luxurious Sirolimus Tablets Generic Name: Sirolimus Tablets (sir OH li mus) Brand Name: Rapamune Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons Warning This medicine may raise the chance of very bad and sometimes deadly infections. Talk with the doctor. Call your doctor right away if you have any signs of infection like fever, chills, flu-like signs, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or a wound that will not heal. This medicine may raise the chance of getting cancer like lymphoma or skin cancer. Call your doctor right away if you have a change in color or size of a mole, a skin lump or growth, a big weight loss, night sweats, or swollen glands. This medicine is not for use in people who have had liver or lung transplants. Very bad and sometimes deadly problems have happened in these people. Talk with the doctor. Uses of Sirolimus Tablets: It is used to keep the body from turning down the kidney after a kidney transplant. It is used to treat a lung disease called lymphangioleiomyomatosis (LAM). It may be given to you for other reasons. Talk with the doctor. Slideshow Donate Life: What You Need To Know About Organ Donorship What do I need to tell my doctor BEFORE I take Sirolimus Tablets? If you have an allergy to sirolimus or any other part of this medicine (sirolimus tablets). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are taking any of these drugs: Clarithromycin, erythromycin, itraconazole, ketoconazole, rifabutin, rifampin, telithromycin, or voriconazole. If you are breast-feeding or plan to breast-feed. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (sirolimus tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Sirolimus Tablets? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Do not switch between different forms of this medicine (sirolimus tablets) without first talking with the doctor. High blood pressure has happened with this medicine. Have your blood pressure checked as you have been told by your doctor. This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor. Have blood work checked as you have been told by the doctor. Talk with the doctor. Have your urine checked as you have been told by your doctor. If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. Tell your doctor if you get signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit. You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. There is a chance of skin cancer. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. Talk with your doctor before getting any vaccines. Use with this medicine (sirolimus tablets) may either raise the chance of an infection or make the vaccine not work as well. Avoid grapefruit and grapefruit juice. This medicine may affect how wounds heal. Sometimes, people with wound healing problems have needed surgery. Call your doctor right away if you have a wound that is red, warm, painful, or swollen. Call your doctor right away if your wound opens up or if there is blood, fluid, or pus in a wound. Some people treated with this medicine have had very bad kidney problems caused by a certain viral infection (BK virus). In people who have had a kidney transplant, BK virus infection may cause loss of the kidney. Call your doctor right away if you have signs of kidney problems like change in the amount of urine passed, difficulty or pain when passing urine, or blood in the urine. Very bad and sometimes deadly blood problems like thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) have happened with this medicine (sirolimus tablets) in some people. Call your doctor right away if you feel very tired or weak or have any bruising or bleeding; dark urine or yellow skin or eyes; pale skin; change in the amount of urine passed; change in eyesight; change in strength on 1 side is greater than the other, trouble speaking or thinking, or change in balance; or fever. Use birth control that you can trust before care begins, during care, and for 3 months after care ends. If you get pregnant while taking this medicine or within 3 months after your last dose, call your doctor right away. How is this medicine (Sirolimus Tablets) best taken? Use this medicine (sirolimus tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. Always take with food or always take on an empty stomach. To gain the most benefit, do not miss doses. Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well. Do not take cyclosporine capsules (Neoral , Gengraf ) or oral solution (Neoral ) within 4 hours of this medicine (sirolimus tablets). Swallow whole. Do not chew, break, or crush. If you have trouble swallowing, talk with your doctor. What do I do if I miss a dose? Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal. Swelling, warmth, numbness, change of color, or pain in a leg or arm. Chest pain or pressure or a fast heartbeat. Coughing up blood. Feeling very tired or weak. Skin wound that will not heal. Swelling in the arms or legs. Any unexplained bruising or bleeding. Period (menstrual) changes. Very bad and sometimes deadly lung problems have happened with this medicine. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse. A very bad brain problem called progressive multifocal leukoencephalopathy (PML) has happened with this medicine (sirolimus tablets). It may cause disability or can be deadly. Tell your doctor right away if you have signs like confusion, memory problems, low mood (depression), change in the way you act, change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight. Very bad and sometimes deadly liver problems have happened with this medicine. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. What are some other side effects of Sirolimus Tablets? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Belly pain. Hard stools (constipation). Loose stools (diarrhea). Upset stomach. Joint pain. Pimples (acne). Dizziness. Nose or throat irritation. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Sirolimus Tablets? Store at room temperature. Store in a dry place. Do not store in a bathroom. Do not take this medicine (sirolimus tablets) out of the blister pack until you are ready to take it. Take this medicine right away after opening the blister pack. Do not store the removed drug for future use. Protect from light. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (sirolimus tablets) is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine (sirolimus tablets) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine (sirolimus tablets). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about sirolimus Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: mTOR inhibitors Consumer resources Sirolimus Sirolimus Oral Solution Sirolimus (Advanced Reading) Other brands: Rapamune Professional resources Sirolimus (AHFS Monograph) Sirolimus (FDA) Sirolimus (Wolters Kluwer) Related treatment guides Lymphangioleiomyomatosis Organ Transplant, Rejection Prophylaxis} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Sirolimus Rating No Reviews - Be the first! 10 /10 No Reviews - Be the first! 10 Rate it! Manufacturers Dr. Reddy's Laboratories, Inc. Greenstone LLC Zydus Pharmaceuticals (USA) Inc. Drug Class MTOR inhibitors Selective immunosuppressants Related Drugs Lymphangioleiomyomatosis sirolimus , Rapamune , More... Organ Transplant, Rejection Prophylaxis azathioprine , cyclosporine , tacrolimus , CellCept , mycophenolate mofetil , Prograf , Imuran , sirolimus , Rapamune , everolimus , Neoral , Gengraf , More... Sirolimus Images Sirolimus systemic 0.5 mg (1 ) View all images} } individual that
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