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evaluate Esbriet (Oral) Generic Name: pirfenidone (Oral route) pir-FEN-i-done Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons Commonly used brand name(s) In the U.S. Esbriet Available Dosage Forms: Capsule Tablet Therapeutic Class: Respiratory Agent Slideshow Insomnia and Sleep Deprivation: The Case For A Good Night's Sleep Uses For Esbriet Pirfenidone is used to treat idiopathic pulmonary fibrosis. This medicine is available only with your doctor's prescription. Before Using Esbriet In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of pirfenidone in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pirfenidone in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Ciprofloxacin Enoxacin Fluvoxamine Interferon Alfa-2b Mexiletine Peginterferon Alfa-2b Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Tobacco Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Kidney disease or Liver disease or Stomach or bowel problems Use with caution. May make these conditions worse. Proper Use of Esbriet Take this medicine exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions. It is best to take this medicine with food and at the same time each day. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage forms (capsules or tablets): For idiopathic pulmonary fibrosis: Adults On Days 1 to 7, 267 milligrams (mg) 3 times a day. On Days 8 to 14, 534 mg 3 times a day. On Day 15 and each day after, 801 mg 3 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 2403 mg per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose for 14 days or more, tell your doctor right away. You may need to start at a lower dose again. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Esbriet It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem. This medicine may make your skin more sensitive to sunlight. Use sunscreen or sunblock lotions with a sun protection factor (SPF) 50 or higher on a regular basis when you are outdoors. Wear protective clothing and hats and stay out of direct sunlight, especially between the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds. Check with your doctor right away if you have diarrhea, nausea, vomiting, heartburn, stomach pain or upset while using this medicine. Stop smoking before treatment with Esbriet and avoid smoking while you are using this medicine. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Esbriet Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Diarrhea itching or skin rash nausea redness or other discoloration of the skin severe sunburn stomach discomfort, upset, or pain vomiting Incidence not known Cough or hoarseness fever with or without chills general feeling of tiredness or weakness large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs lower back or side pain painful or difficult urination sore throat sores, ulcers, or white spots on the lips or in the mouth unusual bleeding or bruising Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach body aches or pain change in taste dizziness ear congestion headache heartburn or indigestion increased sensitivity of the skin to sunlight joint or muscle pain lack or loss of strength loss of appetite pain or tenderness around the eyes and cheekbones sneezing stuffy or runny nose trouble sleeping unusual tiredness or weakness weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Esbriet (pirfenidone) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: miscellaneous uncategorized agents Consumer resources Esbriet Professional resources Esbriet (AHFS Monograph) Esbriet (FDA) Related treatment guides Idiopathic Pulmonary Fibrosis} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug 3 years Approval History FDA approved 2014 Manufacturer Genentech, Inc. Drug Class Miscellaneous uncategorized agents Related Drugs Idiopathic Pulmonary Fibrosis Ofev , nintedanib , pirfenidone , Actimmune , interferon gamma-1b , More... Esbriet Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Esbriet Images Esbriet 267 mg (InterMune 267 mg ) View all images Related Questions & Answers What is the difference between ofev, nintedanib, esbriet & pirfenidone? I have lung disease and I am taking Esbriet capsule 267 three times a day.Is Clindamycin compatble? Read more questions} } wind up


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