you are looking etravirine Generic Name: etravirine (E tra VIR een) Brand Name: Intelence Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A What is etravirine? Etravirine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Etravirine is used with other medicines to treat HIV in adults and children who are at least 6 years old. HIV causes the acquired immunodeficiency syndrome (AIDS). Etravirine is not a cure for HIV or AIDS. Etravirine may also be used for purposes not listed in this medication guide. Slideshow Ladies A Moment: 10 Health Screenings That All Women Need What is the most important information I should know about etravirine? In rare cases, etravirine can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Etravirine must be taken in combination with other HIV medications. However, some drugs can raise or lower your blood levels of etravirine. Etravirine can also affect blood levels of certain other drugs. This can make your medicines less effective or increase side effects. TELL YOUR DOCTOR ABOUT ALL OTHER MEDICINES YOU USE. What should I discuss with my healthcare provider before taking etravirine? You should not take etravirine if you are allergic to it. To make sure you can safely take etravirine, tell your doctor if you have any liver disease, including hepatitis B or C. Etravirine must be taken in combination with other HIV medications. However, there are certain combinations of medicines that should not be used together with etravirine. Follow your doctor's dosing instructions very carefully. You SHOULD NOT take etravirine together with: delavirdine; efavirenz; nevirapine; rifabutin, rifapentine, rifampin; rilpivirine; St. John's wort; ritonavir when given with fosamprenavir or tipranavir; ritonavir in doses of more than 600 milligrams twice daily; or seizure medications--carbamazepine, phenytoin, phenobarbital. You MUST take etravirine together with ritonavir if you are also taking a protease inhibitor, such as atazanavir, dolutegravir, fosamprenavir, indinavir, or nelfinavir. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection. Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk. How should I take etravirine? Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Etravirine must be taken in combination with other HIV medications. Follow your doctor's dosing instructions very carefully. If a child is taking this medication, tell your doctor if the child has any changes in weight. Etravirine doses are based on weight in children. Etravirine works best if you take it after a meal. Do not take it on an empty stomach. Do not crush, chew, or break an etravirine tablet. Swallow it whole with liquid such as water. If you cannot swallow an etravirine tablet whole, place it into a glass of water and allow the tablet to disperse in the liquid. The tablet will not dissolve completely. Drink this mixture right away. To make sure you get the entire dose, add a little more liquid to the same glass, swirl gently and drink right away. While using etravirine, you may need frequent blood tests at your doctor's office. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor. Store at room temperature away from moisture and heat. Keep the tablets in their original container. What happens if I miss a dose? If you are less than 6 hours late in taking your medicine, take the missed dose after your next meal. Then return to your regular dosing schedule. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking etravirine? Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person. Etravirine side effects Get emergency medical help if you have any of these signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. In rare cases, etravirine can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Stop using etravirine and call your doctor at once if you have: swelling, rapid weight gain, little or no urinating; confusion, seizure; liver problems--nausea, upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); the first sign of any type of skin rash, no matter how mild; or severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Etravirine may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with etravirine. Tell your doctor if you have: signs of a new infection--fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss; chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath; cold sores, sores on your genital or anal area; rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement; trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex. Common side effects may include: diarrhea; numbness or tingly feeling in your hands or feet; rash; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Etravirine dosing information Usual Adult Dose for HIV Infection: 200 mg orally twice a day after a meal Usual Pediatric Dose for HIV Infection: 6 to less than 18 years: 16 kg to less than 20 kg: 100 mg orally twice a day after a meal 20 kg to less than 25 kg: 125 mg orally twice a day after a meal 25 kg to less than 30 kg: 150 mg orally twice a day after a meal 30 kg or more: 200 mg orally twice a day after a meal What other drugs will affect etravirine? Some drugs can raise or lower your blood levels of etravirine, which may cause side effects or make etravirine less effective. Etravirine can also affect blood levels of certain other drugs, making them less effective or increasing side effects. Many drugs can interact with etravirine. Not all possible interactions are listed here. TELL YOUR DOCTOR ABOUT ALL OTHER MEDICINES YOU USE, and any you start or stop using during treatment with etravirine, especially: artemether and lumefantrine; boceprevir or telaprevir; clarithromycin; clopidogrel; dexamethasone; diazepam (Valium); maraviroc; an antifungal medicine--itraconazole, ketoconazole, posaconazole; a blood thinner--warfarin, Coumadin; cholesterol lowering medicine--atorvastatin, fluvastatin, lovastatin, pitavastatin, simvastatin; heart rhythm medicine--amiodarone, digoxin, disopyramide, flecainide, mexiletine, propafenone, quinidine; medicine for erectile dysfunction or pulmonary arterial hypertension--sildenafil, tadalafil, vardenafil; medicines to prevent organ transplant rejection--cyclosporine, sirolimus, tacrolimus; or narcotic medication--buprenorphine, methadone. This list is not complete. Other drugs may interact with etravirine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Next Side Effects Print this page Add to My Med List More about etravirine Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 2 Reviews Add your own review/rating Drug class: NNRTIs Consumer resources Etravirine Etravirine (Advanced Reading) Other brands: Intelence Professional resources Etravirine (AHFS Monograph) Etravirine (Wolters Kluwer) Related treatment guides HIV Infection Where can I get more information? Your pharmacist can provide more information about etravirine. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 11.04. Date modified: December 03, 2017 Last reviewed: April 20, 2017} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class NNRTIs Related Drugs HIV Infection Truvada , Atripla , Norvir , Viread , Isentress , Prezista , Stribild , lamivudine , abacavir , tenofovir , Epzicom , Reyataz , ritonavir , Complera , emtricitabine , darunavir , Kaletra , Intelence , Sustiva , Epivir , efavirenz , nevirapine , atazanavir , raltegravir , Selzentry , More... Etravirine Rating 2 User Reviews 7.4 /10 2 User Reviews 7.4 Rate it! Help and Support Looking for answers? Ask a question or go join the etravirine support group to connect with others who have similar interests.} } training session
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