provided that abacavir and lamivudine (Oral route) a-BAK-a-vir SUL-fate, la-MIV-ue-deen Oral route(Tablet) Serious and fatal hypersensitivity reactions have been reported with abacavir; discontinue if a hypersensitivity reaction is suspected and never restart an abacavir-containing product after a hypersensitivity reaction as potentially fatal reactions may recur within hours. Patients with HLA-B*5701 allele are at a higher risk for abacavir-related hypersensitivity; screening for allele is recommended prior to initiating or reinitiation of therapy unless previous allele assessment is documented. Use is contraindicated in those with the HLA-B*5701 allele or with a previous hypersensitivity reaction to abacavir. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with nucleoside analogues and other antiretrovirals. Discontinue if these conditions are suspected. Severe acute exacerbations of hepatitis B have been reported in patients co-infected with HBV and HIV who have discontinued lamivudine; monitor hepatic function closely for several months upon discontinuation of therapy; initiation of anti-HBV therapy may be needed . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Epzicom Available Dosage Forms: Tablet Therapeutic Class: Antiretroviral Agent Pharmacologic Class: Abacavir Slideshow 10 Serious Infections That Will Make You Shudder Uses For abacavir and lamivudine Abacavir and lamivudine combination is used together with other medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Abacavir and lamivudine combination will not cure or prevent HIV infection or the symptoms of AIDS. abacavir and lamivudine helps keep HIV from reproducing, and appears to slow down the destruction of the immune system. This may help delay the development of serious health problems usually related to AIDS or HIV infection. Abacavir and lamivudine combination will not keep you from spreading HIV to other people. People who receive abacavir and lamivudine may continue to have other problems usually related to AIDS or HIV infection. abacavir and lamivudine is available only with your doctor's prescription. Before Using abacavir and lamivudine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For abacavir and lamivudine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to abacavir and lamivudine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Epzicom in children. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Epzicom in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving Epzicom . Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking abacavir and lamivudine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using abacavir and lamivudine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Dasabuvir Orlistat Ribavirin Using abacavir and lamivudine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Methadone Tipranavir Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of abacavir and lamivudine. Make sure you tell your doctor if you have any other medical problems, especially: Diabetes or Heart disease or Hepatitis B, history of or Hepatitis C, history of or Hyperlipidemia (high cholesterol or fats in the blood) or Hypertension (high blood pressure) Use with caution. May make these conditions worse. Genetic condition (eg, gene variation called HLA-B*5701) Kidney disease, severe or Liver disease, moderate or severe Should not be used in patients with these conditions. Proper Use of abacavir and lamivudine Take abacavir and lamivudine exactly as directed by your doctor . Do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not start or stop taking abacavir and lamivudine without checking first with your doctor. abacavir and lamivudine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. abacavir and lamivudine can be taken with or without food. When your supply of abacavir and lamivudine runs low, get more from your pharmacy or from your doctor. The amount of virus in your blood may increase if the medicine is stopped, even for a short time. The virus may develop resistance to abacavir and lamivudine and be harder to treat. abacavir and lamivudine will be given together with other medicines for HIV infection. Take all of the medicines your doctor gives you at the right time of day. These medicines work best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses . If you need help in planning the best times to take your medicines, check with your doctor. Abacavir and lamivudine combination contains a fixed amount of each medicine in the tablet. Dosing The dose of abacavir and lamivudine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of abacavir and lamivudine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For HIV infection: Adults One tablet once a day. Each tablet contains 600 milligrams (mg) of abacavir and 300 mg of lamivudine. Children weighing at least 25 kilograms (kg) One tablet once a day. Children weighing less than 25 kg Use and dose must be determined by your doctor. Missed Dose If you miss a dose of abacavir and lamivudine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using abacavir and lamivudine It is very important that your doctor check your or your child's progress at regular visits to make sure abacavir and lamivudine is working properly. Blood tests may be needed to check for unwanted effects. abacavir and lamivudine may cause severe allergic reactions (including multi-organ failure) in some patients. This reaction usually occurs within 6 weeks after the medicine is started, but may occur at any time. If untreated, it can lead to severe low blood pressure and even death. Check with your doctor right away if you have sudden fever, skin rash, diarrhea, nausea, stomach pain, vomiting, or a feeling of unusual tiredness or illness, cough, trouble breathing, sore throat, lightheadedness, dizziness, or yellow skin or eyes. When you begin taking abacavir and lamivudine, you will be given a Warning Card which describes symptoms of severe allergic reactions that may be caused by abacavir and lamivudine combination. The warning card also provides information about how to treat these allergic reactions. For your safety, you should carry the warning card with you at all times. If you must stop using abacavir because of an allergic reaction, you should never use the medicine again. Return the unused medicine to your doctor or pharmacist. A worse reaction, possibly even death, can occur if you use the medicine again. Tell your doctor right away if you have ever taken abacavir, especially if you have experienced an allergic reaction to it in the past. Two rare but serious reactions to abacavir and lamivudine are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver. These are more common if you are female, very overweight (obese), or have been taking anti-HIV medicines for a long time. Call your doctor right away if you have more than one of these symptoms: abdominal or stomach discomfort or cramping, dark urine, decreased appetite, diarrhea, general feeling of discomfort, light-colored stools, muscle cramping or pain, nausea, unusual tiredness or weakness, trouble breathing, vomiting, or yellow eyes or skin. When you start taking HIV medicines, your immune system may get stronger. If you have certain infections that are hidden in your body, such as pneumonia or tuberculosis, you may notice new symptoms when your body tries to fight them. If this occurs, tell your doctor right away. abacavir and lamivudine will not keep you from giving HIV to your partner during sex. Make sure you understand and practice safe sex such as using latex condoms, even if your partner also has HIV. Do not share needles, toothbrushes, and razor blades with anyone. abacavir and lamivudine may cause you to have excess body fat. Tell your doctor if you notice changes in your body shape, such as an increased amount of fat in the upper back and neck, or around the chest and stomach area, or a loss of fat from the legs, arms, and face. abacavir and lamivudine may increase your risk of having a heart attack. This is more likely to occur if you already have heart disease, high blood pressure, high cholesterol or fats in the blood, or if you smoke. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. abacavir and lamivudine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Abdominal or stomach pain cough diarrhea fever headache nausea numbness or tingling of the face, feet, or hands pain in the joints pain in the muscles skin rash sore throat swelling of the feet or lower legs unusual feeling of discomfort or illness unusual tiredness or weakness vomiting Incidence not known Blistering, peeling, or loosening of the skin bloating burning, numbness, tingling, or painful sensations chest pain chills constipation convulsions dark urine decreased appetite diarrhea difficulty with swallowing dizziness fast heartbeat fast, shallow breathing feeling of fullness general feeling of discomfort hives or welts, itching indigestion light-colored stools loss of appetite loss of bladder control muscle cramping muscle spasm or jerking of all extremities pains in the stomach, side, or abdomen, possibly radiating to the back pale skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue red, irritated eyes redness of the skin red skin lesions, often with a purple center sleepiness sores, ulcers, or white spots on the lips or in the mouth sudden loss of consciousness swollen, painful, or tender lymph glands in the neck, armpit, or groin tightness in the chest troubled breathing with exertion unsteadiness or awkwardness unusual bleeding or bruising upper right abdominal or stomach pain weakness in the arms, hands, legs, or feet yellow eyes and skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abnormal dreams burning feeling in the chest or stomach fear or nervousness feeling of constant movement of self or surroundings lightheadedness sensation of spinning severe and throbbing headache stomach upset tenderness in the stomach area trouble sleeping Incidence not known Abnormal breathing sounds blurred vision burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings dry mouth flushed, dry skin fruit-like breath odor gaining weight around your neck, upper back, breast, face, or waist hair loss increased hunger increased thirst increased urination muscle weakness sweating swelling or inflammation of the mouth thinning of the hair unexplained weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about abacavir/lamivudine Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 4 Reviews Add your own review/rating Drug class: antiviral combinations Consumer resources Abacavir and lamivudine Other brands: Epzicom Professional resources Abacavir and Lamivudine Tablets (FDA) Abacavir and Lamivudine (Wolters Kluwer) Related treatment guides HIV Infection Nonoccupational Exposure Occupational Exposure} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Lupin Pharmaceuticals, Inc. Teva Pharmaceuticals USA, Inc. Prasco Laboratories Aurobindo Pharma Limited More... Drug Class Antiviral combinations Related Drugs HIV Infection Truvada , Atripla , Norvir , Viread , Isentress , Prezista , Stribild , lamivudine , More... Occupational Exposure Truvada , Atripla , Viread , Isentress , lamivudine , abacavir , tenofovir , Epzicom , More... Nonoccupational Exposure Truvada , Atripla , Viread , lamivudine , abacavir , tenofovir , Epzicom , Reyataz , More... Abacavir / lamivudine Rating 4 User Reviews 10 /10 4 User Reviews 10 Rate it! Abacavir / lamivudine Images Abacavir / lamivudine systemic 600 mg / 300 mg (TV 5382) View larger images Help and Support Looking for answers? Ask a question or go join the abacavir / lamivudine support group to connect with others who have similar interests.} } you may want
place of job abacavir and lamivudine (Oral route) really extraordinary
EmoticonEmoticon