one way cariprazine (Oral route) kar-IP-ra-zeen Oral route(Capsule) Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Cariprazine is not approved for the treatment of patients with dementia-related psychosis . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Vraylar Available Dosage Forms: Capsule Therapeutic Class: Antipsychotic Slideshow A Friend In Need: Getting Smart With Mental Illness Uses For cariprazine Cariprazine is used to treat symptoms of psychotic (mental) disorders, such as schizophrenia, mania, or bipolar disorder. cariprazine should not be used to treat behavioral problems in older adults with dementia. It changes some of the chemicals in the brain that cause psychotic disorders. cariprazine is available only with your doctor's prescription. Before Using cariprazine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cariprazine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to cariprazine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of cariprazine in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies on the relationship of age to the effects of cariprazine have not been performed in the geriatric population, but geriatric-specific problems are not expected to limit the usefulness of cariprazine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving cariprazine. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking cariprazine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using cariprazine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Bromopride Using cariprazine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Boceprevir Carbamazepine Clarithromycin Cobicistat Conivaptan Fentanyl Fosphenytoin Idelalisib Indinavir Itraconazole Ketoconazole Lopinavir Nefazodone Nelfinavir Phenytoin Posaconazole Remifentanil Rifampin Ritonavir Saquinavir St John's Wort Telaprevir Telithromycin Voriconazole Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of cariprazine. Make sure you tell your doctor if you have any other medical problems, especially: Blood vessel or circulation problems or Dehydration or Heart attack, history of or Heart disease or Heart failure or Heart rhythm problems or Hypovolemia (low amount of blood) or Stroke, history of May cause side effects to become worse. Diabetes or Hyperglycemia (high blood sugar) or Hypotension (low blood pressure) or Leukopenia (low white blood cells) or Neuroleptic malignant syndrome (NMS), history of or Seizures, history of or Tardive dyskinesia (movement disorder), history of or Trouble with swallowing Use with caution. May make these conditions worse. Proper Use of cariprazine Take cariprazine exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. You may take cariprazine with or without food. Dosing The dose of cariprazine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of cariprazine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (capsules): For bipolar disorder and schizophrenia: Adults At first, 1.5 milligrams (mg) once a day. Your doctor will adjust your dose as needed. However, the dose is usually not more than 6 mg per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of cariprazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using cariprazine It is very important that your doctor check your progress at regular visits to make sure cariprazine is working properly. Blood tests may be needed to check for unwanted effects. Check with your doctor right away if you have convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS). cariprazine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs. For diabetic patients : cariprazine may cause high blood sugar levels (hyperglycemia). Check with your doctor right away if you have increased thirst or increased urination. If you notice a change in the results of your urine or blood sugar tests, or if you have any questions, check with your doctor. cariprazine may increase your weight. Your doctor may need to check your weight on a regular basis while you are using cariprazine. Talk to your doctor about ways to prevent weight gain. Cariprazine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor. cariprazine may cause dizziness, drowsiness, trouble with thinking, or trouble with controlling body movements. Make sure you know how you react to cariprazine before you drive, use machines, or do anything else that requires you to be alert, well-coordinated, or able to think clearly . cariprazine might reduce how much you sweat and make you feel too hot. You might feel dizzy, weak, tired, or confused, or begin to vomit or have an upset stomach. Do not get too hot while exercising and avoid places with high temperatures. Call your doctor if you become overheated and cannot cool down. Make sure your doctor knows if you are pregnant. Do not use cariprazine during the later part of a pregnancy unless your doctor tells you to. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. cariprazine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Blurred vision chills dizziness drooling fever headache inability to move the eyes inability to sit still increased blinking or spasms of the eyelid loss of balance control muscle trembling, jerking, or stiffness need to keep moving nervousness pounding in the ears restlessness shuffling walk slow or fast heartbeat sticking out of the tongue stiffness of the limbs trouble with breathing, speaking, or swallowing twisting movements of the body uncontrolled movements, especially of the face, neck, arms, or legs unusual facial expressions Less common Bladder pain bloody or cloudy urine difficult, burning, or painful urination fast, pounding, or irregular heartbeat or pulse frequent urge to urinate lower back or side pain muscle aches sore throat stuffy or runny nose unusual tiredness or weakness Incidence not known Confusion convulsions double vision drooling high fever increased sweating lip smacking or puckering muscle trembling, jerking, or stiffness puffing of the cheeks rapid or worm-like movements of the tongue severe muscle stiffness uncontrolled chewing movements unusually pale skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain diarrhea difficulty having a bowel movement (stool) nausea sleepiness or unusual drowsiness trouble sleeping Less common Acid or sour stomach anxiety back pain belching cough decreased appetite difficulty with moving dry mouth heartburn indigestion irritability muscle pain or stiffness pain in the arms, joints, or legs rash shaking stomach discomfort or upset weight gain Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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Next Side Effects Print this page Add to My Med List More about cariprazine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 92 Reviews Add your own review/rating Drug class: atypical antipsychotics Consumer resources Cariprazine Other brands: Vraylar Professional resources Cariprazine Hydrochloride (AHFS Monograph) Cariprazine (Wolters Kluwer) Related treatment guides Bipolar Disorder Schizophrenia} Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Atypical antipsychotics Related Drugs Bipolar Disorder Seroquel , lithium , quetiapine , lamotrigine , Abilify , Lamictal , Depakote , risperidone , carbamazepine , olanzapine , divalproex sodium , Risperdal , More... Schizophrenia Seroquel , quetiapine , Abilify , risperidone , olanzapine , Risperdal , aripiprazole , Zyprexa , Latuda , Geodon , ziprasidone , clozapine , More... Cariprazine Rating 92 User Reviews 6.7 /10 92 User Reviews 6.7 Rate it! Help and Support Looking for answers? Ask a question or go join the cariprazine support group to connect with others who have similar interests.} } abruptly
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