medical health insurance Dryvax (Injection) Generic Name: smallpox vaccine (Injection route) SMAWL-pox VAX-een Injection route(Powder for Solution) Myocarditis, pericarditis, encephalitis, encephalomyelitis, encephalopathy, progressive vaccinia, generalized vaccinia, severe vaccinial skin infections, erythema multiforme major (including Stevens-Johnson syndrome), eczema vaccinatum resulting in permanent sequelae or death, ocular complications and blindness and fetal death, have occurred following primary vaccination or revaccination. Certain individuals are at an increased risk which may lead to severe disability, permanent neurological sequelae and/or death . Overview Side Effects Dosage Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. ACAM2000 Dryvax Available Dosage Forms: Powder for Suspension Powder for Solution Therapeutic Class: Vaccine Slideshow Vaccine Safety: Your Questions Answered Uses For Dryvax Smallpox vaccine is an active immunizing agent used to prevent smallpox infection. It works by causing your immune system to produce its own protection (antibodies) against the virus . This vaccine should only be administered by or under the supervision of your doctor or another health care professional . This medicine is available only with a doctor's prescription . Before Using Dryvax In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of smallpox vaccine in children less than 16 years of age. Safety and efficacy have not been established . Geriatric No information is available on the relationship of age to the effects of smallpox vaccine in geriatric patients . Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Receiving this vaccine with any of the following medicines is not recommended. Your doctor may decide not to use this vaccine or change some of the other medicines you take. Deflazacort Thiotepa Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Adalimumab Alemtuzumab Antithymocyte Globulin Rabbit Azathioprine Bendamustine Bortezomib Bosutinib Brodalumab Cabazitaxel Capecitabine Carboplatin Carfilzomib Carmustine Certolizumab Pegol Chlorambucil Cisplatin Cladribine Clofarabine Cyclophosphamide Cyclosporine Cytarabine Cytarabine Liposome Dacarbazine Dasatinib Daunorubicin Daunorubicin Citrate Liposome Docetaxel Doxorubicin Dupilumab Epirubicin Etanercept Etoposide Everolimus Fingolimod Fludarabine Fluorouracil Gemcitabine Gemtuzumab Ozogamicin Golimumab Guselkumab Hydroxyurea Idarubicin Ifosfamide Imatinib Immune Globulin Infliximab Interferon Alfa Irinotecan Irinotecan Liposome Leflunomide Lomustine Mechlorethamine Melphalan Mercaptopurine Methotrexate Mitomycin Mitoxantrone Mycophenolic Acid Nelarabine Nilotinib Ofatumumab Oxaliplatin Paclitaxel Paclitaxel Protein-Bound Pemetrexed Pentostatin Ponatinib Procarbazine Rilonacept Rituximab Sarilumab Secukinumab Sirolimus Temozolomide Teniposide Teriflunomide Tocilizumab Topotecan Tositumomab Trabectedin Ustekinumab Vinblastine Vinorelbine Receiving this vaccine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abatacept Cytomegalovirus Immune Globulin, Human Hepatitis B Immune Globulin Rabies Immune Globulin Respiratory Syncytial Virus Immune Globulin, Human Tetanus Immune Globulin Vaccinia Immune Globulin, Human Varicella-Zoster Immune Globulin Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially: Bone marrow transplant or Cancer or HIV or AIDS or Immune deficiency conditions or Leukemia (cancer of the blood) or Lymphoma (cancer of the lymph nodes) Organ transplant Should not use in patients with these conditions . Burns, severe or Chest pain or Chickenpox or Congestive heart failure or Dermatitis or Diabetes or Eczema or Eye disease or Heart attack, history of or Heart disease (or family history of) or High blood pressure or High cholesterol in the blood or Impetigo or Psoriasis or Shingles or Stroke May increase the chance and severity of side effects . Proper Use of smallpox vaccine This section provides information on the proper use of a number of products that contain smallpox vaccine. It may not be specific to Dryvax. Please read with care. A nurse or other trained health professional will give you this vaccine. This vaccine is given by using a needle to poke or jab the skin on your upper arm . You may need a booster dose of this vaccine every three years to maintain protection against smallpox. Ask your doctor if you will need another dose of this vaccine . This vaccine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions . Precautions While Using Dryvax It is very important that your doctor check your progress at regular visits to make sure this vaccine is working properly and to check for unwanted effects . This vaccine may cause serious heart problems in some patients. Check with your doctor right away if you are having chest pain or discomfort; dizziness; fast or irregular heartbeat; fever and chills; shortness of breath; sweating, weakness; or trouble breathing . Tell your doctor if you smoke cigarettes or other tobacco products. The risk of heart problems is increased in people who smoke . You should not receive this vaccine if you are using medicines that weaken your immune system, such as steroids, radiation, or cancer medicines . You should not become pregnant for at least 3 months after receiving this vaccine without first checking with your doctor. There is a chance that this vaccine may cause problems during pregnancy. If you think you have become pregnant, tell your doctor right away . This vaccine contains neomycin and polymyxin B. Make sure your doctor knows if you have had an allergic reaction to these medicines . This vaccine contains a live virus. The virus can cause an infection in other parts of your body or in other people if you touch the vaccination site and then touch your body or other people. Always cover the vaccination site with a bandage. Wash your hands thoroughly after changing the bandage or after touching the vaccination site. Your doctor will tell you how to care for the vaccination site. Make sure you understand the directions and follow them carefully. Avoid contact with people who are sick or have infections until the scab falls off (usually 2 to 4 weeks after vaccination). Talk to your doctor about this if you have concerns . You must wait at least 30 days before you can donate blood, use a hot tub or swim, handle a baby, or breastfeed . Before you have any medical tests for syphilis or a tuberculin (TB) skin test, tell the medical doctor in charge that you have received this vaccine. The results of these tests may be affected by this vaccine . Dryvax Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Feeling unusually cold shivering swollen, painful, or tender lymph glands in the neck, armpit, or groin Less common Agitation anxiety back pain blindness blistering, peeling, or loosening of skin blue or pale skin blurred vision changes in vision chest discomfort chest pain, possibly moving to the left arm, neck, or shoulder confusion convulsions (seizures) cough diarrhea difficult or labored breathing dizziness drowsiness fast heartbeat fever and chills hallucinations headache irritability itching joint or muscle pain loss of consciousness mood or mental changes red skin lesions, often with a purple center red, irritated eyes shortness of breath skin rash that is encrusted, scaly, and oozing sore throat sores, ulcers, or white spots in the mouth or on the lips stiff neck tightness in the chest trouble breathing unusual tiredness or weakness vomiting wheezing Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Decreased ability to exercise difficulty having a bowel movement (stool) difficulty with moving flushing or redness of the skin general feeling of discomfort or illness itching, pain, redness, or swelling at the vaccine site muscle aching or cramping muscle stiffness nausea rash swollen joints unusually warm skin Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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