work out Lumizyme (Intravenous) Generic Name: alglucosidase alfa (Intravenous route) al-gloo-KOE-si-dase AL-fa Intravenous route(Powder for Solution) Life-threatening anaphylactic, severe allergic, and immune-mediated reactions have been observed in patients during and after alglucosidase alfa infusion. Observe patients closely and appropriate treatment and supportive measures should be readily available. Infantile onset Pompe disease patients with compromised cardiac or respiratory function may be at risk of serious acute exacerbation due to fluid overload, and require additional monitoring . Overview Side Effects Dosage Professional Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Lumizyme Myozyme Available Dosage Forms: Powder for Solution Therapeutic Class: Enzyme Replacement Pharmacologic Class: Enzyme Slideshow A Joint Effort: A Provider's Guide To Orthopedic Pain Options Uses For Lumizyme Alglucosidase alfa injection is an enzyme that treats infantile-onset Pompe disease, which is also called glycogen storage disease type II. Alglucosidase alfa contains a human enzyme called acid alpha-glucosidase. This enzyme helps with the digestion and absorption of glycogen. People with Pompe disease are not able to make enough of this enzyme. This medicine is available only with your doctor's prescription. Before Using Lumizyme In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of alglucosidase alfa injection in children. Geriatric No information is available on the relationship of age to the effects of alglucosidase alfa injection in the geriatric population. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Breathing problems or Cardiac hypertrophy (heart is larger than normal) or Heart rhythm problems (eg, arrhythmia) or Lung disease Use with caution. May make these conditions worse. Proper Use of alglucosidase alfa This section provides information on the proper use of a number of products that contain alglucosidase alfa. It may not be specific to Lumizyme. Please read with care. A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in one of your veins. This medicine must be given slowly, so the needle will remain in place for a few hours. You or your child may also receive medicines to help prevent possible allergic reactions to the injection. Precautions While Using Lumizyme It is very important that your doctor check the progress of you or your child at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects. This medicine may cause chest pain, fever, chills, itching, hives or a rash, a fast heartbeat, flushing of the face, dizziness, fainting, or lightheadedness, trouble breathing, or swelling of the face, tongue, and throat within a few hours after it is given. Check with your doctor or nurse right away if you or your child have any of these symptoms. This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash, itching, hoarseness, lightheadedness, dizziness, or fainting, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine. Lumizyme Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Blue lips, fingernails, or skin body aches or pain chest discomfort or pain chills cough difficult or labored breathing difficulty with swallowing dizziness dry, red, hot, or irritated skin ear congestion fast, pounding, or irregular heartbeat or pulse feeling of warmth fever headache hives, itching, or skin rash increased sweating irregular, fast, slow, or shallow breathing lightheadedness, dizziness, or fainting loss of voice nasal congestion pain pale skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue rapid shallow breathing redness of the face, neck, arms, and occasionally, upper chest redness or pain at the catheter site runny nose shakiness in the legs, arms, hands, or feet slow or irregular heartbeat sneezing sore throat swollen, painful, or tender lymph glands in the neck, armpit, or groin tightness in the chest trembling or shaking of the hands or feet troubled breathing troubled breathing with exertion unusual bleeding or bruising unusual tiredness or weakness Less common Blood in the urine convulsions decreased urine dry mouth increased thirst loss of appetite mood changes muscle pain or cramps nausea or vomiting numbness or tingling in the hands, feet, or lips pain in the groin or genitals sharp back pain just below the ribs Incidence not known Blue-green to black skin discoloration blurred vision confusion dilated neck veins extreme fatigue heart stops inability to speak no breathing no pulse or blood pressure pain, redness, swelling, or sloughing of the skin at the place of injection seizures severe or sudden headache severe pain in the chest slurred speech sudden and severe weakness in the arm or leg on one side of the body sudden onset of severe breathing difficulty swelling of the face, fingers, feet, or lower legs temporary blindness unconscious weight gain Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain acid or sour stomach belching body aches or pain change in hearing congestion constipation dryness or soreness of the throat ear discomfort or pain ear drainage earache feeling of constant movement of self or surroundings general feeling of discomfort or illness heartburn hoarseness indigestion muscle or bone pain, stiffness, or tightness muscle twitching redness of the skin redness or swelling in the ear sensation of spinning sore mouth or tongue stomach discomfort, upset, or pain tender, swollen glands in the neck upper abdominal or stomach pain voice changes welts white patches in the mouth or on the tongue Less common Bloody nose sleepiness or unusual drowsiness Incidence not known Burning, dry, or itching eyes discharge, excessive tearing muscle spasm redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Lumizyme (alglucosidase alfa) Side Effects During Pregnancy or Breastfeeding Dosage Information Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: lysosomal enzymes Consumer resources Lumizyme Lumizyme injection Other brands: Myozyme Professional resources Lumizyme (FDA) Alglucosidase Alfa (AHFS Monograph) Related treatment guides Pompe disease} Drug Status Rx Availability Prescription only Pregnancy Category Risk depends on usage N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Genzyme Corporation Sanofi-Aventis U.S. LLC Drug Class Lysosomal enzymes Related Drugs Pompe disease Myozyme , alglucosidase alfa , More... Lumizyme Rating No Reviews - Be the first! 1.0 /10 No Reviews - Be the first! 1.0 Rate it! Related Questions & Answers What is the average cost of treatment with Lumizyme? Read more questions} } it's your decision
more potent Lumizyme (Intravenous) all of us
EmoticonEmoticon