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life like Clinac BPO 7 Generic Name: benzoyl peroxide Dosage Form: gel Side Effects Dosage Professional Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here. Clinac BPO 7 (Benzoyl Peroxide Gel USP, 7%) Acne Control Gel Clinac BPO 7 Description Clinac BPO 7 (benzoyl peroxide) is a topical preparation containing 7% benzoyl peroxide as the active ingredient in a gel vehicle containing purified water, propylene glycol, Acrysorb (brand of acrylates copolymer), PEG-400, carbomer 940, disodium EDTA, and sodium hydroxide. The chemical structure for the active ingredient is: benzoyl peroxide C 14 H 10 O 4 (anhydrous) 242.23 Slideshow Newborn Baby Health: 8 Woes From Cradle Cap And Colic To Whooping Cough Clinac BPO 7 - Clinical Pharmacology The exact method of action of benzoyl peroxide in acne vulgaris is not known. Benzoyl Peroxide is an antibacterial agent with demonstrated activity against Propionibacterium acnes . This action combines with the mild keratolytic effect of benzoyl peroxide is believed to be responsible for its usefulness in acne. Little is known about the percutaneous penetration, metabolism and excretion of benzoyl peroxide. Benzoyl peroxide is absorbed by the skin where it is metabolized to benzoic acid and excreted as benzoate in the urine. There is no evidence of systemic toxicity caused by benzoyl peroxide in humans. Indications and Usage for Clinac BPO 7 Clinac BPO 7 is indicated for the topical treatment of mild to moderate acne vulgaris. Contraindications Clinac BPO 7 should not be used in patients who have shown hypersensitivity to benzoyl peroxide or any of the other ingredients in this product. Warnings FOR EXTERNAL USE ONLY. KEEP OUT OF REACH OF CHILDREN. Avoid contact with eyes, eyelids, lips and mucous membranes. If inadvertent contact occurs, rinse area thoroughly with water. Contact with colored material, including fabric and hair, may result in discoloration. When using Clinac BPO 7, avoid unnecessary sun exposure and use a sunscreen. In case of accidental ingestion, seek professional assistance or contact a poison control center immediately. Precautions Information for Patients Avoid contact with eyes, eyelids, lips and mucous membranes. May discolor hair and fabrics. Avoid unnecessary sun exposure and use a sunscreen. Use of oil-free make-up recommended. If severe irritation develops, discontinue use and consult your physician. Carcinogenesis, Mutagenesis and Impairment of Fertility Studies employing a strain of mice that are highly susceptible to developing cancer suggest that benzoyl peroxide act as a tumor promoter. The clinical significance of these finding to humans is not known. Benzoyl peroxide has not been found to be mutagenic (Ames test) and there are no published data indicating that it impairs fertility. Pregnancy: Category C Animal reproductive studies have not been conducted with benzoyl peroxide. It is also not known whether benzoyl peroxide can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Benzoyl peroxide should be used by a pregnant woman only if clearly needed. There are no available data on the effect of benzoyl peroxide on the later growth, development and functional maturation of the unborn child. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when benzoyl peroxide is administered to a nursing woman. Pediatric Use Safety and effectiveness in children below the age of 12 have not been established. Adverse Reactions Allergic contact dermatitis and dryness have been reported with topical benzoyl peroxide therapy. If excessive scaling, erythema or edema occurs, the use of Clinac BPO 7 should be discontinued and appropriate therapy instituted. To hasten resolution of adverse effects, cool compresses may be used. After reaction clears, a reduced dosage schedule may often be resumed if the reaction is judged not to be due to allergenicity. Clinac BPO 7 Dosage and Administration Wash and dry hands, face and affected areas with a gentle cleanser before application. Apply a thin layer of Clinac BPO 7 to the affected area once or twice daily, or as directed by your physician. Replace cap tightly after use. How is Clinac BPO 7 Supplied Clinac BPO 7 Gel 45 gram tube NDC 0496-0857-45 Store at 25 C (77 F); excusions permitted to 15-30 C (59-86 F) [see USP Controlled Room Temperature.]. Rx Only. Ferndale Laboratories, Inc. Ferndale, MI 48220 U.S.A Toll free (888) 548-0900 www.ferndalelabs.com Protected under U.S. Patent. Clinac and Acrysorb are registered trademarks of Dow Pharmaceutical Sciences Corp. Package Label Clinac BPO 7 benzoyl peroxide gel Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0496-0857 Route of Administration TOPICAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength BENZOYL PEROXIDE (BENZOYL PEROXIDE) BENZOYL PEROXIDE 70 mg in 1 g Inactive Ingredients Ingredient Name Strength WATER PROPYLENE GLYCOL POLYETHYLENE GLYCOLS CARBOMER HOMOPOLYMER TYPE C EDETATE DISODIUM SODIUM HYDROXIDE Packaging # Item Code Package Description 1 NDC:0496-0857-45 45 g in 1 TUBE 2 NDC:0496-0857-90 90 g in 1 TUBE 3 NDC:0496-0857-97 1 g in 1 POUCH 4 NDC:0496-0857-98 4 g in 1 TUBE Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 09/12/2000 11/30/2012 Labeler - Ferndale Laboratories, Inc. (005320536) Establishment Name Address ID/FEI Operations Ferndale Laboratories, Inc. 005320536 manufacture Revised: 03/2012 Ferndale Laboratories, Inc. Next Interactions Print this page Add to My Med List More about Clinac BPO (benzoyl peroxide topical) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: topical acne agents Consumer resources Professional resources Benzoyl Peroxide Wash (FDA) Other brands: BenzePro , PanOxyl , Peroderm 7 Wash , Triaz , ... +15 more Related treatment guides Acne Perioral Dermatitis FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Topical acne agents Related Drugs topical acne agents clindamycin topical , erythromycin topical , tretinoin topical , tetracycline topical , dapsone topical , Finacea Acne doxycycline , clindamycin topical , erythromycin topical , minocycline , tretinoin topical , tetracycline , dapsone topical , Accutane , Vibramycin , Retin-A , isotretinoin , More... Perioral Dermatitis metronidazole topical , clindamycin topical , MetroGel , benzoyl peroxide topical , Cleocin T , MetroCream , Noritate , Clindagel , Acne Treatment , MetroLotion , Oxy-10 , Evoclin , More... Clinac BPO Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! and cannot


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