battle through doxylamine and pyridoxine (Oral route) dox-IL-a-meen SUX-i-nate, pir-i-DOX-een hye-droe-KLOR-ide Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Bonjesta Diclegis Available Dosage Forms: Tablet, Delayed Release Tablet, Extended Release Therapeutic Class: Antiemetic Pharmacologic Class: Doxylamine Chemical Class: Doxylamine Slideshow OTC Medication Use In Pregnancy: Wise or Worrisome? Uses For doxylamine and pyridoxine Doxylamine and pyridoxine combination is used to treat nausea and vomiting in pregnant women (also called morning sickness) whose symptoms have not been relieved by other therapies. doxylamine and pyridoxine is a combination of an antihistamine and vitamin B6. doxylamine and pyridoxine is available only with your doctor's prescription. Before Using doxylamine and pyridoxine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For doxylamine and pyridoxine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to doxylamine and pyridoxine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of doxylamine and pyridoxine combination in the pediatric population. Safety and efficacy have not been established. Geriatric No information is available on the relationship of age to the effects of doxylamine and pyridoxine combination in geriatric patients. Pregnancy Pregnancy Category Explanation All Trimesters A Adequate studies in pregnant women have not shown an increased risk of fetal abnormalities. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking doxylamine and pyridoxine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using doxylamine and pyridoxine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Furazolidone Iproniazid Isocarboxazid Linezolid Methylene Blue Moclobemide Nialamide Phenelzine Procarbazine Rasagiline Safinamide Selegiline Sodium Oxybate Toloxatone Tranylcypromine Using doxylamine and pyridoxine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acepromazine Alfentanil Alprazolam Altretamine Amisulpride Amobarbital Anileridine Aripiprazole Asenapine Baclofen Benperidol Bromazepam Bromopride Buprenorphine Bupropion Buspirone Butabarbital Carbinoxamine Carisoprodol Carphenazine Chloral Hydrate Chlordiazepoxide Chlorpromazine Chlorzoxazone Clobazam Clonazepam Clorazepate Clozapine Codeine Cyclobenzaprine Dexmedetomidine Diacetylmorphine Diazepam Dichloralphenazone Difenoxin Dihydrocodeine Diphenhydramine Diphenoxylate Donepezil Droperidol Enflurane Estazolam Eszopiclone Ethchlorvynol Ethopropazine Ethylmorphine Flibanserin Fluphenazine Flurazepam Fluspirilene Fospropofol Halazepam Haloperidol Halothane Hexobarbital Hydrocodone Hydromorphone Hydroxyzine Isoflurane Ketamine Ketazolam Ketobemidone Levorphanol Lorazepam Loxapine Meclizine Melperone Meperidine Mephobarbital Meprobamate Meptazinol Mesoridazine Metaxalone Methadone Methdilazine Methocarbamol Methohexital Methotrimeprazine Midazolam Molindone Moricizine Morphine Morphine Sulfate Liposome Nicomorphine Nitrazepam Nitrous Oxide Olanzapine Opium Opium Alkaloids Orphenadrine Oxazepam Oxycodone Oxymorphone Papaveretum Paregoric Pentobarbital Perampanel Perazine Periciazine Perphenazine Phenobarbital Pimozide Piperacetazine Pipotiazine Piritramide Prazepam Primidone Prochlorperazine Promazine Promethazine Propofol Quazepam Quetiapine Ramelteon Remifentanil Remoxipride Secobarbital Sertindole Sufentanil Sulpiride Tapentadol Temazepam Thiethylperazine Thiopental Thiopropazate Thioridazine Tilidine Tizanidine Tolonium Chloride Topiramate Tramadol Triazolam Trifluoperazine Trifluperidol Triflupromazine Trimeprazine Zaleplon Zolpidem Zopiclone Zotepine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using doxylamine and pyridoxine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use doxylamine and pyridoxine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Other Medical Problems The presence of other medical problems may affect the use of doxylamine and pyridoxine. Make sure you tell your doctor if you have any other medical problems, especially: Asthma or Bladder blockage or Bowel blockage or Glaucoma, narrow angle or Peptic ulcer Use with caution. May make these conditions worse. Proper Use of doxylamine and pyridoxine Take doxylamine and pyridoxine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. doxylamine and pyridoxine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions. Swallow the delayed-release tablet or extended-release tablet whole with a glass of water. Do not crush, break, or chew it. It is best to take doxylamine and pyridoxine on an empty stomach. Dosing The dose of doxylamine and pyridoxine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of doxylamine and pyridoxine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For treatment of nausea and vomiting during pregnancy: For oral dosage form (delayed-release tablets): Adults Two tablets taken at bedtime (Day 1). If symptoms are controlled the following day, continue taking two tablets at bedtime. If symptoms persists in the afternoon of Day 2, take two tablets at bedtime and start taking three tablets on Day 3 (one tablet in the morning and two tablets at bedtime). If symptoms are controlled on Day 4, continue taking three tablets daily. Otherwise, take one tablet in the morning, one tablet in the mid-afternoon, and two tablets at bedtime (total of 4 tablets). Children Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults One tablet taken at bedtime (Day 1). If symptoms are controlled the following day, continue taking 1 tablet at bedtime. If symptoms persists on Day 2, take one tablet in the morning and one tablet at bedtime. However, the dose is usually not more than 2 tablets per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of doxylamine and pyridoxine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using doxylamine and pyridoxine It is important that your doctor check your progress while taking doxylamine and pyridoxine . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms do not improve or if they become worse, check with your doctor. You should not use doxylamine and pyridoxine together with a MAO inhibitor (MAOI) such as Eldepryl , Marplan , Nardil , or Parnate . Using these medicines together may cause serious unwanted effects . doxylamine and pyridoxine may make you drowsy or sleepy. Make sure you know how to react to doxylamine and pyridoxine before you drive, use machines, or do anything else that could be dangerous if you are not alert . doxylamine and pyridoxine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking doxylamine and pyridoxine . doxylamine and pyridoxine may cause dry mouth. A dry mouth may also damage your teeth and gums. To help prevent this condition, carefully brush your teeth at least two times a day and have regular visits with your dentist. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. doxylamine and pyridoxine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Incidence not known Chest discomfort decrease in the frequency of urination decrease in urine volume difficult or labored breathing difficult or painful urination fast, irregular, pounding, or racing heartbeat or pulse swelling of the eyelids, face, lips, hands, or feet Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Unusual drowsiness Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about doxylamine/pyridoxine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 83 Reviews Add your own review/rating Drug class: miscellaneous antiemetics Consumer resources Doxylamine and pyridoxine Other brands: Diclegis , Bonjesta Professional resources Related treatment guides Nausea/Vomiting Nausea/Vomiting of Pregnancy} Drug Status Rx Availability Prescription only A Pregnancy Category Studies show no risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Miscellaneous antiemetics Related Drugs Nausea / Vomiting of Pregnancy Diclegis , calcium / folic acid / ginger / pyridoxine , doxylamine / pyridoxine , Zingiber , B-Nexa , Bonjesta , More... Nausea / Vomiting promethazine , lorazepam , meclizine , ondansetron , Zofran , hydroxyzine , Ativan , diphenhydramine , Benadryl , metoclopramide , prochlorperazine , Reglan , More... Doxylamine / pyridoxine Rating 83 User Reviews 6.9 /10 83 User Reviews 6.9 Rate it! Help and Support Looking for answers? Ask a question or go join the doxylamine / pyridoxine support group to connect with others who have similar interests.} } land up
is provided with doxylamine and pyridoxine (Oral route) overlooked
EmoticonEmoticon