the plain carmustine (Implantation route) kar-MUS-teen Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Gliadel Available Dosage Forms: Implant Therapeutic Class: Antineoplastic Agent Pharmacologic Class: Alkylating Agent Chemical Class: Nitrosourea Slideshow Multiple Myeloma: Has Crowd Control Ever Been As Important? Uses For carmustine Carmustine implant is used together with surgery and radiation therapy to treat malignant glioma and glioblastoma multiforme. These are types of brain cancer. Carmustine belongs to the group of cancer medicines known as alkylating agents. It interferes with the growth of cancer cells, which are eventually destroyed. carmustine is to be given only by or under the direct supervision of your doctor. Before Using carmustine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For carmustine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to carmustine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of carmustine implant in the pediatric population. Safety and efficacy have not been established. Geriatric Although appropriate studies on the relationship of age to the effects of carmustine implant have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving carmustine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using carmustine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Measles Virus Vaccine, Live Mumps Virus Vaccine, Live Rotavirus Vaccine, Live Rubella Virus Vaccine, Live Varicella Virus Vaccine Using carmustine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Adenovirus Vaccine Bacillus of Calmette and Guerin Vaccine, Live Cholera Vaccine, Live Cimetidine Influenza Virus Vaccine, Live Phenobarbital Poliovirus Vaccine, Live Smallpox Vaccine Typhoid Vaccine Yellow Fever Vaccine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of carmustine. Make sure you tell your doctor if you have any other medical problems, especially: Intracranial hypertension (increased pressure in the head) or Seizures Use with caution. May make these conditions worse. Proper Use of carmustine Medicines used to treat cancer are very strong and can have many side effects. Before receiving carmustine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment. A doctor will place carmustine in your brain during a surgical procedure. It is in the form of a small wafer. The wafer will dissolve and slowly release the medicine in the tumor. Precautions While Using carmustine It is important that your doctor check your progress closely while you are receiving carmustine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects. Using carmustine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant after receiving the medicine. If you think you have become pregnant while using carmustine, tell your doctor right away. carmustine may cause seizures after the surgical procedure. Call your doctor if you have symptoms of seizures after receiving carmustine. carmustine may cause increased pressure in the head (intracranial hypertension). Tell your doctor right away if you have a severe headache, nausea, vomiting, blurred vision, or any change in vision after receiving the implant. carmustine may cause a brain infection called meningitis. Tell your doctor right away if you have a severe headache, confusion, drowsiness, nausea, a general feeling of illness, or a stiff neck. Some men using carmustine have become infertile (unable to have children). If you plan to have children, talk to your doctor before receiving carmustine. carmustine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Blurred vision change in ability to see colors, especially blue or yellow confusion fever headache nausea and vomiting problems with movement, walking, or speech seizures trouble healing Less common Drowsiness general feeling of illness severe headache stiff neck or back Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain back pain bladder pain bloody or cloudy urine difficult, burning, or painful urination difficulty having a bowel movement (stool) discouragement feeling sad or empty frequent urge to urinate irritability lack of appetite lack or loss of strength loss of interest or pleasure lower back or side pain tiredness trouble concentrating trouble sleeping Less common Chest pain Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. 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Next Side Effects Print this page Add to My Med List More about carmustine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: alkylating agents Consumer resources Carmustine Carmustine Injection Carmustine Intracranial Implant Carmustine Intravenous (Advanced Reading) Other brands: Gliadel , BiCNU Professional resources Carmustine (AHFS Monograph) Carmustine (Wolters Kluwer) Related treatment guides Brain Tumor Glioblastoma Multiforme Hodgkin's Lymphoma Malignant Glioma Multiple Myeloma Non-Hodgkin's Lymphoma} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Alkylating agents Related Drugs Hodgkin's Lymphoma Opdivo , Keytruda , cyclophosphamide , nivolumab , Cytoxan , etoposide , More... Non-Hodgkin's Lymphoma methotrexate , Rituxan , rituximab , cyclophosphamide , Imbruvica , Cytoxan , More... Glioblastoma Multiforme Avastin , bevacizumab , Temodar , temozolomide , carmustine , Gliadel , More... Brain Tumor cisplatin , lomustine , carmustine , Gliadel , Platinol , Gleostine , More... 2 more conditions... Carmustine Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the carmustine support group to connect with others who have similar interests.} } massive
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