condominium Dilaudid-HP (Injection) Generic Name: hydromorphone (Injection route) hye-droe-MOR-fone hye-droe-KLOR-ide Injection route(Powder for Solution;Solution) Dilaudid-HP(R) and Dilaudid(R) (HYDROmorphone hydrochloride injection high potency formulation (HPF)) are highly concentrated solutions of HYDROmorphone that are intended for use only in opioid-tolerant patients. Do not confuse Dilaudid-HP(R) or Dilaudid (R) (HYDROmorphone hydrochloride injection high potency formulation (HPF)) with standard parenteral formulations of HYDROmorphone or other opioids, as overdose and death could result. HYDROmorphone hydrochloride exposes users to risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk before prescribing, and monitor regularly for development of these behaviors or conditions. Serious, life-threatening, or fatal respiratory depression may occur. Monitor closely, especially upon initiation or following a dose increase. Prolonged use of HYDROmorphone hydrochloride during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available. Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Dilaudid Dilaudid-HP Available Dosage Forms: Solution Powder for Solution Therapeutic Class: Analgesic Chemical Class: Hydromorphone Slideshow Top 11 Truths About Narcotic Painkiller Meds Uses For Dilaudid-HP Hydromorphone injection is used to treat moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines) and acts on the central nervous system (CNS) to relieve pain. Do not use this medicine for mild pain or pain that you only have once in a while or "as needed." When hydromorphone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve the pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. Severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time. This medicine is available only with your doctor's prescription. Before Using Dilaudid-HP In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of hydromorphone injection in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydromorphone injection in the elderly. However, elderly patients are more likely to have age-related lung, kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving hydromorphone injection in order to avoid serious side effects. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Nalmefene Naltrexone Safinamide Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acepromazine Alfentanil Almotriptan Alprazolam Amineptine Amisulpride Amitriptyline Amitriptylinoxide Amobarbital Amoxapine Amphetamine Anileridine Aripiprazole Asenapine Baclofen Benperidol Benzphetamine Bromopride Brompheniramine Buprenorphine Buspirone Butabarbital Butorphanol Carbamazepine Carbinoxamine Carisoprodol Carphenazine Chloral Hydrate Chlordiazepoxide Chlorpheniramine Chlorpromazine Chlorzoxazone Citalopram Clobazam Clomipramine Clonazepam Clorazepate Clozapine Cocaine Codeine Cyclobenzaprine Desipramine Desmopressin Desvenlafaxine Dexmedetomidine Dextroamphetamine Dextromethorphan Dezocine Diazepam Dibenzepin Dichloralphenazone Difenoxin Dihydrocodeine Diphenhydramine Diphenoxylate Dolasetron Donepezil Doxepin Doxylamine Droperidol Duloxetine Eletriptan Enflurane Escitalopram Estazolam Eszopiclone Ethchlorvynol Ethopropazine Ethylmorphine Fentanyl Flibanserin Fluoxetine Fluphenazine Flurazepam Fluspirilene Fluvoxamine Fospropofol Frovatriptan Furazolidone Granisetron Halazepam Haloperidol Halothane Hexobarbital Hydrocodone Hydroxytryptophan Hydroxyzine Imipramine Iproniazid Isocarboxazid Isoflurane Ketamine Ketazolam Ketobemidone Levomilnacipran Levorphanol Linezolid Lisdexamfetamine Lithium Lofepramine Lorazepam Lorcaserin Loxapine Meclizine Melitracen Melperone Meperidine Mephobarbital Meprobamate Meptazinol Mesoridazine Metaxalone Methadone Methamphetamine Methdilazine Methocarbamol Methohexital Methotrimeprazine Methylene Blue Midazolam Milnacipran Mirtazapine Moclobemide Molindone Moricizine Morphine Morphine Sulfate Liposome Nalbuphine Naratriptan Nefazodone Nialamide Nicomorphine Nitrazepam Nitrous Oxide Nortriptyline Olanzapine Ondansetron Opipramol Opium Opium Alkaloids Orphenadrine Oxazepam Oxycodone Oxymorphone Palonosetron Papaveretum Paregoric Paroxetine Pentazocine Pentobarbital Perampanel Perazine Periciazine Perphenazine Phenelzine Phenobarbital Pimozide Piperacetazine Pipotiazine Piritramide Prazepam Primidone Procarbazine Prochlorperazine Promazine Promethazine Propofol Protriptyline Quazepam Quetiapine Ramelteon Rasagiline Remifentanil Remoxipride Rizatriptan Secobarbital Selegiline Sertindole Sertraline Sibutramine Sodium Oxybate St John's Wort Sufentanil Sulpiride Sumatriptan Suvorexant Tapentadol Temazepam Thiethylperazine Thiopental Thiopropazate Thioridazine Tianeptine Tilidine Tizanidine Tolonium Chloride Topiramate Tramadol Tranylcypromine Trazodone Triazolam Trifluoperazine Trifluperidol Triflupromazine Trimeprazine Trimipramine Tryptophan Venlafaxine Vilazodone Vortioxetine Zaleplon Ziprasidone Zolmitriptan Zolpidem Zopiclone Zotepine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Addison disease (adrenal gland problem) or Alcohol abuse, acute or Breathing or lung problems, severe (eg, asthma, apnea, low oxygen levels) or Chronic obstructive pulmonary disease (COPD) or Cor pulmonale (serious heart condition) or Depression, history of or Drug dependence, especially narcotic abuse or dependence, or history of or Gallbladder disease or gallstones or Head injury, history of or Hypothyroidism (an underactive thyroid) or Kyphoscoliosis (curvature of the spine with breathing problems) or Mental health problems, history of or Problems with passing urine or Prostatic hypertrophy (enlarged prostate, BPH) Use with caution. May increase risk for more serious side effects. Allergy to sulfites or Stomach or bowel blockage (eg, paralytic ileus) Should not be used in patients with these conditions. Hypotension (low blood pressure) or Pancreatitis (inflammation of the pancreas) or Seizures, history of Use with caution. May make these conditions worse. Kidney disease or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Patients who are not opioid-tolerant Dilaudid-HP should not be given in these patients. Proper Use of hydromorphone This section provides information on the proper use of a number of products that contain hydromorphone. It may not be specific to Dilaudid-HP. Please read with care. A nurse or other trained health professional will give you this medicine in a hospital. This medicine may be given as a shot under the skin, as a shot into one of your muscles, or through a needle placed in one of your veins. Hydromorphone injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using this medicine at home, your doctor will teach you how to prepare and inject the medicine. Be sure you understand the instructions before giving yourself an injection. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Use a new needle and syringe each time you inject the medicine. If the medicine in the vial has changed color, or if you see particles in it, do not use it. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For injection (intramuscular or subcutaneous) dosage forms: For moderate to severe pain: For patients who are not taking opioid medicines (not opioid-tolerant): Adults At first, 1 to 2 milligrams (mg) injected under the skin or into one of your muscles every 2 to 3 hours as needed. Your doctor may adjust your dose as needed. Children Use and dose must be determined by your doctor. For patients who are already taking opioid medicines (opioid-tolerant): Adults Your dose is based on the narcotic pain medicine you are already receiving. Your doctor may adjust your dose as needed. Children Use and dose must be determined by your doctor. Missed Dose Call your doctor or pharmacist for instructions. Storage Keep out of the reach of children. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Dilaudid-HP It is very important that your doctor check your progress while you are receiving this medicine . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. This effect may last for a few days after you stop using this medicine. Check with your doctor before drinking alcohol or taking any of the medicines listed above while you are using this medicine . This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. This medicine may make you dizzy, drowsy, confused, or disoriented. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are receiving this medicine. If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without checking with your doctor . Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping. Some babies who are born to mothers physically dependent on this medicine will also be physically dependent and may have breathing problems and withdrawal symptoms. This could be life-threatening and requires immediate medical attention. Check with your doctor right away if your baby has difficulty with breathing, shortness of breath, excessive crying, irritability, fever, vomiting, or tremors. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Using too much of this medicine may cause reduced infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Dilaudid-HP Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: Incidence not known Abdominal or stomach pain blurred vision change in consciousness change in the ability to see colors, especially blue or yellow chest pain or discomfort cold, clammy skin confusion cough difficult or troubled breathing dizziness fast, pounding, or irregular heartbeat or pulse headache irregular, fast, slow, or shallow breathing lightheadedness, dizziness, or fainting loss of appetite noisy breathing pale or blue lips, fingernails, or skin severe constipation severe vomiting slow or irregular heartbeat sweating tightness in the chest trouble with sleeping unusual tiredness very slow heartbeat or pulse vomiting Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Change in consciousness cold and clammy skin convulsions (seizures) drowsiness that is so severe you are not able to answer when spoken to or, if asleep, cannot be awakened pale or blue lips, fingernails, or skin pinpoint (small) pupils in the eyes sleepiness or unusual drowsiness slow heartbeat unable to speak very slow or troubled breathing weak muscle tone Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Incidence not known Anxiety bad, unusual, or unpleasant (after) taste burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings change in taste chills constricted, pinpoint, or small pupils (black part of the eye) decrease in the frequency or amount of urination diarrhea difficulty having a bowel movement (stool) difficulty in passing urine (dribbling) double vision dry mouth false or unusual sense of well-being fast or rapid breathing feeling of warmth hives or welts irritability itching loss of appetite muscle stiffness or tightness nausea painful urination redness, pain, or swelling at the injection site redness of the face, neck, arms, and occasionally, upper chest relaxed or calm feeling seeing, hearing, or feeling things that are not there seeing double shaking sleepiness uncontrolled eye movements upper stomach pain weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about Dilaudid-HP (hydromorphone) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 8 Reviews Add your own review/rating Generic Availability Drug class: narcotic analgesics Consumer resources Dilaudid-HP injection Other brands: Exalgo , Palladone Professional resources Dilaudid-HP (FDA) Hydromorphone Hydrochloride (AHFS Monograph) Other Formulations Dilaudid Related treatment guides Anesthetic Adjunct Chronic Pain Pain} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out 2 CSA Schedule High potential for abuse Approval History Drug history at FDA WADA Class Anti-Doping Classification Drug Class Narcotic analgesics Related Drugs Chronic Pain tramadol , oxycodone , Cymbalta , duloxetine , Percocet , morphine , fentanyl , More... Pain tramadol , acetaminophen , Tylenol , naproxen , oxycodone , aspirin , ibuprofen , More... Anesthetic Adjunct fentanyl , hydromorphone , butorphanol , Stadol , Sublimaze , atracurium , methohexital , thiopental , More... Dilaudid-HP Rating 8 User Reviews 7.8 /10 8 User Reviews 7.8 Rate it! Related Questions & Answers Hydromorphone - do dilaudid 8mg come in the color yellow? Read more questions} } the goods
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