bring together Evotaz (Oral) Generic Name: atazanavir and cobicistat (Oral route) a-ta-ZAN-a-vir, koe-BIK-i-stat Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Evotaz Available Dosage Forms: Tablet Therapeutic Class: Antiretroviral Agent Pharmacologic Class: Protease Inhibitor Slideshow Save Your Blushes - The FAQ's On STDs Uses For Evotaz Atazanavir and cobicistat combination is used together with other medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Atazanavir and cobicistat combination will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. This medicine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease. This medicine is available only with your doctor's prescription. Before Using Evotaz In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of atazanavir and cobicistat combination in the pediatric population. Safety and efficacy have not been established. Use is not recommended in children younger than 3 months of age because atazanavir may cause kernicterus. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of atazanavir and cobicistat combination in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution for patients receiving this medicine. Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Alfuzosin Amifampridine Amisulpride Bepridil Carbamazepine Cisapride Colchicine Conivaptan Crizotinib Dihydroergotamine Doxorubicin Doxorubicin Hydrochloride Liposome Dronedarone Eletriptan Eliglustat Enzalutamide Eplerenone Ergoloid Mesylates Ergonovine Ergotamine Flibanserin Fluconazole Fosphenytoin Grazoprevir Indinavir Irinotecan Irinotecan Liposome Isavuconazonium Sulfate Ivabradine Ketoconazole Lomitapide Lovastatin Lurasidone Maraviroc Mesoridazine Methylergonovine Methysergide Midazolam Mitotane Naloxegol Nelfinavir Nevirapine Pazopanib Phenobarbital Phenytoin Pimozide Piperaquine Primidone Ranolazine Rifampin Riociguat Romidepsin Saquinavir Sildenafil Silodosin Simvastatin Sparfloxacin St John's Wort Terfenadine Thioridazine Tolvaptan Triazolam Venetoclax Vinflunine Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Ado-Trastuzumab Emtansine Afatinib Alprazolam Amiodarone Amitriptyline Amlodipine Amprenavir Anagrelide Apixaban Aprepitant Aripiprazole Arsenic Trioxide Artemether Atorvastatin Avanafil Axitinib Bedaquiline Betrixaban Boceprevir Bosentan Bosutinib Brentuximab Vedotin Brexpiprazole Brigatinib Bromocriptine Budesonide Buprenorphine Buserelin Cabazitaxel Cabozantinib Calcifediol Cariprazine Ceritinib Cilostazol Cimetidine Clarithromycin Clomipramine Clozapine Cobimetinib Cyclophosphamide Cyclosporine Dabrafenib Daclatasvir Darunavir Dasabuvir Dasatinib Deflazacort Degarelix Delamanid Delavirdine Deslorelin Deutetrabenazine Dexamethasone Dexlansoprazole Diazepam Digoxin Diltiazem Disopyramide Docetaxel Domperidone Donepezil Efavirenz Eluxadoline Eplerenone Erlotinib Erythromycin Escitalopram Eslicarbazepine Acetate Esomeprazole Eszopiclone Etravirine Everolimus Famotidine Felodipine Fentanyl Flecainide Fluoxetine Fluticasone Fluvastatin Fosamprenavir Fosaprepitant Foscarnet Garlic Gonadorelin Goserelin Haloperidol Histrelin Hydrocodone Hydrocortisone Hydroxychloroquine Hydroxyzine Ibrutinib Idelalisib Ifosfamide Iloperidone Imipramine Irinotecan Irinotecan Liposome Itraconazole Ivabradine Ivacaftor Ixabepilone Ketoconazole Lacosamide Lamotrigine Lansoprazole Lapatinib Leuprolide Levofloxacin Levomilnacipran Lidocaine Lofepramine Lopinavir Lumefantrine Lurasidone Macitentan Manidipine Methadone Metronidazole Mexiletine Midostaurin Mifepristone Minocycline Morphine Morphine Sulfate Liposome Moxifloxacin Nafarelin Netupitant Nevirapine Nicardipine Nifedipine Nilotinib Nimodipine Nisoldipine Nizatidine Olaparib Omeprazole Ondansetron Orlistat Oxcarbazepine Oxycodone Palbociclib Panobinostat Pantoprazole Paritaprevir Pasireotide Pimavanserin Piperaquine Pitolisant Pixantrone Ponatinib Pravastatin Propafenone Quetiapine Quinidine Rabeprazole Ranitidine Reboxetine Regorafenib Repaglinide Retapamulin Ribociclib Rifabutin Rifapentine Ritonavir Rivaroxaban Rosuvastatin Ruxolitinib Salmeterol Saquinavir Sevoflurane Simeprevir Sirolimus Sonidegib Sulpiride Sunitinib Suvorexant Tacrolimus Tadalafil Tamoxifen Tamsulosin Telithromycin Temsirolimus Tenofovir Disoproxil Fumarate Thiotepa Ticagrelor Tipranavir Tolvaptan Topotecan Toremifene Trabectedin Tramadol Trazodone Trimipramine Triptorelin Valbenazine Vandetanib Vardenafil Vemurafenib Venetoclax Venlafaxine Verapamil Vilanterol Vilazodone Vinblastine Vincristine Vincristine Sulfate Liposome Vinflunine Vorapaxar Voriconazole Warfarin Zolpidem Zuclopenthixol Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aripiprazole Lauroxil Atazanavir Cobicistat Dapsone Darunavir Desogestrel Didanosine Dienogest Drospirenone Estradiol Cypionate Estradiol Valerate Ethinyl Estradiol Ethynodiol Diacetate Etonogestrel Indinavir Levonorgestrel Lopinavir Medroxyprogesterone Acetate Mestranol Methadone Nelfinavir Norelgestromin Norethindrone Norgestimate Norgestrel Suvorexant Telaprevir Trazodone Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Diabetes or Fanconi syndrome (kidney disease), history of or Gallbladder problems or Hemophilia (a bleeding problem) or Hyperglycemia (high blood sugar) or Kidney failure, history of or Liver disease (eg, hepatitis B or C) Use with caution. May make these conditions worse. Heart block or Heart conduction problems (eg, prolonged PR interval) May change the way your heart beats and increase your chance of getting side effects. Kidney disease, severe Use is not recommended in these patients. Proper Use of Evotaz Take this medicine exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information. You should talk to your doctor if you have any questions. Do not change the dose or stop using this medicine without checking first with your doctor . When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine. If you are also using antacids or didanosine (Videx ), take atazanavir 2 hours before or 1 hour after taking these medicines. Atazanavir and cobicistat contains a fixed amount of medicine in each tablet. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For treatment of HIV infection: Adults One tablet once a day with food. Each tablet contains 300 milligrams (mg) of atazanavir and 150 mg of cobicistat. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Do not take this medicine if it has been more than 12 hours since you missed your last dose. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Evotaz Your doctor will want to check your progress at regular visits , especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for any unwanted effects. This medicine should not be used together with alfuzosin (Uroxatral ), carbamazepine (Tegretol ), cisapride (Propulsid ), colchicine (Colcrys ), dronedarone (Multaq ), elbasvir/grazoprevir (Zepatier ), indinavir (Crixivan ), irinotecan (Camptosar ), lovastatin (Mevacor ), lurasidone (Latuda ), midazolam (Versed ), nevirapine (Viramune ), phenobarbital (Luminal ), phenytoin (Dilantin ), pimozide (Orap ), ranolazine (Ranexa ), rifampin (Rifadin , Rimactane ), sildenafil (Revatio ), simvastatin (Zocor ), St John's wort, triazolam (Halcion ), or ergot medicines (such as dihydroergotamine, ergotamine, methylergonovine, Cafergot , Ergomar , Wigraine ). This medicine may cause heart rhythm problems (eg, PR prolongation). Tell your doctor right away if you get dizzy or lightheaded. Serious allergic and skin reactions can occur with this medicine. Check with your doctor right away if you have any of the following symptoms while using this medicine: severe rash, blistering, peeling, or loose skin, chills, cough, diarrhea, itching, joint or muscle pain, red skin lesions, often with a purple center, skin rash, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness. This medicine may increase your risk of having kidney stones or gallstones. Check with your doctor right away if you have blood in your urine, nausea and vomiting, pain in the groin or genitals, or sharp back pain just below the ribs, stomach fullness or pain, recurrent fever, or yellow eyes or skin. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem. Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis. Autoimmune disorders (such as Graves' disease, polymyositis, and Guillain-Barré syndrome) may also occur. This medicine may increase blood sugar levels. Check with your doctor if you notice a change in the results of your blood or urine sugar tests. This medicine does not decrease the risk of transmitting the HIV infection to others through sexual contact or by contaminated blood. Make sure you understand and practice safe sex, even if your partner also has HIV. Avoid sharing needles with anyone. This medicine may cause you to have excess body fat. Tell your doctor if you notice changes in your body shape, such as an increased amount of fat in the upper back and neck, or around the chest and stomach area. You might also lose fat from the legs, arms, and face. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or non-prescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Evotaz Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Abdominal or stomach pain chills clay-colored stools dark urine dizziness fever headache itching or rash loss of appetite nausea unpleasant breath odor unusual tiredness or weakness vomiting of blood yellow eyes or skin Incidence not known Abdominal or stomach fullness or tenderness black, tarry stools blistering, peeling, or loosening of the skin blood in the urine chest pain clay colored stools decreased appetite diarrhea gaseous abdominal or stomach pain joint or muscle pain pain in the groin or genitals painful or difficult urination recurrent fever red skin lesions, often with a purple center red, irritated eyes sharp back pain just below the ribs sore throat sores, ulcers, or white spots in the mouth or on the lips swelling of the feet or lower legs swollen glands unusual bleeding or bruising Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about Evotaz (atazanavir / cobicistat) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: antiviral combinations Consumer resources Evotaz Professional resources Evotaz (FDA) Related treatment guides HIV Infection} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer Bristol-Myers Squibb Company Drug Class Antiviral combinations Related Drugs HIV Infection Truvada , Atripla , Norvir , Viread , Isentress , Prezista , Stribild , lamivudine , abacavir , tenofovir , Reyataz , Epzicom , ritonavir , Complera , emtricitabine , darunavir , Kaletra , Intelence , Sustiva , Epivir , efavirenz , nevirapine , atazanavir , raltegravir , Selzentry , More... Evotaz Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Evotaz Images Evotaz atazanavir 300 mg / cobicistat 150 mg (3641 ) View larger images Help and Support Looking for answers? Ask a question or go join the Evotaz support group to connect with others who have similar interests.} } courteously
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