for that reason Tecentriq Side Effects Generic Name: atezolizumab Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Note: This document contains side effect information about atezolizumab. Some of the dosage forms listed on this page may not apply to the brand name Tecentriq. For the Consumer Applies to atezolizumab: intravenous solution Along with its needed effects, atezolizumab (the active ingredient contained in Tecentriq) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur while taking atezolizumab: More common Bladder pain bloating or swelling of the face, arms, hands, lower legs, or feet bloody or cloudy urine constipation cough or hoarseness difficult, burning, or painful urination fever or chills frequent urge to urinate general tiredness and weakness loss of appetite lower back or side pain nausea or vomiting pain painful or difficult urination rapid weight gain stomach cramps tenderness tingling of the hands or feet unusual weight gain or loss watery or bloody diarrhea Less common Chest pain dark urine depressed mood dizziness dry skin and hair facial swelling feeling cold general feeling of discomfort or illness hair loss headache hoarseness or husky voice light-colored stools muscle cramps and stiffness nervousness sensitivity to heat skin rash slowed heartbeat sweating thickening of bronchial secretions trouble sleeping troubled breathing unusual tiredness or weakness upper right abdominal or stomach pain weakness yellow eyes and skin Less common or rare Burning, tingling, numbness or pain in the hands, arms, feet, or legs confusion difficulty with chewing, swallowing, or talking double vision drooping eyelids drowsiness headache inability to move the arms and legs irritability muscle weakness seizures sensation of pins and needles severe headache severe tiredness stabbing pain stiff neck or back sudden numbness and weakness in the arms and legs Rare Bloating darkening of the skin diarrhea fainting fast heartbeat indigestion pains in the stomach, side, or abdomen, possibly radiating to the back Incidence not known Blurred vision dry mouth flushed, dry skin fruit-like breath odor increased hunger increased thirst increased urination sweating Some side effects of atezolizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Back or neck pain itching skin pain in the joints For Healthcare Professionals Applies to atezolizumab: intravenous solution Cardiovascular Common (1% to 10%): Venous thromboembolism [ Ref ] Dermatologic Very common (10% or more): Rash (15%), pruritus (13%) [ Ref ] Endocrine Frequency not reported: Immune-related thyroid disorders (e.g., hyperthyroidism, hypothyroidism) [ Ref ] Gastrointestinal Very common (10% or more): Nausea (25%), constipation (21%), diarrhea (18%), abdominal pain (17%), vomiting (17%) Common (1% to 10%): Dehydration, intestinal obstruction [ Ref ] General The most common adverse reactions (greater than 20%) were fatigue, decreased appetite, nausea, urinary tract infection, pyrexia, and constipation. The most common Grade 3 to 4 adverse reactions (greater than 2%) were urinary tract infection, anemia, fatigue, dehydration, intestinal obstruction, urinary obstruction, hematuria, dyspnea, acute kidney injury, abdominal pain, venous thromboembolism, sepsis, and pneumonia. [ Ref ] Genitourinary Very common (10% or more): Urinary tract infection (22%) Common (1% to 10%): Urinary obstruction [ Ref ] Hematologic Common (1% to 10%): Anemia, lymphopenia, increased alkaline phosphatase, increased alkaline phosphatase [ Ref ] Hepatic Common (1% to 10%): Acute kidney injury, liver enzyme increase, increased ALT, increased AST Immunologic Very common (10% or more): Immune related colitis (19.7%) Common (1% to 10%): Immune related pneumonitis, immune related hepatitis, sepsis Frequency not reported: Immune related endocrinopathies [ Ref ] Local Frequency not reported: Infusion related reactions [ Ref ] Metabolic Very common (10% or more): Decreased appetite (26%) Common (1% to 10%): Hyponatremia, hyperglycemia, hypoalbuminemia [ Ref ] Musculoskeletal Very common (10% or more): Back/neck pain (15%), arthralgia (14%) [ Ref ] Nervous system Frequency not reported: Meningoencephalitis, myasthenic syndrome/myasthenia gravis, Guillain-Barre [ Ref ] Ocular Frequency not reported: Ocular inflammatory toxicity [ Ref ] Other Very common (10% or more): Fatigue (52%), pyrexia (21%), peripheral edema (18%) Common (1% to 10%): Increased creatinine [ Ref ] Psychiatric Common (1% to 10%): Confusional state [ Ref ] Renal Common (1% to 10%): Hematuria [ Ref ] Respiratory Very common (10% or more): Dyspnea (16%), cough (14%) Common (1% to 10%): Dyspnea, pneumonia [ Ref ] References 1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 2. "Product Information. Tecentriq (atezolizumab)." Genentech, South San Francisco, CA. Some side effects of Tecentriq may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA . Next Dosage Print this page More about Tecentriq (atezolizumab) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 1 Review Add your own review/rating Drug class: Anti-PD-1 monoclonal antibodies Consumer resources Tecentriq Tecentriq (Advanced Reading) Professional resources Tecentriq (AHFS Monograph) Tecentriq (FDA) Related treatment guides Bladder Cancer Non-Small Cell Lung Cancer Urothelial Carcinoma Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer Genentech, Inc. Drug Class Anti-PD-1 monoclonal antibodies Related Drugs Non-Small Cell Lung Cancer Avastin , methotrexate , Taxol , Opdivo , cisplatin , Taxotere , Tarceva , Keytruda , More... Bladder Cancer cisplatin , Adriamycin , doxorubicin , mitomycin , atezolizumab , thiotepa , Platinol , Mutamycin , More... Urothelial Carcinoma Opdivo , Keytruda , nivolumab , pembrolizumab , atezolizumab , Imfinzi , avelumab , durvalumab , More... Tecentriq Rating 1 User Review 1 User Review Not Rated - Be the first! even supposing
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