tremendous albiglutide Generic Name: albiglutide (AL bi GLOO tide) Brand Name: Tanzeum Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A What is albiglutide? Albiglutide is an injectable diabetes medicine that helps control blood sugar levels. Albiglutide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Albiglutide is usually given after other diabetes medications have been tried without success. This medicine is not for treating type 1 diabetes. Albiglutide may also be used for purposes not listed in this medication guide. Slideshow Invokana Insights: 10 Drug-Specific Facts You Should Know What is the most important information I should know about albiglutide? You should not use albiglutide if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer). Do not use albiglutide if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). In animal studies, albiglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk. Call your doctor at once if you have signs of a thyroid tumor , such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath. What should I discuss with my healthcare provider before using albiglutide? You should not use albiglutide if you are allergic to it, or if you have: an endocrine system cancer called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2); a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or diabetic ketoacidosis (call your doctor for treatment with insulin). To make sure albiglutide is safe for you, tell your doctor if you have ever had: pancreatitis; stomach disorder such as slowed digestion; an intestinal disorder; liver or kidney disease; if you also use insulin or oral diabetes medicine; or if you have been sick with vomiting or diarrhea. In animal studies, albiglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk. Albiglutide may harm an unborn baby. Tell your doctor if you are pregnant. If you plan to get pregnant , you should stop using this medicine for at least 1 month before conception. Do not stop using albiglutide without asking your doctor about using a different medicine to treat your diabetes. It is not known whether albiglutide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. Do not give this medicine to anyone under 18 years old without medical advice. How should I use albiglutide? Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Albiglutide comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions. Albiglutide is injected under the skin. You will be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes. You may use albiglutide with or without food. The albiglutide prefilled injection pen comes in a strength of 30 milligrams (mg) or 50 mg. The pen contains powder medicine and a liquid that must be mixed before you give the injection. Each pen strength has a certain "wait" time to allow the powder to completely dissolve after mixing. The 30-mg pen needs 15 minutes of wait time, and the 50-mg pen needs 30 minutes of wait time Mixed medicine must be used within 8 hours. If you are using the injections at home, be sure you understand how to properly mix the medicine. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Do not mix albiglutide together with insulin in the same injection. Albiglutide is usually given only one time per week. Use the medicine on the same day each week if possible. Allow at least 4 days to pass between doses. Use a different place on your stomach, thigh, or upper arm each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row. Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another. Each single-use injection pen is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets. Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda. Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency. Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness. Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule. Storing unopened injection pens: Keep in the carton and store in a refrigerator, protected from light. Throw away any albiglutide not used before the expiration date on the medicine label. You may also store injection pens at room temperature, away from moisture and heat, for up to 4 weeks before use. Do not freeze albiglutide, and throw away the medication if it has become frozen. What happens if I miss a dose? Use the missed dose as soon as you remember. If you are more than 3 days late, skip the missed dose and use the medicine on your next regularly scheduled injection day. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe nausea and vomiting. What should I avoid while using albiglutide? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Albiglutide side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: symptoms of pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; signs of a thyroid tumor--swelling or a lump in your neck, trouble swallowing, a hoarse voice, or if you feel short of breath; low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath. Common side effects may include: nausea, diarrhea; cough, cold or flu symptoms; back pain, joint pain; or pain, swelling, or irritation where medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Albiglutide dosing information Usual Adult Dose for Diabetes Type 2: Initial dose: 30 mg subcutaneously once a week -If glycemic response is inadequate, may increase to 50 mg subcutaneously once a week Maintenance dose: 30 or 50 mg subcutaneously once a week Comments: -This drug is not recommended as first-line therapy because of uncertain relevance of the rodent C-cell tumor findings to humans; prescribe only to patients for whom the potential benefits are considered to outweigh the potential risk. -This drug has not been studied in patients with a history of pancreatitis; consider alternative therapies -The dose of concomitantly administered insulin or insulin secretagogues may need to be reduced when starting therapy in order to decrease the risk of hypoglycemia. -This drug has not been studied in combination with prandial insulin. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. What other drugs will affect albiglutide? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Other drugs may interact with albiglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using. Next Side Effects Print this page Add to My Med List More about albiglutide Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 11 Reviews Add your own review/rating Drug class: incretin mimetics Consumer resources Albiglutide Albiglutide Subcutaneous (Advanced Reading) Other brands: Tanzeum Professional resources Albiglutide (AHFS Monograph) Albiglutide (Wolters Kluwer) Related treatment guides Diabetes, Type 2 Where can I get more information? Your pharmacist can provide more information about albiglutide. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01. Last reviewed: September 22, 2017 Date modified: December 03, 2017} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Incretin mimetics Related Drugs Diabetes, Type 2 metformin , insulin aspart , glipizide , glimepiride , Januvia , pioglitazone , Victoza , Actos , Tradjenta , Glucophage , glyburide , Janumet , Invokana , Amaryl , Welchol , Onglyza , sitagliptin , Trulicity , Jardiance , Lantus , Farxiga , Levemir , Tresiba , Glucotrol , Bydureon , More... Albiglutide Rating 11 User Reviews 4.6 /10 11 User Reviews 4.6 Rate it! Help and Support Looking for answers? Ask a question or go join the albiglutide support group to connect with others who have similar interests.} } studying
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