treatments abciximab (Intravenous route) ab-SIX-i-mab Overview Side Effects Professional Interactions Pregnancy More User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Reopro Available Dosage Forms: Solution Therapeutic Class: Platelet Aggregation Inhibitor Pharmacologic Class: Glycoprotein IIb/IIIa Inhibitor Slideshow Inherited Risk: The BRCA Gene Explained Uses For abciximab Abciximab is used to lessen the chance of heart attack in people who need percutaneous coronary intervention (PCI), a procedure to open blocked arteries of the heart. A heart attack may occur when a blood vessel in the heart is blocked by a blood clot. Blood clots can sometimes form during PCI. Abciximab reduces the chance that a harmful clot will form by preventing certain cells in the blood from clumping together. Abciximab is used with aspirin and heparin, which are other medicines used to keep your blood from clotting. abciximab is available only with your doctor's prescription. Before Using abciximab In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For abciximab, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to abciximab or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Studies on abciximab have been done only in adult patients, and there is no specific information comparing use of abciximab in children with use in other age groups. Geriatric Bleeding problems may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults tot the effects of abciximab. It is important that you discuss the use of abciximab with your doctor. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking abciximab, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using abciximab with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Defibrotide Eptifibatide Using abciximab with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Acenocoumarol Alipogene Tiparvovec Alteplase, Recombinant Amtolmetin Guacil Anagrelide Apixaban Ardeparin Argatroban Bemiparin Betrixaban Bivalirudin Bromfenac Bufexamac Celecoxib Certoparin Choline Salicylate Cilostazol Citalopram Clonixin Dabigatran Etexilate Dalteparin Danaparoid Desirudin Desvenlafaxine Dexibuprofen Dexketoprofen Dextran Diclofenac Diflunisal Dipyridamole Dipyrone Drotrecogin Alfa Droxicam Duloxetine Edoxaban Enoxaparin Escitalopram Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Fluoxetine Flurbiprofen Fluvoxamine Fondaparinux Heparin Ibuprofen Indomethacin Ketoprofen Ketorolac Lepirudin Levomilnacipran Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Milnacipran Morniflumate Nabumetone Nadroparin Naproxen Nefazodone Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Parnaparin Paroxetine Phenindione Phenprocoumon Phenylbutazone Piketoprofen Piracetam Piroxicam Proglumetacin Propyphenazone Proquazone Protein C Reviparin Rivaroxaban Rofecoxib Salicylic Acid Salsalate Sertraline Sodium Salicylate Sulindac Tenoxicam Tiaprofenic Acid Ticlopidine Tinzaparin Tolfenamic Acid Tolmetin Valdecoxib Vilazodone Vortioxetine Warfarin Using abciximab with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Vitamin A Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Other Medical Problems The presence of other medical problems may affect the use of abciximab. Make sure you tell your doctor if you have any other medical problems, especially: Aneurysm (swelling in a blood vessel) especially in the head or Blood disease or a history of unusual bleeding or Brain problems which may include bleeding, disease, injury or tumor or If you weigh less than 150 pounds or If you are over 65 years of age or Injury to any part of the body or Liver disease or Stroke The risk of bleeding may be increased Also, tell your doctor if you have received abciximab or heparin before and had a reaction to either of them called thrombocytopenia (a low platelet count in the blood), or if new blood clots formed while you were receiving the medicine. In addition, tell your doctor if you have recently had any bleeding from the stomach, previously had a stroke, recently fallen or suffered a blow to the body or head, or had major medical or dental surgery . These events may increase the risk of serious bleeding when you are taking abciximab. Proper Use of abciximab Dosing The dose of abciximab will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of abciximab. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For injection dosage form: For prevention of blood clots during percutaneous coronary intervention (the procedure to open blocked blood vessels): Adults Initial dose: 250 micrograms (mcg) per kilogram (kg) of body weight injected 10 to 60 minutes before the procedure. Maintenance dose: 0.125 mcg per kg of body weight per minute (maximum of 10 mcg per minute) by IV for 12 hours. Children Use and dose must be determined by your doctor. For patients with unstable angina that will undergo percutaneous coronary intervention within 24 hours: Adults Initial dose: 250 micrograms (mcg) per kilogram (kg) of body weight injected. Maintenance dose: 10 mcg per minute by IV for 18 to 24 hours, ending 1 hour after the procedure. Children Use and dose must be determined by your doctor. Precautions While Using abciximab Tell all of your medical doctors and dentists that you are using abciximab. Check with your doctor immediately if you notice any of the following side effects: Bruising or bleeding, especially bleeding that is hard to stop. Bleeding inside the body sometimes appears as bloody or black, tarry stools, or faintness. Back pain; burning, pricking, tickling, or tingling sensation; leg weakness; numbness; paralysis; or problems with bowel or bladder function. abciximab Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Bleeding blurred vision; confusion; dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; unusual tiredness or weakness Less common Black, tarry stools bleeding gums blood in urine or stools pinpoint red spots on skin unusual bleeding or bruising Rare Chest pain or discomfort chills cough eye pain fever general feeling of illness headache pale skin rapid weight gain shortness of breath slow or irregular heartbeat sneezing sore throat swelling of hands, ankles, feet, or lower legs tightness in chest tingling of hands or feet troubled breathing unusual tiredness wheezing Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More Common Back pain Less common Acid or sour stomach belching burning, crawling, itching, numbness, prickling, pins and needles , or tingling feelings changes in vision delusions dementia fear heartburn indigestion or stomach discomfort, upset or pain mood or mental changes nausea nervousness vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about abciximab Side Effects During Pregnancy Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: glycoprotein platelet inhibitors Consumer resources Abciximab Other brands: ReoPro Professional resources Abciximab (AHFS Monograph) Abciximab (Wolters Kluwer) Related treatment guides High Risk Percutaneous Transluminal Angioplasty} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Glycoprotein platelet inhibitors Related Drugs High Risk Percutaneous Transluminal Angioplasty abciximab , ReoPro , More... Abciximab Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the abciximab support group to connect with others who have similar interests.} } discover
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