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fighting [1%:1.5 mg/dL. Fourteen patients who received Sevoflurane were compared with 12 patients who received isoflurane. In another study, 21 patients who received Sevoflurane were compared with 20 patients who received enflurane. Creatinine levels increased in 7% of patients who received Sevoflurane, 8% of patients who received isoflurane, and 10% of patients who received enflurane. Because of the small number of patients with renal insufficiency (baseline serum creatinine greater than 1.5 mg/dL) studied, the safety of Sevoflurane administration in this group has not yet been fully established. Therefore, Sevoflurane should be used with caution in patients with renal insufficiency (see WARNINGS ). Indications and Usage for Sevoflurane Sevoflurane is indicated for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery. Sevoflurane should be administered only by persons trained in the administration of general anesthesia. Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. Since level of anesthesia may be altered rapidly, only vaporizers producing predictable concentrations of Sevoflurane should be used. Contraindications Sevoflurane can cause malignant hyperthermia. It should not be used in patients with known sensitivity to Sevoflurane or to other halogenated agents nor in patients with known or suspected susceptibility to malignant hyperthermia. Warnings Although data from controlled clinical studies at low flow rates are limited, findings from patient and animal studies suggest that there is a potential for renal injury which is presumed due to Compound A. Animal and human studies demonstrate that Sevoflurane administered for more than 2 MAC hours and at fresh gas flow rates of] FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Baxter International Inc. Sandoz Inc. Piramal Healthcare Drug Class General anesthetics Related Drugs general anesthetics propofol , ketamine , etomidate , Diprivan , methohexital , Ketalar Anesthesia lidocaine , fentanyl , hyoscyamine , propofol , Levsin , ketamine , glycopyrrolate , Emla , Robinul , butorphanol , etomidate , succinylcholine , Nubain , Diprivan , benzocaine topical , Stadol , Levbid , rocuronium , Talwin , pentazocine , Sublimaze , nalbuphine , Anaspaz , HyoMax , cisatracurium , More... Sevoflurane Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! undoubtedly


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