music [25:800 mg daily. 1 2 Cautions for Sectral Contraindications Patients with heart block greater than first degree, severe bradycardia, cardiogenic shock, or overt cardiac failure. 1 Warnings/Precautions Warnings Heart Failure Possible precipitation of heart failure. 1 Avoid use in patients with decompensated heart failure; use cautiously in patients with inadequate myocardial function and, if necessary, in patients with well-compensated heart failure (e.g., those controlled with cardiac glycosides and/or diuretics). 1 Adequate treatment (e.g., with a cardiac glycoside and/or diuretic) and close observation recommended if signs or symptoms of impending cardiac failure occur; if cardiac failure continues, discontinue therapy, gradually if possible. 1 Abrupt Withdrawal of Therapy Possible exacerbated angina symptoms or precipitation of MI in patients with CAD. 1 Abrupt discontinuance of therapy is not recommended. 1 276 Gradually decrease dosage over a period of about 2 weeks; monitor patients carefully and advise to temporarily limit their physical activity. 1 276 If exacerbation of angina occurs, reinstitute therapy promptly and initiate appropriate measures for the management of unstable angina pectoris. 1 Peripheral Vascular Disease Possible reduction in cardiac output and precipitation or aggravation of symptoms of arterial insufficiency. 1 Use with caution; observe for evidence of disease progression. 1 Bronchospastic Disease Possible bronchoconstriction. 1 Use with caution in patients with bronchospastic disease; administer the lowest effective dosage (initially in divided doses). A bronchodilator (e.g., a β 2 -adrenergic agonist, theophylline) should be available for immediate use, if necessary. 1 Major Surgery Possible risks associated with general anesthesia (e.g., severe hypotension, maintenance of heart beat) due to decreased ability of the heart to respond to reflex β-adrenergic stimuli. 1 Use with caution in patients undergoing major surgery involving general anesthesia; anesthetics used should not cause myocardial depression. 1 Diabetes and Hypoglycemia Possible decreased signs and symptoms of hypoglycemia (e.g., tachycardia, palpitation, BP changes, tremor, feelings of anxiety, but not sweating or dizziness) and increased insulin-induced hypoglycemia. 1 Use with caution in patients with diabetes mellitus. 1 Thyrotoxicosis Signs of hyperthyroidism (e.g., tachycardia) may be masked. 1 Possible thyroid storm if therapy is abruptly withdrawn; carefully monitor patients having or suspected of developing thyrotoxicosis. 1 Sensitivity Reactions Anaphylactic Reactions Patients with a history of anaphylactic reactions to a variety of allergens may be more reactive to repeated accidental, diagnostic, or therapeutic challenges with such allergens while taking β-blocking agents. 1 Such patients may be unresponsive to usual doses of epinephrine. 1 Specific Populations Pregnancy Category B. 1 Lactation Distributed into milk in higher concentrations than in maternal plasma. 1 2 105 Use not recommended by manufacturer. 1 Pediatric Use Safety and efficacy not established in children] FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug 10 + years Approval History FDA approved 1984 WADA Class Anti-Doping Classification Drug Class Cardioselective beta blockers Group II antiarrhythmics Related Drugs High Blood Pressure amlodipine , lisinopril , hydrochlorothiazide , furosemide , losartan , metoprolol , atenolol , More... Premature Ventricular Depolarizations bisoprolol , Zebeta , acebutolol , More... Ventricular Arrhythmia sotalol , magnesium sulfate , acebutolol , Betapace , Epsom Salt , Sorine , More... Sectral Rating 2 User Reviews 9.5 /10 2 User Reviews 9.5 Rate it! Sectral Images Sectral 200 MG (SECTRAL 200 WYETH 4177) View all images present day
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