quickens Rezira (Oral) Generic Name: hydrocodone and pseudoephedrine (Oral route) hye-droe-KOE-done bye-TAR-trate, soo-doe-e-FED-rin hye-droe-KLOR-ide Oral route(Solution) Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Avoid use of opioid cough medications in patients taking benzodiazepines, other CNS depressants, or alcohol . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Pancof HC Rezira Available Dosage Forms: Solution Liquid Syrup Tablet Therapeutic Class: Antitussive, Opioid/Decongestant Combination Pharmacologic Class: Pseudoephedrine Chemical Class: Hydrocodone Slideshow Seasoned Pro: Be Mindful of These Winter Health Hazards Uses For Rezira Hydrocodone and pseudoephedrine combination is used in adults to relieve cough and nasal congestion (stuffy nose) caused by the common cold. Hydrocodone is a narcotic antitussive (cough suppressant). It acts directly on the cough center in the brain to relieve cough. Pseudoephedrine is a decongestant, which decreases nasal congestion by narrowing the blood vessels and reducing blood flow to the nasal passage. When hydrocodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing cough and nasal congestion should not let the fear of dependence keep them from using narcotics to relieve their cough. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. This medicine is available only with your doctor's prescription. Before Using Rezira In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Use of hydrocodone and pseudoephedrine combination is not indicated in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydrocodone and pseudoephedrine combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving this medicine. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Dihydroergotamine Furazolidone Iproniazid Isocarboxazid Linezolid Methylene Blue Moclobemide Nalmefene Naltrexone Nialamide Phenelzine Procarbazine Rasagiline Safinamide Selegiline Tranylcypromine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acepromazine Alfentanil Almotriptan Alprazolam Amineptine Amisulpride Amitriptyline Amitriptylinoxide Amobarbital Amoxapine Amphetamine Anileridine Aprepitant Aripiprazole Asenapine Atazanavir Baclofen Benperidol Benzphetamine Boceprevir Bromazepam Bromopride Brompheniramine Buprenorphine Buspirone Butabarbital Butorphanol Carbinoxamine Carisoprodol Carphenazine Ceritinib Chloral Hydrate Chlordiazepoxide Chlorpheniramine Chlorpromazine Chlorzoxazone Citalopram Clarithromycin Clobazam Clomipramine Clonazepam Clorazepate Clozapine Cocaine Codeine Conivaptan Cyclobenzaprine Dasabuvir Desipramine Desmopressin Desvenlafaxine Dexmedetomidine Dextroamphetamine Dextromethorphan Dezocine Diazepam Dibenzepin Dichloralphenazone Difenoxin Dihydrocodeine Diltiazem Diphenhydramine Diphenoxylate Dolasetron Donepezil Doxepin Doxylamine Dronedarone Droperidol Duloxetine Eletriptan Enflurane Erythromycin Escitalopram Estazolam Eszopiclone Ethchlorvynol Ethopropazine Ethylmorphine Fentanyl Flibanserin Fluconazole Fluoxetine Fluphenazine Flurazepam Fluspirilene Fluvoxamine Fosaprepitant Fospropofol Frovatriptan Furazolidone Granisetron Guanethidine Halazepam Haloperidol Halothane Hexobarbital Hydromorphone Hydroxytryptophan Hydroxyzine Idelalisib Imatinib Imipramine Indinavir Iobenguane I 123 Iproniazid Isocarboxazid Isoflurane Itraconazole Ketamine Ketazolam Ketobemidone Ketoconazole Levomilnacipran Levorphanol Linezolid Lisdexamfetamine Lithium Lofepramine Lopinavir Lorazepam Lorcaserin Loxapine Meclizine Melitracen Melperone Meperidine Mephobarbital Meprobamate Meptazinol Mesoridazine Metaxalone Methadone Methamphetamine Methdilazine Methocarbamol Methohexital Methotrimeprazine Methyldopa Methylene Blue Midazolam Midodrine Milnacipran Mirtazapine Moclobemide Molindone Moricizine Morphine Morphine Sulfate Liposome Nalbuphine Naratriptan Nefazodone Nelfinavir Netupitant Nialamide Nicomorphine Nitrazepam Nitrous Oxide Nortriptyline Olanzapine Ombitasvir Ondansetron Opipramol Opium Opium Alkaloids Orphenadrine Oxazepam Oxycodone Oxymorphone Palonosetron Papaveretum Paregoric Paritaprevir Paroxetine Pentazocine Pentobarbital Perampanel Perazine Periciazine Perphenazine Phenelzine Phenobarbital Piperacetazine Pipotiazine Piritramide Posaconazole Prazepam Primidone Procarbazine Prochlorperazine Promazine Promethazine Propofol Protriptyline Quazepam Quetiapine Ramelteon Rasagiline Remifentanil Remoxipride Ritonavir Rizatriptan Saquinavir Secobarbital Selegiline Sertindole Sertraline Sibutramine Sodium Oxybate Sufentanil Sulpiride Sumatriptan Suvorexant Tapentadol Telaprevir Telithromycin Temazepam Thiethylperazine Thiopental Thiopropazate Thioridazine Tianeptine Tilidine Tizanidine Tolonium Chloride Topiramate Tramadol Tranylcypromine Trazodone Triazolam Trifluoperazine Trifluperidol Triflupromazine Trimeprazine Trimipramine Tryptophan Venlafaxine Verapamil Vilazodone Voriconazole Vortioxetine Zaleplon Ziprasidone Zolmitriptan Zolpidem Zopiclone Zotepine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Grapefruit Juice Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Addison's disease (adrenal gland problem) or Asthma or Diabetes or Drug dependence, especially narcotic abuse or dependence, or history of or Enlarged prostate (BPH, prostatic hypertrophy) or Head injury, history of or Problems with passing urine or Stomach or bowel problems (eg, paralytic ileus) or Thyroid disease Use with caution. May increase risk for more serious side effects. Heart disease (eg, coronary artery disease), severe or Hypertension (high blood pressure), severe or Narrow angle glaucoma or Urinary retention Should not be used in patients with these conditions. Kidney disease, severe or Liver disease, severe Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of hydrocodone and pseudoephedrine This section provides information on the proper use of a number of products that contain hydrocodone and pseudoephedrine. It may not be specific to Rezira. Please read with care. Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose. This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions. Measure the oral liquid correctly using the marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Ask your pharmacist for instructions for measuring the correct dose of this medicine. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (solution): For relief of cough and nasal congestion: Adults 5 milliliters (mL) every 4 to 6 hours as needed. However, the dose is usually not more than 4 doses (20 mL) in 24 hours. Children Use is not recommended. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Rezira It is very important that your doctor check your progress while you are using this medicine . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms do not improve or if they get worse, call your doctor. Do not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl , Marplan , Nardil , or Parnate within the past 14 days. Symptoms of an overdose include: extreme dizziness or weakness, trouble breathing, slow heartbeat or breathing, seizures, and cold, clammy skin. In case of an overdose, call your doctor right away. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose . Call your doctor for instructions. This medicine may make you dizzy or drowsy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine . Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. Using this medicine while you are pregnant may cause neonatal withdrawal syndrome in your newborn babies. Tell your doctor right away if your child has the following symptoms: abnormal sleep pattern, diarrhea, fever, high-pitched cry, irritability, shakiness or tremor, vomiting, weight loss, or failure to gain weight. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Rezira Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Blurred vision confusion dizziness dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fainting fast, slow, or irregular heartbeat sweating unusual tiredness or weakness Incidence not known Abdominal or stomach cramps or pain bloating bulging soft spot on the head of an infant change in the ability to see colors, especially blue or yellow convulsions decrease in the frequency of urination decrease in urine volume diarrhea difficult or painful urination difficult or troubled breathing difficulty having a bowel movement (stool) difficulty in passing urine (dribbling) drowsiness frequent urge to urinate headache irregular, fast or slow, or shallow breathing loss of appetite nervousness pale or blue lips, fingernails, or skin pounding in the ears shakiness in the legs, arms, hands, or feet trembling or shaking of the hands or feet trouble with sleeping vomiting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Fear mood changes nausea relaxed and calm sleepiness unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness Incidence not known Itching or skin rash weakness Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. 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Next Side Effects Print this page Add to My Med List More about Rezira (hydrocodone / pseudoephedrine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons 6 Reviews Add your own review/rating Generic Availability Drug class: upper respiratory combinations Consumer resources Rezira Other brands: Pancof HC Professional resources Rezira (FDA) Related treatment guides Cough and Nasal Congestion} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out 2 CSA Schedule High potential for abuse Approval History Drug history at FDA WADA Class Anti-Doping Classification Drug Class Upper respiratory combinations Related Drugs Cough and Nasal Congestion Promethazine VC with Codeine , Bromfed DM , Mucinex D , Vanacof , Deconex , codeine / phenylephrine / promethazine , Vicks NyQuil Severe Cold & Flu , Resperal-DM , Vicks Nyquil Cough , Coricidin HBP Cough & Cold , Deconex DMX , Crantex , Robitussin Allergy & Cough , Tussin CF , Relasin-HC , Mucinex Fast-Max Severe Congestion & Cough , Dimetapp Children's Cold & Cough , Robitussin Nighttime Cough DM , More... Rezira Rating 6 User Reviews 8.8 /10 6 User Reviews 8.8 Rate it! Help and Support Looking for answers? Ask a question or go join the Rezira support group to connect with others who have similar interests.} } remedies
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