Francis Bacon Antagon (Subcutaneous) Generic Name: ganirelix (Subcutaneous route) ga-ni-REL-ix Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Antagon Available Dosage Forms: Solution Therapeutic Class: Endocrine-Metabolic Agent Pharmacologic Class: Luteinizing Hormone Releasing Hormone Antagonist Slideshow Inherited Risk: The BRCA Gene Explained Uses For Antagon Ganirelix injection is used as a fertility medicine to prevent premature luteinizing hormone (LH) surges or ovulation in women undergoing fertility treatment of controlled ovarian hyperstimulation. It may also help reduce the need for follicle-stimulating hormone (FSH), which is also needed for ovulation. Ganirelix is a gonadotropin-releasing hormone (GnRH) antagonist. This medicine is available only with your doctor's prescription. Before Using Antagon In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric No information is available on the relationship of age to the effects of ganirelix injection in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ganirelix injection in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Proper Use of Antagon To make using ganirelix as safe and reliable as possible, you should understand how and when to use this medicine and what effects may be expected. A patient information leaflet will be given to you with your filled prescription and will provide many details concerning the use of ganirelix. Read the information carefully and ask your doctor for any additional information or explanation. Sometimes ganirelix can be given by injection at home. If you are using this medicine at home: Understand and use the proper method of safely preparing the medicine if you are going to prepare your own medicine. Wash your hands with soap and water and use a clean work area to prepare your injection. Make sure you clearly understand and carefully follow your doctor's instructions on how to give yourself an injection, including using the proper needle and syringe. Do not inject more or less of the medicine than your doctor ordered. Remember to move the site of injection to different areas to prevent skin problems from developing. Throw away needles, syringes, bottles, and unused medicine after the injection in a safe manner. Tell your doctor when you use your last dose of ganirelix. Your doctor will give you another medicine called human chorionic gonadotrophin (hCG) or arrange for you to get this medicine at the right time. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For injection dosage form: For treatment of female infertility: Adults After receiving FSH treatment on Day 2 or 3 of your menstrual cycle, 250 micrograms (mcg) of ganirelix is injected under the skin once a day during the mid to late follicular phase (about Day 7 or 8 up to Day 12 or 13 of your menstrual cycle). Children Use is not recommended. Missed Dose Call your doctor or pharmacist for instructions. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Throw away used needles and syringes in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets. Ask your pharmacist, doctor, or nurse about the best way to dispose of any leftover medicine and other supplies. Precautions While Using Antagon It is very important that your doctor check your progress often at regular visits to make sure that the medicine is working properly and to check for unwanted effects. Your doctor will probably want to follow the developing eggs inside the ovaries by doing an ultrasound examination and measuring hormones in your blood stream. This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. The needle cover of the prefilled syringe contains dry natural rubber (a derivative of latex), which may cause allergic reactions in people who are sensitive to latex. Tell your doctor if you have a latex allergy before you start using this medicine. If your doctor has asked you to record your basal body temperatures (BBTs) daily, make sure that you do this every day. Using a BBT record or some other method, your doctor will help you decide when you are most fertile and when ovulation occurs. It is important that sexual intercourse take place around the time when you are most fertile to give you the best chance of becoming pregnant. Follow your doctor's directions carefully. If severe abdominal pain occurs with use of ganirelix, discontinue treatment and report the problem to your doctor immediately. Do not receive the injection of human chorionic gonadotropin (hCG) and avoid sexual intercourse. Antagon Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Abdominal or stomach pain bloating diarrhea rapid weight gain Rare Cough difficulty with swallowing dizziness fast heartbeat puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue shortness of breath skin rash, hives, or itching tightness in the chest unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Headache redness, pain, or swelling at the injection site Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Antagon (ganirelix) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: gonadotropin-releasing hormone antagonists Consumer resources Antagon Professional resources Ganirelix Acetate (AHFS Monograph) Related treatment guides Gonadotropin Inhibition} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Drug Class Gonadotropin-releasing hormone antagonists Related Drugs Gonadotropin Inhibition Sprintec , Ortho Tri-Cyclen , TriNessa , Mononessa , Tri-Sprintec , ethinyl estradiol / norgestimate , Ortho Tri-Cyclen Lo , Zovia , Ortho Cyclen , Mono-Linyah , Previfem , TriNessa Lo , Tri-Previfem , Estarylla , Tri-Lo-Sprintec , Tri-Linyah , ganirelix , Necon 1 / 50 , Zovia 1 / 50 , Kelnor 1 / 35 , Tri-Lo-Marzia , More... Antagon Rating No Reviews - Be the first! 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