a method Eserine (Ophthalmic) Generic Name: physostigmine (Ophthalmic route) fye-soe-STIG-meen Overview Side Effects Interactions Breastfeeding Reviews More Commonly used brand name(s) In the U.S. Eserine Isopto Eserine Available Dosage Forms: Solution Ointment Therapeutic Class: Antiglaucoma Pharmacologic Class: Cholinesterase Inhibitor Slideshow Aging Eyes - 8 Common Vision Problems Associated with Aging Uses For Eserine Physostigmine is used to treat certain types of glaucoma. This medicine is available only with your doctor's prescription. Before Using Eserine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Although there is no specific information comparing use of this medicine in children with use in other age groups, it is not expected to cause different side effects or problems in children than it does in adults. Geriatric Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Although there is no specific information comparing use of physostigmine in the elderly with use in other age groups, it is not expected to cause different side effects or problems in older people than it does in younger adults. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Bupropion Donepezil Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Succinylcholine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Eye disease or problems (other) Physostigmine may make the condition worse Proper Use of physostigmine This section provides information on the proper use of a number of products that contain physostigmine. It may not be specific to Eserine. Please read with care. To use the ophthalmic solution (eye drops) form of this medicine: Do not use if the solution becomes discolored. First, wash your hands. With the middle finger, apply pressure to the inside corner of the eye (and continue to apply pressure for 1 or 2 minutes after the medicine has been placed in the eye). Tilt the head back and with the index finger of the same hand, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed. Immediately after using the eye drops, wash your hands to remove any medicine that may be on them. To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. To use the ointment form of this medicine: First, wash your hands. Pull the lower eyelid away from the eye to form a pouch. Squeeze a thin strip of ointment into the pouch. A 1-cm (approximately 1/3-inch) strip of ointment is usually enough unless otherwise directed by your doctor. Gently close the eyes and keep them closed for 1 or 2 minutes to allow the medicine to be absorbed. Immediately after using the eye ointment, wash your hands to remove any medicine that may be on them. To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using the eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed. Use this medicine only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For glaucoma: For ophthalmic ointment dosage form: Adults and children Use in each eye one to three times a day. For ophthalmic solution (eye drops) dosage form: Adults and children One drop in each eye up to four times a day. Missed Dose If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Precautions While Using Eserine Your doctor should check your eye pressure at regular visits. For a short time after you apply this medicine, your vision may be blurred or there may be a change in your near or distant vision, especially at night. Make sure your vision is clear before you drive, use machines, or do anything else that could be dangerous if you are not able to see well . Eserine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur: Symptoms of too much medicine being absorbed into the body Increased sweating loss of bladder control muscle weakness nausea, vomiting, diarrhea, or stomach cramps or pain shortness of breath, tightness in chest, or wheezing slow or irregular heartbeat unusual tiredness or weakness watering of mouth Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Blurred vision or change in near or distant vision eye pain Less common Burning, redness, stinging, or other eye irritation headache or browache twitching of eyelids watering of eyes Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Eserine Sulfate Ophthalmic (physostigmine ophthalmic) Side Effects Breastfeeding Drug Interactions 0 Reviews Add your own review/rating Drug class: ophthalmic glaucoma agents Related treatment guides Glaucoma} Drug Status Availability Discontinued C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Ophthalmic glaucoma agents Related Drugs Glaucoma Combigan , nadolol , pilocarpine ophthalmic , acetazolamide , Diamox , mitomycin ophthalmic , Corgard , methazolamide , physostigmine ophthalmic , carbachol ophthalmic , Diamox Sequels , Iopidine , Isopto Carpine , Neptazane , Mitosol , Miostat , Pilopine HS , Isopto Carbachol , apraclonidine ophthalmic , Phospholine Iodide , More... 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