulative doses from all formulations must be considered. Carcinogenesis, Mutagenesis, Impairment of Fertility Carcinogenesis: Long-term studies in animals designed to evaluate the carcinogenic potential of lidocaine and prilocaine have not been conducted. Metabolites of prilocaine have been shown to be carcinogenic in laboratory animals. In the animal studies reported below, doses or blood levels are compared with the Single Dermal Administration (SDA) of 60 g of lidocaine and prilocaine cream to 400 cm 2 for 3 hours to a small person (50 kg). The typical application of lidocaine and prilocaine cream for one or two treatments for venipuncture sites (2.5 or 5 g) would be 1/24 or 1/12 of that dose in an adult or about the same mg/kg dose in an infant. Chronic oral toxicity studies of ortho -toluidine, a metabolite of prilocaine, in mice (450 to 7200 mg/m 2 ; 60 to 960 times SDA) and rats (900 to 4,800 mg/m 2 ; 60 to 320 times SDA) have shown that ortho -toluidine is a carcinogen in both species. The tumors included hepatocarcinomas/adenomas in female mice, multiple occurrences of hemangiosarcomas/hemangiomas in both sexes of mice, sarcomas of multiple organs, transitional-cell carcinomas/papillomas of urinary bladder in both sexes of rats, subcutaneous fibromas/fibrosarcomas and mesotheliomas in male rats, and mammary gland fibroadenomas/adenomas in female rats. The lowest dose tested (450 mg/m 2 in mice, 900 mg/m 2 in rats; 60 times SDA) was carcinogenic in both species. Thus the no-effect dose must be less than 60 times SDA. The animal studies were conducted at 150 to 2,400 mg/kg in mice and at 150 to 800 mg/kg in rats. The dosages have been converted to mg/m 2 for the SDA calculations above. Mutagenesis: The mutagenic potential of lidocaine HCl has been tested in a bacterial reverse (Ames) assay in Salmonella, an in vitro chromosomal aberration assay using human lymphocytes an in vivo micronucleus test in mice. There was no indication of mutagenicity or structural damage to chromosomes in these tests. Ortho -toluidine, a metabolite of prilocaine, at a concentration of 0.5 μg/mL, was genotoxic in Escherichia coli DNA repair and phage-induction assays. Urine concentrates from rats treated with ortho -toluidine (300 mg/kg orally; 300 times SDA) were mutagenic when examined in Salmonella typhimurium in the presence of metabolic activation. Several other tests on ortho -toluidine, including reverse mutations in five different Salmonella typhimurium strains in the presence or absence of metabolic activation and a study to detect single strand breaks in DNA of V79 Chinese hamster cells, were negative. Impairment of Fertility: See Use in Pregnancy . Use in Pregnancy: Teratogenic Effects: Pregnancy Category B. Reproduction studies with lidocaine have been performed in rats and have revealed no evidence of harm to the fetus (30 mg/kg subcutaneously; 22 times SDA). Reproduction studies with prilocaine have been performed in rats and have revealed no evidence of impaired fertility or harm to the fetus (300 mg/kg intramuscularly; 188 times SDA). There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, lidocaine and prilocaine cream should be used during pregnancy only if clearly needed. Reproduction studies have been performed in rats receiving subcutaneous administration of an aqueous mixture containing lidocaine HCl and prilocaine HCl at 1:1 (w/w). At 40 mg/kg each, a dose equivalent to 29 times SDA lidocaine and 25 times SDA prilocaine, no teratogenic, embryotoxic or fetotoxic effects were observed. Labor and Delivery : Neither lidocaine nor prilocaine are contraindicated in labor and delivery. Should lidocaine and prilocaine cream be used concomitantly with other products containing lidocaine and/or prilocaine, cumulative doses from all formulations must be considered. Nursing Mothers: Lidocaine, and probably prilocaine, are excreted in human milk. Therefore, caution should be exercised when lidocaine and prilocaine cream is administered to a nursing mother since the milk:plasma ratio of lidocaine is 0.4 and is not determined for prilocaine. Pediatric Use: Controlled studies of lidocaine and prilocaine cream in children under the age of seven years have shown less overall benefit than in older children or adults. These results illustrate the importance of emotional and psychological support of younger children undergoing medical or surgical procedures. Lidocaine and prilocaine cream should be used with care in patients with conditions or therapy associated with methemoglobinemia (see Methemoglobinemia subsection of WARNINGS ). When using lidocaine and prilocaine cream in young children, especially infants under the age of 3 months, care must be taken to insure that the caregiver understands the need to limit the dose and area of application, and to prevent accidental ingestion (see DOSAGE AND ADMINISTRATION and Methemoglobinemia ). In neonates (minimum gestation age: 37 weeks) and children weighing less than 20 kg, the area and duration of application should be limited (see TABLE 2 in Individualization of Dose ). Studies have not demonstrated the efficacy of lidocaine and prilocaine cream for heel lancing in neonates. Geriatric Use: Of the total number of patients in clinical studies of lidocaine and prilocaine cream, 180 were age 65 to 74 and 138 were 75 and over. No overall differences in safety or efficacy were observed between these patients and younger patients. Other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Plasma levels of lidocaine and prilocaine in geriatric and non-geriatric patients following application of a thick layer of lidocaine and prilocaine cream are very low and well below potentially toxic levels. However, there are no sufficient data to evaluate quantitative differences in systemic plasma levels of lidocaine and prilocaine between geriatric and non-geriatric patients following application of lidocaine and prilocaine cream. Consideration should be given for those elderly patients who have enhanced sensitivity to systemic absorption (see PRECAUTIONS ). After intravenous dosing, the elimination half-life of lidocaine is significantly longer in elderly patients (2.5 hours) than in younger patients (1.5 hours). (See CLINICAL PHARMACOLOGY ). Adverse Reactions Localized Reactions: During or immediately after treatment with lidocaine and prilocaine cream on intact skin, the skin at the site of treatment may develop erythema or edema or may be the locus of abnormal sensation. Rare cases of discrete purpuric or petechial reactions at the application site have been reported. Rare cases of hyperpigmentation following the use of lidocaine and prilocaine cream have been reported. The relationship to lidocaine and prilocaine cream or the underlying procedure has not been established. In clinical studies on intact skin involving over 1,300 lidocaine and prilocaine cream-treated subjects, one or more such local reactions were noted in 56% of patients, and were generally mild and transient, resolving spontaneously within 1 or 2 hours. There were no serious reactions that were ascribed to lidocaine and prilocaine cream. Two recent reports describe blistering on the foreskin in neonates about to undergo circumcision. Both neonates received 1.0 g of lidocaine and prilocaine cream. In patients treated with lidocaine and prilocaine cream on intact skin, local effects observed in the trials included: paleness (pallor or blanching) 37%, redness (erythema) 30%, alterations in temperature sensations 7%, edema 6%, itching 2% and rash, less than 1%. In clinical studies on genital mucous membranes involving 378 lidocaine and prilocaine cream-treated patients, one or more application site reactions, usually mild and transient, were noted in 41% of patients. The most common application site reactions were redness (21%), burning sensation (17%) and edema (10%). Allergic Reactions: Allergic and anaphylactoid reactions associated with lidocaine or prilocaine can occur. They are characterized by urticaria, angioedema, bronchospasm, and shock. If they occur they should be managed by conventional means. The detection of sensitivity by skin testing is of doubtful value. Systemic (Dose Related) Reactions: Systemic adverse reactions following appropriate use of lidocaine and prilocaine cream are unlikely due to the small dose absorbed (see Pharmacokinetics subsection of CLINICAL PHARMACOLOGY ). Systemic adverse effects of lidocaine and/or prilocaine are similar in nature to those observed with other amide local anesthetic agents including CNS excitation and/or depression (light-headedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest). Excitatory CNS reactions may be brief or not occur at all, in which case the first manifestation may be drowsiness merging into unconsciousness. Cardiovascular manifestations may include bradycardia, hypotension and cardiovascular collapse leading to arrest. OVERDOSAGE Peak blood levels following a 60 g application to 400 cm 2 of intact skin for 3 hours are 0.05 to 0.16 μg/mL for lidocaine and 0.02 to 0.10 μg/mL for prilocaine. Toxic levels of lidocaine (>5 μg/mL) and/or prilocaine (>6 μg/mL) cause decreases in cardiac output, total peripheral resistance and mean arterial pressure. These changes may be attributable to direct depressant effects of these local anesthetic agents on the cardiovascular system. In the absence of massive topical overdose or oral ingestion, evaluation should include evaluation of other etiologies for the clinical effects or overdosage from other sources of lidocaine, prilocaine or other local anesthetics. Consult the package inserts for parenteral Xylocaine (lidocaine HCl) or Citanest (prilocaine HCl) for further information for the management of overdose. DermacinRx Prizopak Dosage and Administration Adult Patients-Intact Skin A thick layer of lidocaine and prilocaine cream is applied to intact skin and covered with an occlusive dressing (see INSTRUCTIONS FOR APPLICATION ). Minor Dermal Procedures: For minor procedures such as intravenous cannulation and venipuncture, apply 2.5 grams of lidocaine and prilocaine cream (1/2 the 5 g tube) over 20 to 25 cm 2 of skin surface for at least 1 hour. In controlled clinical trials using lidocaine and prilocaine cream, two sites were usually prepared in case there was a technical problem with cannulation or venipuncture at the first site. Major Dermal Procedures: For more painful dermatological procedures involving a larger skin area such as split thickness skin graft harvesting, apply 2 grams of lidocaine and prilocaine cream per 10 cm 2 of skin and allow to remain in contact with the skin for at least 2 hours. Adult Male Genital Skin: As an adjunct prior to local anesthetic infiltration, apply a thick layer of lidocaine and prilocaine cream (1 g/10 cm 2 ) to the skin surface for 15 minutes. Local anesthetic infiltration should be performed immediately after removal of lidocaine and prilocaine cream. Dermal analgesia can be expected to increase for up to 3 hours under occlusive dressing and persist for 1 to 2 hours after removal of the cream. The amount of lidocaine and prilocaine absorbed during the period of application can be estimated from the information in Table 2, ** footnote, in Individualization of Dose . Adult Female Patients-Genital Mucous Membranes For minor procedures on the female external genitalia, such as removal of condylomata acuminata, as well as for use as pretreatment for anesthetic infiltration, apply a thick layer (5 to 10 grams) of lidocaine and prilocaine cream for 5 to 10 minutes. Occlusion is not necessary for absorption, but may be helpful to keep the cream in place. Patients should be lying down during the lidocaine and prilocaine cream application, especially if no occlusion is used. The procedure or the local anesthetic infiltration should be performed immediately after the removal of lidocaine and prilocaine cream. Pediatric Patients-Intact Skin The following are the maximum recommended doses, application areas and application times for lidocaine and prilocaine cream based on a child's age and weight: Age and Body Weight Requirements Maximum Total Dose of Lidocaine and Prilocaine Cream Maximum Application Area Maximum Application Time 0 up to 3 months or <5 kg 1 g 10 cm 2 1 hour 3 up to 12 months and> 5 kg 2 g 20 cm 2 4 hours 1 to 6 years and > 10 kg 10 g 100 cm 2 4 hours 7 to 12 years and > 20 kg 20 g 200 cm 2 4 hours Please note: If a patient greater than 3 months old does not meet the minimum weight requirement, the maximum total dose of lidocaine and prilocaine cream should be restricted to that which corresponds to the patient's weight (see INSTRUCTIONS FOR APPLICATION ). Practitioners should carefully instruct caregivers to avoid application of excessive amounts of lidocaine and prilocaine cream (see PRECAUTIONS ). When applying lidocaine and prilocaine cream to the skin of young children, care must be taken to maintain careful observation of the child to prevent accidental ingestion of lidocaine and prilocaine cream or the occlusive dressing. A secondary protective covering to prevent inadvertent disruption of the application site may be useful. Lidocaine and prilocaine cream should not be used in neonates with a gestational age less than 37 weeks nor in infants under the age of 12 months who are receiving treatment with methemoglobin-inducing agents (see Methemoglobinemia subsection of WARNINGS ). When lidocaine and prilocaine cream (lidocaine 2.5% and prilocaine 2.5%) is used concomitantly with other products containing local anesthetic agents, the amount absorbed from all formulations must be considered (see Individualization of Dose ). The amount absorbed in the case of lidocaine and prilocaine cream is determined by the area over which it is applied and the duration of application under occlusion (see Table 2, ** footnote, in Individualization of Dose ). Although the incidence of systemic adverse reactions with lidocaine and prilocaine cream is very low, caution should be exercised, particularly when applying it over large areas and leaving it on for longer than 2 hours. The incidence of systemic adverse reactions can be expected to be directly proportional to the area and time of exposure (see Individualization of Dose ). INSTRUCTIONS FOR APPLICATION: To measure 1 gram of lidocaine and prilocaine cream, the Cream should be gently squeezed out of the tube as a narrow strip that is 1.5 inches (3.8 cm) long and 0.2 inches (5 mm) wide. The strip of lidocaine and prilocaine cream should be contained within the lines of the diagram shown below. Use the number of strips that equals your dose, like the examples in the table below. Dosing Information 1 gram = 1 strip 2 grams = 2 strips 2.5 grams = 2.5 strips For adult and pediatric patients, apply ONLY as prescribed by your physician. If your child is below the age of 3 months or small for their age, please inform your doctor before applying lidocaine and prilocaine cream, which can be harmful, if applied over too much skin at one time in young children. When applying lidocaine and prilocaine cream to the intact skin of young children, it is important that they be carefully observed by an adult in order to prevent the accidental ingestion of or eye contact with lidocaine and prilocaine cream. Lidocaine and prilocaine cream must be applied to intact skin at least 1 hour before the start of a routine procedure and for 2 hours before the start of a painful procedure. A protective covering of the cream is not necessary for absorption but may be helpful to keep the cream in place. If using a protective covering, your doctor will remove it, wipe off the lidocaine and prilocaine cream, and clean the entire area with an antiseptic solution before the procedure. The duration of effective skin anesthesia will be at least 1 hour after removal of the protective covering. Precautions Do not apply near eyes or open wounds. Keep out of the reach of children. If your child becomes very dizzy, excessively sleepy, or develops duskiness of the face or lips after applying lidocaine and prilocaine cream, remove the cream and contact the child's physician at once. How is DermacinRx Prizopak Supplied Lidocaine 2.5% and Prilocaine 2.5% Cream, USP is available as the following: NDC 0591-2070-30 30 gram/tube packed individually, in a child-resistant tube. KEEP CONTAINER TIGHTLY CLOSED AT ALL TIMES WHEN NOT IN USE. NOT FOR OPHTHALMIC USE. Storage: Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature]. Rx only Keep out of the reach of children. For all medical inquiries contact: ACTAVIS Medical Communications Parsippany, NJ 07054 1-800-272-5525 Manufactured By: IGI Laboratories Inc. Buena, NJ 08310 USA DermacinRx Prizopak (Lidocaine 2.5% and Prilocaine 2.5% Cream, USP and Frame Style Transparent Dressing) Packaged in the USA by: PureTek Corporation San Fernando, CA 91340 For questions or information call toll-free: 877-921-7873 visit: dermacinrx.com Rev. 36742 DermacinRx Prizopak lidocaine and prilocaine kit Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:59088-873 Packaging # Item Code Package Description 1 NDC:59088-873-00 1 KIT in 1 PACKAGE Quantity of Parts Part # Package Quantity Total Product Quantity Part 1 3 TUBE 90 g Part 1 of 1 LIDOCAINE AND PRILOCAINE lidocaine and prilocaine cream Product Information Item Code (Source) NDC:0591-2070 Route of Administration TOPICAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength LIDOCAINE (LIDOCAINE) LIDOCAINE 25 mg in 1 g PRILOCAINE (PRILOCAINE) PRILOCAINE 25 mg in 1 g Inactive Ingredients Ingredient Name Strength PEG-55 HYDROGENATED CASTOR OIL CARBOMER HOMOPOLYMER TYPE B (ALLYL SUCROSE CROSSLINKED) WATER SODIUM HYDROXIDE Packaging # Item Code Package Description 1 NDC:0591-2070-30 1 TUBE in 1 CARTON 1 30 surgical procedure


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expect Dermtex HC Generic Name: hydrocortisone topical (hye droe KOR ti sone) Brand Name: Ala-Cort, Aquanil HC, Beta HC, Caldecort, Cortaid, Dermarest Plus Anti-Itch, Dermasorb HC, Dermtex HC, Gynecort Maximum Strength, Instacort, Itch-X Lotion, Locoid, Pandel, Pediaderm HC, Sarnol-HC, Scalacort, Texacort, U-Cort, Westcort Overview Side Effects Dosage Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A What is Dermtex HC (hydrocortisone topical)? Hydrocortisone is a topical steroid that reduces the actions of chemicals in the body that cause inflammation. Hydrocortisone topical is used to treat inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, or psoriasis. There are many brands and forms of hydrocortisone topical available and not all brands are listed on this leaflet. Hydrocortisone topical may also be used for purposes not listed in this medication guide. Slideshow Prednisone: 12 Things You Should Know What is the most important information I should know about Dermtex HC (hydrocortisone topical)? Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. What should I discuss with my healthcare provider before using Dermtex HC (hydrocortisone topical)? You should not use this medicine if you are allergic to hydrocortisone. Hydrocortisone topical will not treat a bacterial, fungal, or viral skin infection. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially: diabetes; liver disease; or problems with your adrenal gland. It is not known whether hydrocortisone topical will harm an unborn baby. Ask a doctor before using this medicine if you are pregnant. It is not known whether hydrocortisone topical passes into breast milk or if it could affect a nursing baby. Ask a doctor before using this medicine if you are breast-feeding. Do not use this medicine on a child without medical advice. How should I use Dermtex HC (hydrocortisone topical)? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Hydrocortisone topical will not treat a bacterial, fungal, or viral skin infection. Wash your hands before and after each application, unless you are using hydrocortisone topical to treat a hand condition. Apply a small amount to the affected area and rub it gently into the skin. Avoid using this medicine on your face, near your eyes or mouth, or on body areas where you have skin folds or thin skin. Do not cover the treated skin area unless your doctor tells you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Call your doctor if your symptoms do not improve, or if they get worse while using hydrocortisone topical. Store at room temperature away from moisture and heat. What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. An overdose of hydrocortisone topical is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using Dermtex HC (hydrocortisone topical)? Do not take by mouth. Hydrocortisone topical is for use only on the skin. Do not use this medicine on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. If this medication gets in your eyes, nose, mouth, rectum, or vagina, rinse with water. Rinse with water if this medication gets in your eyes. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Dermtex HC (hydrocortisone topical) side effects Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body. Stop using hydrocortisone topical and call your doctor if you have: weight gain (especially in your face or your upper back and torso); slow wound healing, thinning skin, increased body hair; irregular menstrual periods, changes in sexual function; or muscle weakness, tired feeling, depression, anxiety, feeling irritable. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. Common side effects may include: acne, skin redness; mild burning, tingling or prickly feeling; changes in skin color; or dryness or cracking of treated skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect Dermtex HC (hydrocortisone topical)? It is not likely that other drugs you take orally or inject will have an effect on topically applied hydrocortisone. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Next Side Effects Print this page Add to My Med List More about Dermtex HC (hydrocortisone topical) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: topical steroids Consumer resources Dermtex-HC (Advanced Reading) Other brands: Anusol-HC , Proctosol-HC , Proctozone HC , Westcort , ... +49 more Professional resources Hydrocortisone topical (AHFS Monograph) Hydrocortisone in Absorbase (FDA) Related treatment guides Atopic Dermatitis Dermatitis Eczema Intertrigo ... +4 more Where can I get more information? Your pharmacist can provide more information about hydrocortisone topical. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 10.01. Date modified: December 03, 2017 Last reviewed: August 22, 2017} Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Topical steroids Related Drugs Eczema prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , clobetasol topical , More... Atopic Dermatitis prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , methylprednisolone , More... Pruritus hydroxyzine , lidocaine topical , hydrocortisone topical , diphenhydramine , Benadryl , More... Skin Rash prednisone , hydrocortisone topical , Deltasone , Westcort , More... 4 more conditions... Dermtex HC Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the Dermtex HC support group to connect with others who have similar interests.} } continual


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everything Sex Addiction, Porn, and Problematic Sexual Behavior various
 
Photo :Sex Addiction, Porn, and Problematic Sexual Behavior
all of sudden May 31, 2017 By Leah Briick, Executive Director and David Lewis, Board Member, Society for the Advancement of Sexual Health (SASH) In today s world, sex addiction has become a term that is often seen in the media or discussed in the news. Celebrities, athletes, and reality show stars identify themselves as sex addicts and the media perpetuate the term by giving these stories more than their fair share of coverage after all, juicy stories make for good ratings. But the term sex addiction is tricky. First, the term addiction itself is being increasingly applied to many disorders; perhaps too many. Additionally, pairing the terms sex and addiction in a two-word phrase stirs up an almost unavoidable set of emotionally-charged conclusions. For these reasons, at The Society for the Advancement of Sexual Health (SASH) we prefer to use the term Problematic Sexual Behavior to help more closely identify and diagnose sexual health issues. Problematic Sexual Behavior can be defined as any repetitive sexual behavior that exceeds a person's relationship commitments, personal values or self-control. One of the most common forms of problematic sexual behavior is the use of pornography. For the purposes of this blog, we re not talking about pornography that involves people who are underage or acts of sexual violence. In 2016 alone, nearly 4.6 billion hours of pornography was watched on the world s largest porn site. That amount of time is the equivalent of 524,641 years! While use of pornography itself is not necessarily a problematic sexual behavior, it can become one when it causes stressors to appear in a person s life. Environmental stressors might include arguments and complaints about the use of pornography from significant others, or disruption in work or school performance. Internalized stressors include self-loathing, self-doubt and shame associated with one's use of pornography. A common response to either environmental or internal stressors is continued use of pornography despite the desire to stop or ongoing relationship issues. Ongoing behavior despite consequences also helps to determine whether symptoms of problematic sexual behavior exist. The sexual health field is emerging and changing. New research is being published daily and changes to treatment practices are adapted based on new findings. Individuals that need care should seek out professionals that have sufficient training to ensure needs are met. One way to find treatment providers with training in sexual health issues is to search The Society for the Advancement of Sexual Health s member directory . Click here to access the directory. With new research, treatments, and awareness, comes hope for recovery and a life with meaningful sexual health. Recovery does happen. The Society for the Advancement of Sexual Health (SASH) is a nonprofit organization dedicated to promoting sexual health and addressing the escalating consequences of problematic sexual behaviors affecting individuals, families and communities. Seeking collaboration among clinical, educational, legal, policy, and research professionals, SASH advocates a multifactorial approach to address problematic sexual behaviors, further research and to promote sexual health in general. Follow SASH on Facebook and Twitter to learn more. Tags: MHM2017 may is mental health month Mental Health Month sex sex addiction problematic sexual behavior sexual health Mental Health America Blog cures


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offices Eth-Oxydose (Oral) travelers
 
Photo :Eth-Oxydose (Oral)
organization Eth-Oxydose (Oral) Generic Name: oxycodone (Oral route) ox-i-KOE-done Overview Side Effects Dosage Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Oral route(Capsule, Extended Release) Misuse and abuse may lead to overdose and death. Assess risk before subscribing and regularly monitor for signs of these behaviors and conditions. Serious and potentially fatal respiratory depression may occur. Monitor for respiratory depression, particularly when initiating or increasing dosage. Accidental ingestion of one dose or more can lead to fatal overdose, especially in children. Prolonged use during pregnancy can lead to potentially life-threatening neonatal opioid withdrawal syndrome. Initiation of CYP3A4 inhibitors or discontinuation of CYP3A4 inducers may result in an increase in oxycodone plasma concentrations, which could increase or prolong adverse drug effects and may cause potentially fatal respiratory depression. Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation . Oral route(Tablet;Tablet, Extended Release) Addiction, abuse, and misuse, leading to overdose and death has been reported. Before prescribing, assess the patient's risk and watch for signs of the development of these behaviors. Serious and fatal respiratory depression may occur. Monitor for respiratory depression, especially when beginning treatment or increasing dose. Advise patients to swallow tablets whole to avoid overdose. Accidental ingestion can result in a fatal overdose, especially in children. Prolonged use in pregnancy may lead to life-threatening neonatal withdrawal syndrome. If oxycodone hydrochloride must be used during pregnancy, advise the patient of the risk and ensure that treatment will be available to the infant. Initiation of CYP3A4 inhibitors or discontinuation of CYP3A4 inducers can cause a fatal oxycodone hydrochloride overdose. Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation . Oral route(Solution) Use caution when prescribing and administering oxycodone oral solution as dosing errors due to mg and mL could result in accidental overdose and death. Ensure the proper dose is indicated and dispensed. Oxycodone oral solution should be kept out of the reach of children. Seek emergency help immediately if accidental ingestion occurs . Commonly used brand name(s) In the U.S. Dazidox Eth-Oxydose Oxaydo OxyCONTIN OxyCONTIN CR Oxydose Oxyfast Oxy IR Roxicodone Roxicodone Intensol Roxybond Xtampza ER Available Dosage Forms: Capsule, Extended Release Tablet, Extended Release Tablet Capsule Solution Therapeutic Class: Analgesic Chemical Class: Opioid Slideshow Tramadol: 9 Things You Should Know Uses For Eth-Oxydose Oxycodone is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Oxycodone acts on the central nervous system (CNS) to relieve pain. Oxycodone extended-release capsules or tablets should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations when non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or "as needed". When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. This medicine is available only with your doctor's prescription. Before Using Eth-Oxydose In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of Oxaydo , Roxicodone , and Xtampza ER in the pediatric population. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Oxycontin in children. However, safety and efficacy have not been established in children younger than 11 years of age. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxycodone in the elderly. However, elderly patients are more likely to have age-related lung, liver, or kidney problems, which may require caution and an adjustment in the dose for patients receiving oxycodone in order to avoid potentially serious side effects. Breast Feeding Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Nalmefene Naltrexone Safinamide Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abiraterone Acepromazine Alfentanil Almotriptan Alprazolam Alvimopan Amineptine Amiodarone Amisulpride Amitriptyline Amitriptylinoxide Amobarbital Amoxapine Amphetamine Amprenavir Anileridine Aprepitant Aripiprazole Asenapine Atazanavir Baclofen Benperidol Benzphetamine Boceprevir Bromazepam Bromopride Brompheniramine Buprenorphine Buspirone Butabarbital Butorphanol Carbamazepine Carbinoxamine Carisoprodol Carphenazine Ceritinib Chloral Hydrate Chlordiazepoxide Chlorpheniramine Chlorpromazine Chlorzoxazone Citalopram Clarithromycin Clobazam Clomipramine Clonazepam Clorazepate Clozapine Cobicistat Cocaine Codeine Conivaptan Cyclobenzaprine Darunavir Desipramine Desmopressin Desvenlafaxine Dexmedetomidine Dextroamphetamine Dextromethorphan Dezocine Diazepam Dibenzepin Dichloralphenazone Difenoxin Dihydrocodeine Diphenhydramine Diphenoxylate Dolasetron Donepezil Doxepin Doxylamine Droperidol Duloxetine Eletriptan Enflurane Enzalutamide Erythromycin Escitalopram Estazolam Eszopiclone Ethchlorvynol Ethopropazine Ethylmorphine Fentanyl Flibanserin Fluoxetine Fluphenazine Flurazepam Fluspirilene Fluvoxamine Fosaprepitant Fosphenytoin Fospropofol Frovatriptan Furazolidone Granisetron Halazepam Haloperidol Halothane Hexobarbital Hydrocodone Hydromorphone Hydroxytryptophan Hydroxyzine Idelalisib Imipramine Indinavir Iproniazid Isocarboxazid Isoflurane Itraconazole Ketamine Ketazolam Ketobemidone Ketoconazole Levomilnacipran Levorphanol Linezolid Lisdexamfetamine Lithium Lofepramine Lopinavir Lorazepam Lorcaserin Loxapine Lumacaftor Meclizine Melitracen Melperone Meperidine Mephobarbital Meprobamate Meptazinol Mesoridazine Metaxalone Methadone Methamphetamine Methdilazine Methocarbamol Methohexital Methotrimeprazine Methylene Blue Methylnaltrexone Midazolam Milnacipran Mirtazapine Mitotane Moclobemide Molindone Moricizine Morphine Morphine Sulfate Liposome Nalbuphine Nalorphine Naloxone Naratriptan Nefazodone Nelfinavir Nialamide Nicomorphine Nitrazepam Nitrous Oxide Nortriptyline Olanzapine Ondansetron Opipramol Opium Opium Alkaloids Orphenadrine Oxazepam Oxymorphone Palonosetron Papaveretum Paregoric Paroxetine Pentazocine Pentobarbital Perampanel Perazine Periciazine Perphenazine Phenelzine Phenobarbital Phenytoin Pimozide Piperacetazine Pipotiazine Piritramide Posaconazole Prazepam Primidone Procarbazine Prochlorperazine Promazine Promethazine Propofol Protriptyline Quazepam Quetiapine Ramelteon Rasagiline Remifentanil Remoxipride Ribociclib Ritonavir Rizatriptan Samidorphan Saquinavir Secobarbital Selegiline Sertindole Sertraline Sibutramine Sodium Oxybate Sufentanil Sulpiride Sumatriptan Suvorexant Tapentadol Telaprevir Telithromycin Temazepam Thiethylperazine Thiopental Thiopropazate Thioridazine Tianeptine Tilidine Tizanidine Tolonium Chloride Topiramate Tramadol Tranylcypromine Trazodone Triazolam Trifluoperazine Trifluperidol Triflupromazine Trimeprazine Trimipramine Tryptophan Venlafaxine Vilazodone Vortioxetine Zaleplon Ziprasidone Zolmitriptan Zolpidem Zopiclone Zotepine Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Miconazole Rifampin St John's Wort Voriconazole Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Addison disease (adrenal gland problem) or Alcohol abuse, or history of or Brain tumor, history of or Breathing or lung problems (eg, hypoxia) or Cancer of the esophagus or colon or Central nervous system (CNS) depression or Chronic obstructive pulmonary disease (COPD) or Cor pulmonale (serious heart condition) or Drug dependence, especially with narcotics, or history of or Enlarged prostate (BPH, prostatic hypertrophy) or Gallbladder disease or gallstones or Head injuries, history of or Hypothyroidism (an underactive thyroid) or Hypovolemia (low blood volume) or Kyphoscoliosis (curvature of the spine with breathing problems) or Problems with passing urine or Psychosis (a mental disease) or Trouble swallowing or Weakened physical condition Use with caution. May increase risk for more serious side effects. Hypotension (low blood pressure) or Pancreatitis (inflammation or swelling of the pancreas) or Seizures, history of Use with caution. May make these conditions worse. Kidney disease, severe or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of oxycodone This section provides information on the proper use of a number of products that contain oxycodone. It may not be specific to Eth-Oxydose. Please read with care. Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence). This medicine comes with a Medication Guide and a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions. Oxycodone extended-release capsules or tablets should only be used by patients who have already been taking narcotic pain medicines, also called opioids. These patients are called opioid-tolerant . If you are uncertain whether or not you are opioid-tolerant, check with your doctor before using this medicine. Measure the oral liquid concentrate with the calibrated dropper that comes with the package. Your doctor may have you mix the concentrate with a small amount of liquid or food. Carefully follow the instructions and take the medicine mixture right away. Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Swallow the Oxaydo or OxyContin tablet whole with water. Do not break, crush, cut, chew, or dissolve it. Do not pre-soak, lick, or wet the tablet before placing it in the mouth. Take one tablet at a time. Also, do not give this medicine through nasogastric or feeding tubes. If you are using the extended release capsules: Take this medicine with food and with approximately the same amount of food each time. If you have trouble swallowing, you may open the capsule and sprinkle the contents on soft foods (eg, applesauce, pudding, ice cream, or jam) or into a cup and then give it directly into the mouth and swallow immediately. Drink a glass of water to make sure all medicine has been taken. This medicine may also be given through a feeding tube. Oxycodone extended-release capsules or tablets work differently from the regular oxycodone oral solution or tablets, even at the same dose. Do not switch from one brand or form to the other unless your doctor tells you to. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (extended-release capsules): For severe pain: Patients who are not taking narcotic medicines or are not opioid tolerant: Adults At first, 9 milligrams (mg) every 12 hours with food. Your doctor may adjust your dose if needed. However, the dose is usually not more than 288 mg per day. Children Use and dose must be determined by your doctor. Patients switching from other narcotic medicines: Adults The total amount of milligrams (mg) per day will be determined by your doctor and depends on which narcotic you were using. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For moderate to severe pain: Patients switching from regular oxycodone forms: Adults The tablet is given every 12 hours. The total amount of milligrams (mg) per day is the same as the total amount of regular oxycodone that is taken per day. The total amount per day will be divided and given as 2 doses during the day. Your doctor may adjust your dose if needed. Children 11 years of age and older Dose must be determined by your doctor. The patient must already be receiving and tolerating opioids for at least 5 consecutive days with a minimum of 20 mg per day of oxycodone or its equivalent for at least 2 days before taking OxyContin . Children younger than 11 years of age Use and dose must be determined by your doctor. Patients switching from other narcotic medicines: Adults The tablet is given every 12 hours. The total amount of milligrams (mg) per day will be determined by your doctor and depends on which narcotic you were using. The total amount per day will be divided and given as 2 doses during the day. Your doctor may adjust your dose if needed. Children 11 years of age and older Dose must be determined by your doctor. The patient must already be receiving and tolerating opioids for at least 5 consecutive days with a minimum of 20 mg per day of oxycodone or its equivalent for at least 2 days before taking OxyContin . Children younger than 11 years of age Use and dose must be determined by your doctor. Patients who are not taking narcotic medicines: Adults At first, 10 milligrams (mg) every 12 hours. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor. For oral dosage form (immediate-release tablets): For moderate to severe pain: Patients who are not taking narcotic medicines: Adults At first, 5 to 15 milligrams (mg) every 4 to 6 hours as needed. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor. Patients switching from other narcotic medicines: Adults The total amount of milligrams (mg) per day will be determined by your doctor and depends on which narcotic you were using. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor. For oral dosage forms (liquid concentrate, solution, or tablets): For moderate to severe pain: Adults 10 to 30 milligrams (mg) every 4 hours as needed. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Oxycodone can cause serious unwanted effects if taken by adults who are not used to strong narcotic pain medicines, children, or pets. Make sure you store the medicine in a safe and secure place to prevent others from getting it. Precautions While Using Eth-Oxydose It is very important that your doctor check your progress while you are taking this medicine . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Do not use this medicine if you are using or have used an MAO inhibitor within the past 14 days. This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Do not use more of this medicine or take it more often than your doctor tells you to. This can be life-threatening. Symptoms of an overdose include extreme dizziness or weakness, slow heartbeat or breathing, seizures, trouble breathing, and cold, clammy skin. Call your doctor right away if you notice these symptoms . This medicine will add to the effects of alcohol and other CNS depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics (numbing medicines), including some dental anesthetics. This effect may last for a few days after you stop using this medicine. Check with your doctor before taking any of these medicines while you are using this medicine . This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. If you have been using this medicine regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor . Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping. Using this medicine while you are pregnant may cause serious unwanted effects in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine. Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Eth-Oxydose Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Chills cold sweats confusion difficult or labored breathing dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fever tightness in the chest twitching Rare Abdominal or stomach pain bloating or swelling of the face, arms, hands, lower legs, or feet blood in the urine burning while urinating burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings chest pain convulsions cough decrease in the frequency of urination decrease in urine volume decreased urine output difficult or painful urination difficulty in passing urine (dribbling) difficulty with swallowing dizziness dry mouth fainting fast, irregular, pounding, or racing heartbeat or pulse feeling of warmth or heat flushing or redness of the skin, especially on the face and neck frequent urination headache hives, itching, or skin rash increase in heart rate increased thirst increased volume of pale, dilute urine lightheadedness muscle pain or cramps nausea or vomiting puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue rapid breathing rapid weight gain severe constipation severe vomiting shakiness in the legs, arms, hands, or feet sunken eyes sweating swelling or puffiness of the face swollen, painful, or tender lymph glands in the neck, armpit, or groin thirst tingling of the hands or feet trembling or shaking of the hands or feet unusual tiredness or weakness unusual weight gain or loss wrinkled skin Incidence not known Blurred vision choking clay-colored stools cold, clammy skin dark urine diarrhea fast, weak pulse gagging irregular, fast, slow, or shallow breathing loss of appetite pale or blue lips, fingernails, or skin unconsciousness unpleasant breath odor very slow heartbeat yellow eyes or skin Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Change in consciousness chest pain or discomfort constricted, pinpoint, or small pupils (black part of the eye) decreased awareness or responsiveness extreme drowsiness loss of consciousness no muscle tone or movement severe sleepiness slow or irregular heartbeat Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Difficulty having a bowel movement (stool) drowsiness lack or loss of strength relaxed and calm feeling sleepiness or unusual drowsiness Less common Abnormal dreams acid or sour stomach anxiety belching burning feeling in the chest or stomach false or unusual sense of well-being heartburn hiccups indigestion stomach discomfort, upset, or pain tenderness in the stomach area trouble sleeping weight loss Rare Absent, missed, or irregular menstrual periods bad, unusual or unpleasant (after) taste bloated or full feeling body aches or pain change in taste change in walking and balance changes in vision clumsiness or unsteadiness congestion continuous ringing or buzzing or other unexplained noise in the ears crying decreased interest in sexual intercourse dental caries or tooth decay depersonalization depression difficulty with speaking dry skin dryness or soreness of the throat excess air or gas in the stomach or intestines excessive muscle tone feeling of constant movement of self or surroundings feeling of unreality general feeling of discomfort or illness headache, severe and throbbing hearing loss hoarseness hyperventilation inability to have or keep an erection increase in body movements increased appetite increased cough irritability loss in sexual ability, desire, drive, or performance loss of heat from the body loss of memory loss of strength or energy muscle pain or weakness muscle stiffness muscle tension or tightness neck pain paranoia passing of gas problems with memory quick to react or overreact emotionally rapidly changing moods red, swollen skin restlessness runny nose scaly skin sensation of spinning sense of detachment from self or body severe sleepiness stomach pain, fullness, or discomfort swelling or inflammation of the mouth tender, swollen glands in the neck unusual weak feeling voice changes Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about ETH-Oxydose (oxycodone) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: narcotic analgesics Consumer resources Other brands: OxyContin , Roxicodone , Xtampza ER , OxyIR , ... +7 more Professional resources Oxycodone Hydrochloride (AHFS Monograph) Oxycodone Tablets (FDA) Related treatment guides Chronic Pain Pain} Drug Status Rx Availability Prescription only N Pregnancy Category Not classified 2 CSA Schedule High potential for abuse WADA Class Anti-Doping Classification Drug Class Narcotic analgesics Related Drugs Chronic Pain tramadol , oxycodone , Cymbalta , duloxetine , Percocet , morphine , fentanyl , Ultram , methadone , acetaminophen / oxycodone , OxyContin , More... Pain tramadol , acetaminophen , Tylenol , naproxen , oxycodone , aspirin , ibuprofen , amitriptyline , hydrocodone , clonidine , Norco , More... ETH-Oxydose Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the ETH-Oxydose support group to connect with others who have similar interests.} } contemplating


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selections Small Changes Could Keep Seniors Driving Longer to intensify

gifting away Small Changes Could Keep Seniors Driving Longer flattening
 
Photo :Small Changes Could Keep Seniors Driving Longer
further (*this news item will not be available after 02/27/2018) By Robert Preidt Wednesday, November 29, 2017 WEDNESDAY, Nov. 29, 2017 (HealthDay News) -- Older drivers can easily make their cars safer -- but few do, a new study finds. Pedal extensions, for example, help create a safe distance from the steering wheel/airbag and maximize visibility, safety experts say. Seat cushions improve sight line and may reduce back and hip pain, while steering wheel covers improve grip. But a survey of nearly 3,000 U.S. drivers aged 65 and older found fewer than 10 percent made use of these or other simple safety adaptations, according to the AAA Foundation for Traffic Safety. "While many seniors are considered to be safe drivers, they are also the most vulnerable," said David Yang, the foundation's executive director. Drivers 65 and older are more than twice as likely as younger drivers to be killed when involved in a crash, he pointed out in a foundation news release. "Our research suggests that most senior drivers are not taking advantage of simple and inexpensive features like steering wheel covers that can greatly improve their safety and the safety of others on the road," Yang said. And even among the senior drivers who had such devices, nearly 90 percent did not follow recommended advice and work with a trained professional to install them, the survey found. More than seven in 10 of the drivers in the study had health conditions that affect muscles and bones, including arthritis, hip/knee replacement and joint pains. Elin Schold-Davis is project coordinator of the American Occupational Therapy Association's older driver initiative. She said, "When an ache or pain begins hindering driving ability, many older drivers are able to continue driving safely after making a few adjustments." Occupational therapists can help recommend the right changes, Schold-Davis said. They're "especially valuable in connecting the dots between medical challenges that can affect driving and the appropriate equipment and adaptations needed to remain safely independent in the vehicle," she added. Other car adjustments that can help seniors stay on the road longer include convex or multifaceted mirrors that boost visibility and minimize blind spots. Also, hand controls can enable people to drive without using their feet, the AAA foundation said. SOURCE: AAA Foundation for Traffic Safety, news release, Nov. 29, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Motor Vehicle Safety Seniors' Health Recent Health News requisite


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for this reason camphor, lidocaine, and methyl salicylate (topical) influenced

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Photo :camphor, lidocaine, and methyl salicylate (topical)
superb camphor, lidocaine, and methyl salicylate (topical) Generic Name: camphor, lidocaine, and methyl salicylate (topical) (KAM for, LYE doe kane, METH il sa LIS i late TOP ik al) Brand Name: Viva Overview Side Effects Interactions Reviews Q & A More What is camphor, lidocaine, and methyl salicylate? Camphor is a mild pain reliever. Lidocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body. Methyl salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medicine works by reducing substances in the body that cause pain and inflammation. Camphor, lidocaine, and methyl salicylate topical (for the skin) is a combination medicine used to provide temporary relief of mild to moderate aches and pains of the muscles and joints. This medicine may be used for pain caused by muscle stiffness or bruising, arthritis, sprains or strains, backaches, and sore or bruised muscles. Camphor, lidocaine, and methyl salicylate may also be used for purposes not listed in this medication guide. Slideshow 7 First Aid Kit Must Haves For Your Medicine Cabinet What is the most important information I should know about camphor, lidocaine, and methyl salicylate? Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. What should I discuss with my healthcare provider before using camphor, lidocaine, and methyl salicylate? This medicine contains methyl salicylate, which is an NSAID. An NSAID can increase your risk of fatal heart attack or stroke, especially if you use it long term, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while using an NSAID. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). An NSAID may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using and NSAID, especially in older adults. You should not use this medicine if you are allergic to camphor, lidocaine, or methyl salicylate. To make sure camphor, lidocaine, and methyl salicylate is safe for you, tell your doctor if: you have high blood pressure or heart disease; you have ever had a stomach ulcer or bleeding problems; you drink 3 or more alcoholic drinks per day; you have kidney disease; you are allergic to any skin products; or you are allergic to any NSAID (aspirin, ibuprofen, celecoxib, diclofenac, indomethacin, meloxicam, naproxen, Advil, Motrin, Aleve, and others). Do not use this medicine without a doctor's advice if you are pregnant. Using methyl salicylate during the last 3 months of pregnancy may harm the unborn baby, or cause bleeding in the mother or the baby during delivery. It is not known whether camphor, lidocaine, or methyl salicylate could pass into breast milk or harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby. This medicine is not approved for use by anyone younger than 12 years old. How should I use camphor, lidocaine, and methyl salicylate? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine comes in a patch that you apply to your skin. Keep the patch away from your mouth, nose, and eyes. Wash your hands before applying a skin patch, and after removing it. Open the foil pouch and remove one skin patch. Reseal the pouch to protect the remaining patches. Remove the protective film from the sticky side of the patch. Apply the patch to clean and dry skin. Do not apply the patch over open wounds or sunburned, windburned, damaged, or irritated skin. Do not apply the skin patch to your face or your genitals. Do not wear more than one skin patch at a time. Using extra skin patches will not make the medicine more effective, and could increase your risk of heart attack or stroke. It may take up to several hours before you notice pain relief while wearing the skin patch. Remove the skin patch after 8 to 12 hours and replace it with a new one if needed. Do not use more than 2 skin patches in a 24-hour period. Call your doctor if your symptoms do not improve, or if they get worse while using this medicine. After removing a skin patch: fold it in half firmly with the sticky side in, and throw it away in a place where children and pets cannot get to it. Store unused skin patches at room temperature away from moisture, heat, and sunlight. Keep each patch in the foil pouch until ready to use. After opening a pouch, you must use the skin patches within 7 days. What happens if I miss a dose? Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if a child has placed a skin patch into his or her mouth. What should I avoid while using camphor, lidocaine, and methyl salicylate? Do not expose treated skin to heat from a hot tub, heating pad, or sauna. Heat can increase the amount of drug absorbed through your skin and may cause harmful effects. Rinse with water if the medicine gets in your eyes. Camphor, lidocaine, and methyl salicylate side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Remove the skin patch and get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Although the risk of serious side effects is low when medicine is applied to your skin, side effects can occur if the medicine is absorbed into your bloodstream. Stop using this medicine and call your doctor at once if you have: worsening of your muscle pain; skin rash, itching, or irritation; a light-headed feeling, like you might pass out; new or worsening stomach pain; or signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect camphor, lidocaine, and methyl salicylate? Tell your doctor about all your current medicines and any you start or stop using, especially: a diuretic or "water pill"; a blood thinner--warfarin, Coumadin, Jantoven; or an NSAID--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may interact with camphor, lidocaine, and methyl salicylate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Next Side Effects Print this page Add to My Med List More about camphor/lidocaine/methyl salicylate topical Side Effects Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: topical anesthetics Consumer resources Other brands: Viva Related treatment guides Muscle Pain Where can I get more information? Your pharmacist can provide more information about camphor, lidocaine, and methyl salicylate. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01. Date modified: December 03, 2017 Last reviewed: August 31, 2016} Drug Status OTC Availability Over the counter N/A CSA Schedule Not a controlled drug Drug Class Topical anesthetics Related Drugs Muscle Pain acetaminophen , Tylenol , naproxen , ibuprofen , diclofenac , Voltaren , Aleve , Advil , Naprosyn , Motrin , Paracetamol , Anaprox , Mapap , Cataflam , Tylenol Arthritis Pain , Zipsor , Motrin IB , Naprelan , Proprinal , More... Camphor / lidocaine / methyl salicylate topical Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the camphor / lidocaine / methyl salicylate support group to connect with others who have similar interests.} } take the plunge


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health practitioner Camphor/Pramoxine/Zinc once in a while

struggling with Camphor/Pramoxine/Zinc stressful
 
Photo :Camphor/Pramoxine/Zinc
worthwhile Camphor/Pramoxine/Zinc Generic Name: Camphor/Pramoxine/Zinc (KAM for/pram OX een/ZINK) Brand Name: Caladryl Clear, Clear Calamine Overview Side Effects Reviews Q & A More Uses of Camphor/Pramoxine/Zinc: It is used to treat skin irritation. What do I need to tell my doctor BEFORE I take Camphor/Pramoxine/Zinc? If you have an allergy to pramoxine, zinc acetate, or camphor or any other part of camphor/pramoxine/zinc. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. This medicine may interact with other drugs or health problems. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Slideshow Hives: The What, Where, And Why Of This Bizarre Skin Condition What are some things I need to know or do while I take Camphor/Pramoxine/Zinc? Tell all of your health care providers that you take camphor/pramoxine/zinc. This includes your doctors, nurses, pharmacists, and dentists. This medicine may cause harm if swallowed. If this medicine is swallowed, call a doctor or poison control center right away. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using camphor/pramoxine/zinc while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Camphor/Pramoxine/Zinc) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Do not take camphor/pramoxine/zinc by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn). Wash your hands before and after use. Do not wash your hands after use if putting this on your hand. Shake well before use. Clean affected part before use. Make sure to dry well. Put a thin layer on the affected skin and rub in gently. Do not take this medicine for longer than you were told by your doctor. What do I do if I miss a dose? If you use camphor/pramoxine/zinc on a regular basis, put on a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Many times this medicine is used on an as needed basis. Do not use more often than told by the doctor. What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Very bad skin irritation. What are some other side effects of Camphor/Pramoxine/Zinc? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dryness. Itching. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Camphor/Pramoxine/Zinc? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about camphor/pramoxine/zinc, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about camphor/pramoxine/zinc. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using camphor/pramoxine/zinc. Review Date: December 6, 2017 Next Side Effects Print this page Add to My Med List More about pramoxine/zinc acetate topical Side Effects Support Group 0 Reviews Add your own review/rating Drug class: topical anesthetics Consumer resources Other brands: Caladryl Clear , Clear Calamine Related treatment guides Insect Bites Minor Cuts Minor Skin Irritation Poison Ivy ... +3 more Drug Status OTC Availability Over the counter N Pregnancy Category Not classified N/A CSA Schedule Not a controlled drug Pramoxine / zinc acetate topical Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Drug Class Topical anesthetics Related Drugs Skin Rash prednisone , hydrocortisone topical , Deltasone , Westcort , More... Insect Bites benzocaine topical , Lanacane , Dermoplast , Caladryl Clear , Sting Relief , Chiggerex , More... Minor Skin Irritation witch hazel topical , Caladryl Clear , Baza Clear , A+D , More... Poison Ivy Caladryl Clear , More... 3 more conditions... Related: Rash a lot of people


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