healing procedures Tagrisso Generic Name: Osimertinib (oh si mer ti nib) Brand Name: Tagrisso Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Uses of Tagrisso: It is used to treat lung cancer. What do I need to tell my doctor BEFORE I take Tagrisso? If you have an allergy to Tagrisso (osimertinib) or any part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are breast-feeding. Do not breast-feed while you take Tagrisso and for 2 weeks after your last dose. This medicine may interact with other drugs or health problems. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Slideshow Looking Ahead: New Drug Approvals for 2017 What are some things I need to know or do while I take Tagrisso? Tell all of your health care providers that you take Tagrisso. This includes your doctors, nurses, pharmacists, and dentists. You will need to have heart function tests while taking this medicine. Talk with the doctor. You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. This medicine may cause a type of abnormal heartbeat (prolonged QT interval). If this happens, the chance of other unsafe and sometimes deadly abnormal heartbeats may be raised. Talk with the doctor. If you are 65 or older, use Tagrisso with care. You could have more side effects. This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. In both men and women, this may go back to normal but sometimes it may not. Talk with your doctor. If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for at least 4 months after stopping this medicine. Use birth control that you can trust. If you are a man and your sex partner gets pregnant while you take Tagrisso or within 4 months after your last dose, call your doctor right away. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Use birth control that you can trust to prevent pregnancy while taking this medicine and for 6 weeks after your last dose. If you get pregnant while taking Tagrisso or within 6 weeks after your last dose, call your doctor right away. How is this medicine (Tagrisso) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. To gain the most benefit, do not miss doses. Keep taking Tagrisso as you have been told by your doctor or other health care provider, even if you feel well. If you have trouble swallowing, the tablet may be mixed in 2 ounces (60 mL) of water. Do not use carbonated water or other liquids. Stir well until the tablet is in small pieces. Do not crush or heat. Swallow right away. After drinking, rinse the container with 4 to 8 ounces (120 to 240 mL) of water and drink right away. Those who have feeding tubes may use this medicine. Use as you have been told. Flush the feeding tube after Tagrisso (osimertinib) is given. What do I do if I miss a dose? Skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal. Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop. Dizziness or passing out. A fast heartbeat. A heartbeat that does not feel normal. Feeling very tired or weak. Change in eyesight, eye pain, or very bad eye irritation. If bright lights bother your eyes. Watery eyes. Very bad and sometimes deadly lung or breathing problems have happened with this medicine. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse. Heart failure has rarely happened in people taking Tagrisso. Sometimes, this has been deadly. Call your doctor right away if you have shortness of breath, a big weight gain, or swelling in the arms or legs. What are some other side effects of Tagrisso? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Loose stools (diarrhea). Dry skin. Change in nails. Upset stomach or throwing up. Not hungry. Hard stools (constipation). Mouth irritation or mouth sores. Feeling tired or weak. Back pain. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Tagrisso? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take Tagrisso or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Tagrisso. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Tagrisso (osimertinib) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: EGFR inhibitors Consumer resources Tagrisso Tagrisso (Advanced Reading) Professional resources Tagrisso (AHFS Monograph) Tagrisso (FDA) Related treatment guides Non-Small Cell Lung Cancer} Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug 2 years Approval History FDA approved 2015 Tagrisso Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Manufacturer AstraZeneca Drug Class EGFR inhibitors Related Drugs Non-Small Cell Lung Cancer Avastin , methotrexate , Taxol , Opdivo , cisplatin , Taxotere , Tarceva , Keytruda , paclitaxel , nivolumab , gemcitabine , Gemzar , Abraxane , docetaxel , Alimta , bevacizumab , pembrolizumab , pemetrexed , erlotinib , Trexall , Tecentriq , crizotinib , Cyramza , atezolizumab , More... Tagrisso Images Tagrisso 40 mg (AZ 40 ) View larger images Related: Non-Small Cell Lung Cancer} } one of these
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