politician dofetilide (Oral route) doe-FET-i-lide Oral route(Capsule) To minimize the risk of induced arrhythmia, patients initiated or re-initiated on dofetilide should be placed for a minimum of 3 days in a facility that can provide calculations of creatinine clearance, continuous ECG monitoring, and cardiac resuscitation . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Tikosyn Available Dosage Forms: Capsule Therapeutic Class: Antiarrhythmic, Group III Chemical Class: Methanesulfonanilide Slideshow Drug Treatments for Rheumatoid Arthritis - What Are Your Options? Uses For dofetilide Dofetilide is used to correct irregular heartbeat of patients with atrial fibrillation or atrial flutter to a normal heart rhythm. Dofetilide belongs to the group of medicines known as antiarrhythmics. It works by slowing nerve impulses in the heart. dofetilide is available only with your doctor's prescription. Before Using dofetilide In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dofetilide, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to dofetilide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of dofetilide in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dofetilide in the elderly. However, elderly patients are more likely to have kidney problems, which may require caution and an adjustment in the dose for patients receiving dofetilide. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking dofetilide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using dofetilide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Amisulpride Bepridil Cimetidine Cisapride Dolutegravir Dronedarone Fingolimod Fluconazole Hydrochlorothiazide Itraconazole Ketoconazole Levomethadyl Megestrol Mesoridazine Pimozide Piperaquine Posaconazole Prochlorperazine Saquinavir Sparfloxacin Sulfamethoxazole Terfenadine Thioridazine Trimethoprim Verapamil Vernakalant Ziprasidone Using dofetilide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acecainide Alfuzosin Amiloride Amiodarone Amitriptyline Amoxapine Anagrelide Apomorphine Aprindine Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Artemether Asenapine Astemizole Azimilide Azithromycin Azosemide Bedaquiline Bemetizide Bendroflumethiazide Benzthiazide Bretylium Bumetanide Buserelin Buthiazide Chloral Hydrate Chloroquine Chlorothiazide Chlorpromazine Chlorthalidone Ciprofloxacin Citalopram Clarithromycin Clomipramine Clopamide Clozapine Crizotinib Cyclobenzaprine Cyclopenthiazide Cyclothiazide Dabrafenib Dasatinib Degarelix Delamanid Desipramine Deslorelin Deutetrabenazine Diazoxide Dibenzepin Digoxin Dirithromycin Disopyramide Dofetilide Dolasetron Domperidone Donepezil Doxepin Droperidol Efavirenz Enflurane Erythromycin Escitalopram Ethacrynic Acid Etozolin Fenquizone Flecainide Fluoxetine Foscarnet Furosemide Gatifloxacin Gemifloxacin Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Halothane Histrelin Hydroflumethiazide Hydroxychloroquine Hydroxyzine Ibutilide Iloperidone Imipramine Indapamide Isoflurane Isradipine Ivabradine Josamycin Lamotrigine Lapatinib Leuprolide Levofloxacin Lidoflazine Lopinavir Lorcainide Lumefantrine Mefloquine Metformin Methadone Methyclothiazide Metolazone Metronidazole Mifepristone Moricizine Moxifloxacin Nafarelin Nilotinib Norfloxacin Nortriptyline Octreotide Ofloxacin Ondansetron Paliperidone Panobinostat Pasireotide Pazopanib Pentamidine Pimavanserin Piretanide Pitolisant Polythiazide Prilocaine Probucol Procainamide Promethazine Propafenone Protriptyline Quetiapine Quinethazone Quinidine Ranolazine Ribociclib Risperidone Roxithromycin Salmeterol Sematilide Sertindole Sevoflurane Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Spiramycin Sulpiride Sultopride Sunitinib Tacrolimus Tedisamil Telavancin Telithromycin Tetrabenazine Tizanidine Toremifene Torsemide Trazodone Triamterene Trichlormethiazide Trifluoperazine Trimipramine Triptorelin Troleandomycin Vandetanib Vardenafil Vasopressin Vemurafenib Vinflunine Voriconazole Xipamide Zolmitriptan Zotepine Zuclopenthixol Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Other Medical Problems The presence of other medical problems may affect the use of dofetilide. Make sure you tell your doctor if you have any other medical problems, especially: Electrolyte imbalance (eg, low magnesium or potassium levels in the blood) or Heart disease or Heart rhythm problems Use with caution. May make these conditions worse. Heart rhythm problem (eg, congenital long QT syndrome) or Kidney disease, severe or Patients receiving dialysis treatment Should not be used in patients with these conditions. Kidney disease Higher blood levels may occur, which may increase the chance of side effects. Your doctor may need to change your dose. Liver disease, severe Use with caution. dofetilide has not been studied in patients with this condition. Proper Use of dofetilide Take dofetilide exactly as directed by your doctor . Do not take more or less of it, and do not take it more often than your doctor ordered. dofetilide works best when there is a constant amount in the body. To help keep the amount constant, it is best to take the doses at the same time every day. Your doctor will start you on dofetilide in the hospital in order to check your heart rhythm and find the right dose for you. You will need to stay in the hospital for at least 3 days so the doctor can monitor your progress. dofetilides comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions. You may take dofetilide with or without food. Dosing The dose of dofetilide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dofetilide. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (capsules): For abnormal heart rhythm: Adults 125 to 500 micrograms (mcg) two times a day. Your doctor may adjust your dose as needed. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of dofetilide, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using dofetilide It is very important that your doctor check your progress at regular visits to make sure that dofetilide is working properly and to check for unwanted effects. This will allow for changes to be made in the amount of medicine you are taking, if necessary. Do not use dofetilide together with cimetidine, dolutegravir, hydrochlorothiazide, hydrochlorothiazide/triamterene, ketoconazole, megestrol, prochlorperazine, trimethoprim, trimethoprim/sulfamethoxazole, or verapamil. Using these medicines together may cause serious unwanted effects . Do not eat grapefruit or drink grapefruit juice while you are using dofetilide. Grapefruit and grapefruit juice may change the amount of dofetilide that is absorbed in the body. Do not take other medicines unless they have been discussed with your doctor. This especially includes potassium supplements or salt substitutes containing potassium, or certain diuretics (eg, amiloride, spironolactone, triamterene). dofetilide Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Dizziness fainting fast heartbeat Less common Chest pain confusion facial or flaccid paralysis numbness or tingling of the hands, feet, or face paralysis pounding, slow heartbeat slurred speech swelling of the ankles, arms, face, feet, fingers, legs, lips, tongue, or throat troubled breathing unexplained shortness of breath unusual tiredness or weakness weight gain yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Abdominal or stomach pain accidental injury back pain chills cough diarrhea fever flu-like symptoms general feeling of discomfort or illness headache joint pain loss of appetite migraine muscle aches and pains nausea rash runny nose shivering sneezing sore throat sweating trouble sleeping vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about dofetilide Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 41 Reviews Add your own review/rating Drug class: group III antiarrhythmics Consumer resources Dofetilide Other brands: Tikosyn Professional resources Dofetilide (AHFS Monograph) Dofetilide (FDA) Dofetilide (Wolters Kluwer) Related treatment guides Arrhythmia} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer Greenstone LLC Drug Class Group III antiarrhythmics Related Drugs Arrhythmia propranolol , amiodarone , verapamil , lidocaine , Inderal , Tikosyn , Pacerone , mexiletine , Calan , Cordarone , quinidine , Calan SR , Mexitil , procainamide , Verelan , disopyramide , Norpace , Nexterone , Isoptin SR , Cordarone IV , Ethmozine , Norpace CR , More... Dofetilide Rating 41 User Reviews 7.9 /10 41 User Reviews 7.9 Rate it! Dofetilide Images Dofetilide systemic 125 mcg (ML 125) View all images Related Questions & Answers Can it cause muscle pain, or exascerbate arthritis? Can dofetilide cause muscle pain, cramping and exacerbate arthritis? I'm taking Tikosyn (dofetilide), and was told not to take aspirin products. Is it save to take? Read more questions} } thrust back
refill dofetilide (Oral route) politely
EmoticonEmoticon