continuously Emend (Intravenous) Generic Name: fosaprepitant (Intravenous route) fos-a-PRE-pi-tant dye-MEG-loo-meen Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Emend Available Dosage Forms: Powder for Solution Therapeutic Class: Antiemetic Pharmacologic Class: Fosaprepitant Slideshow Understanding Insulin: What You Need To Know Uses For Emend Fosaprepitant injection is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy). It acts in the brain to prevent nausea. This medicine is available only with your doctor's prescription. Before Using Emend In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of fosaprepitant injection in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fosaprepitant injection in the elderly. However, elderly patients are more likely to have liver, kidney, or heart problems, which may require caution in patients receiving this medicine. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Flibanserin Lomitapide Pimozide Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Atazanavir Boceprevir Bosutinib Brexpiprazole Carbamazepine Ceritinib Cilostazol Clarithromycin Cobicistat Cobimetinib Colchicine Conivaptan Dasatinib Diltiazem Docetaxel Domperidone Doxorubicin Doxorubicin Hydrochloride Liposome Dronedarone Enzalutamide Eplerenone Erythromycin Fluconazole Fosphenytoin Hydrocodone Ibrutinib Idelalisib Ifosfamide Imatinib Indinavir Itraconazole Ivabradine Ivacaftor Ketoconazole Lopinavir Lumacaftor Lurasidone Mitotane Naloxegol Nefazodone Nelfinavir Olaparib Oxycodone Phenytoin Piperaquine Posaconazole Ranolazine Rifampin Ritonavir Saquinavir Simeprevir Sonidegib St John's Wort Tacrolimus Telaprevir Telithromycin Tolvaptan Venetoclax Verapamil Voriconazole Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Desogestrel Dexamethasone Dienogest Drospirenone Estradiol Cypionate Estradiol Valerate Ethinyl Estradiol Ethynodiol Diacetate Etonogestrel Levonorgestrel Medroxyprogesterone Acetate Mestranol Midazolam Norelgestromin Norethindrone Norgestimate Norgestrel Quetiapine Suvorexant Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Proper Use of Emend A nurse or other trained health professional will give you this medicine in a hospital or clinic. This medicine is given through a needle placed in one of your veins. The infusion may take up to 30 minutes. This medicine is usually given on the first day of your chemotherapy along with other medicines. Fosaprepitant is not for long-term use, but you may need to use this medicine again if you have more chemotherapy in the future. This medicine comes with a patient information insert. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand. Precautions While Using Emend It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. You should not receive this medicine if you are also using pimozide (Orap ). Fosaprepitant may cause serious or life-threatening problems if used together with this medicine. This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have itching, hives, a rash, trouble breathing, trouble swallowing, warmth or redness in your face, neck, arms, or upper chest, or any swelling of your hands, face, or mouth while you are receiving this medicine. If you are also using a blood thinner called warfarin (Coumadin , Jantoven ), your doctor will need to check your blood after using this medicine. Birth control pills may not work as well while you are using fosaprepitant. To keep from getting pregnant, use another form of birth control together with your pills during treatment and for one month after your last treatment. Other forms include condoms, a diaphragm, and contraceptive foam or jelly. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Emend Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Black, tarry stools blurred vision chills confusion cough decreased urination difficult or labored breathing dizziness dry mouth fainting fever increase in heart rate lightheadedness lower back or side pain nervousness pain, swelling, or redness at the injection site painful or difficult urination pale skin pounding in the ears rapid breathing slow or fast heartbeat sore throat sunken eyes tenderness, swelling, warmth, or skin discoloration at the injection site thirst tightness in the chest ulcers, sores, or white spots in the mouth unusual bleeding or bruising unusual tiredness or weakness wrinkled skin Less common Hard lump at the injection site Rare Blood in the urine changes in patterns and rhythms of speech changes in skin color chest pain or discomfort coma convulsions fast, slow, irregular, pounding, or racing heartbeat or pulse general feeling of discomfort or illness headache increased sweating increased thirst lightheadedness, dizziness, or fainting muscle pain or cramps nausea or vomiting pain, tenderness, or swelling of the foot or leg slurred speech swelling swelling of the face, ankles, or hands trouble with speaking troubled breathing with exertion Incidence not known Difficulty with swallowing hives or welts, itching large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness of the skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach belching burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings continuing ringing or buzzing or other unexplained noise in ears diarrhea difficulty having a bowel movement (stool) dizziness feeling of indigestion hair loss or thinning of the hair hearing loss hiccups indigestion lack or loss of strength loss of appetite pain in the chest below the breastbone stomach discomfort, upset, or pain swelling or inflammation of the mouth weight loss Less common Feeling of warmth pain or discomfort in chest, upper stomach, or throat redness of the face, neck, arms, and occasionally, upper chest sudden sweating unusually warm skin Rare Abdominal or stomach distension or pain abnormal dreams blemishes on the skin bumps on the skin burning, dry, or itching eyes change in taste change in walking and balance clumsiness or unsteadiness confusion about identity, place, and time difficulty with moving discharge, excessive tearing excess air or gas in the stomach extreme thirst false or unusual sense of well-being flushed, dry skin frequent urination fruit-like breath odor full feeling heartburn increased hunger increased sensitivity of the skin to sunlight increased urination increased volume of pale, dilute urine joint pain muscle aching or cramping muscle stiffness or weakness oily skin passing gas pimples redness or other discoloration of the skin redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid severe constipation severe sunburn sleepiness sweating swollen joints trouble performing routine tasks trouble sleeping unexplained weight loss unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness weight gain white patches in the mouth or throat or on the tongue white patches with diaper rash Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about fosaprepitant Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 1 Review Add your own review/rating Drug class: NK1 receptor antagonists Consumer resources Fosaprepitant Fosaprepitant Intravenous (Advanced Reading) Other brands: Emend for Injection Professional resources Fosaprepitant (Wolters Kluwer) Related treatment guides Nausea/Vomiting, Chemotherapy Induced} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class NK1 receptor antagonists Related Drugs Nausea / Vomiting, Chemotherapy Induced lorazepam , ondansetron , Zofran , Ativan , dexamethasone , metoclopramide , Reglan , Decadron , Marinol , dronabinol , Zofran ODT , Emend , Aloxi , granisetron , Varubi , palonosetron , Kytril , aprepitant , Akynzeo , fosaprepitant , Dexasone , nabilone , More... 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