for example Carbaglu (Oral) Generic Name: carglumic acid (Oral route) kar-GLOO-mik AS-id Overview Side Effects Dosage Professional Pregnancy More User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Carbaglu Available Dosage Forms: Tablet Slideshow Treatment of Opioid-Induced Constipation: The Hard Facts Uses For Carbaglu Carglumic acid is used together with diet and other medicines to treat and prevent hyperammonemia (too much ammonia in the blood) when it is caused by the lack of a liver enzyme called N-acetylglutamate synthase (NAGS). Ammonia is formed in the body when we digest protein. A person without the NAGS enzyme can not process ammonia properly, and too much ammonia will collect in the blood. This will cause serious unwanted effects. Carglumic acid acts by replacing the NAGS enzyme and helps reduce the amount of ammonia in the blood. This medicine is available only with your doctor's prescription. Before Using Carbaglu In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of carglumic acid in children. Geriatric Appropriate studies have not been performed on the relationship of age to the effects of carglumic acid in the geriatric population. Safety and efficacy have not been established. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Proper Use of Carbaglu Take this medicine exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. It is important that you and your child follow any special diet instructions from your doctor, such as using a low-protein diet. If you have any questions about this, check with your doctor. Do not swallow the tablet whole. Do not break, crush, or chew it. Also, it is best to take this medicine on an empty stomach, unless your doctor tells you otherwise. To use : Dissolve the tablet in a small container or medicine cup with at least 2.5 milliliters (one-half teaspoonful) of water. Shake the container gently to dissolve the tablet. Drink the mixture right away. Some small particles or specks may be left at the bottom of the container. Rinse the mixing container with water and drink the water right away to make sure you take all of the medicine. To use with a nasogastric tube (NGT) : Dissolve the tablet in a small container or medicine cup with at least 2.5 milliliters (one-half teaspoonful) of water. Shake the container gently to dissolve the tablet. Pour the mixture into the tube right away. Some small particles or specks may be left at the bottom of the container or in the tubing. Rinse the mixing container with water and pour the water into the tube right away. This will clear the particles from the tube and make sure you have given all of the medicine. To use with an oral syringe : Dissolve the tablet in a small container or medicine cup with at least 2.5 milliliters (mL) or one-half teaspoonful of water. Shake the container gently to dissolve the tablet. Use an oral syringe to measure the correct amount of mixture for the dose and give it right away. Throw away any unused medicine in the container. Some small particles or specks may be left in the oral syringe. Refill the oral syringe with 1 to 2 mL of water and give the water right away. This will clear the particles from the syringe and make sure you have given all of the medicine. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For hyperammonemia: Adults and teenagers Dose is based on body weight and must be determined by your doctor. The starting dose is 100 to 250 milligrams (mg) per kilogram (kg) of body weight per day. The total dose will be divided and given in 2 to 4 doses per day. Children Dose is based on body weight and must be determined by your child's doctor. The starting dose is 100 to 250 milligrams (mg) per kilogram (kg) of body weight per day. The total dose will be divided and given in 2 to 4 doses per day. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Before you open the bottle , store it in the refrigerator. Do not freeze. After you open the bottle for the first time, store it at room temperature. Keep the bottle tightly closed, and away from heat, moisture, and direct light. Do not refrigerate the bottle. Write the date you used the first tablet on the bottle. Throw away any unused medicine 30 days after the date on the bottle. Precautions While Using Carbaglu It is very important that your doctor check the progress of you or your child at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects. Hyperammonemia (too much ammonia in the blood) is a life-threatening condition that requires immediate medical attention. Check with your doctor right away if you or your child have any of the following symptoms: nausea or vomiting that continues, an increase in the frequency of seizures, a loss of appetite, swelling of the face, tiredness and weakness, or yellow eyes or skin. Carbaglu Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Chills cough or hoarseness decreased weight diarrhea fever or chills general feeling of discomfort or illness headache increased sweating joint pain loss of appetite lower back or side pain muscle aches and pains nausea painful or difficult urination pale skin runny nose shivering sore throat sweating trouble sleeping troubled breathing with exertion unusual bleeding or bruising unusual tiredness or weakness vomiting Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Fast, pounding, or irregular heartbeat or pulse increase in mucous from the lungs restlessness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain change in hearing change in taste congestion ear drainage earache or pain in the ear lack or loss of strength loss of taste rash sleepiness or unusual drowsiness stuffy or runny nose swollen glands Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Carbaglu (carglumic acid) Side Effects During Pregnancy Dosage Information Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: miscellaneous uncategorized agents Consumer resources Carbaglu Professional resources Carbaglu (AHFS Monograph) Carbaglu (FDA) Related treatment guides Hyperammonemia} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug 7 years Approval History FDA approved 2010 Drug Class Miscellaneous uncategorized agents Related Drugs Hyperammonemia sodium benzoate / sodium phenylacetate , carglumic acid , More... Carbaglu Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Related Questions & Answers Anyone know of a way to pay for Carbaglu? My son has medicaid of KY? Read more questions} } contemplating
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