so that it will saxagliptin (Oral route) sax-a-GLIP-tin Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Onglyza Available Dosage Forms: Tablet Therapeutic Class: Antidiabetic Pharmacologic Class: Dipeptidyl Peptidase IV Inhibitor Slideshow Aging Issues: 12 of the Most Common Health Concerns Affecting Seniors Uses For saxagliptin Saxagliptin is used with proper diet and exercise to treat high blood sugar (glucose) levels in patients with type 2 diabetes. Saxagliptin helps to control blood sugar levels by making the pancreas gland release more insulin. It also signals the liver to stop producing sugar when there is too much sugar in the blood. saxagliptin does not help patients who have insulin-dependent or type 1 diabetes. saxagliptin is available only with your doctor's prescription. Before Using saxagliptin In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For saxagliptin, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to saxagliptin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of saxagliptin in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of saxagliptin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving saxagliptin. Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking saxagliptin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using saxagliptin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Balofloxacin Besifloxacin Ceritinib Ciprofloxacin Eliglustat Enoxacin Fleroxacin Flumequine Gatifloxacin Gemifloxacin Lanreotide Levofloxacin Lomefloxacin Moxifloxacin Nadifloxacin Norfloxacin Octreotide Ofloxacin Pasireotide Pazufloxacin Pefloxacin Prulifloxacin Rufloxacin Simeprevir Sparfloxacin Thioctic Acid Tosufloxacin Using saxagliptin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acebutolol Acetohexamide Atenolol Betaxolol Bisoprolol Carteolol Carvedilol Celiprolol Chlorpropamide Esmolol Gliclazide Glimepiride Glipizide Gliquidone Glyburide Insulin Insulin Aspart, Recombinant Insulin Bovine Insulin Degludec Insulin Detemir Insulin Glulisine Insulin Lispro, Recombinant Labetalol Levobunolol Metipranolol Metoprolol Nadolol Nebivolol Oxprenolol Penbutolol Pindolol Practolol Propranolol Sotalol Timolol Tolazamide Tolbutamide Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of saxagliptin. Make sure you tell your doctor if you have any other medical problems, especially: Alcohol, excessive use or Gallstones, history of or Hypertriglyceridemia (high triglycerides or fats in the blood) or Pancreatitis, history of Use with caution. May cause side effects to become worse. Angioedema (swelling of the face, lips, tongue, throat, arms, or legs), history with other dipeptidyl peptidase-4 (DPP-4) inhibitors Use with caution. May increase the risk of this condition occurring again. Heart failure, history of or Kidney disease May increase risk for heart failure. Kidney disease, moderate or severe Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of saxagliptin Take saxagliptin exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects. saxagliptin comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions. Carefully follow the special meal plan your doctor gave you . This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Swallow the tablet whole. Do not break, cut, or chew it. Take saxagliptin with or without food. Dosing The dose of saxagliptin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of saxagliptin. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For Type 2 diabetes: Adults 2.5 or 5 milligrams (mg) once a day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of saxagliptin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using saxagliptin It is very important that your doctor check your progress at regular visits to make sure that saxagliptin is working properly. Blood and urine tests may be needed to check for unwanted effects. Pancreatitis (swelling and inflammation of the pancreas) may occur while you are using saxagliptin. Check with your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness. If you are rapidly gaining weight, having trouble breathing, chest pain, extreme tiredness or weakness, irregular breathing, irregular heartbeat, or excessive swelling of the hands, wrist, ankles, or feet, check with your doctor immediately. These may be symptoms of a heart problem. saxagliptin may cause serious allergic reactions, including anaphylaxis, angioedema, and serious skin reactions. These conditions may be life-threatening and require immediate medical attention. Check with your doctor right away if you have a rash, itching, a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, skin flaking or peeling, trouble with breathing, or chest tightness while you are using saxagliptin. saxagliptin may cause hypoglycemia (low blood sugar). This is more common when saxagliptin is taken together with certain medicines. Low blood sugar must be treated before it causes you to pass out (unconsciousness). People feel different symptoms of low blood sugar . It is important that you learn which symptoms you usually have so you can treat it quickly. Talk to your doctor about the best way to treat low blood sugar. Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. High blood sugar can be very serious and must be treated right away. It is important that you learn which symptoms you have in order to treat it quickly. Talk to your doctor about the best way to treat high blood sugar. saxagliptin may cause severe joint pain. Call your doctor right away if you have severe joint pain with saxagliptin. saxagliptin may cause bullous pemphigoid. Tell your doctor if you have large, hard skin blisters while using saxagliptin. Before you have any medical tests, tell the medical doctor in charge that you are taking saxagliptin. The results of some tests may be affected by saxagliptin. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. saxagliptin Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Anxiety bladder pain bloating or swelling of the face, arms, hands, lower legs, or feet bloody or cloudy urine blurred vision body aches or pain chills cold sweats confusion cool, pale skin cough depression difficult, burning, or painful urination difficulty with breathing dizziness ear congestion fast heartbeat fever frequent urge to urinate headache increased hunger loss of voice lower back or side pain nasal congestion nausea nightmares rapid weight gain runny nose seizures shakiness slurred speech sneezing sore throat tingling of the hands or feet unusual tiredness or weakness unusual weight gain or loss Incidence not known Chest pain constipation darkened urine decreased urine output difficulty with swallowing dilated neck veins extreme fatigue flaking or peeling of the skin hives or skin rash indigestion irregular breathing irregular heartbeat large, hard skin blisters large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of appetite pains in the stomach, side, or abdomen, possibly radiating to the back puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue severe joint pain swelling of face, fingers, feet, or lower leg tightness in the chest troubled breathing vomiting weight gain yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Diarrhea pain or tenderness around the eyes and cheekbones redness of the skin weakness welts Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about saxagliptin Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 14 Reviews Add your own review/rating Drug class: dipeptidyl peptidase 4 inhibitors Consumer resources Saxagliptin Other brands: Onglyza Professional resources Saxagliptin Hydrochloride (AHFS Monograph) Saxagliptin (Wolters Kluwer) Related treatment guides Diabetes, Type 2} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Dipeptidyl peptidase 4 inhibitors Related Drugs Diabetes, Type 2 metformin , insulin aspart , glipizide , glimepiride , Januvia , pioglitazone , Victoza , Actos , Tradjenta , Glucophage , glyburide , Janumet , Invokana , Amaryl , Welchol , Onglyza , sitagliptin , Trulicity , Jardiance , Lantus , Farxiga , Levemir , Tresiba , Glucotrol , Bydureon , More... Saxagliptin Rating 14 User Reviews 6.4 /10 14 User Reviews 6.4 Rate it! Related Questions & Answers Why would a physician prescribe this med to me? Saxagliptin - What is the Generic name for this med.? Read more questions} } waiting for
kind of saxagliptin (Oral route) go along with
EmoticonEmoticon