a hundred and fortieth Tafinlar Generic Name: Dabrafenib (da BRAF e nib) Brand Name: Tafinlar Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons Uses of Tafinlar: It is used to treat a type of skin cancer (melanoma). Slideshow Looking Ahead: New Drug Approvals for 2017 What do I need to tell my doctor BEFORE I take Tafinlar? If you have an allergy to dabrafenib or any other part of Tafinlar (dabrafenib). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are breast-feeding. Do not breast-feed while you take this medicine and for 2 weeks after your last dose. This medicine may interact with other drugs or health problems. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Tafinlar with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Tafinlar? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Sometimes, dabrafenib is taken with trametinib. If you are taking dabrafenib with trametinib, be sure you know the side effects that can happen with each drug. When these drugs are taken together, the chance of certain side effects may be raised. These side effects can be very bad and sometimes deadly. This includes bleeding, bleeding in the brain, blood clots, eye problems, fever, heart problems (like heart failure), high blood sugar, other cancers, and skin problems. Talk with your doctor about the chance of side effects with your drugs. This medicine may add to the chance of getting some types of cancer. Talk with the doctor. Have your skin checked. Tell your doctor if you have any skin changes like a new wart, skin sore or reddish bump that bleeds or does not heal, or a change in the color or size of a mole. Have blood work checked as you have been told by the doctor. Talk with the doctor. If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar. Check your blood sugar as you have been told by your doctor. It is common to get a rash with Tafinlar but other skin reactions may also happen. Sometimes, these rashes and skin reactions can be very bad and may need treatment in the hospital. Call your doctor right away if you have acne, skin redness, or a skin rash that bothers you or does not go away. Call your doctor right away if you have redness or irritation of the palms of hands or soles of feet. Very bad eye problems have happened with this medicine. Sometimes, this has led to loss of eyesight. Call your doctor right away if you have blurred eyesight, loss of eyesight, or other changes in eyesight. Call your doctor right away if you see color dots or halos or if bright lights bother you. Be careful if you have G6PD deficiency. Anemia may happen. If you are 65 or older, use Tafinlar with care. You could have more side effects. This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. Talk with the doctor. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Use birth control that you can trust to prevent pregnancy while taking this medicine and for at least 2 weeks after stopping the drug. Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking Tafinlar and for 2 weeks after stopping this medicine. If you get pregnant while taking Tafinlar or within 2 weeks after your last dose, call your doctor right away. How is this medicine (Tafinlar) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take on an empty stomach. Take 1 hour before or 2 hours after meals. Swallow whole. Do not chew, open, or crush. Talk with your doctor about drinking lots of fluids and other ways to prevent fluid loss. If you have a lot of fluid loss, you may have more side effects from Tafinlar. To gain the most benefit, do not miss doses. Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well. What do I do if I miss a dose? Take a missed dose as soon as you think about it. If it is less than 6 hours until the next dose, skip the missed dose and go back to the normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop. Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up. Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit. Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Fever or chills. Dark urine or yellow skin or eyes. Eye pain. Chest pain or pressure. Very bad headache. This medicine may cause heart failure. You will need to have your heart function checked while taking Tafinlar (dabrafenib). Call your doctor right away if you have signs of heart problems like a cough or shortness of breath that is new or worse, swelling of the ankles or legs, a heartbeat that does not feel normal, weight gain of more than 5 pounds in 24 hours, dizziness, or passing out. What are some other side effects of Tafinlar? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Hair loss. Change in skin to hard and thick. Headache. Muscle or joint pain. Back pain. Hard stools (constipation). Cough. Nose and throat irritation. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Tafinlar? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine is refilled. If you have any questions about Tafinlar, please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Tafinlar. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Tafinlar. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Tafinlar (dabrafenib) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Español 1 Review Add your own review/rating Drug class: multikinase inhibitors Consumer resources Tafinlar Tafinlar (Advanced Reading) Professional resources Tafinlar (AHFS Monograph) Tafinlar (FDA) Related treatment guides Melanoma, Metastatic} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug 4 years Approval History FDA approved 2013 Tafinlar Rating 1 User Review 9.0 /10 1 User Review 9.0 Rate it! Manufacturer Novartis Pharmaceuticals Corporation Drug Class Multikinase inhibitors Related Drugs Melanoma, Metastatic Opdivo , Keytruda , nivolumab , pembrolizumab , Yervoy , ipilimumab , Mekinist , trametinib , dabrafenib , Proleukin , dacarbazine , Zelboraf , vemurafenib , cobimetinib , Cotellic , PegIntron , Sylatron , aldesleukin , Imlygic , peginterferon alfa-2b , More... Tafinlar Images Tafinlar 50 mg (GS TEW 50 mg) View larger images} } it's important
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