exercise Aplenzin (Oral) Generic Name: bupropion (Oral route) bue-PROE-pee-on Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Oral route(Tablet;Tablet, Extended Release) Suicidality and Antidepressant DrugsAlthough Zyban(R) is not indicated for treatment of depression, it contains the same active ingredient as the antidepressant medications Wellbutrin(R), Wellbutrin(R) SR, and Wellbutrin XL(R) . Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects over age 24; there was a reduction in risk with antidepressant use in subjects aged 65 and older. In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber BuPROPion hydrochloride extended-release tablet is not approved for use in pediatric patients . Oral route(Tablet, Extended Release) Suicidality and Antidepressant DrugsAntidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects aged 65 and older .In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber . Commonly used brand name(s) In the U.S. Aplenzin Budeprion SR Budeprion XL Buproban Forfivo XL Wellbutrin Wellbutrin SR Wellbutrin XL Zyban Available Dosage Forms: Tablet, Extended Release, 24 HR Tablet, Extended Release, 12 HR Tablet Tablet, Extended Release Therapeutic Class: Antidepressant Chemical Class: Aminoketone Slideshow Women's Health: Separating Fact From Fiction Uses For Aplenzin Bupropion is used to treat depression and to prevent depression in patients with seasonal affective disorder (SAD), which is sometimes called winter depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names. If you are already taking medicine for depression or to help you stop smoking, discuss this with your doctor before taking bupropion. It is very important that you receive only one prescription at a time for bupropion. This medicine is available only with your doctor's prescription. Before Using Aplenzin In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of bupropion in the pediatric population. However, children are more sensitive to the effects of this medicine than adults when used for treating depression. Use of bupropion to treat depression in children is not recommended. Safety and efficacy of bupropion to help stop smoking have not been established in children. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bupropion in the elderly. However, elderly patients may be more sensitive to the effects of this medicine and are more likely to have age-related kidney or liver problems, which may require caution and an adjustment in the dose for patients receiving bupropion. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Bromopride Furazolidone Iproniazid Isocarboxazid Linezolid Methylene Blue Metoclopramide Moclobemide Nialamide Phenelzine Procarbazine Rasagiline Selegiline Tranylcypromine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acetophenazine Aclidinium Acrivastine Alcaftadine Amantadine Ambenonium Amdinocillin Amdinocillin Pivoxil Amiloride Amineptine Aminophylline Amitriptyline Amitriptylinoxide Amoxapine Amphetamine Ampicillin Anisotropine Antazoline Aripiprazole Astemizole Atomoxetine Atropine Azatadine Azelastine Azlocillin Bacampicillin Belladonna Alkaloids Benperidol Benzphetamine Bepotastine Betamethasone Brexpiprazole Bromodiphenhydramine Bromperidol Brompheniramine Buclizine Budesonide Bupivacaine Butriptyline Butylscopolamine Carbamazepine Carbenicillin Carbimazole Carbinoxamine Carvedilol Chlorambucil Chlorotrianisene Chlorpheniramine Chlorphenoxamine Cimetidine Cimetropium Cinnarizine Citalopram Clemastine Clemizole Clidinium Clobetasone Clomipramine Clopidogrel Cloxacillin Clozapine Codeine Conjugated Estrogens Corticotropin Cortisone Cosyntropin Cyclacillin Cyclizine Cyclosporine Cyproheptadine Danazol Darifenacin Deflazacort Delavirdine Demecarium Desipramine Desonide Desvenlafaxine Deutetrabenazine Dexamethasone Dexbrompheniramine Dexchlorpheniramine Dextroamphetamine Dextromethorphan Dibenzepin Dicloxacillin Dicyclomine Dienestrol Diethylstilbestrol Dimenhydrinate Diphenhydramine Diphenylpyraline Distigmine Donepezil Dopamine Dothiepin Doxepin Doxorubicin Doxorubicin Hydrochloride Liposome Doxylamine Droperidol Duloxetine Ebastine Echothiophate Edrophonium Efavirenz Eliglustat Emedastine Enflurane Epinastine Escitalopram Esterified Estrogens Estradiol Estramustine Estriol Estrone Estropipate Ethinyl Estradiol Famotidine Fesoterodine Flavoxate Flecainide Floxacillin Fludrocortisone Flunarizine Flunisolide Fluoxetine Fluticasone Fluvoxamine Fosphenytoin Galantamine Glycopyrrolate Guanidine Haloperidol Hetacillin Homatropine Hydrocortisone Hydroxyzine Hyoscyamine Imipramine Indalpine Iobenguane I 123 Isoflurophate Isoniazid Isopropamide Ketamine Ketotifen Levocabastine Levodopa Levomilnacipran Lidocaine Lindane Lisdexamfetamine Lofepramine Lopinavir Loxapine Mebeverine Mebhydrolin Meclizine Memantine Mepenzolate Mestranol Metformin Methamphetamine Methantheline Methdilazine Methenolone Methicillin Methimazole Methixene Methylphenidate Methylprednisolone Methyltestosterone Metronidazole Mexiletine Mezlocillin Milnacipran Mizolastine Nafcillin Nalidixic Acid Nandrolone Nebivolol Nefazodone Neostigmine Niaprazine Nortriptyline Olopatadine Ondansetron Opipramol Ospemifene Oxacillin Oxaliplatin Oxandrolone Oxatomide Oxybutynin Oxymetholone Paramethasone Paroxetine Penicillin G Penicillin V Phenindamine Pheniramine Phenobarbital Phenyltoloxamine Phenytoin Physostigmine Pimozide Pinaverium Pindolol Piperacillin Pirenzepine Pivampicillin Pizotyline Polyestradiol Phosphate Prasugrel Prednisolone Prednisone Procainamide Procaine Promestriene Promethazine Propafenone Propantheline Propicillin Propiverine Propizepine Propranolol Protriptyline Pyrilamine Quinestrol Ranitidine Regorafenib Rimexolone Risperidone Ritonavir Rivastigmine Scopolamine Sertraline Sibutramine Solifenacin Sorafenib Stanozolol Sultamicillin Tacrine Terfenadine Testosterone Theophylline Thioridazine Thiotepa Thonzylamine Tibolone Ticarcillin Ticlopidine Timiperone Tiotropium Tolterodine Tramadol Trimeprazine Trimipramine Tripelennamine Triprolidine Tropicamide Trospium Umeclidinium Valbenazine Valethamate Varenicline Venlafaxine Vortioxetine Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aripiprazole Lauroxil Digoxin Isavuconazonium Sulfate St John's Wort Tipranavir Zolpidem Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Alcohol use, if stopped suddenly, or Eating disorders (eg, anorexia, bulimia), history of or Seizures, history of or Seizure medicine use, if stopped suddenly (eg, carbamazepine (Tegretol ), phenobarbital, phenytoin (Dilantin )), or Sleeping or anxiety medicine use, if stopped suddenly (eg, alprazolam (Xanax ), lorazepam (Ativan ), temazepam (Restoril ), triazolam (Halcion )) Should not be used in patients with these conditions. Arteriovenous malformation (circulation problem) or Brain tumor or infection or Diabetes or Drug or alcohol abuse or Head injury, severe or Hypoglycemia (low blood sugar) or Hyponatremia (low sodium in the blood) or Hypoxia (low oxygen in the blood) or Liver disease, severe Stroke, history of May increase the risk of seizures. Bipolar disorder (type of depression), or risk of or Glaucoma, angle closure or Hypertension (high blood pressure) or Mania or hypomania (type of mental disease), history of or Psychosis (type of mental disease) or Schizophrenia (type of mental disease) Use with caution. May make these conditions worse. Kidney disease or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of bupropion This section provides information on the proper use of a number of products that contain bupropion. It may not be specific to Aplenzin. Please read with care. Take this medicine only as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. Swallow the tablet whole. Do not break, crush, or chew it. You may take this medicine with or without food. But if you have nausea, take the medicine with food. A part of the extended-release tablet may pass into your stool. This is normal and is nothing to worry about. Use of Zyban tablets: You may continue to smoke for about 1 week after you start the medicine. Set a target date to quit smoking during your second week of treatment. If you are still having trouble with quitting after using the medicine for at least 7 weeks, talk to your doctor. If you use a nicotine product (eg, patch) together with Zyban , do not smoke. Smoking may increase the chance for serious side effects. If you have trouble sleeping (insomnia), do not take this medicine too close to bedtime. If you use this medicine to prevent depression with seasonal affective disorder, take it during the autumn season before your symptoms start. Continue using the medicine through the winter season and until early spring. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (extended-release tablets): For depression: Adults Aplenzin : At first, 174 milligrams (mg) once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 522 mg per day. Forfivo XL : 450 mg once a day. Wellbutrin XL : At first, 150 mg once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children Use and dose must be determined by your doctor. For seasonal affective disorder: Adults Aplenzin : At first, 174 milligrams (mg) once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 522 mg per day. Wellbutrin XL : At first, 150 mg once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg once a day. Children Use and dose must be determined by your doctor. For oral dosage form (sustained-release tablets): For depression: Adults At first, 150 milligrams (mg) once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg two times per day, taken at least 8 hours apart. Children Use and dose must be determined by your doctor. To quit smoking: Adults At first, 150 milligrams (mg) once a day for the first 3 days. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day. Children Use and dose must be determined by your doctor. For oral dosage form (tablets): For depression: Adults At first, 100 milligrams (mg) two times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg three times per day, taken at least 6 hours apart. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you are taking the Wellbutrin XL extended-release tablet and you miss a dose, skip the missed dose and go back to your regular dosing schedule. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Aplenzin It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. Do not take bupropion with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan ], linezolid [Zyvox ], phenelzine [Nardil ], selegiline [Eldepryl ], tranylcypromine [Parnate ]). Do not start taking bupropion during the 2 weeks after you stop a MAO inhibitor. Wait for 2 weeks after stopping bupropion before you start taking a MAO inhibitor. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe convulsions. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS) . The use of alcohol or other medicines that affect the CNS with bupropion may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Bupropion may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. If you or your caregiver notice any of these side effects, tell your doctor right away. Your blood pressure might get too high while you are using this medicine. This may cause headaches, dizziness, or blurred vision. You might need to measure your blood pressure at home. If you think your blood pressure is too high, call your doctor right away. This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, swelling of the face, tongue, or throat, trouble breathing, or chest pain. Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or a skin rash, sores or ulcers on the skin, or fever or chills with this medicine. Drinking alcoholic beverages should be limited or avoided, if possible, with bupropion. This will help prevent seizures. This medicine may cause some people to have a false sense of wellbeing, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are drowsy, dizzy, or less alert . Do not stop taking this medicine without checking first with your doctor . Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. This is to decrease the chance of having certain side effects when you stop the medicine, such as agitation, anxiety, dizziness, a feeling of constant movement of self or surroundings, headaches, increased sweating, nausea, trembling or shaking, trouble with sleeping or walking, or unusual tiredness. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem. This medicine may cause a change in your appetite or weight. Your doctor may need to check your weight on a regular basis. Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Aplenzin Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Anxiety dry mouth hyperventilation irregular heartbeats irritability restlessness shaking trouble sleeping Less common Buzzing or ringing in the ears headache (severe) skin rash, hives, or itching Rare Confusion fainting false beliefs that cannot be changed by facts having extreme distrust of people seeing, hearing, or feeling things that are not there seizures trouble concentrating Incidence not known Actions that are out of control anger assaulting or attacking others being aggressive or impulsive chest pain or discomfort fast or pounding heartbeat force inability to sit still need to keep moving sweating talking, feeling, or acting with excitement Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Lightheadedness, dizziness, or fainting loss of consciousness slow or irregular heartbeat unusual tiredness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Constipation decrease in appetite dizziness increased sweating stomach pain trembling unusual weight loss Less common Blurred vision change in sense of taste drowsiness frequent need to urinate sore throat unusual feeling of well-being Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Aplenzin (bupropion) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 9 Reviews Add your own review/rating Drug class: miscellaneous antidepressants Consumer resources Aplenzin Other brands: Wellbutrin , Wellbutrin XL , Buproban , Wellbutrin SR , ... +4 more Professional resources Aplenzin (FDA) Bupropion Hydrochloride (AHFS Monograph) Related treatment guides Depression Major Depressive Disorder} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA WADA Class Anti-Doping Classification Manufacturer Valeant Pharmaceuticals International, Inc. Drug Class Miscellaneous antidepressants Related Drugs Major Depressive Disorder trazodone , sertraline , Zoloft , Lexapro , Cymbalta , Prozac , Wellbutrin , fluoxetine , venlafaxine , bupropion , duloxetine , escitalopram , More... Depression trazodone , sertraline , Xanax , citalopram , Zoloft , Lexapro , Cymbalta , Celexa , Prozac , Wellbutrin , alprazolam , fluoxetine , More... Aplenzin Rating 9 User Reviews 7.5 /10 9 User Reviews 7.5 Rate it! Aplenzin Images Aplenzin 348 mg (BR 348 ) View all images Related Questions & Answers I have been on zymbalta medicine for about 1 year. I have been off it for 3 days, and am taking? Anyone have success using Aplenzin and ADHD with kids? Heart Disease - ekg abnormalities withs seroquel, aplenzin, levaquin, and tricor? How do Aplenzin and generic bupropion differ in effectiveness? Which of the following medications have serotonin in them? Read more questions} } seems to be
standard Aplenzin (Oral) once in a while
EmoticonEmoticon