abruptly emtricitabine and tenofovir alafenamide (Oral route) em-trye-SYE-ta-been, ten-OF-oh-vir al-a-FEN-a-mide Oral route(Tablet) Emtricitabine/tenofovir alafenamide is not approved for the treatment of chronic hepatitis B virus (HBV) infection. Severe acute exacerbations of hepatitis B have been reported in patients who are coinfected with HIV-1 and HBV and have discontinued products containing emtricitabine (FTC) and/or tenofovir disoproxil fumarate (TDF), and may occur with discontinuation of emtricitabine/tenofovir alafenamide. Hepatic function should be monitored closely in these patients. If appropriate, initiation of antihepatitis B therapy may be warranted . Overview Side Effects Interactions Pregnancy Reviews More Support Group Q & A Commonly used brand name(s) In the U.S. Descovy Available Dosage Forms: Tablet Therapeutic Class: Antiretroviral Agent Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor Slideshow Think Before You Ink: Health Risks Associated With Tattoos Uses For emtricitabine and tenofovir alafenamide Emtricitabine and tenofovir alafenamide combination is used together with other medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). emtricitabine and tenofovir alafenamide will not cure HIV infection or AIDS. It works by lowering the amount of HIV in the blood and helps the immune system. This may help delay some of the medical conditions that usually result from AIDS or HIV disease. It will not keep you from spreading HIV to other people. emtricitabine and tenofovir alafenamide is available only with your doctor's prescription. Before Using emtricitabine and tenofovir alafenamide In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For emtricitabine and tenofovir alafenamide, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to emtricitabine and tenofovir alafenamide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of emtricitabine and tenofovir alafenamide combination in children younger than 12 years of age with body weight of less than 35 kilograms (kg). Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of emtricitabine and tenofovir alafenamide combination in the elderly. Breast Feeding Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using emtricitabine and tenofovir alafenamide. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking emtricitabine and tenofovir alafenamide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using emtricitabine and tenofovir alafenamide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Carbamazepine Orlistat Oxcarbazepine Phenobarbital Phenytoin Rifabutin Rifampin Rifapentine St John's Wort Tipranavir Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of emtricitabine and tenofovir alafenamide. Make sure you tell your doctor if you have any other medical problems, especially: Bone fracture, history of or Fanconi syndrome (kidney disease), history of or Hepatitis B infection, history of or Kidney failure, history of or Liver disease, history of or Osteomalacia (soft bones), history of or Osteoporosis (weak or brittle bones), history of Use with caution. May make these conditions worse. Kidney disease, severe Use is not recommended in patients with these conditions. Proper Use of emtricitabine and tenofovir alafenamide Take emtricitabine and tenofovir alafenamide exactly as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Keep taking emtricitabine and tenofovir alafenamide for the full time of treatment , even if you begin to feel better. Do not stop taking it without checking first with your doctor. When your supply of the medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of the medicine. emtricitabine and tenofovir alafenamide comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions. You may take the medicine with or without food. Swallow the tablet whole. Do not crush, break, or chew it. Dosing The dose of emtricitabine and tenofovir alafenamide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of emtricitabine and tenofovir alafenamide. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For treatment of HIV infection: Adults and children 12 years of age and older and weighs at least 35 kilograms (kg) One tablet once per day. Children younger than 12 years of age or weighs less than 35 kg Use and dose must be determined by your doctor. Missed Dose If you miss a dose of emtricitabine and tenofovir alafenamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep the medicine in the original bottle that you were given at the pharmacy and keep it tightly closed. Precautions While Using emtricitabine and tenofovir alafenamide It is very important that your doctor check your progress at regular visits to make sure emtricitabine and tenofovir alafenamide is working properly. Blood and urine tests may be needed to check for unwanted effects. emtricitabine and tenofovir alafenamide may cause a rare, but serious, unwanted effect called lactic acidosis (too much acid in the blood) and liver toxicity. These reactions are more common if you are female, obese, or have been taking anti-HIV medicines for a long time. Call your doctor right away if you have abdominal or stomach discomfort, a decreased appetite, diarrhea, fast and shallow breathing, a general feeling of discomfort, muscle pain or cramping, nausea, shortness of breath, sleepiness, or unusual tiredness or weakness. emtricitabine and tenofovir alafenamide may cause rare, but serious, liver problems. This is more common in patients with a history of hepatitis B infection or those who already have liver disease. Check with your doctor right away if you have clay-colored stools, dark urine, a decreased appetite, a fever, a headache, itching, nausea and vomiting, a skin rash, stomach pain or tenderness, swelling of the feet or lower legs, unusual tiredness or weakness, or yellow eyes or skin. Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis. Autoimmune disorders such as Graves disease, polymyositis, and Guillain-Barré syndrome may also occur. emtricitabine and tenofovir alafenamide may cause your bones to get weak and brittle. This could increase your risk for broken bones (fractures). Ask your doctor about this if you have any concerns. emtricitabine and tenofovir alafenamide does not decrease the risk of transmitting the HIV infection to others through sexual contact or by contaminated blood. Make sure you understand and practice safe sex, even if your partner also has HIV. Avoid sharing needles with anyone. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements. emtricitabine and tenofovir alafenamide Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Incidence not known Abdominal or stomach discomfort bloody urine bone pain dark urine decreased appetite decreased frequency or amount of urine diarrhea fast, shallow breathing general feeling of discomfort increased thirst light-colored stools loss of appetite lower back or side pain muscle pain or cramping nausea and vomiting shortness of breath sleepiness swelling of the face, fingers, or lower legs troubled breathing unusual tiredness or weakness upper right abdominal or stomach pain weight gain yellow eyes and skin Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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Next Side Effects Print this page Add to My Med List More about emtricitabine/tenofovir alafenamide Side Effects During Pregnancy Drug Interactions Support Group 1 Review Add your own review/rating Drug class: antiviral combinations Consumer resources Emtricitabine and Tenofovir Alafenamide Other brands: Descovy Professional resources Related treatment guides HIV Infection} Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Antiviral combinations Related Drugs HIV Infection Truvada , Atripla , Norvir , Viread , Isentress , Prezista , Stribild , lamivudine , abacavir , tenofovir , Reyataz , Epzicom , ritonavir , Complera , emtricitabine , darunavir , Kaletra , Intelence , Sustiva , Epivir , efavirenz , nevirapine , atazanavir , raltegravir , Selzentry , More... Emtricitabine / tenofovir alafenamide Rating 1 User Review 1 User Review Not Rated - Be the first! Help and Support Looking for answers? 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