lack of awareness Se-Donna PB Hyos (Oral) Generic Name: belladonna alkaloids and phenobarbital (Oral route) AT-roe-peen SUL-fate, hye-oh-SYE-a-meen SUL-fate, fee-noe-BAR-bi-tal, skoe-POL-a-meen hye-droe-BROE-mide Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Commonly used brand name(s) In the U.S. Antispasmodic Belladonna/Phenobarbital Donnatal RE-PB Hyos Se-Donna PB Hyos Available Dosage Forms: Elixir Tablet, Extended Release Liquid Capsule Tablet Therapeutic Class: Antimuscarinic Combination Pharmacologic Class: Atropine Slideshow Bowled Over By Your Bowel: IBS Causes, Risk Factors and Treatments Uses For Se-Donna PB Hyos Belladonna alkaloids and phenobarbital combination is used to treat cramping and spasms in the stomach and intestines. It may also be used for stomach ulcers. This medicine is available only with your doctor's prescription. Before Using Se-Donna PB Hyos In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Severe side effects may be more likely to occur in infants and children, especially those with spastic paralysis or brain damage. Unusual excitement, nervousness, restlessness, or irritability and unusual warmth, dryness, and flushing of skin are more likely to occur in children, who are usually more sensitive to the effects of belladonna alkaloids. Also, when belladonna alkaloids are given to children during hot weather, a rapid increase in body temperature may occur. In addition, the barbiturate in this medicine could cause some children to become hyperactive. Geriatric Confusion or memory loss; constipation; difficult urination; drowsiness; dryness of mouth, nose, throat, or skin; and unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in the elderly, who are usually more sensitive than younger adults to the effects of belladonna alkaloids and barbiturates. Also, eye pain may occur, which may be a sign of glaucoma. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Ambenonium Atazanavir Boceprevir Cobicistat Darunavir Dasabuvir Elvitegravir Ombitasvir Paritaprevir Potassium Ranolazine Rilpivirine Ritonavir Telaprevir Voriconazole Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acenocoumarol Alfentanil Alprazolam Amobarbital Anisindione Aprobarbital Axitinib Bosutinib Bromazepam Bromopride Buprenorphine Bupropion Butabarbital Butalbital Butorphanol Calcifediol Carbinoxamine Carisoprodol Carmustine Chloral Hydrate Chlordiazepoxide Chlorzoxazone Clarithromycin Clobazam Clonazepam Clorazepate Clozapine Cobimetinib Codeine Daclatasvir Dantrolene Deferasirox Deflazacort Delavirdine Diazepam Dicumarol Dihydrocodeine Donepezil Doxorubicin Doxorubicin Hydrochloride Liposome Doxylamine Dronedarone Elbasvir Erlotinib Eslicarbazepine Acetate Estazolam Ethchlorvynol Etonogestrel Etravirine Fentanyl Fluconazole Flunitrazepam Flurazepam Grazoprevir Halazepam Hydrocodone Hydromorphone Ifosfamide Imatinib Ketazolam Ledipasvir Levorphanol Lopinavir Lorazepam Lormetazepam Meclizine Medazepam Meperidine Mephenesin Mephobarbital Meprobamate Metaxalone Methadone Methocarbamol Methohexital Methoxyflurane Midazolam Mifepristone Morphine Morphine Sulfate Liposome Nalbuphine Nifedipine Nimodipine Nitrazepam Olaparib Orlistat Oxazepam Oxycodone Oxymorphone Pentazocine Pentobarbital Periciazine Phenindione Phenobarbital Phenprocoumon Piperaquine Prazepam Primidone Quazepam Remifentanil Saquinavir Secobarbital Simeprevir Sirolimus Sodium Oxybate Sonidegib Sufentanil Sunitinib Tacrolimus Tapentadol Temazepam Teniposide Tenofovir Alafenamide Thiopental Tiotropium Tolvaptan Tramadol Triazolam Ulipristal Velpatasvir Venetoclax Zolpidem Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Amprenavir Arbutamine Betamethasone Bexarotene Cannabis Carbamazepine Chlorpromazine Cortisone Dexamethasone Digitoxin Ethosuximide Felodipine Ginkgo Granisetron Griseofulvin Lamotrigine Leucovorin Levomethadyl Methylprednisolone Metoprolol Ospemifene Oxcarbazepine Prednisone Quinidine Quinine Risperidone Rufinamide Telithromycin Theophylline Thioridazine Tiagabine Topiramate Valproic Acid Verapamil Warfarin Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Asthma or Dry mouth or Emphysema (type of lung disease) or Enlarged prostate or Glaucoma or Heart disease or Hyperactivity (in children) or Intestinal blockage or Ulcerative colitis or Urinary tract blockage or difficult urination Use with caution. May make these conditions worse. Down's syndrome Use with caution. May make the side effects worse. Kidney disease or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of belladonna alkaloids and phenobarbital This section provides information on the proper use of a number of products that contain belladonna alkaloids and phenobarbital. It may not be specific to Se-Donna PB Hyos. Please read with care. Take this medicine about 30 minutes to 1 hour before meals, unless otherwise directed by your doctor. Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For stomach or intestine problems: For oral dosage forms (capsules or tablets): Older adults, adults, and teenagers 1 or 2 capsules 2 to 4 times a day. Your doctor may adjust the dose if needed. Children Dose must be determined by your doctor. For oral dosage form (solution): Adults and teenagers The usual dose is 1 to 2 teaspoons (5 to 10 milliliters (mL)) 3 or 4 times a day. Your doctor may adjust the dose if needed. Children Dose is based on body weight and must be determined by your doctor. The usual dose is 0.5 to 7.5 mL every 4 to 6 hours. Your doctor may adjust the dose if needed. For oral dosage form (chewable tablets): Older adults, adults, and teenagers Chew 1 or 2 tablets 3 or 4 times a day. Your doctor may adjust the dose if needed. Children 2 to 12 years of age Chew one-half to 1 tablet 3 or 4 times a day. Your doctor may adjust the dose if needed. Children up to 2 years of age Use is not recommended. For long-acting oral dosage form (extended-release tablets): Older adults, adults, and teenagers 1 tablet every 8 to 12 hours. Your doctor may adjust the dose if needed. Children Use is not recommended. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Keep out of the reach of children. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Do not keep outdated medicine or medicine no longer needed. Precautions While Using Se-Donna PB Hyos This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine . Do not take this medicine within 1 hour of taking antacids or medicine for diarrhea. Taking them too close together will make the belladonna alkaloids less effective. Belladonna alkaloids will often make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine , as overheating could possibly result in heat stroke. This is especially important in children taking belladonna alkaloids. This medicine may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort. This medicine may cause some people to have blurred vision or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see well . This medicine may cause a dry mouth, nose, or throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections. Se-Donna PB Hyos Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare Eye pain skin rash or hives sore throat and fever unusual bleeding or bruising yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Constipation decreased sweating dizziness dry mouth, nose, throat, or skin Less common or rare Bloated feeling blurred vision decreased flow of breast milk difficult urination difficulty in swallowing headache increased sensitivity of eyes to sunlight loss of memory nausea or vomiting unusual tiredness or weakness Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Se-Donna PB HYOS (atropine / hyoscyamine / phenobarbital / scopolamine) Side Effects During Pregnancy Dosage Information Drug Interactions 0 Reviews Add your own review/rating Drug class: anticholinergics/antispasmodics Consumer resources Other brands: Donnatal , Antispasmodic , Donnatal Extentabs , Hyosophen , ... +3 more Professional resources Se-Donna Pb Hyos (FDA) Related treatment guides Irritable Bowel Syndrome} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Anticholinergics / antispasmodics Related Drugs Irritable Bowel Syndrome dicyclomine , Amitiza , Bentyl , Metamucil , psyllium , hyoscyamine , Levsin , Librax , lubiprostone , Donnatal , chlordiazepoxide / clidinium , Levbid , Konsyl , Anaspaz , alosetron , HyoMax , Lotronex , Levsin SL , Hyosyne , Antispasmodic , Reguloid , More... 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