doping up Droxia (Oral) Generic Name: hydroxyurea (Oral route) hye-drox-ee-ure-EE-a Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Oral route(Capsule) Hydroxyurea may cause severe myelosuppression. Monitor blood counts at baseline and throughout treatment. Interrupt treatment and reduce dose as necessary. Hydroxyurea is carcinogenic. Advise sun protection and monitor patients for malignancy . Commonly used brand name(s) In the U.S. Droxia Hydrea Available Dosage Forms: Capsule Tablet Therapeutic Class: Antineoplastic Agent Pharmacologic Class: Antimetabolite Slideshow It's In The Genes - Record Your Family Health History Uses For Droxia Hydroxyurea is used to treat cancer of the white blood cells called chronic myeloid leukemia (CML). It may also be given together with radiation treatment for head and neck cancer (advanced squamous cell cancer). Hydroxyurea interferes with the growth of cancer cells, which are eventually destroyed by the body. Hydroxyurea is used in adult patients with sickle cell anemia to prevent painful episodes and reduce the need for blood transfusions. It works by making the red blood cells more flexible. This medicine is available only with your doctor's prescription. Before Using Droxia In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of hydroxyurea in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydroxyurea in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving hydroxyurea. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Measles Virus Vaccine, Live Mumps Virus Vaccine, Live Rotavirus Vaccine, Live Rubella Virus Vaccine, Live Varicella Virus Vaccine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Adenovirus Vaccine Bacillus of Calmette and Guerin Vaccine, Live Cholera Vaccine, Live Didanosine Influenza Virus Vaccine, Live Poliovirus Vaccine, Live Smallpox Vaccine Stavudine Typhoid Vaccine Yellow Fever Vaccine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Anemia (low red blood cells) or Bone marrow problems or HIV infection or Leukopenia (low white blood cells) or Thrombocytopenia (low blood platelet levels) Use with caution. May make these conditions worse. Kidney disease, severe Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of hydroxyurea This section provides information on the proper use of a number of products that contain hydroxyurea. It may not be specific to Droxia. Please read with care. Use this medicine exactly as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions. Your doctor may want you to take folic acid with this medicine. Hydroxyurea should be handled with care. People who are not taking this medicine should avoid touching it. To decrease your chance of touching the medicine: Wear disposable gloves when handling the bottle or capsules. Wash your hands with soap and water before and after contact with the bottle or capsules. Do not open the capsules. Avoid exposure to crushed or opened capsules. If you touch an opened or crushed capsule, wash your skin right away with soap and water. If powder from the capsule gets into your eyes, rinse them with water or an isotonic eyewash for 15 minutes. If powder from the capsule is spilled, wipe it up right away with a damp disposable towel. Place the towel and the empty capsule in a closed container, such as a plastic bag. The area where the powder spilled should be cleaned 3 times using a detergent solution followed by clean water. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (capsules): For cancer of the head and neck: Adults Dose is based on body weight and must be determined by your doctor. The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed. Children Use and dose must be determined by your doctor. For chronic myelocytic leukemia (CML): Adults Dose is based on body weight and must be determined by your doctor. The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed. Children Use and dose must be determined by your doctor. For sickle cell anemia: Adults Dose is based on body weight and must be determined by your doctor. At first, the dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Droxia It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby. Women should use an effective form of birth control during treatment and for at least 6 months after the last dose. Men should use an effective form of birth control during treatment and for at least 1 year after the last dose to prevent pregnancy in a sexual partner. If a pregnancy occurs while using the medicine, tell your doctor right away. Hydroxyurea can temporarily lower the number of white blood cells in your blood which increases the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding: If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin. Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters. Avoid contact sports or other situations where bruising or injury could occur. Using this medicine for a long time may increase your risk of developing leukemia (cancer of the blood) or skin cancer. Use a sunscreen and protective clothing to protect your skin. Talk to your doctor if you have concerns about this risk. If you had radiation treatment in the past, this medicine might cause your skin to become very red when you have radiation again. Tell your doctor right away if you have darkening or redness of the skin. While you are being treated with hydroxyurea, do not have any immunizations (vaccinations) without your doctor's approval. Live virus vaccinations (eg, nasal flu virus vaccine) should not be given while receiving hydroxyurea. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before you have medical tests. Talk with your doctor before using this medicine if you plan to have children. Some men who use this medicine have become infertile (unable to have children). Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Droxia Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Cough or hoarseness fever or chills lower back or side pain painful or difficult urination Less common Black, tarry stools blackening of the fingernails and toenails blood in the urine or stools pinpoint red spots on the skin sores in the mouth and on the lips unusual bleeding or bruising Rare Confusion convulsions (seizures) difficulty with urination dizziness headache joint pain seeing, hearing, or feeling things that are not there swelling of the feet or lower legs Incidence not known Bleeding under the skin blisters on the skin bluish or pale color on the skin of the fingers or toes coldness of the fingers or toes crater-like lesions on the skin itching skin numbness or tingling of the fingers or toes pain in the fingers or toes unusual tiredness or weakness weight loss Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Diarrhea drowsiness loss of appetite nausea or vomiting Less common Constipation redness of skin at the place of radiation skin rash and itching Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Droxia (hydroxyurea) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: antimetabolites Consumer resources Droxia Other brands: Hydrea Professional resources Droxia (FDA) Hydroxyurea (AHFS Monograph) Related treatment guides Anemia, Sickle Cell Solid Tumors} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug 10 + years Approval History FDA approved 1967 Manufacturer Bristol-Myers Squibb Company Drug Class Antimetabolites Related Drugs Anemia, Sickle Cell vitamin e , hydroxyurea , Hydrea , glutamine , Alpha E , E-400 Clear , Endari , Aquasol E , More... Solid Tumors methotrexate , hydroxyurea , Hydrea , Keytruda , pembrolizumab , Trexall , idarubicin , Idamycin , More... Droxia Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Droxia Images Droxia 200 mg (DROXIA 6335 DROXIA 6335) View all images Related Questions & Answers Can you take Droxia 200 mg instead of Hydrea 500 mg? Read more questions} } right now
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