surgical treatment Trecator-SC Side Effects Generic Name: ethionamide Overview Side Effects Dosage Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Note: This document contains side effect information about ethionamide. Some of the dosage forms listed on this page may not apply to the brand name Trecator-SC. For the Consumer Applies to ethionamide: oral tablet Along with its needed effects, ethionamide (the active ingredient contained in Trecator-SC) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking ethionamide: Less common Clumsiness or unsteadiness confusion mental depression numbness, tingling, burning, or pain in the hands and feet yellow eyes or skin Rare Blindness or vision changes blue-yellow color blindness blurred vision or loss of vision, with or without eye pain burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings changes in menstrual periods coldness decreased sexual ability (in males) decreased vision difficulty in concentrating dry, puffy skin fast heartbeat fever hives, itching, or rash hoarseness increased hunger increased sensitivity of the skin to sunlight irritation joint pain, stiffness, or swelling redness or other discoloration of the skin severe sunburn shakiness swelling of the eyelids, face, lips, hands, or feet swelling of the front part of the neck tightness in the chest troubled breathing or swallowing weakness in the hands or feet weight gain Incidence not known Chills cold sweats coma cool, pale skin dark urine dizziness general tiredness and weakness headache light-colored stools nausea and vomiting nightmares seizures slurred speech unusual tiredness or weakness upper right abdominal or stomach pain yellow eyes and skin Some side effects of ethionamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain diarrhea increased watering of the mouth loss of appetite metallic taste swelling or inflammation of the mouth weight loss Incidence not known Blemishes on the skin decreased interest in sexual intercourse enlargement of the breasts (in males) inability to have or keep an erection loss in sexual ability, desire, drive, or performance pimples For Healthcare Professionals Applies to ethionamide: oral tablet Gastrointestinal Gastrointestinal side effects are the most common side effects of ethionamide (the active ingredient contained in Trecator-SC) and may be dose-related. They have included nausea, vomiting, diarrhea, abdominal pain excessive salivation, metallic taste, stomatitis, anorexia, and weight loss. Approximately one-half of patients cannot tolerate 1 gram as a single dose. [ Ref ] Nervous system Nervous system side effects have included psychotic disturbances, mental depression, drowsiness, dizziness, restlessness, headache, peripheral neuritis, and a pellagra-like syndrome. Concomitant pyridoxine has been recommended to prevent or relieve neurotoxic effects. [ Ref ] Ocular Ocular side effects have rarely included optic neuritis, diplopia, and blurred vision. [ Ref ] Hepatic Hepatic side effects have included transient increases in serum bilirubin, SGOT, SGPT, and hepatitis with or without jaundice. [ Ref ] Hypersensitivity Hypersensitivity reactions have rarely included rash, photosensitivity, thrombocytopenia, and purpura. [ Ref ] Metabolic Metabolic side effects have included hypoglycemia and hypothyroidism. [ Ref ] Genitourinary Genitourinary side effects have included gynecomastia and impotence. [ Ref ] Dermatologic Dermatologic side effects have included rash and acne. [ Ref ] Hematologic Hematologic side effects have included thrombocytopenia and purpura. [ Ref ] Cardiovascular Cardiovascular side effects have included postural hypotension. [ Ref ] References 1. "Product Information. Trecator-SC (ethionamide)." Wyeth-Ayerst Laboratories, Philadelphia, PA. 2. McDonnell ME, Braverman LE, Bernardo J "Hypothyroidism due to ethionamide." N Engl J Med 352 (2005): 2757-9 3. Hussey HH "Editorial: Gynecomastia." JAMA 228 (1974): 1423 Some side effects of Trecator-SC may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA . Next Dosage Print this page More about Trecator-SC (ethionamide) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: nicotinic acid derivatives Consumer resources Trecator-SC (Advanced Reading) Professional resources Ethionamide (AHFS Monograph) Other Formulations Trecator Related treatment guides Tuberculosis, Active Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. 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Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Drug Class Nicotinic acid derivatives Related Drugs Tuberculosis, Active ciprofloxacin , Levaquin , levofloxacin , rifampin , moxifloxacin , Avelox , isoniazid , ethambutol , amikacin , gatifloxacin , streptomycin , pyrazinamide , Floxin , Rifadin , Amikin , Myambutol , cycloserine , Tequin , isoniazid / pyrazinamide / rifampin , rifapentine , kanamycin , ethionamide , Rifamate , More... Trecator-SC Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! leading
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