have the option etravirine (Oral route) e-tra-VIR-een Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Intelence Available Dosage Forms: Tablet Therapeutic Class: Antiretroviral Agent Pharmacologic Class: Non-Nucleoside Reverse Transcriptase Inhibitor Slideshow Ladies A Moment: 10 Health Screenings That All Women Need Uses For etravirine Etravirine is used together with other medicines to treat an infection caused by human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). etravirine is usually given to patients who have received HIV treatment in the past. Etravirine will not cure or prevent HIV infection or AIDS; however, it helps keep the HIV virus from reproducing and appears to slow the destruction of the immune system. This may help delay some of the problems related to AIDS or HIV disease. Etravirine will not keep you from spreading HIV to other people. People who take etravirine may continue to have other problems related to AIDS or HIV disease. etravirine is available only with your doctor's prescription. Before Using etravirine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For etravirine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to etravirine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Use of etravirine is not recommended in children younger than 6 years of age. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of etravirine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients using etravirine. Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking etravirine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using etravirine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Dasabuvir Using etravirine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Amiodarone Amprenavir Artemether Atazanavir Avanafil Axitinib Bepridil Bosutinib Carbamazepine Cilostazol Clarithromycin Clopidogrel Cobicistat Cyclosporine Daclatasvir Deflazacort Delavirdine Dexamethasone Diazepam Disopyramide Dolutegravir Donepezil Doxorubicin Doxorubicin Hydrochloride Liposome Efavirenz Elbasvir Enzalutamide Etonogestrel Flecainide Fosamprenavir Fosphenytoin Grazoprevir Ifosfamide Indinavir Ketoconazole Lidocaine Lumefantrine Maraviroc Mexiletine Naloxegol Nelfinavir Nevirapine Nifedipine Orlistat Phenobarbital Phenytoin Piperaquine Posaconazole Propafenone Quinidine Rifabutin Rifampin Rifapentine Rilpivirine Ritonavir Simeprevir Sirolimus St John's Wort Tacrolimus Tipranavir Warfarin Using etravirine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Atorvastatin Boceprevir Clobazam Digoxin Fluconazole Methadone Ospemifene Raltegravir Sildenafil Voriconazole Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of etravirine. Make sure you tell your doctor if you have any other medical problems, especially: Liver disease (including hepatitis B or C) Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of etravirine It is important to take etravirine together with other medicines for HIV. Be sure to take all of the medicines your doctor ordered, and to take them at the right times. If you need help in planning the best times to take your medicine, check with your doctor. It is best to take etravirine following a meal. Swallow the tablet whole with a liquid such as water. Do not chew it. If you or your child cannot swallow the tablet whole, you may dissolve it in a glass with a small amount of water. You may also add more water, orange juice, or milk to make it easier to take. Do not use grapefruit juice, or warm or carbonated drinks. Be sure to drink or swallow the entire mixture right away. Then refill your glass with water, orange juice, or milk and drink it so that none of the medicine is left in the glass. . Keep taking etravirine for the full time of treatment , even if you or your child begin to feel better. Do not change the amount or stop taking etravirine without checking first with your doctor. . etravirine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. . etravirine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor or pharmacist if you have any questions. Dosing The dose of etravirine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of etravirine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For HIV infection: Adults 200 milligrams (mg) two times a day. Children 6 years of age and older weighing at least 16 kg Dose is based on body weight and must be determined by your doctor. The dose is usually 100 to 200 mg two times a day. Children younger than 6 years of age Use is not recommended. Missed Dose If you miss a dose of etravirine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Do not take etravirine if it has been more than 6 hours since you missed your last dose. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using etravirine It is very important that your doctor check the progress of you or your child at regular visits to make sure etravirine is working properly and to check for unwanted effects. When you start taking HIV medicines, your immune system may get stronger. If you have certain infections, such as pneumonia or tuberculosis, you or your child may notice new symptoms when your body tries to fight them. If this occurs, be sure to tell your doctor. Serious skin reactions can occur with etravirine. Stop using etravirine and check with your doctor right away if you or your child have more than one of the following symptoms: blistering, peeling, or loosening of the skin, itching, joint or muscle pain, rash, red skin lesions, sore throat, or sores, ulcers, or white spots in the mouth or on the lips. etravirine may cause you to have excess body fat. Tell your doctor if you or your child notice changes in your body shape, such as an increased amount of fat in the upper back and neck, or around the chest and stomach area; or a loss of fat from the legs, arms, and face. etravirine will not keep you from giving HIV to your partner during sex. Make sure you understand and practice safe sex, even if your partner also has HIV. Do not share needles with anyone. Do not take any other medicines without checking first with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements. To do so may increase the chance of side effects from etravirine. etravirine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Rash Less common Blurred vision burning, numbness, tingling, or painful sensations dizziness headache nervousness pounding in the ears slow or fast heartbeat unsteadiness or awkwardness weakness in the arms, hands, legs, or feet Rare Blistering, peeling, or loosening of the skin chills cough diarrhea fever hives hoarseness irritation itching joint pain, stiffness, or swelling muscle pain red skin lesions, often with a purple center red, irritated eyes redness of the skin shortness of breath sore throat sores, ulcers, or white spots in the mouth or on the lips swelling of the eyelids, face, lips, hands, or feet tightness in the chest trouble with breathing or swallowing unusual tiredness or weakness wheezing Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Nausea Less common Stomach pain vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. 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Next Side Effects Print this page Add to My Med List More about etravirine Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 2 Reviews Add your own review/rating Drug class: NNRTIs Consumer resources Etravirine Other brands: Intelence Professional resources Etravirine (AHFS Monograph) Etravirine (Wolters Kluwer) Related treatment guides HIV Infection} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class NNRTIs Related Drugs HIV Infection Truvada , Atripla , Norvir , Viread , Isentress , Prezista , Stribild , lamivudine , abacavir , tenofovir , Reyataz , Epzicom , ritonavir , Complera , darunavir , emtricitabine , Kaletra , Intelence , Sustiva , Epivir , efavirenz , nevirapine , atazanavir , raltegravir , Selzentry , More... Etravirine Rating 2 User Reviews 7.4 /10 2 User Reviews 7.4 Rate it! 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