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gains Sonahist DM Dosage Generic name: CHLORPHENIRAMINE MALEATE 1mg in 1mL, PHENYLEPHRINE HYDROCHLORIDE 2mg in 1mL, DEXTROMETHORPHAN HYDROBROMIDE 3mg in 1mL Dosage form: oral liquid Side Effects Dosage Professional Interactions Pregnancy More User Reviews Support Group Q & A The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist. Children 6 to under 12 years of age: 2 dropperfuls (2 mL) every 4-6 hours; Children 2 to under 6 years of age: 1 dropperful (1 mL) every 4-6 hours; Children under 2 years of age: As directed by a physician. Next Professional Print this page Add to My Med List More about Sonahist-DM (chlorpheniramine / dextromethorphan / phenylephrine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: upper respiratory combinations Consumer resources Other brands: Ed A-Hist DM , NoHist DM , Norel CS , Zoden DM Drops , ... +12 more Professional resources Sonahist DM (FDA) Other Formulations Sonahist Related treatment guides Cough and Nasal Congestion Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug WADA Class Anti-Doping Classification Drug Class Upper respiratory combinations Related Drugs Cough and Nasal Congestion Promethazine VC with Codeine , Bromfed DM , Mucinex D , Vanacof , Deconex , codeine / phenylephrine / promethazine , Resperal-DM , Vicks NyQuil Severe Cold & Flu , Coricidin HBP Cough & Cold , Vicks Nyquil Cough , Deconex DMX , Crantex , Robitussin Allergy & Cough , Tussin CF , Dimetapp Children's Cold & Cough , Relasin-HC , Mucinex Fast-Max Severe Congestion & Cough , Robitussin Nighttime Cough DM , More... Sonahist-DM Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! you haven't any


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life like Clinac BPO 7 Generic Name: benzoyl peroxide Dosage Form: gel Side Effects Dosage Professional Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here. Clinac BPO 7 (Benzoyl Peroxide Gel USP, 7%) Acne Control Gel Clinac BPO 7 Description Clinac BPO 7 (benzoyl peroxide) is a topical preparation containing 7% benzoyl peroxide as the active ingredient in a gel vehicle containing purified water, propylene glycol, Acrysorb (brand of acrylates copolymer), PEG-400, carbomer 940, disodium EDTA, and sodium hydroxide. The chemical structure for the active ingredient is: benzoyl peroxide C 14 H 10 O 4 (anhydrous) 242.23 Slideshow Newborn Baby Health: 8 Woes From Cradle Cap And Colic To Whooping Cough Clinac BPO 7 - Clinical Pharmacology The exact method of action of benzoyl peroxide in acne vulgaris is not known. Benzoyl Peroxide is an antibacterial agent with demonstrated activity against Propionibacterium acnes . This action combines with the mild keratolytic effect of benzoyl peroxide is believed to be responsible for its usefulness in acne. Little is known about the percutaneous penetration, metabolism and excretion of benzoyl peroxide. Benzoyl peroxide is absorbed by the skin where it is metabolized to benzoic acid and excreted as benzoate in the urine. There is no evidence of systemic toxicity caused by benzoyl peroxide in humans. Indications and Usage for Clinac BPO 7 Clinac BPO 7 is indicated for the topical treatment of mild to moderate acne vulgaris. Contraindications Clinac BPO 7 should not be used in patients who have shown hypersensitivity to benzoyl peroxide or any of the other ingredients in this product. Warnings FOR EXTERNAL USE ONLY. KEEP OUT OF REACH OF CHILDREN. Avoid contact with eyes, eyelids, lips and mucous membranes. If inadvertent contact occurs, rinse area thoroughly with water. Contact with colored material, including fabric and hair, may result in discoloration. When using Clinac BPO 7, avoid unnecessary sun exposure and use a sunscreen. In case of accidental ingestion, seek professional assistance or contact a poison control center immediately. Precautions Information for Patients Avoid contact with eyes, eyelids, lips and mucous membranes. May discolor hair and fabrics. Avoid unnecessary sun exposure and use a sunscreen. Use of oil-free make-up recommended. If severe irritation develops, discontinue use and consult your physician. Carcinogenesis, Mutagenesis and Impairment of Fertility Studies employing a strain of mice that are highly susceptible to developing cancer suggest that benzoyl peroxide act as a tumor promoter. The clinical significance of these finding to humans is not known. Benzoyl peroxide has not been found to be mutagenic (Ames test) and there are no published data indicating that it impairs fertility. Pregnancy: Category C Animal reproductive studies have not been conducted with benzoyl peroxide. It is also not known whether benzoyl peroxide can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Benzoyl peroxide should be used by a pregnant woman only if clearly needed. There are no available data on the effect of benzoyl peroxide on the later growth, development and functional maturation of the unborn child. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when benzoyl peroxide is administered to a nursing woman. Pediatric Use Safety and effectiveness in children below the age of 12 have not been established. Adverse Reactions Allergic contact dermatitis and dryness have been reported with topical benzoyl peroxide therapy. If excessive scaling, erythema or edema occurs, the use of Clinac BPO 7 should be discontinued and appropriate therapy instituted. To hasten resolution of adverse effects, cool compresses may be used. After reaction clears, a reduced dosage schedule may often be resumed if the reaction is judged not to be due to allergenicity. Clinac BPO 7 Dosage and Administration Wash and dry hands, face and affected areas with a gentle cleanser before application. Apply a thin layer of Clinac BPO 7 to the affected area once or twice daily, or as directed by your physician. Replace cap tightly after use. How is Clinac BPO 7 Supplied Clinac BPO 7 Gel 45 gram tube NDC 0496-0857-45 Store at 25 C (77 F); excusions permitted to 15-30 C (59-86 F) [see USP Controlled Room Temperature.]. Rx Only. Ferndale Laboratories, Inc. Ferndale, MI 48220 U.S.A Toll free (888) 548-0900 www.ferndalelabs.com Protected under U.S. Patent. Clinac and Acrysorb are registered trademarks of Dow Pharmaceutical Sciences Corp. Package Label Clinac BPO 7 benzoyl peroxide gel Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0496-0857 Route of Administration TOPICAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength BENZOYL PEROXIDE (BENZOYL PEROXIDE) BENZOYL PEROXIDE 70 mg in 1 g Inactive Ingredients Ingredient Name Strength WATER PROPYLENE GLYCOL POLYETHYLENE GLYCOLS CARBOMER HOMOPOLYMER TYPE C EDETATE DISODIUM SODIUM HYDROXIDE Packaging # Item Code Package Description 1 NDC:0496-0857-45 45 g in 1 TUBE 2 NDC:0496-0857-90 90 g in 1 TUBE 3 NDC:0496-0857-97 1 g in 1 POUCH 4 NDC:0496-0857-98 4 g in 1 TUBE Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 09/12/2000 11/30/2012 Labeler - Ferndale Laboratories, Inc. (005320536) Establishment Name Address ID/FEI Operations Ferndale Laboratories, Inc. 005320536 manufacture Revised: 03/2012 Ferndale Laboratories, Inc. Next Interactions Print this page Add to My Med List More about Clinac BPO (benzoyl peroxide topical) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: topical acne agents Consumer resources Professional resources Benzoyl Peroxide Wash (FDA) Other brands: BenzePro , PanOxyl , Peroderm 7 Wash , Triaz , ... +15 more Related treatment guides Acne Perioral Dermatitis FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Topical acne agents Related Drugs topical acne agents clindamycin topical , erythromycin topical , tretinoin topical , tetracycline topical , dapsone topical , Finacea Acne doxycycline , clindamycin topical , erythromycin topical , minocycline , tretinoin topical , tetracycline , dapsone topical , Accutane , Vibramycin , Retin-A , isotretinoin , More... Perioral Dermatitis metronidazole topical , clindamycin topical , MetroGel , benzoyl peroxide topical , Cleocin T , MetroCream , Noritate , Clindagel , Acne Treatment , MetroLotion , Oxy-10 , Evoclin , More... Clinac BPO Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! and cannot


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is legendary Aplicare Antiseptic Gel Hand Rinse Generic Name: alcohol gel Dosage Form: gel Professional Breastfeeding Reviews More Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies. Drug Facts Alcohol Denat. (anhydrous) 62% Antiseptic For external use only. Keep out of eyes. If contact with eyes occurs, rinse promptly and throughly with water. Flammable. Keep away from fire or flame. Stop use and ask a doctor if significant irritation or sensitization occurs. Keep out of reach of children. In case of accidental ingestion, seek professional assistance or consult a poison control center immediately. Questions or comments? 1-800-760-3236 (Mon to Fri 8:30 AM - 5:00 PM EST) Aplicare Antiseptic Gel Hand Rinse 4 oz Aplicare Antiseptic Gel Hand Rinse antiseptic gel hand rinse gel Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:52380-1614 Route of Administration TOPICAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Alcohol (Alcohol) Alcohol 62 mL in 100 mL Inactive Ingredients Ingredient Name Strength Water Diisopropanolamine FD&C Blue No. 1 FD&C Yellow No. 5 Packaging # Item Code Package Description 1 NDC:52380-1614-2 60 mL in 1 BOTTLE 2 NDC:52380-1614-4 120 mL in 1 BOTTLE 3 NDC:52380-1614-6 480 mL in 1 BOTTLE 4 NDC:52380-1614-0 1.5 mL in 1 PACKET 5 NDC:52380-1614-3 360 mL in 1 BOTTLE Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date OTC monograph not final part333 08/01/2006 Labeler - Aplicare, Inc. (107255002) Establishment Name Address ID/FEI Operations Aplicare, Inc. 058377631 manufacture Revised: 04/2010 Aplicare, Inc. Next Breastfeeding Warnings Print this page Add to My Med List More about Aplicare Antiseptic Gel Hand Rinse (ethanol topical) Breastfeeding 0 Reviews Add your own review/rating Drug class: antiseptic and germicides Professional resources Other brands: Avant Original Fragrance Free , Healing Waters Hand Sanitizer Related treatment guides Topical Disinfection FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status OTC Availability Over the counter N Pregnancy Category Not classified N/A CSA Schedule Not a controlled drug WADA Class Anti-Doping Classification Drug Class Antiseptic and germicides Related Drugs antiseptic and germicides Peridex , chlorhexidine topical , Betadine , Hibiclens , iodine topical , Betadine Aerosol Spray Topical Disinfection Betadine , iodine topical , Betadine Aerosol Spray , povidone iodine topical , Merthiolate , silver nitrate topical , sodium hypochlorite topical , Anasept Antimicrobial , Hysept , Anasept , Anasept Cleanser , Betadine Surgical Scrub , Dakins Full Strength Solution , More... Aplicare Antiseptic Gel Hand Rinse Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! ageing


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Photo :This Mistake Can Cost Athletes' Lives in Cardiac Arrest
issue (*this news item will not be available after 12/18/2017) Tuesday, September 19, 2017 TUESDAY, Sept. 19, 2017 (HealthDay News) -- Athletes are dying from cardiac arrests that occur during play because teammates, coaches and other bystanders don't know how to best save their lives, a new study claims. Cardiopulmonary resuscitation (CPR) applied immediately can give these athletes a fighting chance, but onlookers failed to provide CPR in three out of five cases, according to a review of more than two dozen game videos. Bystanders instead most often tried to keep the athlete from swallowing his or her tongue, acting on the widespread misconception that this must be done to prevent a person in cardiac arrest from asphyxiating, said lead researcher Dana Viskin. She is with the Tel Aviv Sourasky Medical Center and Sackler School of Medicine at Tel Aviv University in Israel. "Athletes, especially professional athletes, are receiving poor CPR because the first responders -- that is, their fellow teammates and medical staff -- are focusing not only on their airway, but specifically on pulling out their tongue, instead of providing chest compressions and fast defibrillation, which is what these players need," Viskin said. While the study focuses on athletes, it likely reveals how onlookers respond to cases of cardiac arrest that occur in average people in the community, said Dr. Peter Kudenchuk. He is a professor of cardiology with the University of Washington School of Medicine in Seattle. "Cardiac arrest in athletes occurs, but it's not very common," Kudenchuk said. "For the rest of us in the United States, a cardiac arrest occurs about once every minute. Half a million lives each year are jeopardized by cardiac arrest, and that's just in the U.S.," he noted. "Often bystanders wither -- doing nothing, not knowing what to do or focusing on the wrong fix," Kudenchuk continued. Viskin and her colleagues decided to investigate the issue after discovering a YouTube video showing the 1990 collapse of Loyola Marymount University basketball player Hank Gathers in the middle of an NCAA game. Gathers, 23, was suffering a cardiac arrest but for two full minutes he received no CPR, the video shows. Shortly afterward, he was pronounced dead at a nearby hospital. The research team searched Google and YouTube for other videos of athletes collapsing during play. They wound up with 29 videos recorded across the globe between 1990 and 2017, involving sports as varied as basketball, soccer, ice hockey, wrestling and volleyball. Nearly two-thirds of the videos (65 percent) showed bystanders taking steps to prevent tongue swallowing. These included placing the player on his side or tilting his head sideways, and reaching into the mouth to pull at the tongue and clear the airway. Only 38 percent of videos showed people performing chest compressions, researchers found. Defibrillators were used in just two cases, and in one of those the first shock did not occur until 10 minutes after the player's collapse. These videos reflect outdated standards for responding to a possible cardiac arrest, Viskin said. In the past, heart experts recommended an "ABC" response to cardiac arrest: airway; breathing; and chest compressions. But in 2010, the American Heart Association reversed course, updating its guidelines to instead recommend a "CAB" approach that emphasizes chest compressions over concerns regarding airway or breathing. Average folks performing CPR now are asked to perform about 100 chest compressions per minute, similar to the beat kept by the disco song "Stayin' Alive," Kudenchuk said. Only people with CPR training should attempt mouth-to-mouth breathing. Viskin said she is concerned that the Gathers video -- which has received nearly 3 million viewings on YouTube -- and other such videos send the wrong message about what should be done during cardiac arrest. "Tongue swallowing is a myth," Viskin said. "The media needs to stop emphasizing the wrong move and start focusing on the right one. Only chest compressions and an automatic defibrillator have been shown to significantly improve survival." When someone collapses, bystanders should use the "No, No, GO!" method to determine whether they should start chest compressions, Kudenchuk wrote in an editorial accompanying the study. First, ask two questions: Is the person conscious? Is the person breathing normally, and not gasping, panting or snoring? "If the answer to those two questions is 'No,' then the smartest and best thing a person can do is start pumping on the chest, because that is a cardiac arrest until proven otherwise," Kudenchuk said. While delivering chest compressions, you should shout out to other people nearby to call 911 and to look for an automatic defibrillator, he said. If there's a defibrillator on hand, follow its instructions to deliver a potentially lifesaving shock to restart the heart. People shouldn't worry at all about whether they're delivering CPR to a person who doesn't need it, Kudenchuk added. "What's the worst thing that can happen? The person wakes up and pushes their rescuer away, and no harm is done," he said. "Don't worry about the mouth or anything else. Put your hands in the middle of the chest and start pumping." The study was published Sept. 19 in the journal Heart Rhythm . SOURCES: Dana Viskin, Tel Aviv Sourasky Medical Center and Sackler School of Medicine at Tel Aviv University, Israel; Peter Kudenchuk, M.D., professor, cardiology, University of Washington School of Medicine, Seattle; Sept. 19, 2017, Heart Rhythm HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Sports Safety Recent Health News different


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emerge as Many New Years resolutions often focus on healthy eating, and one particular diet plan has again drawn praise from medical experts for its ability to help prevent diseases such as diabetes and heart disease the leading cause of death for both men and women, according the Centers for Disease Control and Prevention . For the fifth consecutive year, the Dietary Approaches to Stop Hypertension (DASH) finished atop the Best Overall Diet rankings released earlier this month by U.S. News & World Report . This is the fifth year its panel of nutrition and health experts has released its annual diet analyses. DASH diet guidelines include: Eating plenty of vegetables, fruits, whole grains, lean meats and low-fat dairy; Avoiding red meat, high-fat sweets and snacks; Limiting salt and sodium intake. The DASH diet works by cutting down the sodium, saturated and trans fats, added sugars and cholesterol, said family physician Dhara Patel, D.O. , of Family Healthcare of Rockwall , a Texas Health Physicians Group practice. It still allows for a well-balanced diet and includes all major food groups. By cutting down on these items, it decreases a person s risk of developing high blood pressure and heart disease. Patel said that by following the recommended caloric intake, a person can increase the chances of maintaining or losing weight because the diet is broken down by a person s activity level. It s heart healthy because it decreases the sodium and cholesterol intake, she said. But for optimum cardiovascular benefits, include 30 minutes of exercise. While the diet itself may not prevent type 2 diabetes, maintaining a healthy weight can certainly help prevent and control diabetes. Physicians on the medical staff practice independently and are not employees or agents of the hospital or Texas Health Resources. American Heart Month , Centers for Disease Control and Prevention , DASH Diet , diet , Family Healthcare of Rockwall , fitness , Heart health , Texas Health Physicians Group the reality


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exceptional Ultravate Generic Name: halobetasol topical (HAL oh BAY ta sol) Brand Name: Ultravate, Ultravate X Cream, Ultravate X Ointment Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons What is Ultravate (halobetasol topical)? Halobetasol is a steroid. It reduces the actions of chemicals in the body that cause inflammation. Halobetasol topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Halobetasol topical may also be used for purposes not listed in this medication guide. Slideshow 7 First Aid Kit Must Haves For Your Medicine Cabinet What is the most important information I should know about Ultravate (halobetasol topical)? Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. What should I discuss with my healthcare provider before using Ultravate (halobetasol topical)? You should not use this medicine if you are allergic to halobetasol. To make sure halobetasol topical is safe for you, tell your doctor if you have any type of skin infection. Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether halobetasol topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Halobetasol topical is not approved for use by anyone younger than 12 years old. Do not use halobetasol topical on a child of any age without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. How should I use Ultravate (halobetasol topical)? Do not take by mouth. Halobetasol topical is for use only on the skin. Do not use this medicine on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Wash your hands before and after using halobetasol topical, unless you are using this medicine to treat the skin on your hands. Apply a small amount to the affected area and rub it gently into the skin. Do not apply this medicine over a large area of skin. Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. Covering the treated area can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Call your doctor if your symptoms do not improve after 2 weeks of treatment, or if you develop signs of a bacterial, fungal, or viral skin infection. Store at room temperature away from moisture and heat. What happens if I miss a dose? Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. An overdose of halobetasol topical is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using Ultravate (halobetasol topical)? Rinse with water if this medicine gets in your eyes. Avoid applying this medicine to your face, underarms, or groin area unless your doctor tells you to. Do not use halobetasol topical to treat any skin condition that has not been checked by your doctor. Ultravate (halobetasol topical) side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body. Tell your doctor if you have: weight gain (especially in your face or your upper back and torso); slow wound healing, thinning skin, increased body hair; irregular menstrual periods, changes in sexual function; or muscle weakness, tired feeling, depression, anxiety, feeling irritable. Common side effects may include: stinging or burning where the medicine was applied. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect Ultravate (halobetasol topical)? It is not likely that other drugs you take orally or inject will have an effect on topically applied halobetasol. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Next Side Effects Print this page Add to My Med List More about Ultravate (halobetasol topical) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 6 Reviews Add your own review/rating Generic Availability Drug class: topical steroids Consumer resources Ultravate (Halobetasol Cream and Ointment) Ultravate (Halobetasol Lotion) Ultravate (Advanced Reading) Professional resources Ultravate (FDA) Ultravate Cream (FDA) Other Formulations Ultravate Pack Ointment Ultravate PAC Related treatment guides Atopic Dermatitis Dermatitis Eczema Psoriasis Where can I get more information? Your pharmacist can provide more information about halobetasol topical. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 7.01. Date modified: December 03, 2017 Last reviewed: May 20, 2016 Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Topical steroids Related Drugs Eczema prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , clobetasol topical , More... Psoriasis Humira , methotrexate , cyclosporine , Remicade , adalimumab , infliximab , More... Atopic Dermatitis prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , methylprednisolone , More... Dermatitis fluticasone topical , triamcinolone , hydrocortisone topical , prednisolone , clobetasol topical , More... Ultravate Rating 6 User Reviews 8.1 /10 6 User Reviews 8.1 Rate it! Related Questions & Answers Ultravate - Has this med. been used by anyone in the genital area ? Read more questions listening to


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guidelines All News Consumer Pharma New Drugs Pipeline Clinical Trials FDA Alerts More Health Tip: How a Cochlear Implant Works Print this page -- A cochlear implant is a small, electronic device that when surgically placed under the skin, stimulates the nerve endings in the cochlea to provide a sense of sound to a person who is severely hard of hearing. The U.S. Food and Drug Administration approves of the use of cochlear implants in people aged 1 year and older. The FDA explains how a cochlear implant works: A surgeon places the implant under the skin next to the ear. The implant receives sound from the outside environment, processes it, and sends small electric currents near the auditory nerve. These currents activate the nerve, which then sends a signal to the brain. The brain learns to recognize this signal and the wearer experiences this as "hearing." 2017 HealthDay. All rights reserved. Posted: December 2017 Recommended for you Print this page More News Resources FDA Medwatch Drug Alerts Daily MedNews Pharma Industry News New Drug Approvals New Drug Applications Drug Shortages Clinical Trial Results Generic Drug Approvals Monthly Update Archive Latest Drug Information Updates Ozempic Ozempic (semaglutide) is a glucagon-like peptide-1 (GLP-1) analog administered once-weekly for the treatment... Juluca Juluca (dolutegravir and rilpivirine) is a single-tablet, two-drug regimen of the approved drugs dolutegravir... Hemlibra Hemlibra (emicizumab-kxwh) is a bispecific factor IXa- and factor X-directed antibody indicated to prevent... Prevymis Prevymis (letermovir) a CMV DNA terminase complex inhibitor indicated for prophylaxis of cytomegalovirus... Fasenra Fasenra (benralizumab) is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody indicated... Calquence Calquence (acalabrutinib) is a highly selective, potent, Bruton tyrosine kinase (BTK) inhibitor for the... More drug information updates searching for what you offer


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1st Baron Beaverbrook ClimaraPro Generic Name: Estradiol and Levonorgestrel (es tra DYE ole & LEE voe nor jes trel) Brand Name: ClimaraPro Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Warning Estrogens may raise the chance of endometrial cancer (cancer of the lining of the uterus). Do not use estrogens to prevent heart disease or dementia. Using estrogens may raise the chances of having a heart attack, a stroke, breast cancer, a blood clot, or dementia. Use estrogens with or without progestin for the shortest time needed at the lowest useful dose. Uses of ClimaraPro: It is used to put off soft, brittle bones (osteoporosis) in women after change of life. It is used to prevent or lower the signs of the change of life (menopause). It may be given to you for other reasons. Talk with the doctor. Slideshow A Joint Effort: A Provider's Guide To Orthopedic Pain Options What do I need to tell my doctor BEFORE I take ClimaraPro? If you have an allergy to estradiol, levonorgestrel, or any other part of ClimaraPro (estradiol and levonorgestrel). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any of these health problems: Bleeding disorder, blood clots, a higher risk of having a blood clot, breast cancer, liver problems or liver tumor, heart attack, stroke, or a tumor where estrogen makes it grow. If you have ever had a cancer where hormones make it grow. If you have any of these health problems: Change in the cells lining your uterus, eyesight problems like loss of eyesight due to blood vessel problems in the eye, or migraines. If you have unexplained vaginal bleeding. If you are pregnant or may be pregnant. Do not take this medicine if you are pregnant. If you are breast-feeding or plan to breast-feed. This is not a list of all drugs or health problems that interact with ClimaraPro. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take ClimaraPro? For all uses of ClimaraPro: Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. This medicine may raise the chance of blood clots, a stroke, or a heart attack. Talk with the doctor. Talk with your doctor if you will need to be still for long periods of time like long trips, bedrest after surgery, or illness. Not moving for long periods may raise your chance of blood clots. If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. Have blood work checked as you have been told by the doctor. Talk with the doctor. Have a bone density test as you have been told by your doctor. Talk with your doctor. High blood pressure has happened with drugs like this one. Have your blood pressure checked as you have been told by your doctor. Be sure to have regular breast exams and gynecology check-ups. Your doctor will tell you how often to have these. You will also need to do breast self-exams as your doctor has told you. Talk with your doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take ClimaraPro. Avoid cigarette smoking. Smoking raises the chance of heart disease. Talk with your doctor. Limit your drinking of alcohol. If you drink grapefruit juice or eat grapefruit often, talk with your doctor. Protect patch from the sun. If you are 65 or older, use this medicine with care. You could have more side effects. This medicine is not approved for use in children. Talk with the doctor. Soft, brittle bones (osteoporosis): This medicine works best when used with calcium/vitamin D and weight-bearing workouts like walking or PT (physical therapy). Follow the diet and workout plan that your doctor told you about. How is this medicine (ClimaraPro) best taken? Use ClimaraPro as ordered by your doctor. Read all information given to you. Follow all instructions closely. Put patch on clean, dry, healthy skin on the lower belly or upper buttocks. Move the site with each new patch. Do not place on breast. Place below waistline. Do not put on irritated skin. After you take off a skin patch, be sure to fold the sticky sides of the patch to each other. What do I do if I miss a dose? Put on a missed patch as soon as you think about it after taking off the old one. Do not put on 2 doses or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Chest pain or pressure. Shortness of breath. Coughing up blood. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Swelling, warmth, numbness, change of color, or pain in a leg or arm. Very upset stomach or throwing up. Bulging eyes. Change in how contact lenses feel in the eyes. Change in eyesight, eye pain, or very bad eye irritation. A lump in the breast, breast soreness, or nipple discharge. Breast pain. Vaginal itching or discharge. Vaginal bleeding that is not normal. Low mood (depression). Memory problems or loss. Swelling in the arms or legs. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Very bad skin irritation. What are some other side effects of ClimaraPro? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Hair loss. Back pain. Upset stomach or throwing up. Cramps. Bloating. Swelling. Enlarged breasts. Tender breasts. Vaginal bleeding or spotting. Skin irritation. This medicine may cause dark patches of skin on your face. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out ClimaraPro? Store at room temperature. Store in original container. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take ClimaraPro or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ClimaraPro. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Climara Pro (estradiol / levonorgestrel) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 18 Reviews Add your own review/rating Drug class: sex hormone combinations Consumer resources Climara Pro Climara Pro transdermal Climara Pro (Advanced Reading) Professional resources Climara Pro (FDA) Other Formulations Climara Related treatment guides Postmenopausal Symptoms Prevention of Osteoporosis} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Climara Pro Rating 18 User Reviews 5.2 /10 18 User Reviews 5.2 Rate it! Manufacturer Bayer HealthCare Pharmaceuticals Inc. Drug Class Sex hormone combinations Related Drugs Postmenopausal Symptoms estradiol , Premarin , Estrace , Prempro , conjugated estrogens topical , Climara , Estrogel , Vivelle , Premarin Vaginal , Vivelle-Dot , More... Prevention of Osteoporosis alendronate , Fosamax , Evista , raloxifene , Boniva , Actonel , Reclast , ibandronate , risedronate , zoledronic acid , Duavee , ethinyl estradiol / norethindrone , More...} } try to


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plow through Aplenzin Generic Name: Bupropion Extended-Release Tablets (bue PROE pee on) Brand Name: Aplenzin, Budeprion XL, Forfivo XL, Wellbutrin XL Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Warning Drugs like this one have raised the chance of suicidal thoughts or actions in children and young adults. The risk may be greater in people who have had these thoughts or actions in the past. All people who take Aplenzin (bupropion extended-release tablets) need to be watched closely. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur. Uses of Aplenzin: It is used to treat low mood (depression). It is used to treat seasonal affective disorder (SAD). It may be given to you for other reasons. Talk with the doctor. Slideshow 8 Reasons Why Obesity Needs To Be Tackled Now What do I need to tell my doctor BEFORE I take Aplenzin? If you have an allergy to bupropion or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have ever had seizures. If you drink a lot of alcohol and you stop drinking all of a sudden. If you use certain other drugs like drugs for seizures or anxiety and you stop using them all of a sudden. If you have ever had an eating problem like anorexia or bulimia. If you have any of these health problems: Kidney disease or liver disease. If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking Aplenzin within 14 days of those drugs can cause very bad high blood pressure. If you are taking any of these drugs: Linezolid or methylene blue. If you are taking another drug that has the same drug in it. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Aplenzin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Aplenzin? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how Aplenzin affects you. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine. Do not stop taking Aplenzin all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop this medicine, you will want to slowly stop it as ordered by your doctor. High blood pressure has happened with Aplenzin. Have your blood pressure checked as you have been told by your doctor. This medicine may raise the chance of seizures. The chance may be higher in people who have certain health problems, use certain other drugs, or drink a lot of alcohol. Talk to your doctor to see if you have a greater chance of seizures while taking this medicine. Avoid drinking alcohol while taking Aplenzin. Talk with your doctor before you use other drugs and natural products that slow your actions. It may take several weeks to see the full effects. Some people may have a higher chance of eye problems with this medicine. Your doctor may want you to have an eye exam to see if you have a higher chance of these eye problems. Call your doctor right away if you have eye pain, change in eyesight, or swelling or redness in or around the eye. If you are taking digoxin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with Aplenzin (bupropion extended-release tablets). This medicine is not approved for use in children. Talk with the doctor. If you are 65 or older, use this medicine with care. You could have more side effects. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Aplenzin while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. If you smoke: Not all products are approved for use to help stop smoking. Talk with the doctor to make sure that you have the right product. New or worse mental, mood, or behavior problems have happened when bupropion has been used to stop smoking. These problems include thoughts of suicide or killing someone else, depression, forceful actions, fury, anxiety, and anger. These problems have happened in people with and without a history of mental or mood problems. Talk with the doctor. How is this medicine (Aplenzin) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Do not take Aplenzin more often than you are told. This may raise the risk of seizures. Be sure you know how far apart to take your doses. Take in the morning if taking once a day. Take with or without food. If you are not able to sleep, do not take this medicine too close to bedtime. Talk with your doctor. Swallow whole. Do not chew, break, or crush. To gain the most benefit, do not miss doses. Keep taking Aplenzin as you have been told by your doctor or other health care provider, even if you feel well. If you have trouble swallowing, talk with your doctor. What do I do if I miss a dose? Skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Change in how you act. Feeling confused. Hallucinations (seeing or hearing things that are not there). If seizures are new or worse after starting this medicine. A big weight gain or loss. Chest pain or pressure or a fast heartbeat. A heartbeat that does not feel normal. Swelling. Shortness of breath. Ringing in ears. Passing urine more often. Swollen gland. Trouble moving around. Very bad muscle or joint pain. A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. What are some other side effects of Aplenzin? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dizziness. Headache. Belly pain. Shakiness. Feeling nervous and excitable. Strange or odd dreams. Upset stomach or throwing up. Hard stools (constipation). Gas. Dry mouth. Not able to sleep. Muscle or joint pain. Nose or throat irritation. Sweating a lot. Not hungry. A change in weight without trying. For some brands, you may see the tablet shell in your stool. For these brands, this is normal and not a cause for concern. If you have questions, talk with your doctor. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Aplenzin? Store at room temperature. Protect from light. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Aplenzin is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take Aplenzin or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Aplenzin. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Aplenzin (bupropion) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 9 Reviews Add your own review/rating Drug class: miscellaneous antidepressants Consumer resources Aplenzin Aplenzin (Advanced Reading) Other brands: Wellbutrin , Wellbutrin XL , Buproban , Wellbutrin SR , ... +4 more Professional resources Aplenzin (FDA) Bupropion Hydrochloride (AHFS Monograph) Related treatment guides Depression Major Depressive Disorder} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA WADA Class Anti-Doping Classification Aplenzin Rating 9 User Reviews 7.5 /10 9 User Reviews 7.5 Rate it! Manufacturer Valeant Pharmaceuticals International, Inc. Drug Class Miscellaneous antidepressants Related Drugs Major Depressive Disorder trazodone , sertraline , Zoloft , Lexapro , Cymbalta , Prozac , Wellbutrin , fluoxetine , venlafaxine , bupropion , duloxetine , escitalopram , More... Depression trazodone , sertraline , Xanax , citalopram , Zoloft , Lexapro , Cymbalta , Celexa , Prozac , Wellbutrin , alprazolam , fluoxetine , More... Aplenzin Images Aplenzin 348 mg (BR 348 ) View all images Related: Major Depression} } anxious train


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began (*this news item will not be available after 12/18/2017) By Robert Preidt Tuesday, September 19, 2017 TUESDAY, Sept. 19, 2017 (HealthDay News) -- Besides the toll in deaths and disability, hospitalizations linked to gun injuries cost U.S. taxpayers hundreds of millions of dollars a year, a new study finds. A University of Iowa analysis of nationwide data on hospital admissions between 2003 and 2013 identified 336,785 for gun injuries. That's more than 30,000 a year, on average. More than 60 percent of gun injuries resulted from assaults, according to the study. Of those, 70 percent were caused by handguns. In all, 23 percent of gun injuries were accidental and 9 percent were self-inflicted. Hospitalization costs for gun injuries during the study period topped $622 million a year. While that's less than 1 percent of the $377 billion spent each year for hospital stays, gun injuries are often more costly to treat, researchers said. Average cost of a typical hospital stay was $10,400, compared with $17,000 to $33,400 for a gun injury. Injuries from assault weapons were most costly to treat, at more than $32,000 each. The burden fell heavily on taxpayers and the health care system. The study found 57 percent of gun injury hospitalization costs (more than $205 million) were either paid by Medicaid or not paid at all ($155 million). "Efforts to prevent these injuries, particularly assaults and injuries caused by handguns, could reduce this cost burden," lead author Corinne Peek-Asa said in a university news release. She is a professor of environmental and occupational health. The study also found that more than 80 percent of patients hospitalized for gun injuries were between 15 and 44 years old. The highest rate was among 15- to 24-year-olds (28.9 per 100,000). The rate for males was 18.2 per 100,000, compared with 2.1 per 100,000 for females. The injury rate for blacks was 39.7 per 100,000, compared to 4.4 for whites and 21.1 per 100,000 for other groups. The study was published recently in the journal Injury Epidemiology . SOURCE: University of Iowa, news release, Sept. 5, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Gun Safety Health Statistics Recent Health News sizable of style


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most unlikely Planning to go the full 26.2? Running USA estimates that a record 541,000 people finished marathons in the United States in 2013, a significant increase from the 353,000 who finished the 26.2-mile trek in 2000. With the right training, you, too, can join this growing trend. But where do you start? Marathon Training Shouldn t Be a Sprint If you already run 15 to 20 miles a week, you should start training approximately four months before the marathon. Most marathon training schedules include one long run and a few shorter runs each week. Mike Macko, P.T., D.P.T., O.C.S., M.T.C., physical therapy manager at Texas Health Ben Hogan Sports Medicine , says to be wary of schedules that push you too hard, too fast. Safe programs won t increase the long run or total mileage more than about 10 to 15 percent from one week to the next, Macko says. Make sure your program has you increasing distance for three to four weeks, then decreasing slightly every fourth or fifth week. Trust Your Taper Macko has run six marathons himself, including the Dallas Marathon , in which he set a personal best time of three hours and 17 minutes. He says first-time marathoners should focus on finishing strong, not worrying about time. A common mistake among beginners is overdoing it before the marathon. Rest days are important because you re training your body to do something it has never done before, Macko says. Your bones, muscles, tendons and ligaments will adapt to the stress you put on them, but it takes time. Macko s most important advice is to trust your taper. Do your longest run three to four weeks before the marathon, then taper down, Macko says. There s nothing you can do the last few weeks that is going to increase your readiness. How to Choose Your Shoes Serious runners should never pick a running shoe based solely on the shoe s appearance. Instead, you should get professionally fitted for running shoes and select the shoe that s right for your foot and body type. The brand you choose shouldn t matter as much as the shoe s design. Cushioned shoes are for runners with high-arched, rigid feet. Stabilizing shoes are for runners whose arches collapse while running. Runners with severely pronated feet may benefit most from motion-controlling shoes. If you weigh 150 pounds, the American Academy of Orthopaedic Surgeons recommends replacing your shoes after 500 miles. Since many marathon training programs exceed this mileage, you may want to buy two pairs of the same shoe and switch to the second pair several weeks before your race. Ben Hogan Sports Medicine can help you meet your running goals. Visit TexasHealth.org/BenHogan to learn more. Dallas Marathon , marathon , marathon training , running , running shoes , Texas Health Ben Hogan modern


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in good shape Visipaque Generic Name: iodixanol (EYE oh DIX an ol) Brand Name: Visipaque Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons What is Visipaque (iodixanol)? Iodixanol is in a group of drugs called radiopaque (RAY dee oh payk) contrast agents. Iodixanol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination. Iodixanol is used to help diagnose certain disorders of the brain, blood vessels, heart, kidneys, and other internal organs. Iodixanol may also be used for purposes not listed in this medication guide. Slideshow Sexual Health Q+A: Your Questions Answered What is the most important information I should know about Visipaque (iodixanol)? Iodixanol should not be given to a child who has recently used a laxative (stool softener) or has not eaten properly. What should I discuss with my healthcare provider before receiving Visipaque (iodixanol)? Iodixanol should not be given to a child who has recently used a laxative (stool softener) or has not eaten properly. Tell your doctor if you have ever had any type of reaction to another contrast agent. To make sure iodixanol is safe for you, tell your doctor if you have: liver or kidney disease; heart disease, including congestive heart failure; a history of stroke, blood clots, or coronary artery disease; asthma, food or drug allergies; epilepsy or other seizure disorder; sickle cell anemia; diabetes; an active infection; a weak immune system (caused by disease or by using certain medicine); an autoimmune disorder such as rheumatoid arthritis, lupus, or psoriasis; pheochromocytoma (tumor of the adrenal gland); multiple myeloma (bone cancer); or thyroid disorder, including cancer. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether iodixanol passes into breast milk or if it could affect the nursing baby. You should not breast-feed within 10 hours after receiving iodixanol. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. How is Visipaque (iodixanol)used? Iodixanol is injected into a vein through an IV. A healthcare provider will give you this injection just before your radiologic test. You may be given medication to prevent certain side effects while you are receiving iodixanol. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when iodixanol is injected. Drink extra fluids before and after your radiologic test. Iodixanol can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test. Older adults may need special care to avoid becoming dehydrated. Your kidney function may need to be checked after you have received iodixanol. Iodixanol can interfere with certain medical tests for up to 16 days after you are treated with this medicine. Tell any doctor who treats you that you have recently received iodixanol. Iodixanol can make radioactive iodine less effective in people with thyroid cancer. This effect can last for up to 8 weeks after you receive iodixanol. Tell your doctor if you are scheduled to be treated with radioactive iodine I-131 or I-123. What happens if I miss a dose? Since iodixanol is used only during your radiologic test, you will not be on a dosing schedule. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while receiving Visipaque (iodixanol)? Do not allow yourself to become dehydrated during the first few days after receiving iodixanol. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor's instructions about the types and amount of fluids you should drink. Visipaque (iodixanol) side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Call your doctor at once if you have: a light-headed feeling, like you might pass out; swelling, rapid weight gain, little or no urinating; wheezing or trouble breathing; a seizure (convulsions); thyroid symptoms--extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain; heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; or signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood. Common side effects may include: pain or warm feeling when the medicine is injected; dizziness, spinning sensation; numbness or tingly feeling; vision changes; sleep problems (insomnia); headache, migraine; chest pain; nausea, vomiting, diarrhea; agitation, anxiety, nervousness; skin rash, itching; or changes in your sense of taste or smell. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect Visipaque (iodixanol)? Tell your doctor about all your current medicines, especially: metformin (Glucophage, Glucovance, Actoplus Met, PrandiMet, Avandamet, Kombiglyze, Janumet, Kazano, Invokamet, Jentadueto, Xigduo, Synjardy, Metaglip, and others). This list is not complete. Other drugs may interact with iodixanol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Next Side Effects Print this page Add to My Med List More about Visipaque (iodixanol) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: non-ionic iodinated contrast media Consumer resources Visipaque Visipaque (Advanced Reading) Professional resources Visipaque (FDA) Related treatment guides Computed Tomography Aortography Cerebral Arteriography Coronary Arteriography ... +5 more Where can I get more information? Your doctor or pharmacist can provide more information about iodixanol. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 3.03. Date modified: December 03, 2017 Last reviewed: November 13, 2017} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Drug Class Non-ionic iodinated contrast media Related Drugs Cerebral Arteriography iohexol , Omnipaque 300 , ioversol , Omnipaque 350 , iodixanol , iopromide , More... Peripheral Arteriography ioversol , iodixanol , iopromide , Optiray 300 , Optiray 320 , Ultravist , More... Coronary Arteriography ioversol , iodixanol , iopromide , Optiray 300 , Optiray 320 , Ultravist , More... Intra-arterial Digital Subtraction Angiography ioversol , iodixanol , iopromide , Optiray 320 , Optiray 300 , Ultravist , More... 5 more conditions... Visipaque Rating No Reviews - Be the first! 10 /10 No Reviews - Be the first! 10 Rate it! Related Questions & Answers How much visipaque effect for angioplasty surgery? Read more questions} } this kind of


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step by step Romazicon Generic Name: flumazenil (floo MAZ e nil) Brand Name: Romazicon Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Compare Alternatives What is Romazicon (flumazenil)? Flumazenil reverses the effects of benzodiazepine (BENZ-oh-dye-AYZ-e-peen) sedatives such as Valium, Versed, Xanax, Tranxene, and others. Benzodiazepines are sometimes used as sedatives before surgery or other medical procedures. Flumazenil is used to reverse benzodiazepine sedation to help you wake up after your medical procedure. Flumazenil is also used to treat benzodiazepine overdose in adults. Flumazenil may also be used for purposes not listed in this medication guide. Slideshow Looking Ahead: New Drug Approvals for 2017 What is the most important information I should know about Romazicon (flumazenil)? Flumazenil may cause seizures (convulsions), especially in people who have sedative-addiction withdrawal symptoms or recent antidepressant overdose, people who have recently received injectable benzodiazepines, or people who had symptoms of a seizure just before receiving flumazenil. Talk to your doctor if you have concerns about the risk of seizure. What should I discuss with my health care provider before receiving Romazicon (flumazenil)? Flumazenil may cause seizures (convulsions), especially: in people withdrawing from sedative addiction; in people who have recently taken an antidepressant overdose; in people who have recently received injectable benzodiazepines; or in people who had seizure-like symptoms just before receiving flumazenil. Talk to your doctor if you have concerns about the risk of seizure. You should not receive this medication if you are allergic to flumazenil or any type of benzodiazepine sedative, or if you have taken an overdose of certain antidepressant medication. To make sure flumazenil is safe for you, tell your doctor if you have: epilepsy or other seizure disorder (especially if you take a benzodiazepine to treat seizures); a history of head injury; any type of breathing problem or lung disease; liver disease; panic or anxiety disorder; a history of alcoholism or drug addiction; or if you have been using benzodiazepine long-term. FDA pregnancy category C. It is not known whether flumazenil will harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether flumazenil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How is Romazicon (flumazenil)given? Flumazenil is injected into a vein through an IV. A healthcare provider will give you this injection. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when flumazenil is injected. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely after you receive flumazenil. You may have temporary amnesia while you are waking up from sedation. You may not remember everything going on around you for up to 2 hours. What happens if I miss a dose? Because you will receive flumazenil in a clinical setting, you are not likely to miss a dose. What happens if I overdose? Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. What should I avoid after receiving Romazicon (flumazenil)? This medication may impair your thinking or reactions. For at least 24 hours after you leave the hospital or surgery center, do not drive or do anything else that requires you to be awake and alert. Continue to limit these activities until you no longer feel sedated (weak, drowsy, or dizzy). Do not drink alcohol for at least 24 hours after receiving flumazenil, or if you still feel sedated. Also avoid taking any over-the-counter medications for at least 24 hours, especially if you still feel sedated after receiving flumazenil. Even though you may feel alert after waking up from sedation, your judgment or reactions may still be impaired. Follow your caregivers' instructions about how long to limit your activities. Romazicon (flumazenil) side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregiver right away if you have: agitation, tremors, feeling suddenly hot; chest pain and severe dizziness, rapid pulse, fast or pounding heartbeats; or a light-headed feeling, like you might pass out. Common side effects may include: nausea, vomiting; headache, mild dizziness; flushing (warmth, redness, or tingly feeling); increased sweating; blurred vision; or pain where the medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect Romazicon (flumazenil)? Receiving flumazenil after taking large doses of certain antidepressants can cause dangerous or life-threatening side effects. Tell your doctor before you receive flumazenil if you have recently taken an antidepressant such as amitriptyline, doxepin, clomipramine, desipramine, imipramine, or nortriptyline. Other drugs may interact with flumazenil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Next Side Effects Print this page Add to My Med List More about Romazicon (flumazenil) Side Effects During Pregnancy Dosage Information Drug Interactions Compare Alternatives Support Group En Español 0 Reviews Add your own review/rating Drug class: antidotes Professional resources Romazicon (AHFS Monograph) Romazicon (FDA) Related treatment guides Reversal of Sedation Benzodiazepine Overdose Where can I get more information? Your doctor or pharmacist can provide more information about flumazenil. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01. Date modified: December 03, 2017 Last reviewed: December 13, 2013 Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Antidotes Related Drugs Benzodiazepine Overdose flumazenil , More... Reversal of Sedation flumazenil , More... Romazicon Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the Romazicon support group to connect with others who have similar interests. abruptly


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have the ability Ultravate Cream Generic Name: halobetasol propionate Dosage Form: cream Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons Ultravate (halobetasol propionate cream) Cream, 0.05% For Dermatological Use Only. Not for Ophthalmic Use. Rx only Ultravate Cream Description Ultravate (halobetasol propionate cream) Cream, 0.05% contains halobetasol propionate, a synthetic corticosteroid for topical dermatological use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and antipruritic agent. Chemically halobetasol propionate is 21-chloro-6α, 9-difluoro-11β, 17-dihydroxy-16β-methylpregna-1, 4-diene-3-20-dione, 17-propionate, C 25 H 31 ClF 2 O 5 . It has the following structural formula: Halobetasol propionate has the molecular weight of 485. It is a white crystalline powder insoluble in water. Each gram of Ultravate Cream contains 0.5 mg/g of halobetasol propionate in a cream base of cetyl alcohol, glycerin, isopropyl isostearate, isopropyl palmitate, steareth-21, diazolidinyl urea, methylchloroisothiazolinone, (and) methylisothiazolinone and water. Slideshow Prednisone: 12 Things You Should Know Ultravate Cream - Clinical Pharmacology Like other topical corticosteroids, halobetasol propionate has anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of the anti-inflammatory activity of the topical corticosteroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A 2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A 2 . Pharmacokinetics The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier. Occlusive dressings with hydrocortisone for up to 24 hours have not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption. Human and animal studies indicate that less than 6% of the applied dose of halobetasol propionate enters the circulation within 96 hours following topical administration of the cream. Studies performed with Ultravate Cream indicate that it is in the super-high range of potency as compared with other topical corticosteroids. Indications and Usage for Ultravate Cream Ultravate Cream 0.05% is a super-high potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Treatment beyond two consecutive weeks is not recommended, and the total dosage should not exceed 50 g/week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in children under 12 years of age is not recommended. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary. Contraindications Ultravate Cream is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation. Precautions General Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment. Manifestations of Cushing s syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment. Patients applying a topical steroid to a large surface area or to areas under occlusion should be evaluated periodically for evidence of HPA axis suppression. This may be done by using the ACTH stimulation, A.M. plasma cortisol, and urinary free-cortisol tests. Patients receiving super potent corticosteroids should not be treated for more than 2 weeks at a time and only small areas should be treated at any one time due to the increased risk of HPA suppression. Ultravate Cream produced HPA axis suppression when used in divided doses at 7 grams per day for one week in patients with psoriasis. These effects were reversible upon discontinuation of treatment. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent corticosteroid. Recovery of HPA axis function is generally prompt upon discontinuation of topical corticosteroids. Infrequently, signs and symptoms of glucocorticosteroid insufficiency may occur requiring supplemental systemic corticosteroids. For information on systemic supplementation, see prescribing information for those products. Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios (see PRECAUTIONS : Pediatric Use ). If irritation develops, Ultravate Cream should be discontinued and appropriate therapy instituted. Allergic contact dermatitis with corticosteroids is usually diagnosed by observing failure to heal rather than noting a clinical exacerbation as with most topical products not containing corticosteroids. Such an observation should be corroborated with appropriate diagnostic patch testing. If concomitant skin infections are present or develop, an appropriate antifungal or antibacterial agent should be used. If a favorable response does not occur promptly, use of Ultravate Cream should be discontinued until the infection has been adequately controlled. Ultravate Cream should not be used in the treatment of rosacea or perioral dermatitis, and it should not be used on the face, groin, or in the axillae. Information for Patients Patients using topical corticosteroids should receive the following information and instructions: The medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes. The medication should not be used for any disorder other than that for which it was prescribed. The treated skin area should not be bandaged, otherwise covered or wrapped, so as to be occlusive unless directed by the physician. Patients should report to their physician any signs of local adverse reactions. Laboratory Tests The following tests may be helpful in evaluating patients for HPA axis suppression: ACTH-stimulation test; A.M. plasma cortisol test; Urinary free-cortisol test. Carcinogenesis, Mutagenesis, and Impairment of Fertility Long-term animal studies have not been performed to evaluate the carcinogenic potential of halobetasol propionate. Positive mutagenicity effects were observed in two genotoxicity assays. Halobetasol propionate was positive in a Chinese hamster micronucleus test, and in a mouse lymphoma gene mutation assay in vitro . Studies in the rat following oral administration at dose levels up to 50 µg/kg/day indicated no impairment of fertility or general reproductive performance. In other genotoxicity testing, halobetasol propionate was not found to be genotoxic in the Ames/Salmonella assay, in the sister chromatid exchange test in somatic cells of the Chinese hamster, in chromosome aberration studies of germinal and somatic cells of rodents, and in a mammalian spot test to determine point mutations. Pregnancy Teratogenic effects: Pregnancy Category C Corticosteroids have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. Halobetasol propionate has been shown to be teratogenic in SPF rats and chinchilla-type rabbits when given systemically during gestation at doses of 0.04 to 0.1 mg/kg in rats and 0.01 mg/kg in rabbits. These doses are approximately 13, 33 and 3 times, respectively, the human topical dose of Ultravate Cream. Halobetasol propionate was embryotoxic in rabbits but not in rats. Cleft palate was observed in both rats and rabbits. Omphalocele was seen in rats, but not in rabbits. There are no adequate and well-controlled studies of the teratogenic potential of halobetasol propionate in pregnant women. Ultravate Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Ultravate Cream is administered to a nursing woman. Pediatric Use Safety and effectiveness of Ultravate Cream in pediatric patients have not been established and use in pediatric patients under 12 is not recommended. Because of a higher ratio of skin surface area to body mass, pediatric patients are at a greater risk than adults of HPA axis suppression and Cushing s syndrome when they are treated with topical corticosteroids. They are therefore also at greater risk of adrenal insufficiency during or after withdrawal of treatment. Adverse effects including striae have been reported with inappropriate use of topical corticosteroids in infants and children. HPA axis suppression, Cushing s syndrome, linear growth retardation, delayed weight gain and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include low plasma cortisol levels and an absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema. Geriatric Use Of approximately 400 patients treated with Ultravate Cream in clinical studies, 25% were 61 years and over and 6% were 71 years and over. No overall differences in safety or effectiveness were observed between these patients and younger patients; and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Adverse Reactions In controlled clinical trials, the most frequent adverse events reported for Ultravate Cream included stinging, burning or itching in 4.4% of the patients. Less frequently reported adverse reactions were dry skin, erythema, skin atrophy, leukoderma, vesicles and rash. The following additional local adverse reactions are reported infrequently with topical corticosteroids, and they may occur more frequently with high potency corticosteroids, such as Ultravate Cream. These reactions are listed in an approximate decreasing order of occurrence: folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, striae and miliaria. Overdosage Topically applied Ultravate Cream can be absorbed in sufficient amounts to produce systemic effects (see PRECAUTIONS ). Ultravate Cream Dosage and Administration Apply a thin layer of Ultravate Cream to the affected skin once or twice daily, as directed by your physician, and rub in gently and completely. Ultravate (halobetasol propionate cream) Cream is a super-high potency topical corticosteroid; therefore, treatment should be limited to two weeks, and amounts greater than 50 g/wk should not be used. As with other corticosteroids, therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Ultravate Cream should not be used with occlusive dressings. How is Ultravate Cream Supplied Ultravate (halobetasol propionate cream) Cream, 0.05% is supplied in the following tube sizes: 15 g (NDC 10631-103-15) 50 g (NDC 10631-103-50) STORAGE Store between 15 C and 30 C (59 F and 86 F). RANBAXY Jacksonville, FL 32257 USA 09-0085 (Flat), 09-0086 (Folded) Revised May 2010 PACKAGE LABEL.PRINCIPAL DISPLAY PANEL 15 gram container label 15 gram carton label 50 gram container label 50 gram carton label ULTRAVATE halobetasol propionate cream Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:10631-103 Route of Administration TOPICAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength HALOBETASOL PROPIONATE (HALOBETASOL) HALOBETASOL PROPIONATE 0.5 mg in 1 g Inactive Ingredients Ingredient Name Strength STEARETH-21 DIAZOLIDINYL UREA METHYLCHLOROISOTHIAZOLINONE CETYL ALCOHOL GLYCERIN ISOPROPYL PALMITATE METHYLISOTHIAZOLINONE WATER Packaging # Item Code Package Description 1 NDC:10631-103-15 15 g in 1 TUBE 2 NDC:10631-103-50 50 g in 1 TUBE Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date NDA NDA019967 03/16/2009 Labeler - Ranbaxy Laboratories Inc. (169932519) Registrant - Ranbaxy Laboratories Inc. (169932519) Establishment Name Address ID/FEI Operations Contract Pharmaceuticals Limited 248761249 manufacture Revised: 05/2011 Ranbaxy Laboratories Inc. Next Interactions Print this page Add to My Med List More about Ultravate (halobetasol topical) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 6 Reviews Add your own review/rating Generic Availability Drug class: topical steroids Consumer resources Ultravate ... +3 more Professional resources Ultravate (FDA) Other brands: Halonate Other Formulations Ultravate Pack Ointment Ultravate PAC Related treatment guides Atopic Dermatitis Dermatitis Eczema Psoriasis} FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Topical steroids Related Drugs topical steroids fluticasone topical , triamcinolone topical , hydrocortisone topical , clobetasol topical Eczema prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , clobetasol topical , More... Psoriasis Humira , methotrexate , cyclosporine , Remicade , adalimumab , infliximab , More... Atopic Dermatitis prednisone , fluticasone topical , triamcinolone topical , hydrocortisone topical , dexamethasone , methylprednisolone , More... 1 more conditions... Ultravate Rating 6 User Reviews 8.1 /10 6 User Reviews 8.1 Rate it!} } incapability


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