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the suitable eprosartan and hydrochlorothiazide (Oral route) ep-roe-SAR-tan MES-i-late, hye-droe-klor-oh-THYE-a-zide Oral route(Tablet) Drugs that act on the renin-angiotensin system can cause injury or death to the developing fetus when used during the second and third trimesters. When pregnancy is detected, discontinue treatment immediately . Overview Side Effects Professional Interactions Pregnancy More User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Teveten HCT Available Dosage Forms: Tablet Therapeutic Class: Angiotensin II Receptor Antagonist/Thiazide Combination Pharmacologic Class: Eprosartan Chemical Class: Thiazide Slideshow HealthQuiz - Basics About Stroke Signs and Symptoms Uses For eprosartan and hydrochlorothiazide Eprosartan and hydrochlorothiazide combination is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Eprosartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes the blood vessels to tighten. As a result, eprosartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Hydrochlorothiazide is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure. eprosartan and hydrochlorothiazide is available only with your doctor's prescription. Before Using eprosartan and hydrochlorothiazide In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For eprosartan and hydrochlorothiazide, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to eprosartan and hydrochlorothiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of eprosartan and hydrochlorothiazide combination in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of eprosartan and hydrochlorothiazide combination in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking eprosartan and hydrochlorothiazide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using eprosartan and hydrochlorothiazide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Aliskiren Dofetilide Using eprosartan and hydrochlorothiazide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Acetyldigoxin Amphetamine Amtolmetin Guacil Arsenic Trioxide Aspirin Benazepril Benzphetamine Bromfenac Bufexamac Captopril Celecoxib Choline Salicylate Clonixin Cyclophosphamide Deslanoside Dexibuprofen Dexketoprofen Dextroamphetamine Diclofenac Diflunisal Digitalis Digitoxin Digoxin Dipyrone Droperidol Droxicam Enalapril Enalaprilat Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Flecainide Floctafenine Flufenamic Acid Flurbiprofen Fosinopril Ibuprofen Indomethacin Ketanserin Ketoprofen Ketorolac Levomethadyl Lisdexamfetamine Lisinopril Lithium Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Methamphetamine Methotrexate Metildigoxin Moexipril Morniflumate Nabumetone Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Ouabain Oxaprozin Oxyphenbutazone Parecoxib Perindopril Phenylbutazone Piketoprofen Piroxicam Proglumetacin Propyphenazone Proquazone Proscillaridin Quinapril Ramipril Rofecoxib Salicylic Acid Salsalate Sodium Salicylate Sotalol Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Trandolapril Trimethoprim Valdecoxib Using eprosartan and hydrochlorothiazide with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Aminolevulinic Acid Amtolmetin Guacil Bepridil Bromfenac Bufexamac Carbamazepine Celecoxib Cholestyramine Choline Salicylate Clonixin Dexibuprofen Dexketoprofen Diclofenac Diflunisal Dipyrone Droxicam Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Flurbiprofen Ginkgo Gossypol Ibuprofen Indomethacin Ketoprofen Ketorolac Licorice Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Morniflumate Nabumetone Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Phenylbutazone Piketoprofen Piroxicam Proglumetacin Propionic Acid Propyphenazone Proquazone Rofecoxib Salicylic Acid Salsalate Sodium Salicylate Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Topiramate Valdecoxib Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of eprosartan and hydrochlorothiazide. Make sure you tell your doctor if you have any other medical problems, especially: Anuria (not able to pass urine) or Diabetic patients who are also taking aliskiren (Tekturna ) or Sulfa drug allergy (e.g., sulfamethoxazole, sulfasalazine, sulfisoxazole, Azulfidine , Bactrim , Septra ) Should not be used in these patients. Asthma, history of May increase likelihood of having an allergic reaction. Congestive heart failure, severe Use may lead to kidney problems. Diabetes or Electrolyte imbalances (e.g., high or low potassium, magnesium, or sodium in the body) or Fluid imbalances (caused by dehydration, vomiting, or diarrhea) or Glaucoma, secondary angle closure or Gout or Hypercalcemia (high calcium in the blood) or Kidney problems or Liver disease or Myopia, acute (changes in the eyeball causing vision problems) or Systemic lupus erythematosus (an autoimmune disorder) Use with caution. May make these conditions worse. Proper Use of eprosartan and hydrochlorothiazide eprosartan and hydrochlorothiazide should not be the first medicine you use to treat your condition . It is meant to be used only after you have tried other medicines that have not worked or have caused unwanted side effects. In addition to the use of eprosartan and hydrochlorothiazide, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that eprosartan and hydrochlorothiazide will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. You may take eprosartan and hydrochlorothiazide with or without food. Dosing The dose of eprosartan and hydrochlorothiazide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of eprosartan and hydrochlorothiazide. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For high blood pressure: Adults One tablet once a day. Your doctor may increase your dose as needed. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of eprosartan and hydrochlorothiazide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using eprosartan and hydrochlorothiazide It is very important that your doctor check your progress at regular visits to make sure eprosartan and hydrochlorothiazide is working properly. Blood and urine tests may be needed to check for unwanted effects. Using eprosartan and hydrochlorothiazide while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using eprosartan and hydrochlorothiazide, tell your doctor right away. Dizziness, lightheadedness, or fainting may also occur, especially when you get up from a lying or sitting position or if you have been taking a diuretic (water pill). Make sure you know how you react to eprosartan and hydrochlorothiazide before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, stop using eprosartan and hydrochlorothiazide and call your doctor right away . Check with your doctor right away if you become sick while taking eprosartan and hydrochlorothiazide, especially with severe or continuing nausea, vomiting, or diarrhea. These conditions may cause you to lose too much water or salt which may cause low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. Check with your doctor immediately if blurred vision, difficulty reading, eye pain, or any other change in vision occurs during or after treatment. This could be a sign of a serious eye problem. Your doctor may want an eye doctor to check your eyes. eprosartan and hydrochlorothiazide may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests, or if you have any questions, check with your doctor. Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium without first checking with your doctor . Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood pressure. eprosartan and hydrochlorothiazide Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare Abdominal or stomach pain ankle, knee, or great toe joint pain arm, back, or jaw pain bladder pain bloating or swelling of the face, arms, hands, lower legs, or feet bloody or cloudy urine blurred vision chest pain or discomfort chest tightness or heaviness confusion convulsions decreased urine output difficulty breathing difficult, burning, or painful urination dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position dry mouth fast, pounding, or irregular heartbeat or pulse feeling of warmth fever flushed or dry skin frequent urination fruit-like breath odor headache increased hunger increased thirst increased volume of pale, dilute urine itching of the skin joint stiffness or swelling loss of appetite loss of bladder control loss of consciousness lower back or side pain muscle pain or cramps nausea or vomiting nervousness numbness and tingling of the face, fingers, or toes pale, bluish-colored, or cold hands or feet pinpoint red or purple spots on the skin rapid weight gain sudden decrease in the amount of urine sudden sweating unexplained weight loss unusual bleeding or bruising unusual tiredness or weakness unusual weight gain or loss weakness or heaviness of the legs Incidence not known Back, leg, or stomach pains black, tarry stools bleeding gums blistering, peeling, or loosening of the skin bloody or cloudy urine chills constipation cough or hoarseness coughing up blood darkened urine decreased frequency or amount of urine diarrhea difficulty with swallowing drowsiness fever with or without chills general body swelling general feeling of tiredness or weakness hives indigestion irritability large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs nosebleeds pains in the stomach, side, or abdomen, possibly radiating to the back pale skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue red skin lesions, often with a purple center red, irritated eyes skin rash sore throat sores, ulcers, or white spots on the lips or in the mouth swollen or painful glands thickening of bronchial secretions unusual weight loss vision changes weak pulse weight gain yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Rare Acid or sour stomach belching body aches or pain bone pain burning feeling in the chest or stomach burning or stinging of the skin burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings burning, dry, or itching eyes change in hearing cold or flu-like symptoms congestion continuing ringing or buzzing or other unexplained noise in the ears cough producing mucus depression difficulty moving ear drainage earache excess air or gas in the stomach or intestines fear or nervousness feeling of constant movement of self or surroundings feeling unusually cold full feeling headache, severe and throbbing hearing loss heartburn increased sweating irritation in the mouth itching ears lack or loss of strength loose teeth loss of voice multiple swollen and inflamed skin lesions muscle stiffness pain, inflammation, or swelling in the calves, shoulders, or hands painful cold sores or blisters on the lips, nose, eyes, or genitals passing gas persistent breath odor or bad taste in your mouth rash with flat lesions or small raised lesions on the skin redness and swelling of the gums redness or swelling of the ears redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid runny or stuffy nose sensation of spinning shakiness in the legs, arms, hands, or feet shivering skin rash, encrusted, scaly, and oozing sleepiness or unusual drowsiness sneezing tender, swollen glands in the neck tenderness in the stomach area toothache trembling or shaking of the hands or feet trouble sleeping voice changes weight loss Incidence not known Decreased interest in sexual intercourse hair loss or thinning of the hair hives or welts inability to have or keep an erection increased sensitivity of the skin to sunlight loss in sexual ability, desire, drive, or performance muscle spasm redness of the skin redness or other discoloration of the skin severe sunburn tenderness of the salivary glands Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about eprosartan/hydrochlorothiazide Side Effects During Pregnancy Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: angiotensin II inhibitors with thiazides Consumer resources Eprosartan and Hydrochlorothiazide Other brands: Teveten HCT Professional resources Eprosartan and Hydrochlorothiazide (Wolters Kluwer) Related treatment guides High Blood Pressure} Drug Status Availability Discontinued D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA WADA Class Anti-Doping Classification Drug Class Angiotensin II inhibitors with thiazides Related Drugs High Blood Pressure amlodipine , lisinopril , hydrochlorothiazide , furosemide , losartan , metoprolol , atenolol , Lasix , Norvasc , valsartan , enalapril , Diovan , Cozaar , Benicar , Toprol-XL , Bystolic , irbesartan , Lopressor , hydrochlorothiazide / lisinopril , hydrochlorothiazide / triamterene , Maxzide , Zestril , Dyazide , More... 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