immediately talimogene laherparepvec (Injection route) tal-IM-oh-jeen la-her-pa-REP-vek Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Imlygic Available Dosage Forms: Suspension Therapeutic Class: Antineoplastic Agent Slideshow Looking Ahead: New Drug Approvals for 2017 Uses For talimogene laherparepvec Talimogene laherparepvec injection is used to treat melanoma (skin cancer) when it is on your skin or in your lymph glands. talimogene laherparepvec is a weakened form of Herpes Simplex Virus Type 1 (cold sore virus). talimogene laherparepvec is given only by or under the direct supervision of your doctor. Before Using talimogene laherparepvec In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For talimogene laherparepvec, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to talimogene laherparepvec or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of talimogene laherparepvec injection in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of talimogene laherparepvec injection in the elderly. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of talimogene laherparepvec. Make sure you tell your doctor if you have any other medical problems, especially: Autoimmune disease or Glomerulonephritis (kidney problem) or Pneumonitis (inflammation of the lung tissue) or Psoriasis (skin problem) or Vasculitis (inflammation of the blood vessels) or Vitiligo (skin problem) Use with caution. May make these conditions worse. Leukemia, history of or Lymphoma, history of or Weak immune system (including AIDS or HIV infection), history of Should not be used in patients with these conditions. Multiple myeloma May increase risk for more serious side effects. Proper Use of talimogene laherparepvec A doctor or other trained health professional will give you talimogene laherparepvec in a hospital or cancer treatment center. talimogene laherparepvec is injected directly into your tumor(s). You will receive talimogene laherparepvec again 3 weeks after your first treatment. After that, you will receive talimogene laherparepvec every 2 weeks for as long as you have tumor(s). talimogene laherparepvec should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Precautions While Using talimogene laherparepvec Your doctor will check your progress closely while you are receiving talimogene laherparepvec . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects. Using talimogene laherparepvec while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. talimogene laherparepvec can spread to other areas of the body or to other people (eg, household members, caregiver, or persons sharing the same bed). To avoid spreading the medicine: Avoid direct contact between your treatment sites, dressings, body fluids or close contacts. Do not touch or scratch the treatment sites. Wear gloves when putting on or changing your dressings. Cover the treatment sites with airtight and watertight dressings for at least 1 week after each treatment. If the dressing comes loose or falls off, use a new, clean dressing to replace it. Place all used dressings and cleaning materials in a sealed plastic bag and throw them in the trash can. talimogene laherparepvec may cause herpes infections (including cold sores). Tell your doctor right away if you have pain, burning, or tingling in a blister around the mouth or genitals or on the fingers or ears, confusion, extreme drowsiness, blurred vision, eye pain, sensitivity to light, or weakness in your arms or legs. talimogene laherparepvec may cause delayed healing at the injection site. It is more likely to occur if you had previous radiation treatment at the injection site or lesions. Tell your doctor right away if you have infection or delayed healing of the injection sites. Immune-mediated events may occur while receiving talimogene laherparepvec. These include glomerulonephritis, pneumonitis, psoriasis, vasculitis, or vitiligo. Tell your doctor if you have bloody or cloudy urine, swelling of the feet or lower legs, weight gain, fever, sores, welting, or blisters, or red, scaling, or crusted skin. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. talimogene laherparepvec Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Chills cough diarrhea fever general feeling of discomfort or illness headache joint pain loss of appetite muscle aches and pains nausea pain at the injection site runny nose shivering sore throat sweating trouble sleeping unusual tiredness or weakness vomiting Incidence not known Break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid burning or stinging of the skin painful cold sores or blisters on the lips, nose, eyes, or genitals Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain difficulty having a bowel movement (stool) difficulty with moving dizziness muscle pain or stiffness pain in the arms or legs weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about talimogene laherparepvec Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: miscellaneous antineoplastics Consumer resources Talimogene laherparepvec Other brands: Imlygic Professional resources Talimogene Laherparepvec (AHFS Monograph) Talimogene Laherparepvec (Wolters Kluwer) Related treatment guides Melanoma Melanoma, Metastatic} Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Drug Class Miscellaneous antineoplastics Related Drugs Melanoma, Metastatic Opdivo , Keytruda , nivolumab , pembrolizumab , Yervoy , ipilimumab , Tafinlar , Mekinist , trametinib , dabrafenib , Proleukin , dacarbazine , More... Melanoma Opdivo , Keytruda , nivolumab , pembrolizumab , Yervoy , ipilimumab , Proleukin , dacarbazine , Intron A , Sylatron , aldesleukin , interferon alfa-2b , More... Talimogene laherparepvec Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the talimogene laherparepvec support group to connect with others who have similar interests.} } grow old
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