top notch uscular required to achieve neuromuscular blocking effects; possibly due to blockade. phosphodiesterase inhibition. Pentoxifylline Decreases theophylline clearance. 30% increase Phenobarbital Similar to aminoglutethimide 25% decrease after two weeks of (PB) concurrent Phenobarbital. Phenytoin Phenytoin increases theophylline Serum theophylline and phenytoin clearance by increasing microsomal concentrations decrease about 40%. enzyme activity. Theophylline decreases phenytoin absorption Propafenone Decreases theophylline clearance 40% increase. Beta-2 blocking effect and pharmacologic interaction. may decrease efficacy of Theophylline. Propranolol Similar to cimetidine and 100% increase. Beta-2 blocking effect pharmacologic interaction. effect may decrease efficacy of theophylline. Rifampin Increases theophylline clearance by 20 - 40% decrease increasing cytochrome P450 1A2 and 3A3 activity. Sulfinprazone Increases theophylline clearance by 20% decrease increasing demethylation and hydroxylation. Decreases renal clearance of theophylline. Tacrine Similar to cimetidine suits
Photo :uscular required to achieve neuromuscular blocking effects; possibly due to blockade. phosphodiesterase inhibition. Pentoxifylline Decreases theophylline clearance. 30% increase Phenobarbital Similar to aminoglutethimide 25% decrease after two weeks of (PB) concurrent Phenobarbital. Phenytoin Phenytoin increases theophylline Serum theophylline and phenytoin clearance by increasing microsomal concentrations decrease about 40%. enzyme activity. Theophylline decreases phenytoin absorption Propafenone Decreases theophylline clearance 40% increase. Beta-2 blocking effect and pharmacologic interaction. may decrease efficacy of Theophylline. Propranolol Similar to cimetidine and 100% increase. Beta-2 blocking effect pharmacologic interaction. effect may decrease efficacy of theophylline. Rifampin Increases theophylline clearance by 20 - 40% decrease increasing cytochrome P450 1A2 and 3A3 activity. Sulfinprazone Increases theophylline clearance by 20% decrease increasing demethylation and hydroxylation. Decreases renal clearance of theophylline. Tacrine Similar to cimetidine uninjured also increases 90% increase renal clearance of theophylline. Thiabendazole Decreases theophylline clearance. 190% increase Ticlopidine Decreases theophylline clearance. 60% increase Troleandomycin Similar to erythromycin. 33 - 100% increase depending on troleandomycin dose. Verapamil Similar to disulfiram. 20% increase *Refer to PRECAUTIONS you truly
snoozing uscular required to achieve neuromuscular blocking effects; possibly due to blockade. phosphodiesterase inhibition. Pentoxifylline Decreases theophylline clearance. 30% increase Phenobarbital Similar to aminoglutethimide 25% decrease after two weeks of (PB) concurrent Phenobarbital. Phenytoin Phenytoin increases theophylline Serum theophylline and phenytoin clearance by increasing microsomal concentrations decrease about 40%. enzyme activity. Theophylline decreases phenytoin absorption Propafenone Decreases theophylline clearance 40% increase. Beta-2 blocking effect and pharmacologic interaction. may decrease efficacy of Theophylline. Propranolol Similar to cimetidine and 100% increase. Beta-2 blocking effect pharmacologic interaction. effect may decrease efficacy of theophylline. Rifampin Increases theophylline clearance by 20 - 40% decrease increasing cytochrome P450 1A2 and 3A3 activity. Sulfinprazone Increases theophylline clearance by 20% decrease increasing demethylation and hydroxylation. Decreases renal clearance of theophylline. Tacrine Similar to cimetidine shopper
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