footslogging away Sodium Chromate CR 51 Dosage Form: injection Professional Reviews Q & A More Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here. Sodium Chromate 51 Per your order, we have compounded Chromium 51 as a sterile intravenous injectable dispensed as 1 mL in a 5 mL vial. The characteristics of this preparation are described below Slideshow FDA-Approved Weight Loss Drugs: Can They Help You? Sodium Chromate CR 51 Description AnazaoHealth s compounded Cr-51 vial is a sterile, non-pyrogenic diagnostic radiopharmaceutical that consists up to 1 mCi of Cr-51 (precalibrated) in a volume up to 5 mL normal saline and 6 mg/mL benzyl alcohol. Indications and Usage for Sodium Chromate CR 51 Cr51 is indicated for use in determining red blood cell volume or mass, studying red blood cell survival time (in conditions such as hemolytic anemia), and evaluating blood loss Mechanism of Action The chromium in this agent is present as the dianionic chromate ion in which form it appears to bind to the red blood cell in two steps, initially by a rapid but reversible attachment to the cell membrane followed by a slower nearly irreversible binding to intracellular hemoglobin and reduction to the anionic state. It has been suggested that the slow rate of uptake is dependent on the rate at which chromate can penetrate the cell membrane. Binding is maintained until the red blood cells are sequestered by the spleen or until elution of the chromium occurs into the plasma. The chromium is then readily excreted mainly in the urine. Once liberated by elution or erythrocyte senescence, chromium 51 is not available for relabeling of red cells. In normal individuals the erythrocyte survival half-time T as measured by the chromium 51 "random labeling" technique, generally ranges between 25 and 35 days. This apparent short survival time, when compared to the 120 day life span of the red blood cells, is due to the elution of chromium from the cells and to cell damage that probably occurs during the process of withdrawing them from the body and labeling. Subnormal T may be indicative of blood toss, sequestration of red blood cells by the spleen, or shortened cell viability, as occurs In hemolytic anemia Contraindications There are no known contraindications for this preparation Sodium Chromate CR 51 Dosage and Administration The suggested dose range in the average patient (70kg) is: Determination of red blood cell volume or mass-0.37 to 1.11 megabecquerels (10 to 30 microcuries). Study of red blood cell survival time-5.55 megabecquerels (150 microcuries). Evaluation of blood loss-7.40 megabecquerels (200 microcuries) Figure 1 PACKAGE LABEL.PRINCIPAL DISPLAY PANEL Figure 2 SODIUM CHROMATE 51 sodium chromate 51 solution Product Information Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:51808-101 Route of Administration INTRAVENOUS DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength CHROMIUM CR-51 (CHROMIUM CR-51) CHROMIUM CR-51 1 mCi in 5 mL Inactive Ingredients Ingredient Name Strength BENZYL ALCOHOL 30 mg in 5 mL SODIUM CHLORIDE Packaging # Item Code Package Description 1 NDC:51808-101-02 5 mL in 1 VIAL Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date Unapproved drug other 06/19/2012 Labeler - AnazaoHealth Corporation (011038762) Establishment Name Address ID/FEI Operations AnazaoHealth Corporation 011038762 MANUFACTURE(51808-101) Revised: 06/2012 AnazaoHealth Corporation Next User Reviews Print this page Add to My Med List More about sodium chromate cr-51 Support Group 0 Reviews Add your own review/rating Drug class: diagnostic radiopharmaceuticals Professional resources Other brands: Chromitrope Sodium FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Diagnostic radiopharmaceuticals Related Drugs diagnostic radiopharmaceuticals Xofigo , sodium fluoride f-18 , indium oxyquinoline in-111 , fludeoxyglucose f18 , Vizamyl Sodium chromate cr-51 Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! is attempting
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