a lot of people epoetin beta and methoxy polyethylene glycol Generic Name: epoetin beta and methoxy polyethylene glycol (e POE e tin BAY ta meth OX ee pol ee ETH il een GLYE kol) Brand Name: Mircera Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A What is epoetin beta and methoxy polyethylene glycol? Epoetin beta and methoxy polyethylene glycol is a man-made form of a protein normally produced by the kidneys that helps your body produce red blood cells. When your body does not make enough of this protein because of kidney failure, you can develop a condition called anemia (lack of red blood cells). Epoetin beta and methoxy polyethylene glycol is a combination medicine used to treat anemia in people with chronic kidney disease. This medicine is not for treating anemia caused by cancer chemotherapy. Epoetin beta and methoxy polyethylene glycol may also be used for purposes not listed in this medication guide. Slideshow Diabetic Nerve Pain: Symptoms And Treatment What is the most important information I should know about epoetin beta and methoxy polyethylene glycol? You should not use this medicine if you have uncontrolled high blood pressure or if you have ever had pure red cell aplasia (PRCA). Epoetin beta and methoxy polyethylene glycol can increase your risk of serious or fatal side effects, including heart attack, stroke, or blood clot. Call your doctor or get emergency medical help if you have symptoms such as: chest pain, nausea, sweating, sudden numbness or weakness, a cold or pale arm or leg, confusion, or problems with speech or balance. What should I discuss with my healthcare provider before using epoetin beta and methoxy polyethylene glycol? You should not use epoetin beta and methoxy polyethylene glycol if you are allergic to it, or if you have: uncontrolled hypertension (high blood pressure); or if you have ever had a type of anemia called pure red cell aplasia (PRCA). To make sure this medicine is safe for you, tell your doctor if you have ever had: heart disease, high blood pressure; a heart attack, stroke, or blood clot; a seizure; kidney disease (or if you are on dialysis); or cancer. This medicine may shorten remission time or survival time in people with certain types of cancer. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether epoetin beta and methoxy polyethylene glycol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I use epoetin beta and methoxy polyethylene glycol? This medicine is usually given once every 2 weeks or once per month. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Never use more than your recommended dose. Epoetin beta and methoxy polyethylene glycol is injected under the skin, or into a vein through an IV. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Your care provider will show you the best places on your body to inject epoetin beta and methoxy polyethylene glycol. Use a different place each time you give an injection. Do not inject into the same place two times in a row. Do not shake the prefilled syringe or you may ruin the medicine. Prepare your dose only when you are ready to give an injection. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. Each single-use prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside. Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets. Call your doctor if you have signs that your body is not responding to this medicine (pale skin, feeling light-headed or short of breath, unusual tiredness, or lack of energy). Your blood will need to be tested often. Your blood pressure will also need to be checked. Your next dose may be delayed based on the results of these tests. If you need surgery, tell the surgeon ahead of time that you are using epoetin beta and methoxy polyethylene glycol. You may need to take medicine to prevent blood clots for a short time after your surgery. Epoetin beta and methoxy polyethylene glycol is only part of a treatment program that may also include diet, regular dialysis treatments, and special medical care. Follow your doctor's instructions very closely. Store in the refrigerator. Do not freeze . Keep the medicine in the original container until you are ready to give an injection. You may also store the medicine for up to 30 days at cool room temperature. Protect from light. What happens if I miss a dose? Call your doctor for instructions if you miss a dose of epoetin beta and methoxy polyethylene glycol. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using epoetin beta and methoxy polyethylene glycol? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Epoetin beta and methoxy polyethylene glycol side effects Get emergency medical help if you have signs of an allergic reaction : hives, sweating; fast heartbeats; difficult breathing; dizziness, fainting; swelling of your face, lips, tongue, or throat. This medicine can increase your risk of serious or fatal side effects. Call your doctor or get emergency medical help if you have: increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed; symptoms of heart failure--shortness of breath (even with mild exertion), swelling, rapid weight gain; heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; or signs of a stroke or blood clot--sudden numbness or weakness (especially on one side of the body), slurred speech, sudden confusion, problems with vision or balance, a cold or pale arm or leg. Also call your doctor at once if you have a seizure (convulsions), or signs that you may have a seizure, such as: sudden mood changes; unusual tiredness; sensitivity to light or noise; or trouble concentrating. Common side effects may include: diarrhea; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Epoetin beta and methoxy polyethylene glycol dosing information Usual Adult Dose for Anemia Associated with Chronic Renal Failure: 1) For Patients Not Currently Treated with an erythropoiesis-stimulating agent (ESA): Initial dose: 0.6 mcg/kg body weight administered as a single IV or subcutaneous injection once every two weeks Epoetin beta-methoxy polyethylene glycol should be dosed to achieve and maintain hemoglobin between 10 and 12 g/dL. Once the hemoglobin has been maintained within this range, epoetin beta-methoxy polyethylene glycol may be administered once monthly using a dose that is twice that of the every two week dose and subsequently titrated as necessary. 2) For Patients Currently Treated with an erythropoiesis-stimulating agent (ESA): Epoetin beta-methoxy polyethylene glycol can be administered once every two weeks or once monthly to patients whose hemoglobin has been stabilized by treatment with an ESA. The dose of epoetin beta-methoxy polyethylene glycol, given as a single IV or subcutaneous injection, should be based on the total weekly ESA dose at the time of conversion. If the previous weekly epoetin alfa dose was less than 8000 units per week or the previous weekly darbepoetin alfa dose was less than 40 mcg per week, then the epoetin beta-methoxy polyethylene glycol dose would be 120 mcg per month or 60 mcg every two weeks. If the previous weekly epoetin alfa dose was from 8000 units to 16,000 units per week or the previous weekly darbepoetin alfa dose was from 40 mcg to 80 mcg per week, then the epoetin beta-methoxy polyethylene glycol dose would be 200 mcg per month or 100 mcg every two weeks. If the previous weekly epoetin alfa dose was greater than 16,000 units per week or the previous weekly darbepoetin alfa dose was greater than 80 mcg per week, then the epoetin beta-methoxy polyethylene glycol dose would be 360 mcg per month or 180 mcg every two weeks. Usual Geriatric Dose for Anemia Associated with Chronic Renal Failure: Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. What other drugs will affect epoetin beta and methoxy polyethylene glycol? Other drugs may interact with epoetin beta and methoxy polyethylene glycol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using. Next Side Effects Print this page Add to My Med List More about epoetin beta-methoxy polyethylene glycol Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: recombinant human erythropoietins Consumer resources Methoxy Polyethylene Glycol-Epoetin Beta Methoxy polyethylene glycol-epoetin beta Injection (Advanced Reading) Other brands: Mircera Professional resources Methoxy Polyethylene Glycol-Epoetin Beta (Wolters Kluwer) Related treatment guides Anemia Associated with Chronic Renal Failure Where can I get more information? Your pharmacist can provide more information about epoetin beta and methoxy polyethylene glycol. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01. Date modified: December 03, 2017 Last reviewed: September 26, 2017} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Recombinant human erythropoietins Related Drugs Anemia Associated with Chronic Renal Failure ferrous sulfate , Procrit , Aranesp , Feosol Original , Epogen , epoetin alfa , Fergon , Ferrousal , FeroSul , darbepoetin alfa , Ferrlecit , Slow Fe , Feraheme , Hemocyte , Infed , iron dextran , Ferrocite , sodium ferric gluconate complex , ferumoxytol , More... Epoetin beta-methoxy polyethylene glycol Rating No Reviews - Be the first! 8.5 /10 No Reviews - Be the first! 8.5 Rate it! Related Questions & Answers Mds anemia - can you identify with my symptoms and how I'm feeling? Read more questions} } searching for
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