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most desirable [1:10 mg/mL). However, standardized techniques for susceptibility testing for antifungal agents have not been established, and results of susceptibility studies do not necessarily correlate with clinical outcome. Abelcet is active in animal models against Aspergillus fumigatus, Candida albicans, C. guillermondii, C. stellatoideae , and C. tropicalis, Cryptococcus sp., Coccidioidomyces sp., Histoplasma sp., and Blastomyces sp. in which end-points were clearance of microorganisms from target organ(s) and/or prolonged survival of infected animals. Drug Resistance Fungal species with decreased susceptibility to amphotericin B have been isolated after serial passage in culture media containing the drug, and from some patients receiving prolonged therapy. Although the relevance of drug resistance to clinical outcome has not been established, fungal species which are resistant to amphotericin B may also be resistant to Abelcet . Slideshow Top 11 Reasons Why You Should Get Your Flu Vaccine Now Abelcet - Clinical Pharmacology Pharmacokinetics The assay used to measure amphotericin B in the blood after the administration of Abelcet does not distinguish amphotericin B that is complexed with the phospholipids of Abelcet from amphotericin B that is uncomplexed. The pharmacokinetics of amphotericin B after the administration of Abelcet are nonlinear. Volume of distribution and clearance from blood increase with increasing dose of Abelcet , resulting in less than proportional increases in blood concentrations of amphotericin B over a dose range of 0.6-5 mg/kg/day. The pharmacokinetics of amphotericin B in whole blood after the administration of Abelcet and amphotericin B desoxycholate are: Pharmacokinetic Parameters of Amphotericin B in Whole Blood in Patients Administered Multiple Doses of Abelcet or Amphotericin B Desoxycholate Pharmacokinetic Parameter Abelcet 5 mg/kg/day for 5-7 days Mean SD Amphotericin B 0.6 mg/kg/day for 42 days a Mean SD Peak Concentration ( μg/mL) 1.7 0.8 (n=10) b 1.1 0.2 (n=5) Concentration at End of Dosing Interval (μg/mL) 0.6 0.3 (n=10 b 0.4 0.2 (n=5) Area Under Blood Concentration-Time Curve (AUC 0-24h ) (μg*h/mL) 14.0 7.0 (n=14) b,c 17.1 5 (n=5) Clearance (mL/h*kg) 436.0. 188.5 (n=14) b,c 38.0 15 (n=5) Apparent Volume of Distribution (Vd area ) (L/kg) 131.0. 57.7 (n=8) c 5.0. 2.8 (n=5) Terminal Elimination Half-Life (h) 173.4 78.0 (n=8) c 91.1 40.9 (n=5) Amount Excreted in Urine Over 24 h After Last Dose (% of dose) d 0.9 0.4 (n=8) c 9.6 2.5 (n=8) a Data from patients with mucocutaneous leishmaniasis. Infusion rate was 0.25 mg/kg/h. b Data from studies in patients with cytologically proven cancer being treated with chemotherapy or neutropenic patients with presumed or proven fungal infection. Infusion rate was 2.5 mg/kg/h. c Data from patients with mucocutaneous leishmaniasis. Infusion rate was 4 mg/kg/h. d Percentage of dose excreted in 24 hours after last dose. The large volume of distribution and high clearance from blood of amphotericin B after the admistration of Abelcet probably reflect uptake by tissues. The long terminal elimination half-life probably reflects a slow redistribution from tissues. Although amphotericin B is excreted slowly, there is little accumulation in the blood after repeated dosing. AUC of amphotericin B increased approximately 34% from day 1 after the administration of Abelcet 5 mg/kg/day for 7 days. The effect of gender or ethnicity on the pharmacokinetics of Abelcet has not been studied. Tissue concentrations of amphotericin B have been obtained at autopsy from one heart transplant patient who received three doses of Abelcet at 5.3 mg/kg/day: Concentration in Human Tissues Organ Amphotericin B Tissue Concentration (µg/g) Spleen 290.0 Lung 222.0 Liver 196.0 Lymph Node 7.6 Kidney 6.9 Heart 0 5. Brain 1.6 This pattern of distribution is consistent with that observed in preclinical studies in dogs in which greatest concentrations of amphotericin B after Abelcet administration were observed in the liver, spleen, and lung; however, the relationship of tissue concentrations of amphotericin B to its biological activity when administered as Abelcet is unknown. Special Populations Hepatic Impairment: The effect of hepatic impairment on the disposition of Abelcet is not known. Renal Impairment: The effect of renal impairment on the disposition of Abelcet is not known. The effect of dialysis on the elimination of Abelcet has not been studied; however, amphotericin B is not removed by hemodialysis when administered as amphotericin B desoxycholate. Pediatric and Elderly Patients: The pharmacokinetics and pharmacodynamics of pediatric patients ( 16 years of age) and elderly patients ( 65 years of age) have not been studied. Indications and Usage for Abelcet Abelcet is indicated for the treatment of invasive fungal infections in patients who are refractory to or intolerant of conventional amphotericin B therapy. This is based on open-label treatment of patients judged by their physicians to be intolerant to or failing conventional amphotericin B therapy (See DESCRIPTION OF CLINICAL STUDIES). DESCRIPTION OF CLINICAL STUDIES Fungal Infections Data from 473 patients were pooled from three open-label studies in which Abelcet was provided for the treatment of patients with invasive fungal infections who were judged by their physicians to be refractory to or intolerant of conventional amphotericin B, or who had preexisting nephrotoxicity. Results of these studies demonstrated effectiveness of Abelcet in the treatment of invasive fungal infections as a second line therapy. Patients were defined by their individual physician as being refractory to or failing conventional amphotericin B therapy based on overall clinical judgement after receiving a minimum total dose of 500 mg of amphotericin B. Nephrotoxicity was defined as a serum creatinine that had increased to >2.5 mg/dL in adults and >1.5 mg/dL in pediatric patients, or a creatinine clearance of] FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Manufacturer Sigma-Tau Pharmaceuticals, Inc. Drug Class Polyenes Related Drugs polyenes nystatin , Mycostatin , amphotericin b , AmBisome Candidemia fluconazole , Diflucan , itraconazole , voriconazole , amphotericin b , Sporanox , More... Coccidioidomycosis ketoconazole , fluconazole , Diflucan , Nizoral , itraconazole , amphotericin b , More... Blastomycosis ketoconazole , fluconazole , Diflucan , Nizoral , itraconazole , voriconazole , More... 5 more conditions... Abelcet Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! come across


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brilliant Abelcet Generic Name: amphotericin b lipid complex (Intravenous route, Injection route) am-foe-TER-i-sin B LIP-id KOM-plex Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Abelcet Available Dosage Forms: Powder for Solution Suspension Therapeutic Class: Antifungal Chemical Class: Polyene Slideshow A Joint Effort: A Provider's Guide To Orthopedic Pain Options Uses For Abelcet Amphotericin B lipid complex is an antifungal medicine. It is used to help the body overcome serious infections caused by fungus. This medicine is available only with your doctor's prescription. Before Using Abelcet In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults. Geriatric This medicine has been tested in a limited number of patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults. Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Cyclosporine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Blood transfusion Amphotericin B lipid complex may cause side effects affecting the lungs Kidney disease Amphotericin B lipid complex may make your kidney problems worse Proper Use of Abelcet Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For injection dosage form: For treatment of serious infection caused by fungus: Adults and children 5 milligrams per kilogram (2.27 mg per pound) of body weight per day, injected slowly into a vein. Abelcet Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur: More common Chills and fever headache nausea and vomiting Less common Difficulty in breathing sore throat and fever unusual bleeding or bruising unusual tiredness and weakness Rare Increased or decreased urination Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Diarrhea loss of appetite stomach pain Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Abelcet (amphotericin b lipid complex) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons 0 Reviews Add your own review/rating Drug class: polyenes Consumer resources Abelcet Professional resources Abelcet (FDA) Related treatment guides Aspergillosis, Aspergilloma Aspergillosis, Invasive Blastomycosis Candidemia ... +4 more Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Manufacturer Sigma-Tau Pharmaceuticals, Inc. Drug Class Polyenes Related Drugs Candidemia fluconazole , Diflucan , itraconazole , voriconazole , amphotericin b , Sporanox , More... Coccidioidomycosis ketoconazole , fluconazole , Diflucan , Nizoral , itraconazole , amphotericin b , More... Blastomycosis ketoconazole , fluconazole , Diflucan , Nizoral , itraconazole , voriconazole , More... Cryptococcosis fluconazole , Diflucan , itraconazole , amphotericin b , Sporanox , AmBisome , More... 4 more conditions... Abelcet Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the Abelcet support group to connect with others who have similar interests. without borderlines


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penal complex (*this news item will not be available after 01/25/2018) By Robert Preidt Friday, October 27, 2017 THURSDAY, Oct. 26, 2017 (HealthDay News) -- Planning to have open heart surgery anytime soon? You might want to ask your cardiologist to book an afternoon slot in the OR. New research shows that heart operations performed in the afternoon produced better outcomes than those done in the morning. Because afternoon heart surgery syncs with the body's circadian clock (the internal body clock that controls when people sleep, eat and wake up), it reduces the risk of heart damage, the French researchers said. "Currently, there are few other surgical options to reduce the risk of post-surgery heart damage, meaning new techniques to protect patients are needed," said study author Dr. David Montaigne, a professor at the University of Lille. In one part of the study, his team tracked the medical records of nearly 600 people who had heart valve replacement surgery for 500 days, to identify any major cardiac events such as a heart attack, heart failure or death from heart disease. Half had surgery in the morning while the other half had it in the afternoon. The risk of a major cardiac event was 50 percent lower among patients who had surgery in the afternoon than in those who had surgery in the morning. That would work out to one less major cardiac event per 11 patients who have afternoon surgery, the researchers said. In another part of the study, the researchers monitored the health of 88 heart valve replacement surgery patients until they left the hospital. During the average follow-up of 12 days, patients who had afternoon surgery had less heart tissue damage than those who had morning surgery. The researchers then tested 30 heart tissue samples from this group of patients and found that samples from afternoon surgery patients more quickly regained their ability to contract when put in conditions that replicated the heart refilling with blood. Genetic analysis of the heart tissue samples also revealed that 287 genes linked to the circadian clock were more active in the samples from afternoon surgery patients than those from morning surgery patients. That suggests that the heart is affected by the circadian clock, and that open heart surgery outcomes reflect the heart's poorer ability to repair in the morning, the researchers said. The findings were published Oct. 26 in The Lancet medical journal. "Our study found that post-surgery heart damage is more common among people who have heart surgery in the morning, compared to the afternoon," Montaigne said in a journal news release. "Our findings suggest this is because part of the biological mechanism behind the damage is affected by a person's circadian clock, and the underlying genes that control it. As a result, moving heart surgery to the afternoon may help to reduce a person's risk of heart damage after surgery," he added. Montaigne and his colleagues also said it may be possible to develop drugs that can influence circadian clock-related genes to protect the heart during surgery. SOURCE: The Lancet , news release, Oct. 26, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on After Surgery Recent Health News you ought to be


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remedies (*this news item will not be available after 01/25/2018) By Alan Mozes Friday, October 27, 2017 FRIDAY, Oct. 27, 2017 (HealthDay News) -- Botox injections may help bring relief to children suffering from migraines, a small study suggests. Botox (botulinum toxin) appears to reduce the frequency of migraines and shorten the length of episodes when they do occur, while also diminishing migraine pain. At the moment, Botox is only approved as an adult migraine treatment. And the new findings are based on testing among just nine children, aged 8 to 17. But the results raise hope that a new alternative therapy for pediatric migraines is on the horizon, given that only a single preventive migraine medication -- topiramate -- is currently approved for the treatment of adolescent patients. "When children and teens have migraine pain, it can severely affect their lives and ability to function," said study author Dr. Shalini Shah, chief of the division of pain medicine at the University of California, Irvine, "They miss school, their grades suffer and they are left behind, often unable to reach their full potential," she added explained in an American Society of Anesthesiologists' news release. "Clearly, there is a need for an alternative treatment for those who haven't found relief. Shah said that after treatment with Botox, "we saw improvement in functional aspects in all of the children and teens. In fact, one patient was hospitalized monthly for her migraine pain prior to Botox treatment and was expected to be held back in school. After treatment, she only has one or two migraines a year, and is excelling in college." The study team said that prior to Botox injections, the participating patients experienced migraines between roughly eight and 30 times per month. The kids and teens were given Botox shots to the front and back of the head and the neck every 12 weeks for five years. Once treated, the study volunteers had migraines between two and 10 times a month. Migraine duration also fell from between a half hour and a full day, to 15 minutes to seven hours. Reported pain also fell significantly, the researchers said. Though no severe side effects were reported, another study is already being launched. Shah presented the findings this week at a meeting of the American Society of Anesthesiologists in Boston. Findings presented at meetings are typically viewed as preliminary if they haven't been published in a peer-reviewed journal. SOURCE: American Society of Anesthesiologists, news release, Oct. 23, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Migraine Teen Health Recent Health News gives you


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superior (*this news item will not be available after 01/26/2018) By Robert Preidt Saturday, October 28, 2017 SATURDAY, Oct. 28, 2017 (HealthDay News) -- Did you spend the hot, sweltering days of summer sitting in front of an air conditioner? Then fall is a probably a good time for you to get up and get moving, medical experts say. Why is now a good time? If you start now, you'll be well into your exercise program, which will help counter the overeating that typically occurs during the holiday season, according to UPMC Pinnacle, a health care system at the University of Pittsburgh Medical Center. In most of the United States, the fall means cooler temperatures and fewer bugs, which means ideal conditions for walking in local parks or going for hikes in state parks. Having a dog can help motivate you to get out for regular walks. If a dog isn't an option, find a human walking partner to help keep you motivated. And you don't need to limit yourself to walking. Other options include cycling, jogging -- even dancing. While watching TV, use exercise bands or light weights for some seated strength training, or do standing exercise routines. If you haven't exercised in a long time or have health issues or concerns, you should talk to your doctor before starting a new exercise routine. SOURCE: UPMC Pinnacle, news release, Oct. 20, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Benefits of Exercise Exercise and Physical Fitness Recent Health News of one


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you take (*this news item will not be available after 01/28/2018) By Robert Preidt Monday, October 30, 2017 MONDAY, Oct. 30, 2017 (HealthDay News) -- High school students who use electronic cigarettes are more likely to start smoking regular cigarettes, a new Canadian study finds. "Youth may be trying e-cigarettes before smoking because they are easier to access: until recently, youth could legally purchase e-cigarettes without nicotine, whereas regular cigarettes cannot be sold to young people under 18 years of age," said study author David Hammond. The study included more than 44,000 students in grades 9 through 12 at dozens of schools in the Canadian provinces of Ontario and Alberta. Students who used e-cigarettes within 30 days before the start of the study were more likely to have started and still be smoking regular cigarettes a year later. The finding is consistent with previous studies. However, this study also found a slight decline in the smoking rate among students. This suggests that if e-cigarettes are leading to use of regular cigarettes, the effect may be modest, according to the authors of the study published Oct. 30 in the Canadian Medial Association Journal . "While our study provides strong evidence that e-cigarettes are associated with smoking initiation among youth, the association is unclear," Hammond said in a journal news release. "E-cigarettes may help to re-normalize smoking; however, the association between e-cigarettes and smoking may simply reflect common factors rather than a causal effect: the same individual and social risk factors that increase e-cigarette use may also increase the likelihood of youth smoking," Hammond explained. He's with the School of Public Health and Health Systems at the University of Waterloo in Ontario. There are some important differences to note between U.S. and Canadian e-cigarette laws. In Canada, teens can purchase non-nicotine e-cigarettes before they're 18. As for e-cigarettes with nicotine, those are more tightly regulated in Canada, and aren't sold in retail outlets such as supermarkets. They can only be purchased at "vape" shops and online. SOURCE: Canadian Medical Association Journal , news release, Oct. 30, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on E-Cigarettes Smoking and Youth Recent Health News agency


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hung out (*this news item will not be available after 01/28/2018) By Alan Mozes Monday, October 30, 2017 MONDAY, Oct. 30, 2017 (HealthDay News) -- One in every 30 children in the United States has high blood pressure. Now, new guidelines from the American Academy of Pediatrics may help doctors screen children 3 years and older for the condition. "We are seeing it at far younger ages than we used to," said Dr. Thomas Dispenza, a cardiologist with Penn State Children's Heart Group. "As obesity rates have risen, we have also seen more complications from it." But "detection rates are shockingly low. Three-quarters of cases are overlooked, and that's a real problem," Dispenza said in a Penn State Health news release. Children with high blood pressure can develop the same long-term health problems as adults. "It can set kids up for strokes later in life by damaging the blood vessels," Dispenza said. The guidelines encourage doctors to check blood pressure at every well-child visit. For better accuracy, medical providers should wait three to five minutes before taking a blood pressure reading, so that the patient has time to relax and calm down after arriving in an exam room. The child should also place both feet flat on the floor, with the back supported, and should avoid talking. Right arm readings are preferable. The guidelines are intended to help identify signs that warrant further investigation, not for rendering a final diagnosis. The academy hopes the guidelines will also assist doctors in picking up indications of other illnesses. For example, high blood pressure among children under 5 could be an indication of kidney disease or an endocrine condition. In children aged 6 and older, it may indicate hardening of the arteries. If a high blood pressure diagnosis is made, children should be slowly transitioned to a diet that is low-sodium and composed primarily of plant-based foods (such as the DASH diet), the academy advises. SOURCE: Penn State Health, news release, Oct. 19, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Children's Health High Blood Pressure Recent Health News in the present day


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(*this news item will not be available after 01/29/2018) By Robert Preidt Tuesday, October 31, 2017 TUESDAY, Oct. 31, 2017 (HealthDay News) -- An outbreak of a potentially deadly bacteria linked to contaminated puppy poop has spread to 15 states, a new federal report shows. These multidrug-resistant Campylobacter infections have now sickened 67 people. In the latest update from the U.S. Centers for Disease Control and Prevention, the agency said cases rose from 39 in mid-September to 67 reported by Oct. 30. Ninety-three percent of these infections have been connected to puppies sold at Petland stores. "Evidence suggests that puppies sold through Petland are a likely source of this outbreak," the CDC said in a news release issued in September. "Petland is cooperating with public health and animal health officials to address this outbreak." Of the 62 patients for whom there was available information, 17 (27 percent) have been hospitalized, the CDC said in an Oct. 30 news release. Campylobacter infections linked to the puppies have now been reported between September 2016 and October 2017 in Florida, Georgia, Illinois, Kansas, Maryland, Missouri, New Hampshire, New York, Ohio, Oklahoma, Pennsylvania, Tennessee, Utah, Wisconsin and Wyoming, the CDC said. Ohio has the most cases, with 24 infections reported. Campylobacter is a bacteria that causes people to develop diarrhea (sometimes bloody), cramping, abdominal pain and fever within two to five days of exposure to the organism, said Dr. Sophia Jan, director of general pediatrics at Cohen Children's Medical Center, in New Hyde Park, N.Y. This is a common cause of diarrhea in the United States, she said. "The illness typically lasts about a week without treatment," Jan said. But for people with compromised immune systems, Campylobacter infections can be life-threatening, she added. Most cases in humans occur from eating raw or undercooked chicken, or eating foods that have been cross-contaminated by infected poultry products, Jan said. However, humans can get infected from contact with the stool of an infected puppy, she added. Almost all of the people sickened in this outbreak have been Petland employees, while others had either bought a Petland puppy, shopped at Petland or visited someone who had purchased a puppy from Petland, the CDC said. Infected dogs may or may not show signs of illness -- such as diarrhea, vomiting or a fever -- so it's important to take precautions when around dogs, the CDC advises. To prevent catching Campylobacter from dogs, the CDC recommends that you: Wash your hands thoroughly after touching dogs, their poop or their food. Take extra care that children wash their hands carefully after playing with puppies or dogs. Pick up and dispose of dog poop, especially in areas where children might play. Contact your veterinarian if you notice any signs of illness in your puppy or dog. SOURCES: Sophia Jan, M.D., director, general pediatrics, Cohen Children's Medical Center, New Hyde Park, N.Y.; U.S. Centers for Disease Control and Prevention, news releases, Sept. 11, Oct. 3, and Oct. 30, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Bacterial Infections Pet Health Recent Health News expenditures


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simply (*this news item will not be available after 01/28/2018) By Mary Elizabeth Dallas Monday, October 30, 2017 MONDAY, Oct. 30, 2017 (HealthDay News) -- Kids may encounter some scary surprises on Halloween, but they shouldn't get injured while they go trick-or-treating. However, U.S. emergency departments reported more than 700,000 Halloween-related injuries involving children and teens between 2007 and 2016. In many cases, kids are sustaining head or hand injuries, according to the National Electronic Injury Surveillance System. "It's essential that parents talk to kids about the importance of safety while trick-or-treating in their neighborhoods," said Dr. Louise Reid Boyce Nichols, a pediatric orthopaedic surgeon in Wilmington, Del. "A common danger is traffic. Both children and adults should always be aware of their surroundings, avoid distracted walking and watch out for traffic," Nichols noted in a news release from the American Academy of Orthopaedic Surgeons (AAOS). There are several ways children, teens and parents can avoid injuries on Halloween. Experts from the AAOS and the Pediatric Orthopaedic Society of North America recommend the following: Stick to sidewalks. Avoid cutting across people's yards or driveways. It's also important to always obey traffic signals and use crosswalks when crossing the street. Be visible. Adding reflective tape to costumes and goodie bags can help make sure cars and other pedestrians can see you. Dressing children in brightly colored costumes also makes them more visible once the sun goes down. Consider costume safety. Children and teens should not wear masks, face paint, hats or other accessories that block their vision. Costumes should also be flame-resistant. Make sure children wear costumes that fit. Wearing clothing that is too long or big increases the likelihood that children will trip and fall. Pick the right shoes. Trick-or-treaters should wear comfortable, sturdy shoes they can walk in without slipping or falling. Skip dark houses. Remind trick-or-treaters to only approach houses that are well-lit. Bring a flashlight. Children and parents should carry flashlights to ensure they can see and be seen on Halloween. Flashlights should not be pointed above chest height. This can block the vision of drivers or pedestrians. Be mindful of pets. Dogs and other pets may be anxious if strangers approach their house. Don't forget a phone. Children or a supervising adult should carry a cellphone while trick-or-treating, in case of an emergency. Don't let kids go out alone. Children should always be supervised by a responsible adult. SOURCE: American Academy of Orthopaedic Surgeons, news release, Oct. 26, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Child Safety Recent Health News a designated


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is provided with Doctors Urged to Discuss Cord Blood Donations Early in Pregnancy may be

started Doctors Urged to Discuss Cord Blood Donations Early in Pregnancy no use
 
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status quo (*this news item will not be available after 01/28/2018) By Robert Preidt Monday, October 30, 2017 MONDAY, Oct. 30, 2017 (HealthDay News) -- A leading group of U.S. pediatricians is encouraging parents to donate to public cord blood banks after the birth of their children. The past decade has seen an increase in the use of umbilical cord blood for stem cell transplants that can save children with fatal or debilitating diseases, the American Academy of Pediatrics says in a new policy statement. "Most parents will never need cord blood for their own family's use, but they can donate this precious lifesaving gift to benefit others," said statement lead author Dr. William Shearer. He is a professor of pediatrics and immunology at Baylor College of Medicine in Houston. "We expect the need for these therapies that rely on stem cell transplantation to grow, and would like families to understand the choices they have," he said in an academy news release. Cord blood is an excellent source of stem cells. It's taken from the placenta of healthy newborns and used most often in stem cell transplantations to treat fatal diseases such as cancer, blood disorders and immune deficiencies, the doctors' group says. Donating cord blood is safe for the baby and doesn't interfere with labor and delivery, according to the statement. By 2013, more than 30,000 stem cell transplants had been performed worldwide using cord blood. Parents must register in advance to donate cord blood so that a collection kit can be sent for use after the baby's delivery. Because of this, doctors should talk with expectant parents about a donation during an early prenatal visit, the AAP says. "The research is evolving in this area, which is exciting news for patients whose lives may someday depend on a donation of cord blood," Shearer said. "The hope is that more doctors will discuss the options with expectant parents well in advance of their baby's birth, so they understand the tremendous potential to help others in medical need." The statement authors also distinguish between public cord blood banks, which match individuals in need worldwide, and private ones. Private cord blood banks store cord blood for a donor family's own use, if needed, "although there is little evidence supporting this use unless a family shares a known genetic defect," the statement says. Also, while there's no charge for donating to a public cord blood bank, private operations charge an initial fee of $1,350 to $2,300. The private banks' yearly maintenance charges range from $100 to $175. The statement was published online Oct. 30 in the journal Pediatrics . SOURCE: American Academy of Pediatrics, news release, Oct. 30, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Stem Cells Recent Health News is trying


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the apparent Acetaminophen in Pregnancy Tied to ADHD Risk in Kids predict

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apologize (*this news item will not be available after 01/28/2018) Monday, October 30, 2017 MONDAY, Oct. 30, 2017 (HealthDay News) -- Acetaminophen is considered the go-to pain medication during pregnancy. But a new study adds to evidence linking the drug to an increased risk of behavioral issues in kids. Researchers in Norway found that among nearly 113,000 children, those whose mothers used acetaminophen during pregnancy were slightly more likely to be diagnosed with attention deficit hyperactivity disorder (ADHD). The link was, however, confined to longer-term use -- particularly a month or longer. When moms used acetaminophen for 29 days or more during pregnancy, their kids were twice as likely to be diagnosed with ADHD, versus women who did not use the drug. On the other hand, when expectant moms used the drug for a week or less, their kids showed a slightly decreased risk of ADHD. Acetaminophen is best known by the brand name Tylenol, but it's an active ingredient in many pain relievers. The new study, led by researcher Eivind Ystrom from the Norwegian Institute of Public Health in Oslo, is not the first to suggest a connection between prenatal acetaminophen and ADHD. But experts said it's still hard to definitively pin the blame on the medication. "That's the dilemma," said Christina Chambers, co-director of the Center for Better Beginnings at the University of California, San Diego. Around half of pregnant women use acetaminophen at some point, so it's important to understand any risks, according to Chambers, who was not involved in the study. But with a study like this, she explained, it's difficult to know whether factors other than acetaminophen are to blame -- including the underlying conditions the women had. According to the study researchers, longer-term use was tied to ADHD whether women used it for pain, fevers or infections. But if a woman was using the medications for weeks to treat a fever or infection, that indicates she was quite ill, Chambers pointed out. And if she took the drug for chronic pain, Chambers said, that raises the question of what effects the pain condition could have on her pregnancy. For now, Chambers stressed that pregnant women should not be scared off from using acetaminophen for a fever -- since an untreated fever could carry risks. "The last thing we'd want, heading into flu season, is for women not to use acetaminophen to get a fever down," she said. "This study," Chambers added, "suggests that if there is a causal association between acetaminophen and ADHD, it's with more-chronic use." Overall, more than 2,200 children in the study were diagnosed with ADHD -- or about 2 percent of the whole group. The risk was just over twofold higher among kids whose mothers had used acetaminophen for 29 days or more during pregnancy. Why would the medication affect ADHD risk? There are potential "biologically plausible" explanations, Chambers said. The drug might, for instance, interfere with maternal hormones that are important for fetal brain development. But even if long-term acetaminophen does influence ADHD development, Chambers said, this study suggests it's a "modest" effect. "The risk to any one woman would be small," she said. That said, Chambers pointed to a bigger-picture issue: Very few drugs have actually been studied in pregnant women, and fairly little is known about the safety of using any medication prenatally. The study was published online Oct. 30 in the journal Pediatrics . Dr. Mark Wolraich, a professor of pediatrics at the University of Oklahoma Health Sciences Center, wrote an editorial accompanying the study. He agreed that the study points only to an association between acetaminophen and ADHD, which might reflect a "third factor" at play, such as the underlying condition that caused the women to take the drug. Plus, Wolraich explained, many factors might affect the development of ADHD. The evidence is "much stronger" for a familial influence, since the disorder tends to run in families, he noted. Still, Wolraich said, pregnant women may want to be "overly cautious" about using acetaminophen for any extended time. He suggested that women talk their doctor before using any medications. SOURCES: Christina Chambers, Ph.D., M.P.H., professor, department of pediatrics, and co-director, Center for Better Beginnings, University of California, San Diego; Mark Wolraich, M.D., professor, pediatrics, Child Study Center, University of Oklahoma Health Sciences Center, Oklahoma City; Oct. 30, 2017, Pediatrics , online HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Attention Deficit Hyperactivity Disorder Pregnancy and Medicines Recent Health News flattening


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task Want to Avoid Salt? Turn Up the Spice it's also

twisted up Want to Avoid Salt? Turn Up the Spice shade
 
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bobbing up (*this news item will not be available after 01/29/2018) Tuesday, October 31, 2017 TUESDAY, Oct. 31, 2017 (HealthDay News) -- If your taste buds lean toward spicy, you might be doing your heart a favor, new research suggests. Spicy foods may increase salt sensitivity, thereby dampening the desire to consume heart-harming salty food, researchers in China say. "High salt intake increases blood pressure and contributes to cardiovascular disease," said study author Dr. Zhiming Zhu. "Thus, reducing salt intake is very important for health. "We find that the enjoyment of spicy foods significantly reduced individual salt preference, daily salt intake and blood pressure," he added. Zhu is director of Daping Hospital's Center for Hypertension and Metabolic Diseases at Third Military Medical University in Chongqing. The research team conducted a mouse study alongside a human trial of more than 600 Chinese adults. Both correlated blood pressure levels with intake of spicy and salty dishes. Foods like chili that dial up the heat essentially change the way the brain interprets salt, or sodium, intake, explained Zhu. As spice consumption goes up, the result is a notably reduced craving for salt, according to his study. The World Health Organization (WHO) has identified salt reduction as the "key dietary target" in a push to cut the risk of dying from non-communicable illnesses by 2025. Zhu and his associates pointed out that people in most of the world routinely take in far more than the WHO's recommended limit of 5 grams of dietary salt a day. The American Heart Association advises consuming no more than a single teaspoon of salt -- about 2,300 milligrams of sodium -- a day. In the United States, three-quarters of all sodium consumption comes from processed and packaged foods and/or restaurant meals. For the new study, the researchers assessed participants' preferences for salty and spicy flavors, and linked those tendencies to blood pressure levels. The biggest consumers of spicy food were found to consume about 2.5 fewer grams of salt daily, compared to those with the blandest palates. The spice lovers also had systolic (upper) and diastolic (bottom) blood pressure levels that were 8 mm Hg and 5 mm Hg lower, respectively, on average, the findings showed. Participants were then divided into two dietary groups and underwent brain scans. One group ate a diet spiked with capsaicin, the major spicy compound in chili pepper. The other group consumed their usual diet. Previous research suggested that capsaicin at low levels -- not enough to cause a burning sensation on the tongue -- might enhance saltiness. Imaging scans showed the capsaicin group experienced a significant increase in activity in a brain region central to the processing of taste. That region was also activated by salt. That overlap, in turn, appeared to diminish the desire to consume salty food, the researchers said. A related experiment conducted with mice confirmed a similar impact on the brain and salt desire. According to Zhu, the study provides "insights for the enjoyment of spicy flavor as a promising behavioral intervention for reducing high salt intake and blood pressure." But another doctor said the heart benefits of a spicy diet remain to be seen. Dr. Gregg Fonarow is co-director of preventative cardiology at the University of California, Los Angeles. He said high blood pressure is a leading contributor to heart attacks, strokes, heart failure and kidney failure. However, "further studies are needed to determine if increased consumption of spicy food would have a favorable impact on health," Fonarow said. The findings were released online Oct. 31 in the journal Hypertension . SOURCES: Zhiming Zhu, M.D., professor, medicine, and director, Center for Hypertension and Metabolic Diseases, Daping Hospital, Third Military Medical University, Chongqing, China; Gregg Fonarow, M.D., director, Ahmanson-UCLA Cardiomyopathy Center, and co-director, UCLA Preventative Cardiology Program, and co-chief, UCLA Division of Cardiology, Los Angeles; Oct. 31, 2017, Hypertension , online HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on High Blood Pressure Sodium Recent Health News satisfactory


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and adaptability How Your Thyroid Could Be Working Against Your Heart really unusual

an additional How Your Thyroid Could Be Working Against Your Heart employer
 
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is a part (*this news item will not be available after 01/29/2018) Tuesday, October 31, 2017 TUESDAY, Oct. 31, 2017 (HealthDay News) -- The tiny thyroid gland could have a big impact on heart health, new research suggests. Middle-aged and older adults with an elevated thyroid hormone may be at higher risk of heart disease and death, researchers found. In the new Dutch study, high and even high-normal levels of a hormone called free thyroxine (FT4) doubled the odds of having calcification of the coronary arteries. This can be a sign of atherosclerosis, commonly called hardening of the arteries. Higher FT4 levels were also linked to an 87 percent greater risk of having a heart attack or stroke and twice the risk of dying from one. "High FT4 is indicative of an overactive thyroid," explained lead researcher Dr. Arjola Bano, of Erasmus University in Rotterdam. FT4 is produced in the thyroid gland at the front of the neck. It helps control the body's rate of energy use, she said. Atherosclerosis means you have fatty deposits called plaque that can clog arteries. As plaque builds up, the artery narrows, reducing blood flow. Atherosclerosis can progress from thickening and hardening of the artery walls to heart disease, stroke and death, Bano said. "Our findings suggest that FT4 measurement can help identify people at increased risk of atherosclerotic events," she added. But before doctors start testing people for their FT4 levels, the findings need confirmation in broader population groups, Bano said. This research was restricted to mostly white participants aged 45 or older. One doctor who reviewed the findings agreed that more study is needed. This study shows an association, but doesn't prove that FT4 boosts the risk for heart disease, said Dr. Byron Lee, director of electrophysiology laboratories at the University of California, San Francisco. "The FT4 could be the cause or simply a marker," Lee said. "Either way, this warrants further exploration, and patients with high FT4 should be on the lookout." Dr. Minisha Sood is an endocrinologist at Lenox Hill Hospital in New York City who also reviewed the findings. She explained that "thyroid hormone is known to increase production of damaging compounds and to foster an environment in the body" that encourages blood clots. "In an environment of inflammation, which is also possibly a contribution by high thyroid hormone levels," this could help lead to heart disease, Sood said. But she too stressed that the study couldn't yet prove cause and effect. For the study, Bano and her colleagues tracked data on more than 9,400 participants in the Rotterdam Study, an ongoing research project in the Netherlands. Average age of the participants was 65. The researchers looked at two types of hormones -- thyroid-stimulating hormone and FT4. They also looked for evidence of atherosclerosis and death from heart disease, stroke or other arterial disease. In addition, they evaluated coronary artery calcification scores, to determine if patients had atherosclerosis without symptoms. Follow-up averaged nearly nine years. During that time, 612 patients died of heart disease, while 934 had a heart attack or stroke, the researchers found. The team concluded that mechanisms other than traditional heart risk factors might have played a role in those outcomes. Perhaps preventive measures targeting thyroid function could help reduce heart attack and stroke rates, they suggested. The report was published online Oct. 31 in the journal Circulation Research . SOURCES: Arjola Bano, M.D., M.Sc., D.Sc., researcher, internal medicine and epidemiology, Erasmus University, Rotterdam, the Netherlands; Byron Lee, M.D., professor, medicine, and director, electrophysiology laboratories and clinics, University of California, San Francisco; Minisha Sood, M.D., endocrinologist, Lenox Hill Hospital, New York City; Oct. 31, 2017, Circulation Research , online HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Heart Diseases Recent Health News inability


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break day Even Partial Breast-Feeding for First Few Months Lowers SIDS Risk sizable of style

unique Even Partial Breast-Feeding for First Few Months Lowers SIDS Risk end result
 
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significant (*this news item will not be available after 01/29/2018) Tuesday, October 31, 2017 TUESDAY, Oct. 31, 2017 (HealthDay News) -- New research confirms that breast-feeding for two to four months of a newborn's life can significantly reduce the risk of sudden infant death syndrome (SIDS). But the study also found moms don't need to breast-feed exclusively to reap that benefit. Even partial breast-feeding will do, the 20-region study found. "What is, perhaps, surprising is that there does not appear to be any benefit of exclusive breast-feeding over partial breast-feeding in relation to SIDS, though there are many other benefits associated with exclusive breast-feeding," explained study author John Thompson, from New Zealand's University of Auckland. The analysis included research from eight major international studies. The researchers reviewed over 2,200 SIDS case patients and over 6,800 "control" infants. There was great variability in the rates of any breast-feeding and exclusive breast-feeding, the findings showed. While the research concluded that breast-feeding for at least two months was associated with half the risk of SIDS, breast-feeding for four months provided even greater protection, and continuing after that time provided further small increases. "The peak incidence of SIDS is from two to four months, so this may be the most critical period in terms of the protective effect of breast-feeding," Thompson said. For moms who struggle with breast-feeding, this research may provide a great comfort, knowing that some breast milk is better than none, said Dr. Jennifer Kurtz. She is chief of neonatology at Long Island Jewish Forest Hills in New York City. "A lot of moms really struggle with breast-feeding, and after those first two months they may not be able to exclusively breast-feed," Kurtz explained. "Many don't have great milk supplies to begin with, and as the baby grows they need more milk and the moms aren't able to keep up with the demand," she said. "Or, moms may also struggle if they need to go back to work. For a lot of working women it's stressful to carry a pump and create a schedule. With some jobs it's not easy to set aside time to pump, and it really becomes a challenge," Kurtz added. It's still unclear how breast-feeding might offer protective effects against SIDS, but there are several theories, the study authors said. Some research has indicated that breast-fed infants are more easily aroused from sleep than formula-fed infants, which might help them to wake if they're having trouble breathing. Differences have also been found in a mother's response to her infant's behavioral cues, depending on feeding mode, which may also affect the baby's sleep and arousal patterns. Additionally, research has shown that breast-feeding provides immune benefits that help prevent viral infections. Such infections are associated with an increased risk of SIDS, the study authors said. Whatever the reason, "this (study) provides very strong evidence of the benefits of breast-feeding in relation to the protective effects with SIDS," Thompson noted. "This will hopefully provide more emphasis on public health efforts to increase the initiation and continuation of breast-feeding around the world," he added. Both Thompson and Kurtz pointed out that while breast-feeding is preferable for the first four months to help decrease the risk of SIDS, it shouldn't stop there, if possible. They advised following the American Academy of Pediatrics' recommendations that breast-feeding continue for at least 12 months, and thereafter for as long as mother and baby desire. "Breast-feeding is good for many reasons," Kurtz said. "You are passing on immunoglobulins for children that help prevent them from getting illnesses, it's a great bonding experience, and children that are breast-fed are less likely to be obese or get diabetes." The study was published online Oct. 30 in the journal Pediatrics . SOURCES: John M.D. Thompson, Ph.D., University of Auckland, New Zealand; Jennifer Kurtz, D.O., chief of neonatology, Long Island Jewish Forest Hills, Forest Hills, N.Y.; Oct. 30, 2017, Pediatrics , online HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Breastfeeding Infant and Newborn Care Recent Health News i believed


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equal U.S. Preemie Birth Rates Rise 2 Years in a Row without boundary lines

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strong point (*this news item will not be available after 01/30/2018) By Robert Preidt Wednesday, November 1, 2017 WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- After nearly a decade of decline, the preterm birth rate in the United States has risen for the second year in a row, the March of Dimes reports. And racial and ethnic disparities are driving the increase, the group added. The premature birth rate rose from 9.63 percent in 2015 to 9.8 percent in 2016, and the number of preterm births increased by 8,000, according to the group's new report. The premature birth rate was 9.57 percent in 2014, according to the March of Dimes. "The U.S. preterm birth rate is among the worst of highly developed nations," said Stacey Stewart, president of the March of Dimes. "This report card is a public wake-up call, an urgent call to action on the health of our nation's moms and babies." Compared to white women, black women are 49 percent more likely to deliver preterm. For American Indian/Alaska Native women, the number is 18 percent. "Moms and babies face a higher risk of preterm birth based on race and zip code," Stewart said in a March of Dimes news release. A baby born before 37 weeks of pregnancy is considered premature. A full-term birth is around 40 weeks. Each year, more than 380,000 babies are born preterm in the United States, putting them at increased risk of death before their first birthday, lifelong disabilities and chronic health conditions. Preterm birth is the leading cause of infant death in the United States, the organization says. And preterm birth is associated with more than $26 billion annually in avoidable medical and societal costs, according to the National Academy of Medicine. "We must address the social and environmental factors that impact health," said Dr. Paul Jarris, chief medical officer of the March of Dimes. "Only by improving the broader social context for health will we be able to level the playing field for mothers and babies in every community." SOURCE: March of Dimes, news release, Nov. 1, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Health Disparities Health Statistics Premature Babies Recent Health News learn how to


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medical doctor Taking Four or More Prescription Meds? Consider Scaling Back discount

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outcome (*this news item will not be available after 01/30/2018) By Mary Elizabeth Dallas Wednesday, November 1, 2017 TUESDAY, Oct. 31, 2017 (HealthDay News) -- More than half of Americans regularly take about four prescription medications, increasing the likelihood that mistakes could occur, according to Consumer Reports . People taking multiple prescription medications should visit their doctor for a "medication checkup." By showing their doctor or pharmacist a comprehensive list of every drug they are taking, including vitamins and other dietary supplements, patients can be warned about potentially harmful interactions. They can also find out if any of these medications are no longer necessary, which would save them money. Consumer Reports encourages patients to have this type of medication review at least once a year. "Much medication use is lifesaving, without a doubt. But some drugs can potentially do more harm than good," said Lisa Gill, deputy editor of Consumer Reports . "Our concern is that inappropriate prescribing can lead to unnecessary risk, including trips to the emergency room," she said in a news release from the organization. "We hope to encourage consumers to talk with their health care providers about the meds and supplements they take, so they can ultimately lower their risk," Gill said. Use of prescription drugs has surged over the past 20 years. The U.S. population has increased just 21 percent, but the total number of prescriptions filled by Americans has surged 85 percent -- from 2.4 billion prescriptions in 1997 to 4.5 billion in 2016, Consumer Report said. "There are many root causes, including a 'culture of prescribing.' Perhaps most worrisome is prescribing for pre-disease stages of a condition, such as pre-osteoporosis or pre-diabetes, where the medications offer limited benefit for people," Gill said. "And, we've seen a push to treat common problems like back pain, heartburn and insomnia with medication before trying effective, non-drug measures first," she said. People who are on multiple medications also need to be extra careful about possible interactions. "The risk of adverse events increases exponentially after someone is on four or more medications," said Dr. Michael Hochman, of the University of Southern California Keck School of Medicine. The harmful effect of inappropriate prescription drugs sent 1.3 million people to emergency rooms across the United States in 2014. Of these patients, roughly 124,000 died, according to the U.S. Centers for Disease Control and Prevention and the U.S. Food and Drug Administration. Many of these medication events were preventable. Consumer Reports advises that people consider the following questions to determine if they need to have their medications reviewed: How many different doctors prescribed your medication? When multiple doctors prescribe drugs, the risk for harmful interactions rises. Do you take over-the-counter drugs, vitamins or other dietary supplements? Even products that don't require a prescription can pose risks. Do you take more than one medication for the same health issue? This could be a sign that you're taking a drug unnecessarily. Do you need a drug to control the side effects of another medication? This is sometimes necessary but it can also be a warning sign of trouble. Have you been taking your medication for more than three months? Some drugs must be taken long-term, but some can be stopped after a certain length of time. Are you struggling to pay for your medications? There may be other less expensive drugs that are just as effective. SOURCE: Consumer Reports , news release, Oct. 6, 2017 HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Drug Reactions Drug Safety Medicines Recent Health News to admit


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twine (*this news item will not be available after 01/30/2018) Wednesday, November 1, 2017 WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- Babies born with a previously untreatable degenerative nerve disease now have two fresh sources of hope for their future. Two innovative new therapies for spinal muscular atrophy (SMA) type 1 have proven highly effective in clinical trials, researchers report. Babies with SMA are born without the gene that promotes production of survival motor neuron (SMN) protein. Without this protein, nerve cells in the spinal cord and brain stem stop working and start to die off. These babies slowly lose the ability to move their arms and legs. Those with the most severe form, SMA type 1, eventually lose the ability to breathe on their own and rarely survive beyond 2 years of age. Two research groups say they've produced breakthrough therapies for these children. First, a new genetic treatment employed a DNA-loaded virus to replace the missing SMN1 gene with a fresh, healthy copy of the gene. Second, an already-approved drug called nusinersen (Spinraza) was used to promote production of the crucial nerve protein by a backup gene called SMN2. Both approaches increased survival in babies with SMA and preserved or improved their motor function, the researchers said. "These are the first realistic treatment options for SMA," said Dr. Ans van der Ploeg. She is chair of the Center for Lysosomal and Metabolic Diseases at Erasmus MC University in Rotterdam, the Netherlands. Both therapies aim to increase production of SMN protein in the motor neurons and thereby improve the survival and function of motor neurons, she said. This leads to better muscle and respiratory function and survival, added van der Ploeg, who wrote an editorial accompanying the two clinical trial reports. About one in every 11,000 babies is born with SMA, and six in 10 of them have type 1, said Dr. Richard Finkel. He is chief of neurology at Nemours Children's Hospital in Orlando, Fla., and lead researcher of the nusinersen clinical trial. The gene therapy treatment was tested in 15 babies with SMA type 1. All received one intravenous dose of a genetically engineered virus containing the new copy of the SMN gene. The virus is named AVXS-101. This was a phase 1 trial to test safety. "We are trying to replace SMN1 with enough gene that works in enough nerve cells to change function," said lead researcher Dr. Jerry Mendell, director of neuromuscular disorders and neurosciences at Nationwide Children's Hospital in Columbus, Ohio. All 15 patients treated with AVXS-101 are still alive, Mendell said, and some are thriving. Higher doses produced better responses. "All the patients in the trial have improved with the exception of one," Mendell said. "We have patients living out past three years now. And we had patients who actually could walk and run and play." Nusinersen was tested in 80 babies at 31 hospitals as part of a phase III trial prior to its 2016 approval. "The drug is kind of novel," Finkel said. "It's not your standard off-the-shelf pharmacy kind of drug. It's similar to a little piece of DNA." The drug targets the SMN2 gene, a backup gene to the SMN1 gene missing in these babies. It is injected into the spinal fluid. Patients undergo four "loading doses" via lumbar punctures within the first two months, and receive maintenance doses every four months, Finkel said. Nusinersen amps up protein production by the SMN2 gene, potentially halting progression of nerve damage. In the trial, 41 percent of infants who received the earliest treatment with nusinersen and 51 percent of infants in the final analysis experienced stable or improved motor function, the researchers reported. Babies treated with nusinersen also were more likely to survive. The risk of death was 63 percent lower in the nusinersen group compared with the control group, the findings showed. Results were so promising that the clinical trial was halted early so the control group could receive nusinersen, the study authors said. "This study shows the drug has a clinically meaningful response with a higher likelihood of improved survival and motor function," Finkel said. Nusinersen, made by Biogen, is available for treatment now. AVXS-101 will proceed to broader clinical trials involving more children at multiple hospitals, Mendell said. Neither treatment had any clinically significant side effects, according to the researchers. The treatments do not constitute a full cure for children who have already developed symptoms of SMA. However, both research teams hope that kids treated before symptoms arise won't suffer any degenerative nerve loss. Finkel said, "If we can get these babies before they show these signs of weakness, I think that's going to give the best chance for the most robust response, possibly even a cure." Van der Ploeg added that younger, less severely affected patients had a better chance of a good response in the trials. Also, while the gene therapy pilot trial results are promising, more data are required, she noted. The nusinersen trial was paid for by Biogen and the drug's developer, Ionis Pharmaceuticals. The AVXS-101 trial received funding from AveXis, developer of the designer virus. Results of the studies were published in the Nov. 2 issue of the New England Journal of Medicine . SOURCES: Ans van der Ploeg, M.D., Ph.D., chair, Center for Lysosomal and Metabolic Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Richard Finkel, M.D., chief, neurology, Nemours Children's Hospital, Orlando, Fla.; Jerry Mendell, M.D., director, neuromuscular disorders and neurosciences, Nationwide Children's Hospital, Columbus, Ohio; Nov. 2, 2017, New England Journal of Medicine HealthDay Copyright (c) 2017 HealthDay . All rights reserved. News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services. More Health News on Genes and Gene Therapy Recent Health News the child


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for you to SINUTAB Sinus Allergy Medication, Maximum Strength Formula, Caplets (Pfizer Consumer Healthcare) Drug Facts: Active Ingredients: (in each caplet) + Purposes: Acetaminophen 500 mg ............................ Pain reliever Chlorpheniramine maleate 2 mg ....................................................... Antihistamine Pseudoephedrine HCl 30 mg ............................................. Nasal decongestant + Dissolution differs from USP specification Uses: Temporarily relieves these symptoms of hay fever or other upper respiratory allergies: runny nose sneezing itchy, watery eyes itching of the nose or throat headache minor aches and pains nasal congestion Warnings: Alcohol warning: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take acetaminophen or other pain relievers/fever reducers. Acetaminophen may cause liver damage. Do not use: with another product containing any of these active ingredients if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have: glaucoma high blood pressure heart disease thyroid disease diabetes trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product: do not use more than directed drowsiness may occur excitability may occur, especially in children avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery Stop use and ask a doctor if: you get nervous, dizzy, or sleepless new symptoms occur symptoms do not get better you need to use more than 10 days fever occurs and lasts more than 3 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: Taking more than the recommended dose may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. Directions: do not use more than directed (see overdose warning) adults and children 12 years of age and over: 2 caplets children under 12 years of age: ask a doctor take every 6 hours while symptoms persist do not take more than 8 caplets in 24 hours or as directed by a doctor Other Information: store at 59 to 77 F in a dry place Inactive Ingredients: Calcium stearate, candelilla wax, croscarmellose sodium, crospovidone, D&C yellow no. 10 aluminum lake, FD&C yellow no. 6 aluminum lake, hypromellose, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, stearic acid, and titanium dioxide Questions? call 1-800-223-0182, Monday to Friday, 9 AM - 5 PM EST How Supplied Sinutab Sinus Allergy Medication, Maximum Strength Formula Caplets are supplied in child-resistant blister packs in boxes of 24 tablets or caplets. PRODUCT PHOTO(S): NOTE: These photos can be used only for identification by shape, color, and imprint. They do not depict actual or relative size. The product samples shown here have been supplied by the manufacturer. While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases of poisoning or suspected overdosage, the drug's identity should be verified by chemical analysis. Print this page is well known


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Sinutab Non-Drying Generic Name: Guaifenesin and Pseudoephedrine Capsules and Tablets (gwye FEN ah sin & sue do eh FED rin) Brand Name: Robitussin Severe Congestion, Sinutab Non-Drying Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A Uses of Sinutab Non-Drying: It is used to treat nose stuffiness. It is used to thin mucus so it can be taken from the body by coughing. Slideshow Seasoned Pro: Be Mindful of These Winter Health Hazards What do I need to tell my doctor BEFORE I take Sinutab Non-Drying? If you have an allergy to guaifenesin, pseudoephedrine, or any other part of Sinutab Non-Drying (guaifenesin and pseudoephedrine capsules and tablets). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking this medicine within 14 days of those drugs can cause very bad high blood pressure. If you have a cough with a lot of mucous. If you have a long-term cough caused by smoking or being around smoke, or lung problems like asthma or emphysema. This is not a list of all drugs or health problems that interact with Sinutab Non-Drying. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Sinutab Non-Drying? Tell all of your health care providers that you take Sinutab Non-Drying. This includes your doctors, nurses, pharmacists, and dentists. Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects. Do not take this medicine for longer than you were told by your doctor. Avoid driving and doing other tasks or actions that call for you to be alert until you see how Sinutab Non-Drying affects you. Avoid drinking alcohol while taking this medicine. Talk with your doctor before you use other drugs and natural products that slow your actions. Use with care in children. Talk with the doctor. Different brands of Sinutab Non-Drying may be for use in different ages of children. Talk with the doctor before giving this medicine to a child. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Sinutab Non-Drying while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Sinutab Non-Drying) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. Take with food if it causes an upset stomach. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor. What do I do if I miss a dose? If you take Sinutab Non-Drying on a regular basis, take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Many times this medicine is taken on an as needed basis. Do not take more often than told by the doctor. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. What are some other side effects of Sinutab Non-Drying? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dizziness. Feeling nervous and excitable. Not able to sleep. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Sinutab Non-Drying? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Sinutab Non-Drying (guaifenesin and pseudoephedrine capsules and tablets), please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Sinutab Non-Drying. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Sinutab Non-Drying. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Sinutab Non Drying (guaifenesin / pseudoephedrine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: upper respiratory combinations Consumer resources Sinutab Non Drying Other brands: Mucinex D , Pseudovent , Robitussin Severe Congestion , Entex PSE , ... +10 more Professional resources Related treatment guides Cough and Nasal Congestion Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug WADA Class Anti-Doping Classification Sinutab Non Drying Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Drug Class Upper respiratory combinations Related Drugs Cough and Nasal Congestion Promethazine VC with Codeine , Bromfed DM , Mucinex D , Vanacof , Deconex , codeine / phenylephrine / promethazine , Resperal-DM , Vicks NyQuil Severe Cold & Flu , Vicks Nyquil Cough , Coricidin HBP Cough & Cold , Deconex DMX , Crantex , Tussin CF , Robitussin Allergy & Cough , Robitussin Nighttime Cough DM , Relasin-HC , Mucinex Fast-Max Severe Congestion & Cough , Dimetapp Children's Cold & Cough , More... surgical treatment


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honestly Sinutab Non Drying Generic Name: guaifenesin and pseudoephedrine (gwye FEN e sin, SOO doe ee FED rin) Brand Name: Ambifed-G, Despec-SR, Entex T, Maxifed, Mucinex D, Mucinex D Max Strength, Poly-Vent IR, Respaire-30, Robitussin Severe Congestion, Sinutab Non Drying, Triaminic Softchews Chest Congestion, Tusnel Pediatric Drops Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A What is Sinutab Non Drying (guaifenesin and pseudoephedrine)? There are many brands and forms of guaifenesin and pseudoephedrine available and not all brands are listed on this leaflet. Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth. Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Guaifenesin and pseudoephedrine is a combination medicine used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu. Guaifenesin and pseudoephedrine may also be used for purposes not listed in this medication guide. Slideshow OTC Medication Use In Pregnancy: Wise or Worrisome? What is the most important information I should know about Sinutab Non Drying (guaifenesin and pseudoephedrine)? Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. What should I discuss with my healthcare provider before taking Sinutab Non Drying (guaifenesin and pseudoephedrine)? You should not use guaifenesin and pseudoephedrine if you are allergic to it. Do not use guaifenesin and pseudoephedrine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Ask a doctor or pharmacist if it is safe for you to take this medication if you have: high blood pressure, heart disease, coronary artery disease; diabetes; circulation problems; glaucoma; overactive thyroid; or enlarged prostate or problems with urination. It is not known if this medication may be harmful to an unborn baby. Do not use this medicine without medical advice if you are pregnant. Guaifenesin and pseudoephedrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without medical advice if you are breast-feeding a baby. Artificially sweetened liquid medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU). How should I take Sinutab Non Drying (guaifenesin and pseudoephedrine)? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. The chewable tablet must be chewed before you swallow it. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. Store at room temperature away from moisture and heat. What happens if I miss a dose? Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking Sinutab Non Drying (guaifenesin and pseudoephedrine)? This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol with this medicine can cause side effects. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and pseudoephedrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Sinutab Non Drying (guaifenesin and pseudoephedrine) side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using guaifenesin and pseudoephedrine and call your doctor at once if you have: fast, pounding, or uneven heartbeat; or severe anxiety or nervousness. Common side effects may include: dry mouth, nose, or throat; upset stomach, loss of appetite, vomiting; feeling excited or restless (especially in children); sleep problems (insomnia); or headache, dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) What other drugs will affect Sinutab Non Drying (guaifenesin and pseudoephedrine)? Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide. Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking guaifenesin and pseudoephedrine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Next Side Effects Print this page Add to My Med List More about Sinutab Non Drying (guaifenesin / pseudoephedrine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: upper respiratory combinations Consumer resources Sinutab Non-Drying Other brands: Mucinex D , Pseudovent , Robitussin Severe Congestion , Entex PSE , ... +10 more Professional resources Related treatment guides Cough and Nasal Congestion Where can I get more information? Your pharmacist can provide more information about guaifenesin and pseudoephedrine. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 11.06. Date modified: December 03, 2017 Last reviewed: May 03, 2017} Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug WADA Class Anti-Doping Classification Drug Class Upper respiratory combinations Related Drugs Cough and Nasal Congestion Promethazine VC with Codeine , Bromfed DM , Mucinex D , Vanacof , Deconex , codeine / phenylephrine / promethazine , Vicks NyQuil Severe Cold & Flu , Resperal-DM , Vicks Nyquil Cough , Coricidin HBP Cough & Cold , Deconex DMX , Crantex , Tussin CF , Robitussin Allergy & Cough , Robitussin Nighttime Cough DM , Dimetapp Children's Cold & Cough , Mucinex Fast-Max Severe Congestion & Cough , Relasin-HC , More... Sinutab Non Drying Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the Sinutab Non Drying support group to connect with others who have similar interests.} } of ethical


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