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the cause of the pain Arranon Generic Name: Nelarabine (nel AY re been) Brand Name: Arranon Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Warning This medicine may cause very bad nervous system problems. Sometimes, nervous system problems have not gone away even after treatment with Arranon (nelarabine) was stopped. Call your doctor right away if you feel very sleepy or confused, or are not able to move. Call your doctor right away if you have a burning, numbness, or tingling feeling that is not normal; a change in balance; problems with daily living like buttoning clothes; seizures; tripping when walking; or weakness. Uses of Arranon: It is used to treat a type of leukemia. It is used to treat a type of lymphoma. Slideshow Checkpoint Inhibitors & Advanced Cancers: A Healthcare Professional's Guide What do I need to tell my doctor BEFORE I take Arranon? If you have an allergy to nelarabine or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are taking pentostatin. If you are breast-feeding. Do not breast-feed while you take Arranon. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Arranon with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Arranon? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Avoid driving and doing other tasks or actions that call for you to be alert until you see how Arranon affects you. The ability of your bone marrow to make blood cells may be lowered. This can lead to very bad bleeding problems or infections. Tell your doctor right away if you have signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if you feel very tired or weak. You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects. If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. Have blood work checked as you have been told by the doctor. Talk with the doctor. Talk with your doctor before getting any vaccines. Use with this medicine may either raise the chance of an infection or make the vaccine not work as well. If you are 65 or older, use Arranon with care. You could have more side effects. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Use birth control that you can trust to prevent pregnancy while taking this medicine. If you are pregnant or you get pregnant while taking Arranon, call your doctor right away. How is this medicine (Arranon) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. It is given as an infusion into a vein over a period of time. Other drugs will be given with Arranon to help avoid side effects. Drink lots of noncaffeine liquids every day unless told to drink less liquid by your doctor. What do I do if I miss a dose? Call your doctor to find out what to do. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal. Signs of dehydration like dry skin, mouth, or eyes; thirst; fast heartbeat; dizziness; fast breathing; or confusion. Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit. Shortness of breath. Pale skin. Any unexplained bruising or bleeding. Feeling very tired or weak. Muscle pain or weakness. Chest pain or pressure or a fast heartbeat. Swelling in the arms or legs. Low mood (depression). Very bad dizziness or passing out. Patients with cancer who take this medicine may be at a greater risk of getting a bad health problem called tumor lysis syndrome (TLS). Sometimes, this has been deadly. Call your doctor right away if you have a fast heartbeat or a heartbeat that does not feel normal; any passing out; trouble passing urine; muscle weakness or cramps; upset stomach, throwing up, loose stools, or not able to eat; or feel sluggish. What are some other side effects of Arranon? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling sleepy. Dizziness. Feeling tired or weak. Upset stomach or throwing up. Hard stools (constipation). Loose stools (diarrhea). Headache. Joint pain. Back pain. Stomach pain. Mouth irritation or mouth sores. Swelling of belly. Not hungry. Not able to sleep. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Arranon? If you need to store Arranon (nelarabine) at home, talk with your doctor, nurse, or pharmacist about how to store it. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take Arranon or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Arranon. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about Arranon (nelarabine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En EspaƱol 0 Reviews Add your own review/rating Drug class: antimetabolites Consumer resources Arranon Arranon (Advanced Reading) Professional resources Arranon (AHFS Monograph) Arranon (FDA) Related treatment guides Acute Lymphoblastic Leukemia Lymphoma} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Arranon Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Manufacturer Novartis Pharmaceuticals Corporation Drug Class Antimetabolites Related Drugs Acute Lymphoblastic Leukemia methotrexate , Gleevec , mercaptopurine , imatinib , Adriamycin , doxorubicin , Sprycel , Trexall , dasatinib , Purinethol , Kymriah , More... Lymphoma prednisone , methotrexate , dexamethasone , Decadron , Deltasone , Revlimid , cortisone , Imbruvica , Adriamycin , doxorubicin , Velcade , More...} } cost


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