up to date Anzemet (Oral) Generic Name: dolasetron (Oral route) doe-LAS-e-tron MES-i-late Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Anzemet Available Dosage Forms: Tablet Therapeutic Class: Antiemetic Pharmacologic Class: Dolasetron Slideshow Treatment of Opioid-Induced Constipation: The Hard Facts Uses For Anzemet Dolasetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation. Dolasetron works to block the signals to the brain that cause nausea and vomiting. This medicine is available only with your doctor's prescription. Before Using Anzemet In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of dolasetron in children 2 years of age and older. However, safety and efficacy have not been established in children younger than 2 years of age. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dolasetron in the elderly. However, elderly patients are more likely to have heart rhythm problems, which may require caution in patients receiving dolasetron. Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Amisulpride Apomorphine Bepridil Cisapride Dronedarone Levomethadyl Mesoridazine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acecainide Ajmaline Alfentanil Alfuzosin Almotriptan Amineptine Amiodarone Amitriptyline Amitriptylinoxide Amoxapine Amphetamine Anagrelide Aprindine Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Asenapine Astemizole Azimilide Azithromycin Benzphetamine Bretylium Brompheniramine Buprenorphine Buserelin Buspirone Butorphanol Carbamazepine Chloral Hydrate Chloroquine Chlorpheniramine Chlorpromazine Ciprofloxacin Citalopram Clarithromycin Clomipramine Clozapine Cocaine Codeine Crizotinib Cyclobenzaprine Dabrafenib Dasatinib Degarelix Delamanid Desipramine Deslorelin Desvenlafaxine Deutetrabenazine Dextroamphetamine Dextromethorphan Dibenzepin Dihydrocodeine Disopyramide Dofetilide Domperidone Donepezil Doxepin Droperidol Duloxetine Efavirenz Eletriptan Enflurane Erythromycin Escitalopram Fentanyl Fingolimod Flecainide Fluconazole Fluoxetine Fluvoxamine Foscarnet Frovatriptan Furazolidone Gatifloxacin Gemifloxacin Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Halothane Histrelin Hydrocodone Hydromorphone Hydroquinidine Hydroxychloroquine Hydroxytryptophan Hydroxyzine Ibutilide Iloperidone Imipramine Iproniazid Isocarboxazid Isoflurane Isradipine Ivabradine Ketoconazole Lacosamide Lapatinib Leuprolide Levofloxacin Levomilnacipran Levorphanol Lidoflazine Linezolid Lisdexamfetamine Lithium Lofepramine Lopinavir Lorcainide Lorcaserin Lumefantrine Mefloquine Melitracen Meperidine Methadone Methamphetamine Methylene Blue Metronidazole Mifepristone Milnacipran Mirtazapine Moclobemide Morphine Morphine Sulfate Liposome Moxifloxacin Nafarelin Nalbuphine Naratriptan Nefazodone Nilotinib Norfloxacin Nortriptyline Octreotide Ofloxacin Ondansetron Opipramol Oxycodone Oxymorphone Paliperidone Panobinostat Paroxetine Pasireotide Pazopanib Pentamidine Pentazocine Phenelzine Pimavanserin Pirmenol Pitolisant Posaconazole Prajmaline Probucol Procainamide Procarbazine Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Ranolazine Rasagiline Remifentanil Ribociclib Risperidone Rizatriptan Salmeterol Selegiline Sematilide Sertindole Sertraline Sevoflurane Sibutramine Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Spiramycin St John's Wort Sufentanil Sulfamethoxazole Sulpiride Sultopride Sumatriptan Sunitinib Tacrolimus Tapentadol Tedisamil Telavancin Telithromycin Tetrabenazine Tianeptine Toremifene Tramadol Tranylcypromine Trazodone Trifluoperazine Trimethoprim Trimipramine Triptorelin Tryptophan Vandetanib Vardenafil Vemurafenib Venlafaxine Vilazodone Vinflunine Voriconazole Vortioxetine Zolmitriptan Zotepine Zuclopenthixol Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Bradycardia (slow heartbeat) or Congestive heart failure or Kidney disease Patients with these conditions should be monitored with an electrocardiogram (ECG) while using this medicine. Congenital long QT syndrome (abnormal heart rhythm) or Heart block, without a pacemaker Should not be used in patients with these conditions. Heart disease or Heart rhythm problems (eg, atrial fibrillation, prolonged QT, PR, and QRS interval) or Sick sinus syndrome (type of abnormal heart rhythm) Use with caution. May increase risk for more serious heart rhythm problems (such as torsade de pointes) and additional monitoring is required. Hypokalemia (low potassium in the blood) or Hypomagnesemia (low magnesium in the blood) Must be corrected first before using this medicine. Proper Use of Anzemet Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If your child cannot swallow the tablets, the injection solution can be mixed with apple or apple-grape juice and taken by mouth. The mixture may be stored for up to 2 hours at room temperature before use. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For prevention of nausea and vomiting after cancer medicines: Adults 100 milligrams (mg) given within 1 hour before starting cancer treatment. Children 2 to 16 years of age Dose is based on body weight and must be determined by your doctor. The dose is usually 1.8 milligrams (mg) per kilogram (kg) of body weight given within 1 hour before starting cancer treatment. However, the dose is usually not more than 100 mg. Children younger than 2 years of age Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of this medicine, and you feel nauseated or you vomit, take the missed dose as soon as possible. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Anzemet Check with your doctor if severe nausea and vomiting continue after leaving the hospital or cancer treatment center. This medicine can cause changes heart rhythms, such as conditions called QT, PR, and QRS prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients. Contact your doctor right away if you have a fast, pounding, or irregular heartbeats. Dolasetron may cause a serious condition called serotonin syndrome if taken together with some medicines such as fentanyl (Abstral , Duragesic ), lithium (Eskalith , Lithobid ), a MAO inhibitor (such as methylene blue injection, Eldepryl , Marplan , Nardil , Parnate ), medicine to treat migraine headaches, or medicine to treat depression (eg, fluoxetine, mirtazapine, paroxetine, Celexa , Effexor , Lexapro , Paxil , Zoloft ). Check with your doctor first before taking any other medicines with dolasetron . Do not stop taking this medicine without checking first with your doctor . Your doctor may gradually reduce the amount you are using before stopping completely. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Anzemet Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Chest pain or discomfort lightheadedness, dizziness, or fainting slow or irregular heartbeat unusual tiredness or weakness Less common Chills decrease in the amount of urine fast, pounding, or irregular heartbeat or pulse fever Rare Agitation black, tarry stools bleeding gums bloating or swelling of the face, arms, hands, lower legs, or feet blood in the urine or stools blurred vision burning while urinating changes in skin color confusion cough delirium depression diarrhea difficult or labored breathing difficult or painful urination difficulty with swallowing dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position feeling of warmth feeling uncoordinated frequent urination hallucinations headache hives or welts, itching, or skin rash increased volume of pale, dilute urine irritability lethargy muscle twitching nausea noisy breathing numbness and tingling of the face, fingers, or toes pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion pain, tenderness, or swelling of the foot or leg pale skin pale, bluish-colored, or cold hands or feet pinpoint red or purple spots on the skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue rapid weight gain red skin rigid muscles seizures sweating swelling of the face, ankles, or hands tightness in the chest tingling of the hands or feet tremor troubled breathing with exertion unusual bleeding or bruising unusual weight gain or loss vomiting weak or absent pulses in the legs Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Belching heartburn indigestion pain stomach discomfort, upset, or pain Rare Abnormal dreams bad, unusual, or unpleasant (after) taste bloating bloody nose change in taste changes in vision continuing ringing or buzzing or other unexplained noise in the ears darkened urine difficulty having a bowel movement (stool) difficulty seeing at night difficulty with moving feeling of constant movement of self or surroundings feeling of unreality hearing loss increased sensitivity of the eyes to sunlight increased sweating joint pain loss of appetite muscle aching or cramping muscle pain or stiffness pain or burning sensation at the injection site pains in the stomach, side, or abdomen, possibly radiating to the back redness of the face, neck, arms, and occasionally, upper chest sensation of spinning sense of detachment from self or body shakiness and unsteady walk shakiness in the legs, arms, hands, or feet swollen joints unsteadiness, trembling, or other problems with muscle control or coordination weight loss yellow eyes or skin Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Anzemet (dolasetron) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons 0 Reviews Add your own review/rating Drug class: 5HT3 receptor antagonists Consumer resources Anzemet Anzemet injection Anzemet (Dolasetron Injection) Anzemet (Dolasetron Tablets) Anzemet (Advanced Reading) Professional resources Anzemet (AHFS Monograph) Anzemet (FDA) Anzemet Injection (FDA) Related treatment guides Nausea/Vomiting, Postoperative Nausea/Vomiting, Chemotherapy Induced} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug 10 + years Approval History FDA approved 1997 Drug Class 5HT3 receptor antagonists Related Drugs Nausea / Vomiting, Chemotherapy Induced lorazepam , ondansetron , Zofran , Ativan , dexamethasone , metoclopramide , Reglan , Decadron , Marinol , dronabinol , More... Nausea / Vomiting, Postoperative ondansetron , Zofran , metoclopramide , Reglan , Zofran ODT , Emend , Aloxi , granisetron , palonosetron , droperidol , Kytril , aprepitant , More... Anzemet Rating No Reviews - Be the first! 10 /10 No Reviews - Be the first! 10 Rate it! Anzemet Images Anzemet 50 mg (ANZEMET 50 ) View all images Help and Support Looking for answers? Ask a question or go join the Anzemet support group to connect with others who have similar interests.} } this sort of
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