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simplest way [6:2% are provided in Table 6. The most frequent adverse reactions were hypotension, bradycardia, and dry mouth [ see Warnings and Precautions (5.2) ]. Pre-specified criteria for the vital signs to be reported as adverse reactions are footnoted below the table. The decrease in respiratory rate and hypoxia was similar between dexmedetomidine hydrochloride and comparator groups in both studies. Table 6: Adverse Reactions With an Incidence > 2% Procedural Sedation Population Adverse Event Dexmedetomidine Hydrochloride N = 318 (%) Placebo N = 113 (%) Hypotension 1 54% 30% Respiratory depression 2 37% 32% Bradycardia 3 14% 4% Hypertension 4 13% 24% Tachycardia 5 5% 17% Nausea 3% 2% Dry mouth 3% 1% Hypoxia 6 2% 3% Bradypnea 2% 4% 1 Hypotension was defined in absolute and relative terms as Systolic blood pressure of] FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Akorn, Inc. Mylan Pharmaceuticals Inc. Sandoz Inc. Teva Pharmaceuticals USA, Inc. Sun Pharmaceutical Industries Inc. Fresenius Kabi USA, LLC More... Drug Class Miscellaneous anxiolytics, sedatives and hypnotics Related Drugs miscellaneous anxiolytics, sedatives and hypnotics zolpidem , Ambien , hydroxyzine , melatonin , buspirone , diphenhydramine Sedation trazodone , promethazine , lorazepam , hydroxyzine , Ativan , fentanyl , Vistaril , Phenergan , phenobarbital , Atarax , Desyrel , butabarbital , Precedex , Luminal , Promethegan , Talwin , dexmedetomidine , pentazocine , Sublimaze , Nembutal , pentobarbital , chloral hydrate , Seconal , amobarbital , More... Dexmedetomidine Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! suits


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