most room Sitagliptin and Metformin Extended-Release Tablets Generic Name: Sitagliptin and Metformin Extended-Release Tablets (sit a GLIP tin & met FOR min) Brand Name: Janumet XR Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Warning Rarely, metformin may cause an acid health problem in the blood (lactic acidosis). The risk of lactic acidosis is higher in people with kidney problems and in people who take certain other drugs like topiramate. The risk is also higher in people with liver problems or heart failure, in older people (65 or older), or with alcohol use. If lactic acidosis happens, it can lead to other health problems and can be deadly. Lab tests to check the kidneys may be done while taking this medicine (sitagliptin and metformin extended-release tablets). Talk with the doctor. Call your doctor right away if you have signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast or slow heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps. Do not take this medicine if you have a very bad infection, low oxygen, or a lot of fluid loss (dehydration). If you have liver disease, talk with your doctor. Talk with your doctor before you drink alcohol. If you are having an exam or test with contrast or have had one within the past 48 hours, talk with your doctor. Tell all of your health care providers that you take this medicine (sitagliptin and metformin extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists. Uses of Sitagliptin and Metformin Extended-Release Tablets: It is used to lower blood sugar in patients with high blood sugar (diabetes). Slideshow 14 Essential Health Screenings That All Men Should Consider What do I need to tell my doctor BEFORE I take Sitagliptin and Metformin Extended-Release Tablets? If you have an allergy to sitagliptin, metformin, or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Acidic blood problem, kidney disease, liver disease, or type 1 diabetes. If you have had a recent heart attack or stroke. If you are not able to eat or drink like normal, including before certain procedures or surgery. This is not a list of all drugs or health problems that interact with this medicine (sitagliptin and metformin extended-release tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Sitagliptin and Metformin Extended-Release Tablets? Tell all of your health care providers that you take this medicine (sitagliptin and metformin extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists. Do not drive if your blood sugar has been low. There is a greater chance of you having a crash. Check your blood sugar as you have been told by your doctor. Have blood work checked as you have been told by the doctor. Talk with the doctor. Low blood sugar can happen. The chance of low blood sugar may be raised when this medicine is used with other drugs for high blood sugar (diabetes). Signs may be dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do if you get low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices. It may be harder to control your blood sugar during times of stress like when you have a fever, an infection, an injury, or surgery. A change in level of physical activity or exercise and a change in diet may also affect your blood sugar. Talk with your doctor. Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss. Follow the diet and workout plan that your doctor told you about. If you have been taking this medicine (sitagliptin and metformin extended-release tablets) for a long time or at high doses, it may not work as well and you may need higher doses to get the same effect. This is known as tolerance. Call your doctor if this medicine stops working well. Do not take more than ordered. A skin reaction called bullous pemphigoid has happened with drugs like this one. Sometimes, people have had to go to the hospital. Call your doctor right away if you have blisters or if your skin starts to break down. Heart failure has happened in people taking drugs like this one. Tell your doctor if you have ever had heart failure or kidney problems. Call your doctor right away if you feel very tired or you have shortness of breath, a big weight gain, or swelling in the arms or legs. If you are 65 or older, use this medicine (sitagliptin and metformin extended-release tablets) with care. You could have more side effects. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Sitagliptin and Metformin Extended-Release Tablets) best taken? Use this medicine (sitagliptin and metformin extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with a meal. Take in the evening, unless your doctor tells you otherwise. Swallow whole. Do not chew, break, or crush. Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well. To gain the most benefit, do not miss doses. What do I do if I miss a dose? Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Chest pain or pressure. Fever or chills. Sore throat. Very bad and sometimes deadly pancreas problems (pancreatitis) have happened with this medicine (sitagliptin and metformin extended-release tablets). This could happen at any time during care. Signs of pancreatitis include very bad stomach pain, very bad back pain, or very upset stomach or throwing up. Call your doctor right away if you have any of these signs. It is common to have stomach problems like upset stomach, throwing up, or loose stools (diarrhea) when you start taking this medicine. If you have stomach problems later during care, call your doctor right away. This may be a sign of an acid health problem in the blood (lactic acidosis). A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Drugs like this one may cause joint pain that can be very bad and disabling. Call your doctor right away if you have very bad joint pain or any joint pain that does not go away. You may see something that looks like the tablet in your stool. If you see tablets in your stool a lot, talk with your doctor. What are some other side effects of Sitagliptin and Metformin Extended-Release Tablets? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Belly pain. Upset stomach or throwing up. Loose stools (diarrhea). Gas. Feeling tired or weak. Headache. Sore throat. Stuffy nose. Runny nose. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Sitagliptin and Metformin Extended-Release Tablets? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (sitagliptin and metformin extended-release tablets) is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine (sitagliptin and metformin extended-release tablets) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine (sitagliptin and metformin extended-release tablets). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about metformin/sitagliptin Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 47 Reviews Add your own review/rating Drug class: antidiabetic combinations Consumer resources Metformin and sitagliptin Sitagliptin and Metformin Tablets Sitagliptin and metformin (Advanced Reading) Other brands: Janumet , Janumet XR Professional resources Sitagliptin and Metformin (Wolters Kluwer) Related treatment guides Diabetes, Type 2} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Metformin / sitagliptin Rating 47 User Reviews 6.6 /10 47 User Reviews 6.6 Rate it! Manufacturer Macleods Pharmaceuticals Limited Drug Class Antidiabetic combinations Related Drugs Diabetes, Type 2 metformin , insulin aspart , glipizide , glimepiride , Januvia , pioglitazone , Victoza , Actos , Tradjenta , Glucophage , glyburide , Janumet , Invokana , Amaryl , Welchol , Onglyza , sitagliptin , Trulicity , Jardiance , Lantus , Farxiga , Levemir , Tresiba , Glucotrol , Bydureon , More...} } every body
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