most space Alprolix (Intravenous) Generic Name: factor ix fc fusion protein recombinant (Intravenous route) FAK-tor NINE Fc FUE-zhun PROE-teen ree-KOM-bi-nant Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Alprolix Available Dosage Forms: Powder for Solution Slideshow Understanding Insulin: What You Need To Know Uses For Alprolix Factor IX Fc fusion protein recombinant injection is used in patients with hemophilia B (congenital Factor IX deficiency) to control or prevent bleeding episodes, or prevent bleeding during surgery. Factor IX is a protein that is produced naturally in the body. Alprolix is a man-made protein produced to replicate the naturally occurring factor IX in the body. It is used to stop bleeding by helping the blood to clot in patients with hemophilia B. This medicine is to be given only by or under the supervision of your doctor or other health care professional. Before Using Alprolix In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Alprolix in children. However, children younger than 12 years of age may need an adjustment in the dose of Alprolix , as determined by your child's doctor. Geriatric Although appropriate studies on the relationship of age to the effects of Alprolix have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Blood clots or a history of medical problems caused by blood clots Use with caution. These conditions may increase the risk of developing blood clots. Patients with factor IX inhibitors May increased risk of having an allergic reaction. Proper Use of Alprolix A doctor or other trained health professional will give you or your child this medicine. You may also be trained to administer this medication yourself. This medicine is given through a needle placed in one of your veins. This medicine comes with a patient information leaflet. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand. Precautions While Using Alprolix It is very important that your doctor check you closely while you or your child are receiving this medicine to make sure it is working properly. Blood tests will be needed to check for unwanted effects. This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a rash, itching skin, difficulty with swallowing, dizziness, a fast heartbeat, lightheadedness or fainting, restlessness, trouble breathing, swelling in your face, hands, tongue, or throat, or chest pain after you receive the medicine. This medicine may increase your chance of having blood clotting problems. Tell your doctor right away if you have a sudden or severe headache, problems with vision or speech, chest pain, shortness of breath, or numbness or weakness while you are receiving this medicine. Tell your doctor if this medicine does not prevent or stop bleeding as expected. Alprolix Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: Rare Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fast, irregular, pounding, or racing heartbeat or pulse sweating Incidence not known Cough difficulty breathing hives, itching, or skin rash pain in the chest, groin, or legs, especially the calves puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue severe, sudden headache slurred speech sudden loss of coordination sudden, severe weakness or numbness in the arm or leg sudden, unexplained shortness of breath tightness or pain in the chest vision changes Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Headache Rare Burning, itching, numbness, prickling, or tingling feelings in the mouth change or loss of taste pain in the injection site Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Alprolix (coagulation factor ix) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En EspaƱol 0 Reviews Add your own review/rating Drug class: miscellaneous coagulation modifiers Consumer resources Alprolix Other brands: BeneFix , Alphanine SD , Idelvion , Ixinity , ... +2 more Professional resources Alprolix (AHFS Monograph) Related treatment guides Hemophilia B} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Manufacturer Biogen Drug Class Miscellaneous coagulation modifiers Related Drugs Hemophilia B BeneFix , NovoSeven RT , Profilnine SD , Alphanine SD , Idelvion , factor ix complex , coagulation factor viia , More... 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