weakness [1%:1.5 to 3 times ULN and AST 10 times ULN) or severe (bilirubin >3 to 5 times ULN) hepatic impairment had ~20% increase in AUC compared to patients with normal hepatic function. Use: Labeled Indications US labeling: Breast cancer, metastatic: Treatment of refractory (metastatic) or relapsed (within 6 months of adjuvant therapy) breast cancer after failure of combination chemotherapy (including anthracycline-based therapy unless clinically contraindicated) Non-small cell lung cancer (NSCLC): First-line treatment of locally advanced or metastatic NSCLC (in combination with carboplatin) in patients ineligible for curative surgery or radiation therapy Pancreatic adenocarcinoma: First-line treatment of metastatic adenocarcinoma of the pancreas (in combination with gemcitabine) Canadian labeling: Breast cancer, metastatic: Treatment of metastatic breast cancer Pancreatic adenocarcinoma: First-line treatment of metastatic adenocarcinoma of the pancreas (in combination with gemcitabine) Off Label Uses Melanoma, metastatic Data from a phase II study supports the use of paclitaxel (protein bound) as monotherapy in the treatment of patients with metastatic melanoma [Hersh 2010] . Additional trials may be necessary to further define the role of paclitaxel (protein bound) in this condition. Ovarian, fallopian tube, or primary peritoneal cancers (recurrent) Data from Phase II studies supports the use of paclitaxel (protein bound) in the treatment of recurrent or persistent ovarian, fallopian tube, or primary peritoneal cancers [Coleman 2011] , [Teneriello 2009] . Additional trials may be necessary to further define the role of paclitaxel (protein bound) in this condition. Contraindications Baseline neutrophil count of] Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Paclitaxel protein-bound Rating 6 User Reviews 7.8 /10 6 User Reviews 7.8 Rate it! Drug Class Mitotic inhibitors Related Drugs mitotic inhibitors Taxol , Taxotere , paclitaxel , Abraxane , docetaxel , etoposide Pancreatic Cancer fluorouracil , Tarceva , gemcitabine , Gemzar , Abraxane , Afinitor , More... Breast Cancer, Metastatic anastrozole , tamoxifen , letrozole , Arimidex , Femara , Xeloda , More... Non-Small Cell Lung Cancer Avastin , methotrexate , Taxol , Opdivo , cisplatin , Taxotere , More... 1 more conditions... equipment
that specific PACLitaxel (Protein Bound)
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