searching for what you offer Obinutuzumab Generic Name: Obinutuzumab (oh bi nue TOOZ ue mab) Brand Name: Gazyva Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Warning In people who have had hepatitis B before or carry the virus, drugs like this one can cause the virus to become active. This can lead to very bad and sometimes deadly liver problems. You will be tested for hepatitis B before starting obinutuzumab, while on this medicine, and for a few months after obinutuzumab is stopped. A very bad brain problem called progressive multifocal leukoencephalopathy (PML) has happened with this medicine. It may cause disability or can be deadly. Tell your doctor right away if you have signs like confusion, memory problems, low mood (depression), change in the way you act, change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight. Uses of Obinutuzumab: It is used to treat a type of leukemia. It is used to treat a type of lymphoma. Slideshow 2016 New Drug Approvals: The Year That Was What do I need to tell my doctor BEFORE I take Obinutuzumab? If you have an allergy to obinutuzumab or any other part of obinutuzumab. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have an infection. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take obinutuzumab with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Obinutuzumab? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Side effects have happened during the infusion and within 24 hours after the infusion. Sometimes, these can be very bad or life-threatening. Tell your doctor if you have any bad side effects during or within 24 hours after the infusion. You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly. You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. Rarely, some bleeding problems have been deadly. Have blood work checked as you have been told by the doctor. Talk with the doctor. Talk with your doctor before getting any vaccines. Use with obinutuzumab may either raise the chance of an infection or make the vaccine not work as well. Heart problems have gotten worse in some people taking this medicine. Sometimes this has been deadly. If you have heart problems, talk with your doctor. If you are 65 or older, use obinutuzumab with care. You could have more side effects. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant. If you used obinutuzumab during pregnancy, tell your baby's doctor. You will need to discuss the safety and timing of certain vaccines with the doctor. Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby. How is this medicine (Obinutuzumab) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. It is given as an infusion into a vein over a period of time. Other drugs may be given before obinutuzumab to help avoid side effects. You will need to be sure that you are not dehydrated before getting this medicine. Check with your doctor to see if you need to drink extra fluids before getting obinutuzumab. What do I do if I miss a dose? Call your doctor to find out what to do. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal. Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Very bad headache. Feeling very tired or weak. Patients with cancer who take this medicine may be at a greater risk of getting a bad health problem called tumor lysis syndrome (TLS). Sometimes, this has been deadly. Call your doctor right away if you have a fast heartbeat or a heartbeat that does not feel normal; any passing out; trouble passing urine; muscle weakness or cramps; upset stomach, throwing up, loose stools, or not able to eat; or feel sluggish. Some people have side effects while getting obinutuzumab or within 24 hours after getting this medicine. Call your doctor right away if you have a fast heartbeat, fever, chills, muscle or joint pain, flushing or swelling of the face, upset stomach or throwing up, weakness, shortness of breath, dizziness or passing out, diarrhea, or chest pain or pressure. What are some other side effects of Obinutuzumab? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling tired or weak. Hard stools (constipation). Not hungry. Muscle or joint pain. Sinus pain. Signs of a common cold. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Obinutuzumab? If you need to store obinutuzumab at home, talk with your doctor, nurse, or pharmacist about how to store it. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take obinutuzumab or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to obinutuzumab. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about obinutuzumab Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: CD20 monoclonal antibodies Consumer resources Obinutuzumab Obinutuzumab Intravenous (Advanced Reading) Other brands: Gazyva Professional resources Obinutuzumab (AHFS Monograph) Obinutuzumab (Wolters Kluwer) Related treatment guides Follicular Lymphoma Chronic Lymphocytic Leukemia} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Obinutuzumab Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Drug Class CD20 monoclonal antibodies Related Drugs Chronic Lymphocytic Leukemia Rituxan , rituximab , cyclophosphamide , Imbruvica , Cytoxan , ibrutinib , bendamustine , Venclexta , Octagam , Leukeran , chlorambucil , Gazyva , More... Follicular Lymphoma Rituxan , rituximab , copanlisib , Gazyva , Zydelig , Intron A , idelalisib , Aliqopa , Rituxan Hycela , interferon alfa-2b , hyaluronidase / rituximab , More... Related: Chronic Lymphocytic Leukemia (CLL)} } expenses
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