mesmerizing Chlorhexidine use while Breastfeeding color

stepping into Chlorhexidine use while Breastfeeding look
 
Photo :Chlorhexidine use while Breastfeeding

inspired Chlorhexidine use while Breastfeeding Drugs containing Chlorhexidine: Peridex, Hibiclens, Periogard, ChloraPrep One-Step, Paroex, Chlorostat, Perisol, Tegaderm CHG Dressing, Dyna-Hex, Betasept, Show all 23 PerioChip, Hibistat, Calgon Vesta, Bactoshield, Scrub Care Exidine, Chlorostat 4, Hibistat Towelette, Spectrum-4, Acclean, Biopatch, Denti-Rinse, Exidine, Scrub Care Overview Side Effects Dosage Professional Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Compare Alternatives Pricing & Coupons Chlorhexidine Levels and Effects while Breastfeeding Summary of Use during Lactation Chlorhexidine has been used vaginally or topically on the abdomen or perineum prior to delivery to prevent infection. No toxicity has been reported in breastfed infants and it has clearly less toxicity compared to povidone-iodine in these situations. Topical application of chlorhexidine to the breast before and after nursing did not appear to adversely affect the breastfed infants in one study. Use of chlorhexidine oral rinse by a nursing mother is unlikely to adversely affect her infant. Drug Levels Maternal Levels. Iodine milk levels were measured in a study of mothers who received 10% povidone-iodine (n = 21) or chlorhexidine (n = 13) topically to the perineum starting immediately before the final stage of labor and daily postpartum to the episiotomy. At 96 hours postpartum, milk iodine levels averaged 1.2 mg/L in mothers who received topical povidone-iodine compared to average milk levels of 0.1 mg/L in the mothers who received chlorhexidine.[1] Infant Levels. In a study of mothers who received 10% povidone-iodine (n = 21) or chlorhexidine (n = 13) topically to the perineum starting immediately before the final stage of labor and daily postpartum to the episiotomy, urine iodine levels were measured in their infants. In the infants whose mothers received povidone-iodine, urine iodine levels were much higher at 24 and 48 hours postpartum. At 96 hours postpartum, the breastfed infants (n = 13) whose mothers received povidone-iodine had urine iodine levels of 8.3 mg/L compared to levels of 0.4 mg/L in infants who did not breastfeed (n = 8) and 0.6 mg/L in the infants of mothers who received chlorhexidine (n = 13).[1] Effects in Breastfed Infants A group of investigators in Belgium reviewed the results of infant thyrotropin levels on day 5 postpartum in 4745 newborn infants delivered over a 2-year period at their hospital. Infants were divided among those whose mothers had iodine overload (n = 3086) from topical povidone-iodine 10% solution during labor and delivery and those whose mothers had no iodine overload (n = 1659). Mothers had povidone-iodine applied either as a single application to 900 square cm for epidural anesthesia or 3 applications to the entire abdominal wall for cesarean section. Breastfed infants whose mothers had iodine overload had a greater risk for having elevated thyrotropin levels and requiring recall for retesting (3.2% with cesarean section and 2.7% with epidural anesthesia) compared to those who did not (0.1%). Bottle-fed infants were affected much less than breastfed infants.[2] After replacing povidone-iodine with chlorhexidine 0.5% in 70% isopropanol for disinfection for 6 months, 1178 infants that were delivered at this institution had no increased rate of elevations in thyroid function tests and a reduced rate of recalls in breastfed infants.[3] In a study of mothers in Spain who received 10% povidone-iodine (n = 21) or chlorhexidine (n = 13) topically to the perineum starting immediately before the final stage of labor and daily postpartum to the episiotomy, no differences in thyrotropin, thyroxine or free thyroxine was found among their breastfed infants at day 5 to 7 postpartum.[1] Studies in Africa have used chlorhexidine vaginally prior to delivery in an attempt to reduce the frequency of mother-to-child transmission (MTCT) of HIV. In one, cotton soaked in 0.25% chlorhexidine solution was used to swab the vaginal walls every 4 hours from admission into labor until delivery in 4078 women.[4] The other study used 120 mL of either 0.2% or 0.4% chlorhexidine solution as a vaginal lavage every 3 hours from admission to labor until delivery in 309 women. The average number of lavages was 2.1 (range 1 to 11).[5] Chlorhexidine 0.25% swabs reduced MTCT in patients whose membranes ruptured more than 4 hours before delivery, but not in other women. Vaginal lavage showed a statistically nonsignificant trend towards reduction of MTCT, with the 0.4% greater than the 0.2%. Almost all of the infants in these studies were breastfed. No adverse events were reported in the infants, but follow-up related primarily to infant mortality and HIV status rather than effects of chlorhexidine. Effects on Lactation and Breastmilk A randomized study compared 0.2% chlorhexidine in alcohol to distilled water as a spray to the breast in 200 mothers who were nursing newborns. The mothers sprayed their breasts with the liquid before and after each feeding. Mothers and infants were assessed at discharge and weekly thereafter. Discomfort and nipple trauma were less frequent in the chlorhexidine group than in the placebo group, particularly at the first assessment. Although skin flora on the breasts of the treated mothers was reduced, there was no difference in the frequency of mastitis between the treated and placebo groups. No obvious side effects occurred in the breastfed infants and there were no differences in the rates of oral thrush in infants between the treatments.[6] A systematic review concluded that this practice is not justified based on current evidence.[7] Alternate Drugs to Consider Benzalkonium Chloride References 1. Arena Ansotegui J, Emparanza Knorr JI, San Millan Vege MJ et al. [Iodine overload in newborn infants caused by the use of PVP-iodine for perineal preparation of the mother in vaginal delivery]. An Esp Pediatr. 1989;30:23-6. PMID: 2648916 2. Chanoine JP, Boulvain M, Bourdoux P et al. Increased recall rate at screening for congenital hypothyroidism in breast fed infants born to iodine overloaded mothers. Arch Dis Child. 1988;63:1207-10. PMID: 3196047 3. Chanoine JP, Pardou A, Bourdoux P, Delange F. Withdrawal of iodinated disinfectants at delivery decreases the recall rate at neonatal screening for congenital hypothyroidism. Arch Dis Child. 1988;63:1297-8. Letter. PMID: 3196066 4. Biggar RJ, Miotti PG, Taha TE et al. Perinatal intervention trial in Africa: effect of a birth canal cleansing intervention to prevent HIV transmission. Lancet. 1996;347:1647-50. PMID: 8642957 5. Gaillard P, Mwanyumba F, Verhofstede C et al. Vaginal lavage with chlorhexidine during labour to reduce mother-to-child HIV transmission: clinical trial in Mombasa, Kenya. AIDS. 2001;15:389-96. PMID: 11273219 6. Herd B, Feeney JG. Two aerosol sprays in nipple trauma. Practitioner. 1986;230:31-8. PMID: 3513148 7. Vieira F, Bachion MM, Mota DD, Munari DB. A systematic review of the interventions for nipple trauma in breastfeeding mothers. J Nurs Scholarsh. 2013;45:116-25. PMID: 23452043 Chlorhexidine Identification Substance Name Chlorhexidine CAS Registry Number 55-56-1 Drug Class Antiinfective Agents, Local Antibacterial Agents Disinfectants Mouthwashes Administrative Information LactMed Record Number 494 Last Revision Date 20150310 Disclaimer Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site. Print this page Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy. More about chlorhexidine topical Side Effects During Pregnancy or Breastfeeding Dosage Information Compare Alternatives Support Group Pricing & Coupons 22 Reviews Add your own review/rating Drug class: antiseptic and germicides Consumer resources Chlorhexidine gluconate oral rinse Chlorhexidine topical Chlorhexidine Gluconate Oral Solution Chlorhexidine Gluconate Topical Chlorhexidine (Advanced Reading) ... +2 more Other brands: Peridex , Hibiclens , Periogard , Tegaderm CHG Dressing , ... +12 more Professional resources Chlorhexidine Gluconate eent (AHFS Monograph) ... +4 more Related treatment guides Gingivitis Mucositis Skin Disinfection, Preoperative Periodontitis} Drug Status Rx OTC Availability Rx and/or OTC C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Chlorhexidine topical Rating 22 User Reviews 7.6 /10 22 User Reviews 7.6 Rate it! Drug Class Antiseptic and germicides Mouth and throat products} } the most effective


special effects Chlorhexidine use while Breastfeeding most excellent


EmoticonEmoticon